Peter Frommolt

Peter Frommolt

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Peter Frommolt

Peter Frommolt

Publications by authors named "Peter Frommolt"

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KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants.

Nat Commun 2019 Jul 25;10(1):3323. Epub 2019 Jul 25.

Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases (CECAD) and Institute for Mitochondrial Diseases and Ageing, Medical Faculty, University of Cologne, D-50931, Cologne, Germany.

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http://dx.doi.org/10.1038/s41467-019-11275-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658563PMC
July 2019

Modeling the Pathological Long-Range Regulatory Effects of Human Structural Variation with Patient-Specific hiPSCs.

Cell Stem Cell 2019 May 11;24(5):736-752.e12. Epub 2019 Apr 11.

Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), University of Cantabria, Cantabria, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.03.004DOI Listing
May 2019

Functional Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in .

Cells 2019 01 19;8(1). Epub 2019 Jan 19.

Institute of Biochemistry I, Medical Faculty, University Hospital Cologne, 50931 Cologne, Germany.

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http://dx.doi.org/10.3390/cells8010072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356199PMC
January 2019

s ·nr: a visual analytics framework for contextual analyses of private and public RNA-seq data.

BMC Genomics 2019 Jan 24;20(1):85. Epub 2019 Jan 24.

University of Southern Denmark, Department of Biochemistry and Molecular Biology, Campusvej 55, Odense, DK-5230, Denmark.

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http://dx.doi.org/10.1186/s12864-018-5396-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346532PMC
January 2019

Integrative analysis and machine learning on cancer genomics data using the Cancer Systems Biology Database (CancerSysDB).

BMC Bioinformatics 2018 04 24;19(1):156. Epub 2018 Apr 24.

Bioinformatics Facility, CECAD Research Center, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1186/s12859-018-2157-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921751PMC
April 2018

Semi-automated cancer genome analysis using high-performance computing.

Hum Mutat 2017 10 17;38(10):1325-1335. Epub 2017 Jul 17.

Bioinformatics Core Facility, Cluster of Excellence on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/humu.23275DOI Listing
October 2017

Challenges in the Setup of Large-scale Next-Generation Sequencing Analysis Workflows.

Comput Struct Biotechnol J 2017 25;15:471-477. Epub 2017 Oct 25.

Bioinformatics Core Facility, CECAD Research Center, University of Cologne, Germany.

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http://dx.doi.org/10.1016/j.csbj.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683667PMC
October 2017

PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation.

Cell Stem Cell 2017 05 9;20(5):689-705.e9. Epub 2017 Mar 9.

Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Strasse 21, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.02.004DOI Listing
May 2017

Epigenomics-Based Identification of Major Cell Identity Regulators within Heterogeneous Cell Populations.

Cell Rep 2016 12;17(11):3062-3076

Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Strasse 21, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD) Research Center and Systems Biology of Ageing Cologne, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.046DOI Listing
December 2016

The founder-cell transcriptome in the Arabidopsis apetala1 cauliflower inflorescence meristem.

BMC Genomics 2016 11 3;17(1):855. Epub 2016 Nov 3.

Institute of Developmental Biology, University of Cologne, Cologne Biocenter, Zuelpicher Strasse 47b, D-50674, Cologne, Germany.

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http://dx.doi.org/10.1186/s12864-016-3189-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093967PMC
November 2016

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.

Cell 2016 Mar;165(1):125-138

Department of Neuronal Control of Metabolism, Max Planck Institute for Metabolism Research, Gleueler Strasse 50, 50931 Cologne, Germany; Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Strasse 26, 50924 Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany; National Center for Diabetes Research (DZD) Ingolstädter Land Strasse 1, 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.02.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157157PMC
March 2016

Foxd3 Promotes Exit from Naive Pluripotency through Enhancer Decommissioning and Inhibits Germline Specification.

Cell Stem Cell 2016 Jan;18(1):118-33

Center for Molecular Medicine Cologne, University of Cologne, Robert-Koch-Strasse 21, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909150041
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048917PMC
http://dx.doi.org/10.1016/j.stem.2015.09.010DOI Listing
January 2016

Interplay among Drosophila transcription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy.

Dis Model Mech 2015 Oct 6;8(10):1279-93. Epub 2015 Aug 6.

Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany

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http://dx.doi.org/10.1242/dmm.020719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610234PMC
October 2015

CoNCoS: copy number estimation in cancer with controlled support.

J Bioinform Comput Biol 2015 Oct 4;13(5):1550027. Epub 2015 Sep 4.

Cluster of Excellence on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.

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http://www.worldscientific.com/doi/abs/10.1142/S021972001550
Publisher Site
http://dx.doi.org/10.1142/S0219720015500274DOI Listing
October 2015

QuickNGS elevates Next-Generation Sequencing data analysis to a new level of automation.

BMC Genomics 2015 Jul 1;16:487. Epub 2015 Jul 1.

Bioinformatics Core Facility, CECAD Research Center, University of Cologne, Joseph-Stelzmann-Str. 26, 50931, Cologne, Germany.

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http://www.biomedcentral.com/1471-2164/16/487
Publisher Site
http://dx.doi.org/10.1186/s12864-015-1695-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486389PMC
July 2015

Wormpath: searching for molecular interaction networks in Caenorhabditis elegans.

Source Code Biol Med 2015 2;10. Epub 2015 Apr 2.

CECAD Research Center, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany ; Systems Biology of Aging Cologne (SyBACol), University of Cologne, Cologne, Germany ; Institute for Genome Stability in Aging and Disease, Medical Faculty, University of Cologne, Cologne, Germany ; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1186/s13029-015-0034-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392734PMC
April 2015

DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage.

Nat Cell Biol 2014 Dec 24;16(12):1168-1179. Epub 2014 Nov 24.

Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany.

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http://dx.doi.org/10.1038/ncb3071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250074PMC
December 2014

CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins.

J Cell Biol 2014 Oct;207(2):213-23

Institute for Genetics, Center for Molecular Medicine, Cologne Center for Genomics, and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, 50923 Cologne, Germany Institute for Genetics, Center for Molecular Medicine, Cologne Center for Genomics, and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, 50923 Cologne, Germany Institute for Genetics, Center for Molecular Medicine, Cologne Center for Genomics, and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, 50923 Cologne, Germany

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http://dx.doi.org/10.1083/jcb.201403129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210445PMC
October 2014

Deciphering the genetic basis of microcystin tolerance.

BMC Genomics 2014 Sep 9;15:776. Epub 2014 Sep 9.

University of Cologne, Cologne Biocenter, Aquatic Chemical Ecology, Zuelpicher Str, 47b, 50674 Cologne, Germany.

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http://dx.doi.org/10.1186/1471-2164-15-776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168211PMC
September 2014

Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner.

Aging Cell 2013 Aug 15;12(4):593-603. Epub 2013 May 15.

Department 2 of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1111/acel.12081DOI Listing
August 2013

Activating transcription factor 3 regulates immune and metabolic homeostasis.

Mol Cell Biol 2012 Oct 30;32(19):3949-62. Epub 2012 Jul 30.

Institute for Genetics and Cologne Excellence Cluster in Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1128/MCB.00429-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457521PMC
October 2012

Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.

Nat Genet 2012 May 27;44(7):740-2. Epub 2012 May 27.

Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1038/ng.2299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386896PMC
May 2012

Assessing the enrichment performance in targeted resequencing experiments.

Hum Mutat 2012 Apr 28;33(4):635-41. Epub 2012 Feb 28.

Cologne Cluster of Excellence on Cellular Stress Responses in Aging-Associated Diseases, Universität zu Köln, Cologne, Germany.

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http://dx.doi.org/10.1002/humu.22036DOI Listing
April 2012

Image quality of digital direct flat-panel mammography versus an indirect small-field CCD technique using a high-contrast phantom.

Int J Breast Cancer 2011 17;2011:701054. Epub 2010 Oct 17.

Department of Radiology, Medical School, University of Cologne, Kerpenerstraße 62, 50924 Cologne, Germany.

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http://dx.doi.org/10.4061/2011/701054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276250PMC
February 2012

Methyl-L-11C-methionine PET as a diagnostic marker for malignant progression in patients with glioma.

J Nucl Med 2009 Dec 12;50(12):1962-8. Epub 2009 Nov 12.

Max Planck Institute for Neurological Research with Klaus Joachim Zülch Laboratories, Cologne, Germany.

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http://dx.doi.org/10.2967/jnumed.109.065904DOI Listing
December 2009

Resampling in multiple-dose factorial designs.

Biom J 2009 Dec;51(6):915-31

Cologne Center for Genomics, Universität zu Köln, Zülpicher Strasse 47, 50674 Köln, Germany.

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http://dx.doi.org/10.1002/bimj.200900129DOI Listing
December 2009

Standardized high-throughput evaluation of cell-based compound screens.

BMC Bioinformatics 2008 Nov 12;9:475. Epub 2008 Nov 12.

Institute of Medical Statistics, Informatics and Epidemiology, University of Köln, Köln, Germany.

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http://dx.doi.org/10.1186/1471-2105-9-475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639430PMC
November 2008

Decreased number of circulating progenitor cells in obesity: beneficial effects of weight reduction.

Eur Heart J 2008 Jun 30;29(12):1560-8. Epub 2008 May 30.

Department of Internal Medicine III, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehn213DOI Listing
June 2008