Peter E Lobie

Peter E Lobie

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Peter E Lobie

Publications by authors named "Peter E Lobie"

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Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.

Nat Nanotechnol 2019 Jul 24;14(7):719-727. Epub 2019 Jun 24.

Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Biomedical Engineering, Faculty of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

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http://dx.doi.org/10.1038/s41565-019-0472-4DOI Listing
July 2019

Long noncoding RNA Linc00460 promotes breast cancer progression by regulating the miR-489-5p/FGF7/AKT axis.

Cancer Manag Res 2019 1;11:5983-6001. Epub 2019 Jul 1.

Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.

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http://dx.doi.org/10.2147/CMAR.S207084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612969PMC
July 2019

Synthesis of CC, CN coupled novel substituted dibutyl benzothiazepinone derivatives and evaluation of their thrombin inhibitory activity.

Bioorg Chem 2019 Jun 5;87:142-154. Epub 2019 Mar 5.

Department of Chemistry, Bangalore University, Central College Campus, Palace Road, Bangalore 560001, India; Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00452068183064
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http://dx.doi.org/10.1016/j.bioorg.2019.03.004DOI Listing
June 2019

XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation.

Oncogene 2019 02 1;38(9):1448-1460. Epub 2018 Oct 1.

Department of Pathology, Anhui Medical University, 230032, Hefei, Anhui, China.

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http://dx.doi.org/10.1038/s41388-018-0513-8DOI Listing
February 2019

Amplification of hsa-miR-191/425 locus promotes breast cancer proliferation and metastasis by targeting DICER1.

Carcinogenesis 2018 12;39(12):1506-1516

Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, P.R. China.

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http://dx.doi.org/10.1093/carcin/bgy102DOI Listing
December 2018

Loss of Estrogen-Regulated at 3p21.1 Promotes Tamoxifen Resistance in Breast Cancer.

Cancer Res 2018 Sep 26;78(17):4915-4928. Epub 2018 Jun 26.

Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-0069DOI Listing
September 2018

NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression.

Oncogene 2018 08 21;37(35):4887-4900. Epub 2018 May 21.

Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230027, China.

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http://dx.doi.org/10.1038/s41388-018-0280-6DOI Listing
August 2018

Synthesis, characterization and cytotoxicity studies of 1,2,3-triazoles and 1,2,4-triazolo [1,5-a] pyrimidines in human breast cancer cells.

Bioorg Med Chem Lett 2018 07 9;28(13):2314-2319. Epub 2018 May 9.

Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru 570006, India. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.05.020DOI Listing
July 2018

Bad phosphorylation as a target of inhibition in oncology.

Cancer Lett 2018 02 23;415:177-186. Epub 2017 Nov 23.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Tsinghua Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, Guangdong, PR China; National University Cancer Institute, National University Health System, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.11.017DOI Listing
February 2018

Triple negative breast cancer in Asia: An insider's view.

Cancer Treat Rev 2018 Jan 10;62:29-38. Epub 2017 Nov 10.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; National University Cancer Institute, National University Health System, Singapore; Curtin Medical School, Faculty of Health Sciences, Curtin University, Perth, WA, Australia; Medical Science Cluster, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2017.10.014DOI Listing
January 2018

The GDNF Family: A Role in Cancer?

Neoplasia 2018 01 12;20(1):99-117. Epub 2017 Dec 12.

The Centre for Biomedical and Chemical Sciences, School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2017.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730419PMC
January 2018

Autocrine hGH stimulates oncogenicity, epithelial-mesenchymal transition and cancer stem cell-like behavior in human colorectal carcinoma.

Oncotarget 2017 Nov 10;8(61):103900-103918. Epub 2017 Oct 10.

Cancer Science Institute of Singapore and Department of Pharmacology, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.18632/oncotarget.21812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732775PMC
November 2017

modulates s-mediated autophagy in human luminal breast cancer cell lines.

Oncotarget 2017 Oct 19;8(46):80709-80721. Epub 2017 Sep 19.

Department of Pathology, Anhui Medical University, Hefei, Anhui, China.

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http://dx.doi.org/10.18632/oncotarget.21080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655233PMC
October 2017

Tumour-Derived Human Growth Hormone As a Therapeutic Target in Oncology.

Trends Endocrinol Metab 2017 08 13;28(8):587-596. Epub 2017 Jun 13.

Cancer Science Institute of Singapore and Department of Pharmacology, National University of Singapore, 117456 Singapore; Tsinghua Berkeley Shenzhen Institute, Tsinghua University Graduate School, Shenzhen, PR China. Electronic address:

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http://www.cell.com/trends/endocrinology-metabolism/pdf/S104
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http://linkinghub.elsevier.com/retrieve/pii/S104327601730067
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http://dx.doi.org/10.1016/j.tem.2017.05.003DOI Listing
August 2017

Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells.

J Biol Chem 2017 08 21;292(33):13551-13564. Epub 2017 Jun 21.

From the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China,

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http://dx.doi.org/10.1074/jbc.M117.780973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566515PMC
August 2017

XIAP 3'-untranslated region serves as a competitor for HMGA2 by arresting endogenous let-7a-5p in human hepatocellular carcinoma.

Tumour Biol 2017 Jul;39(7):1010428317719578

2 Department of Pathology, Anhui Medical University, Hefei, China.

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http://dx.doi.org/10.1177/1010428317719578DOI Listing
July 2017

Autocrine Prolactin Stimulates Endometrial Carcinoma Growth and Metastasis and Reduces Sensitivity to Chemotherapy.

Endocrinology 2017 06;158(6):1595-1611

CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.

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http://dx.doi.org/10.1210/en.2016-1903DOI Listing
June 2017

Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent.

Oncotarget 2017 Jun;8(24):39323-39344

Cancer Science Institute of Singapore and Department of Pharmacology, National University of Singapore, Singapore.

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http://dx.doi.org/10.18632/oncotarget.16950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503616PMC
June 2017

Autocrine Human Growth Hormone Promotes Invasive and Cancer Stem Cell-Like Behavior of Hepatocellular Carcinoma Cells by STAT3 Dependent Inhibition of CLAUDIN-1 Expression.

Int J Mol Sci 2017 Jun 15;18(6). Epub 2017 Jun 15.

Cancer Science Institute of Singapore and Department of Pharmacology, National University of Singapore, Singapore 119077, Singapore.

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http://dx.doi.org/10.3390/ijms18061274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486096PMC
June 2017

WNT4 mediates the autocrine effects of growth hormone in mammary carcinoma cells.

Endocr Relat Cancer 2016 07 20;23(7):571-85. Epub 2016 Jun 20.

Centre de Recherche en Cancérologie de LyonUMR INSERM 1052-CNRS 5286, Centre Léon Bérard, Université Claude Bernard Lyon I, Université de Lyon, Lyon, France

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http://dx.doi.org/10.1530/ERC-15-0528DOI Listing
July 2016

Trefoil Factor-3 (TFF3) Stimulates De Novo Angiogenesis in Mammary Carcinoma both Directly and Indirectly via IL-8/CXCR2.

PLoS One 2015 11;10(11):e0141947. Epub 2015 Nov 11.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141947PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641663PMC
June 2016

CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance.

Cell Res 2016 06 22;26(6):655-73. Epub 2016 Mar 22.

The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.

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http://dx.doi.org/10.1038/cr.2016.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897177PMC
June 2016

microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer.

Biol Rev Camb Philos Soc 2016 May 28;91(2):409-28. Epub 2015 Jan 28.

Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.

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http://dx.doi.org/10.1111/brv.12176DOI Listing
May 2016

GHR/PRLR Heteromultimer Is Composed of GHR Homodimers and PRLR Homodimers.

Mol Endocrinol 2016 May 22;30(5):504-17. Epub 2016 Mar 22.

Department of Medicine (Y.L., Y.Z., J.J., S.J.F.), Division of Endocrinology, Diabetes, and Metabolism; Department of Radiology (K.R.Z.); and Department of Cell, Developmental, and Integrative Biology (S.J.F.), University of Alabama at Birmingham, Birmingham, Alabama 35294; Cancer Science Institute of Singapore and Department of Pharmacology (P.E.L.), National University of Singapore, Singapore 119077; Department of Radiology (R.P.), Stanford University School of Medicine, Palo Alto, California 94304; Department of Biological Sciences (J.F.L., W.Y.C.), Clemson University, Clemson, South Carolina 29634; and Endocrinology Section (S.J.F.), Medical Service, Veterans Affairs Medical Center, Birmingham, Alabama 35233.

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http://dx.doi.org/10.1210/me.2015-1319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853563PMC
May 2016

Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma.

Oncotarget 2016 May;7(20):29465-79

The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, Anhui, China.

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http://dx.doi.org/10.18632/oncotarget.8781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045410PMC
May 2016

ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation.

Oncotarget 2016 May;7(19):27007-20

Department of Physiology, Yong Loo Lin School of Medicine, National University Health System (NUHS), National University of Singapore (NUS), Singapore.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053628PMC
http://dx.doi.org/10.18632/oncotarget.8875DOI Listing
May 2016

Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma.

Oncotarget 2016 Jan;7(3):3267-82

The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, China.

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http://dx.doi.org/10.18632/oncotarget.6572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823105PMC
January 2016

Autocrine human growth hormone stimulates the tumor initiating capacity and metastasis of estrogen receptor-negative mammary carcinoma cells.

Cancer Lett 2015 Sep 9;365(2):182-9. Epub 2015 Jun 9.

Department of Pharmacology, National University of Singapore, Singapore; Cancer Science Institute of Singapore, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.05.031DOI Listing
September 2015

Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.

PLoS One 2014 23;9(12):e114507. Epub 2014 Dec 23.

Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Life Sciences, 28 Medical Drive, Singapore, 117456, Singapore; Astar-Bioprocessing Technology Institute, 20 Biopolis Way, 138668, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114507PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275173PMC
August 2015

Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashion.

Am J Physiol Gastrointest Liver Physiol 2015 Aug 4;309(3):G146-61. Epub 2015 Jun 4.

Esophageal Diseases Center, Veterans Affairs North Texas Health Care System and the University of Texas Southwestern Medical Center, Dallas, Texas; Department of Medicine, Veterans Affairs North Texas Health Care System and the University of Texas Southwestern Medical Center, Dallas, Texas; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas;

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http://dx.doi.org/10.1152/ajpgi.00462.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525109PMC
August 2015

Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer.

J Biol Chem 2015 May 14;290(22):13812-29. Epub 2015 Apr 14.

From the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, Anhui 230027, China, the Hefei National Laboratory for Physical Sciences at Microscale, Hefei, Anhui 230027, China,

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http://dx.doi.org/10.1074/jbc.M115.653261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447958PMC
May 2015

Trefoil factor 3 as a novel biomarker to distinguish between adenocarcinoma and squamous cell carcinoma.

Medicine (Baltimore) 2015 May;94(20):e860

From the Department of Pathology (X-NW, S-JW, PC, QL, Z-SW, QW); Laboratory of Pathogenic Microbiology and Immunology, Anhui Medical University, Hefei, Anhui, People's Republic of China (X-NW); Cancer Science Institute of Singapore and Department of Pharmacology, National University of Singapore (VP, PEL); and National Cancer Institute of Singapore, National University Health System, Singapore (PEL). *These authors contributed equally to this work.

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http://dx.doi.org/10.1097/MD.0000000000000860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602872PMC
May 2015

Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor.

Nat Commun 2015 Jan 23;6:5988. Epub 2015 Jan 23.

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China and Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100190, China.

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http://dx.doi.org/10.1038/ncomms6988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354030PMC
January 2015

Dynamic analysis of GH receptor conformational changes by split luciferase complementation.

Mol Endocrinol 2014 Nov 4;28(11):1807-19. Epub 2014 Sep 4.

Department of Medicine (Y.L., P.A.B., Y.Z., J.J., S.J.F.), Division of Endocrinology, Diabetes, and Metabolism, and Departments of Radiology (K.R.Z.), and Cell, Developmental, and Integrative Biology (S.J.F.), University of Alabama at Birmingham, Birmingham, Alabama 35294; Cancer Science Institute of Singapore and Department of Pharmacology (P.E.L.), National University of Singapore, Singapore 119077; Department of Radiology (R.P.), Stanford University School of Medicine, Palo Alto, California 94304; Department of Biological Sciences (J.F.L., W.Y.C.), Clemson University, Clemson, South Carolina 29634; and Endocrinology Section (S.J.F.), Medical Service, Veterans Affairs Medical Center, Birmingham, Alabama 35233.

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http://dx.doi.org/10.1210/me.2014-1153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213363PMC
November 2014

Artemin, a member of the glial cell line-derived neurotrophic factor family of ligands, is HER2-regulated and mediates acquired trastuzumab resistance by promoting cancer stem cell-like behavior in mammary carcinoma cells.

J Biol Chem 2014 Jun 15;289(23):16057-71. Epub 2014 Apr 15.

From the Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China,

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http://dx.doi.org/10.1074/jbc.M113.529552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047380PMC
June 2014

SHON is a novel estrogen-regulated oncogene in mammary carcinoma that predicts patient response to endocrine therapy.

Cancer Res 2013 Dec;73(23):6951-62

Authors' Affiliations: Liggins Institute, University of Auckland, Auckland, New Zealand; Department of Clinical Oncology; Department of Histopathology, School of Molecular Medical Sciences, University of Nottingham and Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; The Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University; The Institute of Genetics and Cytology, Northeast Normal University, Changchun; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing; Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China; Department of Pathology, Anhui Medical University, Hefei, China; Cancer Science Institute of Singapore, and Department of Pharmacology, National University of Singapore; and National Cancer Institute of Singapore, National University Health System, Singapore.

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http://cancerres.aacrjournals.org/content/73/23/6951.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-0982DOI Listing
December 2013

DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts.

Front Genet 2013 Dec 4;4:265. Epub 2013 Dec 4.

Cancer Science Institute of Singapore, National University of Singapore Singapore, Singapore.

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http://dx.doi.org/10.3389/fgene.2013.00265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849743PMC
December 2013

Growth hormone and cancer: an update on progress.

Curr Opin Endocrinol Diabetes Obes 2013 Aug;20(4):307-13

Liggins Institute, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1097/MED.0b013e328363183aDOI Listing
August 2013

c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2.

J Biol Chem 2013 Jun 6;288(25):18121-33. Epub 2013 May 6.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.

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http://dx.doi.org/10.1074/jbc.M113.478560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689956PMC
June 2013

Nanotoxicity: a growing need for study in the endocrine system.

Small 2013 May 11;9(9-10):1654-71. Epub 2013 Feb 11.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026, China.

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http://doi.wiley.com/10.1002/smll.201201517
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http://dx.doi.org/10.1002/smll.201201517DOI Listing
May 2013

MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression.

PLoS One 2012 2;7(8):e41523. Epub 2012 Aug 2.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, PR China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041523PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410899PMC
January 2013

Prognostic significance of the expression of GFRα1, GFRα3 and syndecan-3, proteins binding ARTEMIN, in mammary carcinoma.

BMC Cancer 2013 Jan 26;13:34. Epub 2013 Jan 26.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.

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http://dx.doi.org/10.1186/1471-2407-13-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562211PMC
January 2013

The prolactin receptor mediates HOXA1-stimulated oncogenicity in mammary carcinoma cells.

Int J Oncol 2012 Dec 15;41(6):2285-95. Epub 2012 Oct 15.

Liggins Institute, University of Auckland, Auckland 1023, New Zealand.

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http://dx.doi.org/10.3892/ijo.2012.1660DOI Listing
December 2012

Loss of SNAIL regulated miR-128-2 on chromosome 3p22.3 targets multiple stem cell factors to promote transformation of mammary epithelial cells.

Cancer Res 2012 Nov 26;72(22):6036-50. Epub 2012 Sep 26.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, PR China.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-1507DOI Listing
November 2012

14-3-3σ mediates G2-M arrest produced by 5-aza-2'-deoxycytidine and possesses a tumor suppressor role in endometrial carcinoma cells.

Gynecol Oncol 2012 Oct 5;127(1):231-40. Epub 2012 Jul 5.

Liggins Institute, Auckland University, Auckland, New Zealand.

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http://dx.doi.org/10.1016/j.ygyno.2012.06.039DOI Listing
October 2012

Autocrine human GH promotes radioresistance in mammary and endometrial carcinoma cells.

Endocr Relat Cancer 2012 Oct 14;19(5):625-44. Epub 2012 Sep 14.

The Liggins Institute, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1530/ERC-12-0042DOI Listing
October 2012

ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma.

Breast Cancer Res 2011 7;13(6):R112. Epub 2011 Nov 7.

Liggins Institute, University of Auckland, 2-6 Park Avenue, Auckland, 1023, New Zealand.

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http://dx.doi.org/10.1186/bcr3054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326554PMC
June 2012

Inhibitory GH receptor extracellular domain monoclonal antibodies: three-dimensional epitope mapping.

Endocrinology 2011 Dec 11;152(12):4777-88. Epub 2011 Oct 11.

Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-0012, USA.

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http://dx.doi.org/10.1210/en.2011-1336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230063PMC
December 2011

Tumor expression of human growth hormone and human prolactin predict a worse survival outcome in patients with mammary or endometrial carcinoma.

J Clin Endocrinol Metab 2011 Oct 17;96(10):E1619-29. Epub 2011 Aug 17.

Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei, Anhui 230027, People’s Republic of China.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2011-1245DOI Listing
October 2011

Pivotal role of reduced let-7g expression in breast cancer invasion and metastasis.

Cancer Res 2011 Oct 25;71(20):6463-74. Epub 2011 Aug 25.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, PR China.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1322DOI Listing
October 2011

Autocrine proliferative effects of hGH are maintained in primary cultures of human mammary carcinoma cells.

J Clin Endocrinol Metab 2011 Sep 6;96(9):E1418-26. Epub 2011 Jul 6.

Centre Hospitalier Universitaire de Nîmes, Laboratoire de Cytogénétique, Hôpital Caremeau, 30029 Nîmes, France.

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http://dx.doi.org/10.1210/jc.2011-0473DOI Listing
September 2011

Autocrine human growth hormone reduces mammary and endometrial carcinoma cell sensitivity to mitomycin C.

Oncol Rep 2011 Aug 11;26(2):487-93. Epub 2011 May 11.

Liggins Institute, University of Auckland, Auckland 1023, New Zealand.

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http://dx.doi.org/10.3892/or.2011.1305DOI Listing
August 2011

miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway.

FEBS Lett 2011 Jul 7;585(14):2229-34. Epub 2011 Jun 7.

Laboratory of Molecular Tumor Pathology, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.

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http://dx.doi.org/10.1016/j.febslet.2011.05.042DOI Listing
July 2011

Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complex.

Mol Endocrinol 2011 Apr 10;25(4):597-610. Epub 2011 Feb 10.

Department of Medicine, University of Alabama at Birmingham, Alabama 35294-0012, USA.

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http://dx.doi.org/10.1210/me.2010-0255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063080PMC
April 2011

The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells.

Hum Reprod 2010 Nov 7;25(11):2859-69. Epub 2010 Sep 7.

The Liggins Institute, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1093/humrep/deq238DOI Listing
November 2010

STAT3alpha is oncogenic for endometrial carcinoma cells and mediates the oncogenic effects of autocrine human growth hormone.

Endocrinology 2010 Sep 28;151(9):4133-45. Epub 2010 Jul 28.

Liggins Institute, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1142, New Zealand.

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http://dx.doi.org/10.1210/en.2010-0273DOI Listing
September 2010

Artemin-stimulated progression of human non-small cell lung carcinoma is mediated by BCL2.

Mol Cancer Ther 2010 Jun 8;9(6):1697-708. Epub 2010 Jun 8.

Liggins Institute, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-1077DOI Listing
June 2010

Growth hormone internalization in mitochondria decreases respiratory chain activity.

Neuroendocrinology 2010 17;91(1):16-26. Epub 2009 Dec 17.

IFR 41, CNRS UMR 5123, Physiologie Intégrative Cellulaire et Moléculaire, Université de Lyon, Villeurbanne, France.

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https://www.karger.com/Article/FullText/268289
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http://dx.doi.org/10.1159/000268289DOI Listing
March 2010

Artemin stimulates oncogenicity and invasiveness of human endometrial carcinoma cells.

Endocrinology 2010 Mar 29;151(3):909-20. Epub 2010 Jan 29.

The Liggins Institute, University of Auckland, 2-6 Park Avenue, Private Bag 92019 Auckland, New Zealand.

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http://dx.doi.org/10.1210/en.2009-0979DOI Listing
March 2010

PAX5alpha enhances the epithelial behavior of human mammary carcinoma cells.

Mol Cancer Res 2010 Mar 2;8(3):444-56. Epub 2010 Mar 2.

The Liggins Institute, The University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1158/1541-7786.MCR-09-0368DOI Listing
March 2010

Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior.

Endocrinology 2010 Jan 4;151(1):43-55. Epub 2009 Dec 4.

The Liggins Institute, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand.

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http://dx.doi.org/10.1210/en.2009-0651DOI Listing
January 2010

Regulation of invasive growth: similar epigenetic mechanisms underpin tumour progression and implantation in human pregnancy.

Clin Sci (Lond) 2009 Dec 23;118(7):451-7. Epub 2009 Dec 23.

The Liggins Institute, The University of Auckland, New Zealand.

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http://dx.doi.org/10.1042/CS20090503DOI Listing
December 2009

Trefoil factor-1 (TFF1) enhances oncogenicity of mammary carcinoma cells.

Endocrinology 2009 Oct 9;150(10):4473-83. Epub 2009 Jul 9.

The Liggins Institute, University of Auckland, Private Bag 92019, Auckland, New Zealand.

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http://dx.doi.org/10.1210/en.2009-0066DOI Listing
October 2009

Epigenetic regulation of E-cadherin controls endometrial receptivity.

Endocrinology 2009 Mar 30;150(3):1466-72. Epub 2008 Oct 30.

Faculty of Medical and Health Sciences, National Research Centre for Growth, Development and the Liggins Institute, University of Auckland, Private Bag, Auckland, New Zealand.

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http://dx.doi.org/10.1210/en.2008-1142DOI Listing
March 2009

Autocrine human growth hormone promotes tumor angiogenesis in mammary carcinoma.

Endocrinology 2009 Mar 30;150(3):1341-52. Epub 2008 Oct 30.

Liggins Institute, University of Auckland, Private Bag, Auckland, New Zealand.

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http://dx.doi.org/10.1210/en.2008-0608DOI Listing
March 2009

Autocrine human growth hormone stimulates oncogenicity of endometrial carcinoma cells.

Endocrinology 2008 Aug 1;149(8):3909-19. Epub 2008 May 1.

Liggins Institute and National Research Centre for Growth and Development, University of Auckland, 2-6 Park Avenue, Private Bag 92019 Auckland, New Zealand.

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http://dx.doi.org/10.1210/en.2008-0286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488240PMC
August 2008

Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell.

Endocrinology 2008 May 14;149(5):2219-29. Epub 2008 Feb 14.

The Liggins Institute and National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1210/en.2007-1320DOI Listing
May 2008

Are trefoil factors oncogenic?

Trends Endocrinol Metab 2008 Mar 3;19(2):74-81. Epub 2007 Dec 3.

Liggins Institute, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1016/j.tem.2007.10.003DOI Listing
March 2008

The contribution of growth hormone to mammary neoplasia.

J Mammary Gland Biol Neoplasia 2008 Mar 7;13(1):131-45. Epub 2008 Feb 7.

The Liggins Institute, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland, New Zealand.

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http://dx.doi.org/10.1007/s10911-008-9070-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665193PMC
March 2008

AlphaCP1 mediates stabilization of hTERT mRNA by autocrine human growth hormone.

J Biol Chem 2007 Jan 3;282(1):680-90. Epub 2006 Nov 3.

Liggins Institute and the National Research Centre for Growth and Development, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1074/jbc.M600224200DOI Listing
January 2007

The oncogenic potential of growth hormone.

Growth Horm IGF Res 2006 Oct-Dec;16(5-6):277-89. Epub 2006 Nov 13.

The Liggins Institute and the National Research Centre for Growth and Development, University of Auckland, 2-6 Park Avenue, Grafton, Private Bag 92019, Auckland 1023, New Zealand.

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https://linkinghub.elsevier.com/retrieve/pii/S10966374060012
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http://dx.doi.org/10.1016/j.ghir.2006.09.006DOI Listing
January 2007