Peter E Clayton

Peter E Clayton

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Peter E Clayton

Peter E Clayton

Publications by authors named "Peter E Clayton"

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Retrospective review of Synacthen testing in infants.

Arch Dis Child 2018 10 12;103(10):984-986. Epub 2018 Jan 12.

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2017-313819DOI Listing
October 2018

A genetic approach to evaluation of short stature of undetermined cause.

Lancet Diabetes Endocrinol 2018 07 1;6(7):564-574. Epub 2018 Feb 1.

Diabetes and Endocrinology, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(18)30034-2DOI Listing
July 2018

Phenotypic spectrum and responses to recombinant human IGF1 (rhIGF1) therapy in patients with homozygous intronic pseudoexon growth hormone receptor mutation.

Eur J Endocrinol 2018 May 2;178(5):481-489. Epub 2018 Mar 2.

Centre for EndocrinologyWilliam Harvey Research Institute, Barts and the London School of Medicine & Dentistry, Queen Mary University of London, London, UK

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http://dx.doi.org/10.1530/EJE-18-0042DOI Listing
May 2018

Transcriptomics and machine learning predict diagnosis and severity of growth hormone deficiency.

JCI Insight 2018 04 5;3(7). Epub 2018 Apr 5.

Division of Developmental Biology and Medicine, Faculty of Biology, Medicine and Health, University of Manchester and Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://dx.doi.org/10.1172/jci.insight.93247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928867PMC
April 2018

Ghrelin and Growth.

Endocr Dev 2017 15;32:74-86. Epub 2017 Aug 15.

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http://dx.doi.org/10.1159/000475732DOI Listing
February 2018

Assessing the population impact of low rates of vitamin D supplementation on type 1 diabetes using a new statistical method.

JRSM Open 2016 Nov 1;7(11):2054270416653522. Epub 2016 Nov 1.

The University of Manchester, Manchester Academic Health Science Centre, Department of Paediatric Endocrinology, Central Manchester University Hospitals NHS Trust, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1177/2054270416653522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117162PMC
November 2016

Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability.

Am J Hum Genet 2016 Feb 28;98(2):363-72. Epub 2016 Jan 28.

Manchester Centre for Genomic Medicine, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester M13 9WL, UK; Manchester Centre for Genomic Medicine, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre (MAHSC), Manchester M13 9WL, UK. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(15)00509-1.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971500509
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http://dx.doi.org/10.1016/j.ajhg.2015.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746363PMC
February 2016

Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism.

Front Endocrinol (Lausanne) 2016 9;7. Epub 2016 Feb 9.

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, UK; Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.3389/fendo.2016.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747152PMC
February 2016

Identifying biological pathways that underlie primordial short stature using network analysis.

J Mol Endocrinol 2014 Jun 7;52(3):333-44. Epub 2014 Apr 7.

Institute of Human DevelopmentFaculty of Medical and Human Sciences, The University of Manchester, Oxford Road, Manchester M13 9WL, UKManchester Academic Health Sciences Centre (MAHSC)Central Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UKInstitute of Human DevelopmentFaculty of Medical and Human Sciences, The University of Manchester, Oxford Road, Manchester M13 9WL, UKManchester Academic Health Sciences Centre (MAHSC)Central Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1530/JME-14-0029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045235PMC
June 2014

Reduced Glycemic Variability in Diazoxide-Responsive Children with Congenital Hyperinsulinism Using Supplemental Omega-3-Polyunsaturated Fatty Acids; A Pilot Trial with MaxEPA(R.).

Front Endocrinol (Lausanne) 2014 12;5:31. Epub 2014 Mar 12.

Department of Paediatric Endocrinology, Manchester Academic Health Science Centre, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust , Manchester , UK ; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester , Manchester , UK.

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http://dx.doi.org/10.3389/fendo.2014.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952031PMC
March 2014

Metformin in the treatment of obese children and adolescents at risk of type 2 diabetes.

Paediatr Drugs 2014 Feb;16(1):13-20

Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital, Sharoe Green Lane, Preston, PR2 9HT, UK,

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http://dx.doi.org/10.1007/s40272-013-0045-1DOI Listing
February 2014

No evidence of an increase in early infant mortality from congenital adrenal hyperplasia in the absence of screening.

Arch Dis Child 2014 Feb 13;99(2):158-64. Epub 2013 Nov 13.

Department of Biochemistry, Central Manchester University Hospitals NHS Foundation Trust, UK.

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http://dx.doi.org/10.1136/archdischild-2013-304473DOI Listing
February 2014

The impact of malaria in pregnancy on changes in blood pressure in children during their first year of life.

Hypertension 2014 Jan 14;63(1):167-72. Epub 2013 Oct 14.

Cardiovascular Medicine Group, Division of Diabetes and Nutrition, 4th floor, Franklin-Wilkins Bldg, 150 Stamford St, King's College & King's Health Partners, London SE1 9RN, United Kingdom.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02238DOI Listing
January 2014

Endocrine control of growth.

Am J Med Genet C Semin Med Genet 2013 May;163C(2):76-85

National Institute Health Research (NIHR), University of Manchester and Royal Manchester Children' Hospital, Manchester, UK.

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http://dx.doi.org/10.1002/ajmg.c.31357DOI Listing
May 2013

Can network biology unravel the aetiology of congenital hyperinsulinism?

Orphanet J Rare Dis 2013 Feb 8;8:21. Epub 2013 Feb 8.

Department of Endocrinology, Royal Manchester Children's Hospital, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1186/1750-1172-8-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599136PMC
February 2013

Transition in endocrinology: the challenge of maintaining continuity.

Clin Endocrinol (Oxf) 2013 Jan;78(1):29-35

School of Nursing, Midwifery and Social Work, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2012.04473.xDOI Listing
January 2013

Exploring the spectrum of 3-M syndrome, a primordial short stature disorder of disrupted ubiquitination.

Clin Endocrinol (Oxf) 2012 Sep;77(3):335-42

Developmental Biomedicine, Manchester Academic Health Sciences Centre (MAHSC), School of Biomedicine, University of Manchester, UK.

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http://doi.wiley.com/10.1111/j.1365-2265.2012.04428.x
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http://dx.doi.org/10.1111/j.1365-2265.2012.04428.xDOI Listing
September 2012

The genetics of 3-M syndrome: unravelling a potential new regulatory growth pathway.

Horm Res Paediatr 2011 29;76(6):369-78. Epub 2011 Nov 29.

Department of Endocrinology, Manchester Biomedical Centre, Manchester Academic Health Sciences Centre, School of Biomedicine, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1159/000334392DOI Listing
April 2012

Maternal malaria status and metabolic profiles in pregnancy and in cord blood: relationships with birth size in Nigerian infants.

Malar J 2012 Mar 19;11:75. Epub 2012 Mar 19.

Manchester Academic Health Sciences Centre, University of Manchester, Paediatric Endocrinology, 5th Floor (Research), Royal Manchester Children's Hospital, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1186/1475-2875-11-75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325162PMC
March 2012

Predicting response to growth hormone treatment.

Indian J Pediatr 2012 Feb 22;79(2):229-37. Epub 2011 Nov 22.

Department of Pediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, M13 9WL, UK.

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http://dx.doi.org/10.1007/s12098-011-0611-xDOI Listing
February 2012

Reduced pericellular sensitivity to IGF-I in fibroblasts from girls with Turner syndrome: a mechanism to impair clinical responses to GH.

Pediatr Res 2011 Jul;70(1):25-30

Maternal and Fetal Health Research Centre, University of Manchester, St Mary's Hospital, Manchester M13 9WL, United Kingdom.

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http://dx.doi.org/10.1203/PDR.0b013e31821b570bDOI Listing
July 2011

Growth hormone, the insulin-like growth factor axis, insulin and cancer risk.

Nat Rev Endocrinol 2011 Jan 19;7(1):11-24. Epub 2010 Oct 19.

Manchester Academic Health Sciences Centre, University of Manchester, Paediatric Endocrinology, Royal Manchester Children's Hospital, Oxford Road, Manchester, UK.

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http://dx.doi.org/10.1038/nrendo.2010.171DOI Listing
January 2011

Diagnosis and management of primary insulin-like growth factor-I deficiency: current perspectives and clinical update.

Pediatr Endocrinol Rev 2010 Feb;7 Suppl 1:154-71

Cincinnati Children's Hospital Medical Center, OH, 45229-3039, USA.

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February 2010

A pilot study to evaluate gene expression profiles in peripheral blood mononuclear cells (PBMCs) from children with GH deficiency and Turner syndrome in response to GH treatment.

Clin Endocrinol (Oxf) 2009 Mar 8;70(3):429-34. Epub 2008 Nov 8.

Endocrine Sciences Research Group, University of Manchester, Oxford Road, Manchester, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2008.03477.xDOI Listing
March 2009

Association studies of common variants in 10 hypogonadotropic hypogonadism genes with age at menarche.

J Clin Endocrinol Metab 2008 Nov 26;93(11):4290-8. Epub 2008 Aug 26.

Program in Genomics and Division of Endocrinology, Children's Hospital, and Department of Genetics, Harvard Medical School, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1210/jc.2008-0981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582573PMC
November 2008

The relationship between nocturnal urinary leptin and gonadotrophins as children progress towards puberty.

Horm Res 2007 28;68(5):225-30. Epub 2007 Mar 28.

Endocrine Sciences Research Group, Division of Human Development, School of Medicine, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1159/000101335DOI Listing
November 2007

Exon splice enhancer mutation (GH-E32A) causes autosomal dominant growth hormone deficiency.

J Clin Endocrinol Metab 2007 Nov 28;92(11):4427-35. Epub 2007 Aug 28.

Department of Pediatric Endocrinology, Diabetology, and Metabolism, Inselspital, University Children's Hospital, CH-3010 Bern, Switzerland.

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http://dx.doi.org/10.1210/jc.2007-0857DOI Listing
November 2007

Growth hormone treatment and cancer risk.

Endocrinol Metab Clin North Am 2007 Mar;36(1):247-63

Department of Pediatric Endocrinology, Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Swinton, Manchester M27 4HA, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S088985290600098
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http://dx.doi.org/10.1016/j.ecl.2006.11.007DOI Listing
March 2007

The contributions of plasma IGF-I, IGFBP-3 and leptin to growth in extremely premature infants during the first two years.

Pediatr Res 2007 Jan;61(1):99-104

Academic Unit of Child Health, The University of Manchester, Manchester M9 7AA, UK.

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http://dx.doi.org/10.1203/01.pdr.0000250036.34522.f1DOI Listing
January 2007

Adiponectin in umbilical cord blood is inversely related to low-density lipoprotein cholesterol but not ethnicity.

J Clin Endocrinol Metab 2006 Jun 21;91(6):2244-9. Epub 2006 Mar 21.

Clinical Epidemiology Group, University of Manchester Medical School, Stopford Building, Oxford Road, Manchester, United Kingdom.

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http://dx.doi.org/10.1210/jc.2005-2714DOI Listing
June 2006

Clinical utility of insulin-like growth factor-I (IGF-I) and IGF binding protein-3 measurements in paediatric practice.

Pediatr Endocrinol Rev 2006 Jun;3(4):393-402

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, UK.

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June 2006

Geographical distribution of optic nerve hypoplasia and septo-optic dysplasia in Northwest England.

J Pediatr 2006 Jan;148(1):85-8

Academic Unit of Child Health, The University of Manchester, Booth Hall Children's Hospital, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.jpeds.2005.07.031DOI Listing
January 2006

Difficulties in patient management associated with the transition period.

Horm Res 2005 ;64 Suppl 2:74-5

Endocrine Science Research Group, Division of Human Development, The Medical School, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1159/000087759DOI Listing
December 2005

Novel mutations within the POU1F1 gene associated with variable combined pituitary hormone deficiency.

J Clin Endocrinol Metab 2005 Aug 31;90(8):4762-70. Epub 2005 May 31.

Biochemistry, Endocrinology, and Metabolism Unit and London Centre for Paediatric Endocrinology, Institute of Child Health, London, United Kingdom.

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http://dx.doi.org/10.1210/jc.2005-0570DOI Listing
August 2005

Determination of sequence variation and haplotype structure for the gonadotropin-releasing hormone (GnRH) and GnRH receptor genes: investigation of role in pubertal timing.

J Clin Endocrinol Metab 2005 Feb 16;90(2):1091-9. Epub 2004 Nov 16.

Division of Endocrinology and Genetics, Department of Medicine, Children's Hospital, Hravard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1210/jc.2004-0649DOI Listing
February 2005

Variability in anterior pituitary size within members of a family with GH deficiency due to a new splice mutation in the GHRH receptor gene.

Clin Endocrinol (Oxf) 2004 Apr;60(4):470-5

Division of Endocrinology, and The Ilyssa Center for Molecular and Cellular Endocrinology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1111/j.1365-2265.2004.02003.xDOI Listing
April 2004

Behavioral and physical masculinization are related to genotype in girls with congenital adrenal hyperplasia.

J Clin Endocrinol Metab 2004 Jan;89(1):419-24

Royal Manchester Children's Hospital, Manchester M27 4HA, United Kingdom.

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http://dx.doi.org/10.1210/jc.2003-030696DOI Listing
January 2004

European audit of current practice in diagnosis and treatment of childhood growth hormone deficiency.

Horm Res 2002 ;58(5):233-41

Department of Growth and Reproduction, National University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1159/000066265DOI Listing
May 2003

A new missense mutation in the growth hormone-releasing hormone receptor gene in familial isolated GH deficiency.

Eur J Endocrinol 2003 Jan;148(1):25-30

Divisions of Pediatric Endocrinology and Endocrinology and The Ilyssa Center for Molecular and Cellular Endocrinology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1530/eje.0.1480025DOI Listing
January 2003

Growth hormone signal transduction and possible defects in children.

J Pediatr Endocrinol Metab 2002 Dec;15 Suppl 5:1451-2

Endocrine Science Research Group, Academic Unit of Human Development & Reproductive Health, University of Manchester, Manchester, UK.

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December 2002

Diagnosis and management of growth hormone deficiency in childhood and adolescence--part 2: growth hormone treatment in growth hormone deficient children.

Growth Horm IGF Res 2002 Oct;12(5):323-41

Department of Endocrinology and Metabolism, National Children's Medical Research Center, Tokyo, Japan.

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http://dx.doi.org/10.1016/s1096-6374(02)00045-xDOI Listing
October 2002

Serum leptin and IGF-I during growth hormone treatment in chronic renal failure.

Pediatr Nephrol 2002 Aug 11;17(8):643-7. Epub 2002 Jun 11.

Department of Child Health, University of Manchester, Manchester M9 7AA, UK.

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http://dx.doi.org/10.1007/s00467-002-0883-5DOI Listing
August 2002

GH and epidermal growth factor signaling in normal and Laron syndrome fibroblasts.

Endocrinology 2002 Jul;143(7):2610-7

Department of Internal Medicine, Division of Endocrinology, University of Virginia, Charlottesville 22908, USA.

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http://dx.doi.org/10.1210/endo.143.7.8909DOI Listing
July 2002

Is final height the only target of paediatric human growth hormone treatment?

Authors:
Peter E Clayton

Int J Clin Pract Suppl 2002 May(126):3-7

University of Manchester, UK.

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May 2002