Publications by authors named "Peter Drueckes"

20Publications

Promiscuity analysis of a kinase panel screen with designated p38 alpha inhibitors.

Eur J Med Chem 2020 Feb 20;187:112004. Epub 2019 Dec 20.

Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Endenicher Allee 19c, D-53115, Bonn, Germany. Electronic address:

View Article and Find Full Text PDF
February 2020

Protein Kinase Selectivity Profiling Using Microfluid Mobility Shift Assays.

Authors:
Peter Drueckes

Methods Mol Biol 2016 ;1439:143-57

CPC Screening Sciences, Novartis Pharma AG, Novartis Institutes for Biomedical Research, 4002, Basel, Switzerland.

View Article and Find Full Text PDF
December 2017

Type II Inhibitors Targeting CDK2.

ACS Chem Biol 2015 Sep 20;10(9):2116-25. Epub 2015 Jul 20.

Structural Genomics Consortium, University of Oxford , Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, United Kingdom.

View Article and Find Full Text PDF
September 2015

Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers.

Clin Cancer Res 2014 Apr 28;20(7):1834-45. Epub 2014 Jan 28.

Authors' Affiliations: Oncology Disease Area Research; Global Discovery Chemistry/Oncology and Exploratory Chemistry; MAP Group; Chemical and Pharmaceutical Profiling Group, Novartis Institutes for Biomedical Research, Emeryville, California; Developmental Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts; Oncology Disease Area Research; and Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, Basel, Switzerland.

View Article and Find Full Text PDF
April 2014

Substrate profiling of IGF-1R and InsR: identification of a potent pentamer substrate.

Bioorg Med Chem Lett 2011 Dec 29;21(23):7030-3. Epub 2011 Sep 29.

Novartis Institutes for BioMedical Research, Basel, Switzerland.

View Article and Find Full Text PDF
December 2011

Kinase inhibition by deoxy analogues of the resorcylic lactone L-783277.

ACS Med Chem Lett 2011 Jan 20;2(1):22-7. Epub 2010 Oct 20.

Swiss Federal Institute of Technology (ETH) Zurich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, 8093 Zurich, Switzerland.

View Article and Find Full Text PDF
January 2011