Peter D Paré

Peter D Paré

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Peter D Paré

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The Huxley crossbridge model as the basic mechanism for airway smooth muscle contraction.

Am J Physiol Lung Cell Mol Physiol 2019 Aug 22;317(2):L235-L246. Epub 2019 May 22.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/ajplung.00051.2019DOI Listing
August 2019

Genome-wide interaction study of gene-by-occupational exposures on respiratory symptoms.

Environ Int 2019 01 16;122:263-269. Epub 2018 Nov 16.

University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01604120183128
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http://dx.doi.org/10.1016/j.envint.2018.11.017DOI Listing
January 2019

Small airways disease in mild and moderate chronic obstructive pulmonary disease: a cross-sectional study.

Lancet Respir Med 2018 08 4;6(8):591-602. Epub 2018 Jul 4.

Centre for Heart Lung Innovation, University of British Columbia, St Paul's Hospital, Vancouver, BC, Canada; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132600183019
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http://dx.doi.org/10.1016/S2213-2600(18)30196-6DOI Listing
August 2018

The genetics of smoking in individuals with chronic obstructive pulmonary disease.

Respir Res 2018 04 10;19(1):59. Epub 2018 Apr 10.

The University of British Columbia Center for Heart Lung Innovation, St Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1186/s12931-018-0762-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892035PMC
April 2018

Smooth muscle function and myosin polymerization.

J Cell Sci 2017 Aug 8;130(15):2468-2480. Epub 2017 Jun 8.

Centre for Heart Lung Innovation - St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada, V6Z 1Y6

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http://dx.doi.org/10.1242/jcs.202812DOI Listing
August 2017

Hyperresponsiveness: Relating the Intact Airway to the Whole Lung.

Physiology (Bethesda) 2017 07;32(4):322-331

Centre for Heart Lung Innovation-St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada; and.

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http://dx.doi.org/10.1152/physiol.00008.2017DOI Listing
July 2017

Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease.

EBioMedicine 2017 May 12;19:139-145. Epub 2017 Apr 12.

UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada; Department of Medicine (Pulmonary Division), University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440622PMC
May 2017

The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease.

Physiol Rev 2017 04;97(2):529-552

Centre for Heart Lung Innovation, St Paul's Hospital, University of British Columbia (UBC), British Columbia, Canada; Department of Pathology and Laboratory Medicine, UBC, British Columbia, Canada; Respiratory Division, Department of Medicine, UBC, British Columbia, Canada; and Department of Anesthesiology, Pharmacology and Therapeutics, UBC, British Columbia, Canada.

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http://dx.doi.org/10.1152/physrev.00025.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151481PMC
April 2017

Identification of Susceptibility Genes of Adult Asthma in French Canadian Women.

Can Respir J 2016 4;2016:3564341. Epub 2016 May 4.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec City, QC, Canada G1V 4G5; Department of Molecular Medicine, Laval University, Quebec City, QC, Canada G1V 0A6.

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http://dx.doi.org/10.1155/2016/3564341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904514PMC
March 2017

Micro-Computed Tomography Comparison of Preterminal Bronchioles in Centrilobular and Panlobular Emphysema.

Am J Respir Crit Care Med 2017 03;195(5):630-638

1 Centre for Heart and Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1164/rccm.201602-0278OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363975PMC
March 2017

Airway smooth muscle tone increases airway responsiveness in healthy young adults.

Am J Physiol Lung Cell Mol Physiol 2017 Mar 9;312(3):L348-L357. Epub 2016 Dec 9.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada;

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http://dx.doi.org/10.1152/ajplung.00400.2016DOI Listing
March 2017

Heterogeneity of airway wall dimensions in humans: a critical determinant of lung function in asthmatics and nonasthmatics.

Am J Physiol Lung Cell Mol Physiol 2017 Mar 6;312(3):L425-L431. Epub 2017 Jan 6.

Department of Mathematics, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1152/ajplung.00421.2016DOI Listing
March 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326681PMC
March 2017

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Nat Genet 2017 Mar 6;49(3):426-432. Epub 2017 Feb 6.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381275PMC
March 2017

Bronchodilatory effect of deep inspiration in freshly isolated sheep lungs.

Am J Physiol Lung Cell Mol Physiol 2017 02 2;312(2):L178-L185. Epub 2016 Dec 2.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada; and

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http://dx.doi.org/10.1152/ajplung.00321.2016DOI Listing
February 2017

Associations of interleukin-1 gene cluster polymorphisms with C-reactive protein concentration and lung function decline in smoking-induced chronic obstructive pulmonary disease.

Int J Clin Exp Pathol 2015 1;8(10):13125-35. Epub 2015 Oct 1.

Department of Respiratory and Critical Medicine, West China Hospital of Sichuan University Chengdu, Sichuan Province, China ; Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital Vancouver, BC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680456PMC
October 2016

The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease.

Nicotine Tob Res 2016 09 6;18(9):1903-9. Epub 2016 May 6.

University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, BC, Canada; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada

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http://dx.doi.org/10.1093/ntr/ntw129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978988PMC
September 2016

Susceptibility genes for lung diseases in the major histocompatibility complex revealed by lung expression quantitative trait loci analysis.

Eur Respir J 2016 08 12;48(2):573-6. Epub 2016 May 12.

Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, Canada Dept of Molecular Medicine, Laval University, Québec, QC, Canada

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http://dx.doi.org/10.1183/13993003.00114-2016DOI Listing
August 2016

The Effect of Statins on Blood Gene Expression in COPD.

PLoS One 2015 13;10(10):e0140022. Epub 2015 Oct 13.

The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, BC, Canada; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140022PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604084PMC
June 2016

Behavioral Changes in General Practitioners towards Chronic Obstructive Pulmonary Disease Over Five Years: An Observational Study.

Intern Med 2015 15;54(14):1705-10. Epub 2015 Jul 15.

Division of Respiratory Medicine, Department of Internal Medicine, Shiga University of Medical Science, Japan.

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http://dx.doi.org/10.2169/internalmedicine.54.4170DOI Listing
March 2016

Vitronectin expression in the airways of subjects with asthma and chronic obstructive pulmonary disease.

PLoS One 2015 13;10(3):e0119717. Epub 2015 Mar 13.

School of Medicine, Universidad CES, Medellín, Colombia; James Hogg Research Centre, University of British Columbia, Vancouver, BC, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119717PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358944PMC
February 2016

Airway Epithelial Expression Quantitative Trait Loci Reveal Genes Underlying Asthma and Other Airway Diseases.

Am J Respir Cell Mol Biol 2016 Feb;54(2):177-87

2 Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1165/rcmb.2014-0381OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821039PMC
February 2016

Biphasic force response to iso-velocity stretch in airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2015 Oct 7;309(7):L653-61. Epub 2015 Aug 7.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada; and Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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http://dx.doi.org/10.1152/ajplung.00201.2015DOI Listing
October 2015

Development and maintenance of force and stiffness in airway smooth muscle.

Can J Physiol Pharmacol 2015 Mar 17;93(3):163-9. Epub 2014 Dec 17.

Bioengineering College, Chongqing University, Chongqing, China., Centre for Heart and Lung Innovation, St Paul's Hospital and University of British Columbia, 1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada.

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http://dx.doi.org/10.1139/cjpp-2014-0404DOI Listing
March 2015

The importance of complete tissue homogenization for accurate stoichiometric measurement of myosin light chain phosphorylation in airway smooth muscle.

Can J Physiol Pharmacol 2015 Feb 19;93(2):155-62. Epub 2014 Nov 19.

a Respiratory Division, Department of Medicine, Vancouver, BC V5Z 1M9, Canada.

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http://dx.doi.org/10.1139/cjpp-2014-0357DOI Listing
February 2015

Gene expression in asthmatic airway smooth muscle: a mixed bag.

Can J Physiol Pharmacol 2015 Feb 8;93(2):137-43. Epub 2014 Dec 8.

a Department of Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.

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http://dx.doi.org/10.1139/cjpp-2014-0390DOI Listing
February 2015

Force maintenance and myosin filament assembly regulated by Rho-kinase in airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2015 Jan 10;308(1):L1-10. Epub 2014 Oct 10.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada; Centre for Heart Lung Innovation, St Paul's Hospital, University of British Columbia, Vancouver, Canada

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http://dx.doi.org/10.1152/ajplung.00222.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281697PMC
January 2015

Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung.

Carcinogenesis 2014 Dec 3;35(12):2653-9. Epub 2014 Sep 3.

Institut universitaire de cardiologie et de pneumologie de Québec, Québec G1V 4G5, Canada, Department of Molecular Medicine, Laval University, Québec G1V 0A6, Canada

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http://dx.doi.org/10.1093/carcin/bgu184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247514PMC
December 2014

Bronchoprotective effect of simulated deep inspirations in tracheal smooth muscle.

J Appl Physiol (1985) 2014 Dec 16;117(12):1502-13. Epub 2014 Oct 16.

Department of Medicine, Respiratory Division, University of British Columbia, Vancouver, British Columbia, Canada; Center for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/japplphysiol.00713.2014DOI Listing
December 2014

Wheezing in young children: WAITing for pharmacogenomics?

Lancet Respir Med 2014 Oct 16;2(10):776-7. Epub 2014 Sep 16.

University of British Columbia Center for Heart Lung Innovation, St Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/S2213-2600(14)70189-4DOI Listing
October 2014

Lung expression quantitative trait loci data set identifies important functional polymorphisms in the asthma-associated IL1RL1 region.

J Allergy Clin Immunol 2014 Sep 18;134(3):729-31. Epub 2014 Apr 18.

UBC James Hogg Research Centre, Heart + Lung Institute, St Paul's Hospital, Vancouver, British Columbia, Canada; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.jaci.2014.02.039DOI Listing
September 2014

From the authors.

Eur Respir J 2014 Jul;44(1):262-3

James Hogg Research Center, University of British Columbia, Vancouver, BC Dept of Radiology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1183/09031936.00029614DOI Listing
July 2014

COPD phenotypes in biomass smoke- versus tobacco smoke-exposed Mexican women.

Eur Respir J 2014 Mar 10;43(3):725-34. Epub 2013 Oct 10.

University of British Columbia, St Paul's Hospital, Vancouver, BC.

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http://dx.doi.org/10.1183/09031936.00206112DOI Listing
March 2014

Alveolar macrophage proteinase/antiproteinase expression in lung function and emphysema.

Eur Respir J 2014 Jan 30;43(1):82-91. Epub 2013 Jul 30.

Institute for Heart and Lung Health, St. Paul's Hospital, Vancouver, BC.

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http://dx.doi.org/10.1183/09031936.00174612DOI Listing
January 2014

Myosin filaments in smooth muscle cells do not have a constant length.

J Physiol 2013 Dec 30;591(23):5867-78. Epub 2013 Sep 30.

C. Y. Seow: James Hogg Research Centre, St Paul's Hospital, 1081 Burrard Street, Vancouver, BC, Canada, V6Z 1Y6.

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http://dx.doi.org/10.1113/jphysiol.2013.264168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872758PMC
December 2013

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.

Authors:
Sarah H Stephens Sarah M Hartz Nicole R Hoft Nancy L Saccone Robin C Corley John K Hewitt Christian J Hopfer Naomi Breslau Hilary Coon Xiangning Chen Francesca Ducci Nicole Dueker Nora Franceschini Josef Frank Younghun Han Nadia N Hansel Chenhui Jiang Tellervo Korhonen Penelope A Lind Jason Liu Leo-Pekka Lyytikäinen Martha Michel John R Shaffer Susan E Short Juzhong Sun Alexander Teumer John R Thompson Nicole Vogelzangs Jacqueline M Vink Angela Wenzlaff William Wheeler Bao-Zhu Yang Steven H Aggen Anthony J Balmforth Sebastian E Baumeister Terri H Beaty Daniel J Benjamin Andrew W Bergen Ulla Broms David Cesarini Nilanjan Chatterjee Jingchun Chen Yu-Ching Cheng Sven Cichon David Couper Francesco Cucca Danielle Dick Tatiana Foroud Helena Furberg Ina Giegling Nathan A Gillespie Fangyi Gu Alistair S Hall Jenni Hällfors Shizhong Han Annette M Hartmann Kauko Heikkilä Ian B Hickie Jouke Jan Hottenga Pekka Jousilahti Marika Kaakinen Mika Kähönen Philipp D Koellinger Stephen Kittner Bettina Konte Maria-Teresa Landi Tiina Laatikainen Mark Leppert Steven M Levy Rasika A Mathias Daniel W McNeil Sarah E Medland Grant W Montgomery Tanda Murray Matthias Nauck Kari E North Peter D Paré Michele Pergadia Ingo Ruczinski Veikko Salomaa Jorma Viikari Gonneke Willemsen Kathleen C Barnes Eric Boerwinkle Dorret I Boomsma Neil Caporaso Howard J Edenberg Clyde Francks Joel Gelernter Hans Jörgen Grabe Hyman Hops Marjo-Riitta Jarvelin Magnus Johannesson Kenneth S Kendler Terho Lehtimäki Patrik K E Magnusson Mary L Marazita Jonathan Marchini Braxton D Mitchell Markus M Nöthen Brenda W Penninx Olli Raitakari Marcella Rietschel Dan Rujescu Nilesh J Samani Ann G Schwartz Sanjay Shete Margaret Spitz Gary E Swan Henry Völzke Juha Veijola Qingyi Wei Chris Amos Dale S Cannon Richard Grucza Dorothy Hatsukami Andrew Heath Eric O Johnson Jaakko Kaprio Pamela Madden Nicholas G Martin Victoria L Stevens Robert B Weiss Peter Kraft Laura J Bierut Marissa A Ehringer

Genet Epidemiol 2013 Dec 1;37(8):846-59. Epub 2013 Nov 1.

Department of Epidemiology and Public Health, University of Maryland, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1002/gepi.21760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947535PMC
December 2013

Does the length dependency of airway smooth muscle force contribute to airway hyperresponsiveness?

J Appl Physiol (1985) 2013 Nov 22;115(9):1304-15. Epub 2013 Aug 22.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Department of Medicine, Université Laval, Québec City, Québec, Canada;

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http://dx.doi.org/10.1152/japplphysiol.01480.2012DOI Listing
November 2013

DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children.

PLoS One 2012 6;7(9):e44213. Epub 2012 Sep 6.

Department of Medicine, James Hogg Research Centre at the Heart and Lung Institute, University of British Columbia and St Paul's Hospital, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044213PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435400PMC
May 2013

Genetic testing for respiratory disease: are we there yet?

Authors:
Peter D Paré

Can Respir J 2012 Jul-Aug;19(4):246-8

University of British Columbia, James Hoog Research Centre, St. Paul's Hospital, Vancouver, British Columbia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411388PMC
http://dx.doi.org/10.1155/2012/212658DOI Listing
April 2013

Decrease of airway smooth muscle contractility induced by simulated breathing maneuvers is not simply proportional to strain.

J Appl Physiol (1985) 2013 Feb 29;114(3):335-43. Epub 2012 Nov 29.

University of British Columbia, James Hogg Research Center, St. Paul's Hospital Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/japplphysiol.00870.2012DOI Listing
February 2013

Counterpoint: alterations in airway smooth muscle phenotype do not cause airway hyperresponsiveness in asthma.

J Appl Physiol (1985) 2012 Sep;113(5):839-42

Department of Laboratory Medicine and Pathology University of British Columbia.

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http://dx.doi.org/10.1152/japplphysiol.00483.2012aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596735PMC
September 2012

Airway imaging in disease: gimmick or useful tool?

J Appl Physiol (1985) 2012 Aug 17;113(4):636-46. Epub 2012 May 17.

University of British Columbia James Hogg Research Centre and Institute for Heart + Lung Health, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/japplphysiol.00372.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424064PMC
August 2012

NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease.

Physiol Genomics 2012 Aug 12;44(15):754-63. Epub 2012 Jun 12.

UBC James Hogg Research Centre, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/physiolgenomics.00027.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774584PMC
August 2012

Mechanical properties of asthmatic airway smooth muscle.

Eur Respir J 2012 Jul 20;40(1):45-54. Epub 2012 Jan 20.

Dept of Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1183/09031936.00065411DOI Listing
July 2012

Force oscillations simulating breathing maneuvers do not prevent force adaptation.

Am J Respir Cell Mol Biol 2012 Jul 9;47(1):44-9. Epub 2012 Feb 9.

University of British Columbia, James Hogg Research Center, St. Paul’s Hospital Vancouver, Canada.

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http://dx.doi.org/10.1165/rcmb.2011-0429OCDOI Listing
July 2012

Airway-parenchymal interdependence.

Compr Physiol 2012 Jul;2(3):1921-35

University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/cphy.c110039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557883PMC
July 2012

Phenotyping COPD using high resolution CT. Is it time to leave it for Watson?

COPD 2012 Apr 12;9(2):87-9. Epub 2012 Mar 12.

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http://dx.doi.org/10.3109/15412555.2012.663980DOI Listing
April 2012

Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment?

J Appl Physiol (1985) 2012 Feb 13;112(3):337-46. Epub 2011 Oct 13.

James Hogg Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.

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http://www.physiology.org/doi/10.1152/japplphysiol.01036.201
Publisher Site
http://dx.doi.org/10.1152/japplphysiol.01036.2011DOI Listing
February 2012

A 'Good' muscle in a 'Bad' environment: the importance of airway smooth muscle force adaptation to airway hyperresponsiveness.

Respir Physiol Neurobiol 2011 Dec 14;179(2-3):269-75. Epub 2011 Sep 14.

The James Hogg Research Center, Providence Health Care/St. Paul's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.resp.2011.09.003DOI Listing
December 2011

Effect of gene environment interactions on lung function and cardiovascular disease in COPD.

Int J Chron Obstruct Pulmon Dis 2011 10;6:277-87. Epub 2011 May 10.

University of British Columbia, James Hogg Research Laboratories, St Paul's Hospital, Division of Respirology, Department of Medicine, Vancouver, BC, Canada.

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http://dx.doi.org/10.2147/COPD.S18279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144847PMC
November 2011

Time course of isotonic shortening and the underlying contraction mechanism in airway smooth muscle.

J Appl Physiol (1985) 2011 Sep 2;111(3):642-56. Epub 2011 Jun 2.

James Hogg Research Centre/St. Paul's Hospital, Univ. of British Columbia, 1081 Burrard St., Rm. 166, Vancouver, BC, Canada.

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http://dx.doi.org/10.1152/japplphysiol.00085.2011DOI Listing
September 2011

Effect of heme oxygenase-1 polymorphisms on lung function and gene expression.

BMC Med Genet 2011 Sep 8;12:117. Epub 2011 Sep 8.

UBC James Hogg Research Center, Providence Heart + Lung Institute, St, Paul's Hospital, Vancouver, B.C., Canada.

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http://dx.doi.org/10.1186/1471-2350-12-117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180266PMC
September 2011

Central airway compliance in asthma: up or down? Good or bad?

Authors:
Peter D Paré

Am J Respir Crit Care Med 2011 Mar;183(5):563-4

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http://dx.doi.org/10.1164/rccm.201009-1533EDDOI Listing
March 2011

Length oscillation mimicking periodic individual deep inspirations during tidal breathing attenuates force recovery and adaptation in airway smooth muscle.

J Appl Physiol (1985) 2010 Nov 9;109(5):1476-82. Epub 2010 Sep 9.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/japplphysiol.00676.2010DOI Listing
November 2010

Quantification of lung surface area using computed tomography.

Respir Res 2010 Oct 31;11:153. Epub 2010 Oct 31.

University of British Columbia James Hogg Research Centre and the Heart and Lung Institute, St. Paul’s Hospital, Burrard Street, Vancouver, Canada.

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http://dx.doi.org/10.1186/1465-9921-11-153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976969PMC
October 2010