Peter Calverley

Peter Calverley

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Peter Calverley

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The Pressing Need to Redefine "COPD".

Chronic Obstr Pulm Dis 2019 Nov;6(5):380-383

Pulmonary and Rehabilitation Research Group, University Hospital Aintree, Liverpool, United Kingdom.

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http://dx.doi.org/10.15326/jcopdf.6.5.2019.0173DOI Listing
November 2019

Genetics, Chronic Obstructive Pulmonary Disease, and the Arrow of Time.

Am J Respir Crit Care Med 2019 Sep;200(6):654-655

Institute of Ageing and Chronic DiseaseUniversity of LiverpoolLiverpool, United Kingdomand.

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http://dx.doi.org/10.1164/rccm.201904-0813EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775883PMC
September 2019

Regional differences in rate of FEV decline in COPD: lessons from SUMMIT.

Eur Respir J 2019 Jun 27;53(6). Epub 2019 Jun 27.

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, University of Manchester, and Manchester University NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK.

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http://dx.doi.org/10.1183/13993003.00278-2019DOI Listing
June 2019

Serum biomarkers and outcomes in patients with moderate COPD: a substudy of the randomised SUMMIT trial.

BMJ Open Respir Res 2019 4;6(1):e000431. Epub 2019 May 4.

Division of Infection, Immunity and Respiratory Medicine and Allergy, Manchester Academic Health Science Centre, The University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1136/bmjresp-2019-000431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561388PMC
May 2019

Lung Function through the PRISm. Spreading Light or Creating Confusion?

Am J Respir Crit Care Med 2018 12;198(11):1358-1360

3 Academy of Medical Sciences University of Liverpool Liverpool, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201806-1163EDDOI Listing
December 2018

Treatment of exacerbations as a predictor of subsequent outcomes in patients with COPD.

Int J Chron Obstruct Pulmon Dis 2018;13:1297-1308. Epub 2018 Apr 23.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.2147/COPD.S153631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922419PMC
October 2018

Safety of tiotropium/olodaterol in chronic obstructive pulmonary disease: pooled analysis of three large, 52-week, randomized clinical trials.

Respir Med 2018 10 28;143:67-73. Epub 2018 Aug 28.

Clinical Science Centre, Institute of Ageing and Chronic Disease, University of Liverpool, 6 West Derby Street, Liverpool, L7 8TX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2018.08.012DOI Listing
October 2018

Seasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR trial.

Int J Chron Obstruct Pulmon Dis 2018 14;13:605-616. Epub 2018 Feb 14.

Department of Pulmonary Diseases and Critical Care Medicine, University of Texas Health Science Center and South Texas Veterans Health Care System, San Antonio, TX, USA.

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http://dx.doi.org/10.2147/COPD.S148393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819585PMC
September 2018

Use of a 4-week up-titration regimen of roflumilast in patients with severe COPD.

Int J Chron Obstruct Pulmon Dis 2018 6;13:813-822. Epub 2018 Mar 6.

Department of Clinical Sciences, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.2147/COPD.S154012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846760PMC
September 2018

Determinants of exacerbation risk in patients with COPD in the TIOSPIR study.

Int J Chron Obstruct Pulmon Dis 2017 29;12:3391-3405. Epub 2017 Nov 29.

Pulmonary Medicine and Critical Care, University of Texas Health Sciences Center and South Texas Veterans' Health Care System, San Antonio, TX, USA.

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http://dx.doi.org/10.2147/COPD.S145814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713692PMC
August 2018

The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials.

Int J Chron Obstruct Pulmon Dis 2017 15;12:1457-1468. Epub 2017 May 15.

Department of Pulmonary Medicine and Tuberculosis, University Medical Center Groningen, GRIAC Research Institute, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.2147/COPD.S130713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440002PMC
March 2018

Reply: Chronic Obstructive Pulmonary Disease: Defining the Indefinable.

Authors:
Peter Calverley

Ann Am Thorac Soc 2018 03;15(3):390-391

1 University of Liverpool Liverpool, United Kingdom.

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http://dx.doi.org/10.1513/AnnalsATS.201711-902LEDOI Listing
March 2018

Pulmonary rehabilitation for patients with COPD during and after an exacerbation-related hospitalisation: back to the future?

Eur Respir J 2018 01 11;51(1). Epub 2018 Jan 11.

Airways Disease Section, National Heart and Lung Institute, Imperial College London, UK; co-chair, representing the European Respiratory Society.

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http://dx.doi.org/10.1183/13993003.02577-2017DOI Listing
January 2018

Cigarette smoking and response to inhaled corticosteroids in COPD.

Eur Respir J 2018 01 18;51(1). Epub 2018 Jan 18.

Division of Pulmonary, Allergy and Critical Care Medicine and Lung Health Center, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1183/13993003.01393-2017DOI Listing
January 2018

Triple Therapy in COPD: What We Know and What We Don't.

COPD 2017 Dec 9;14(6):648-662. Epub 2017 Nov 9.

d Airways Disease Section , National Heart and Lung Institute, Imperial College London , London , UK.

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http://dx.doi.org/10.1080/15412555.2017.1389875DOI Listing
December 2017

Where to start when treating COPD?

Respirology 2017 10 16;22(7):1239-1240. Epub 2017 Jul 16.

Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/resp.13126DOI Listing
October 2017

Breathlessness despite optimal pathophysiological treatment: on the relevance of being chronic.

Eur Respir J 2017 09 27;50(3). Epub 2017 Sep 27.

Clinical Science, University Hospital Aintree, Liverpool, UK

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http://dx.doi.org/10.1183/13993003.01376-2017DOI Listing
September 2017

Early efficacy of budesonide/formoterol in patients with moderate-to-very-severe COPD.

Int J Chron Obstruct Pulmon Dis 2017 19;12:13-25. Epub 2016 Dec 19.

Department of Pulmonary Medicine and Tuberculosis, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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https://www.dovepress.com/early--efficacy-of-budesonideformo
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http://dx.doi.org/10.2147/COPD.S114209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182036PMC
August 2017

Effect of roflumilast in patients with severe COPD and a history of hospitalisation.

Eur Respir J 2017 07 5;50(1). Epub 2017 Jul 5.

University of Modena and Reggio Emilia, Modena, Italy.

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http://dx.doi.org/10.1183/13993003.00158-2017DOI Listing
July 2017

AJRCCM: 100-Year Anniversary. Physiology and Chronic Obstructive Pulmonary Disease in the Blue Journals.

Am J Respir Crit Care Med 2017 May;195(9):1088-1090

1 Institute of Ageing and Chronic Disease University of Liverpool Liverpool, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201701-0114EDDOI Listing
May 2017

A Light in the Darkness? The FLAME Trial, Blood Eosinophils, and Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2017 05;195(9):1125-1127

1 Institute of Ageing and Chronic Disease University of Liverpool Liverpool, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201703-0560EDDOI Listing
May 2017

Chronic breathlessness: symptom or syndrome?

Eur Respir J 2017 05 25;49(5). Epub 2017 May 25.

School of Ageing and Chronic Disease, University Hospital Aintree, Liverpool, UK

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http://dx.doi.org/10.1183/13993003.00366-2017DOI Listing
May 2017

Chronic Obstructive Pulmonary Disease Exacerbations and Lung Function Decline. Mechanism or Marker?

Am J Respir Crit Care Med 2017 02;195(3):278-279

1 Institute of Ageing and Chronic Disease University of Liverpool Liverpool, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201609-1837EDDOI Listing
February 2017

Through a glass darkly: inhaled corticosteroids, airway inflammation and COPD.

Eur Respir J 2017 01 3;49(1). Epub 2017 Jan 3.

Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK

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http://dx.doi.org/10.1183/13993003.02201-2016DOI Listing
January 2017

Roflumilast: a review of its use in the treatment of COPD.

Int J Chron Obstruct Pulmon Dis 2016 6;11:81-90. Epub 2016 Jan 6.

Department of Internal Medicine, Christian-Albrechts University, Kiel, Germany; Department of Pulmonary Medicine and Medical Director, LungenClinic Grosshansdorf, Airway Research Centre North, German Centre for Lung Research, Grosshansdorf, Germany.

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http://dx.doi.org/10.2147/COPD.S89849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708192PMC
October 2016

Differences in outcomes between GOLD groups in patients with COPD in the TIOSPIR(®) trial.

Int J Chron Obstruct Pulmon Dis 2016 20;11:133-45. Epub 2016 Jan 20.

Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.2147/COPD.S97924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725639PMC
October 2016

Early response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations.

Int J Chron Obstruct Pulmon Dis 2016 25;11:381-90. Epub 2016 Feb 25.

George Institute for Global Health, Concord Clincal School, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.2147/COPD.S93303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772946PMC
October 2016

Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study.

Respir Med 2016 10 25;119:87-95. Epub 2016 Aug 25.

Department of Research and Education, CIRO+, Centre of Expertise for Chronic Organ Failure, Horn, The Netherlands; REVAL - Rehabilitation Research Center, BIOMED - Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2016.08.023DOI Listing
October 2016

COPD therapy: if two is good, is three better?

Lancet 2016 Sep 1;388(10048):937-8. Epub 2016 Sep 1.

School of Ageing and Chronic Disease, University of Liverpool, Liverpool L69 3BX, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(16)31464-7DOI Listing
September 2016

Tiotropium safety in 'real-world' populations: Response to Schmiedl, et al. in the British Journal of Clinical Pharmacology.

Br J Clin Pharmacol 2016 08 19;82(2):562-3. Epub 2016 May 19.

Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/bcp.12972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972173PMC
August 2016

A rational approach to single, dual and triple therapy in COPD.

Respirology 2016 May 26;21(4):581-9. Epub 2015 Nov 26.

Aintree Chest Centre, University Hospital Aintree, Liverpool, UK.

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http://dx.doi.org/10.1111/resp.12690DOI Listing
May 2016

Blood eosinophils as a marker of response to inhaled corticosteroids in COPD.

Eur Respir J 2016 05 25;47(5):1374-82. Epub 2016 Feb 25.

Respiratory Research Dept, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1183/13993003.01370-2015DOI Listing
May 2016

Tiotropium Respimat(®) Versus HandiHaler(®): Comparison of Bronchodilator Efficacy of Various Doses in Clinical Trials.

Adv Ther 2016 05 28;33(5):786-93. Epub 2016 Mar 28.

Clinical Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany.

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http://dx.doi.org/10.1007/s12325-016-0322-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882367PMC
May 2016

Lung function changes over time following withdrawal of inhaled corticosteroids in patients with severe COPD.

Eur Respir J 2016 Feb 19;47(2):651-4. Epub 2015 Nov 19.

Institute of Ageing and Chronic Disease, Aintree University Hospital, Liverpool, UK.

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http://dx.doi.org/10.1183/13993003.01644-2015DOI Listing
February 2016

Safety and efficacy of tiotropium in patients switching from HandiHaler to Respimat in the TIOSPIR trial.

BMJ Open 2015 Dec 29;5(12):e009015. Epub 2015 Dec 29.

Department of Pneumology, Hôpital Cochin, AP-HP, Université Paris Descartes, Paris, France.

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http://dx.doi.org/10.1136/bmjopen-2015-009015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710815PMC
December 2015

The Association Between Heroin Inhalation and Early Onset Emphysema.

Chest 2015 Nov;148(5):1156-1163

University Hospital Aintree, Liverpool, England.

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http://dx.doi.org/10.1378/chest.15-0236DOI Listing
November 2015

Continuous fat-free mass decline in COPD: fact or fiction?

Eur Respir J 2015 Nov 17;46(5):1496-8. Epub 2015 Sep 17.

Dept of Research and Education, CIRO, Horn, The Netherlands Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1183/13993003.00692-2015DOI Listing
November 2015

Knowing when to stop: inhaled corticosteroids and COPD.

Authors:
Peter Calverley

Eur Respir J 2015 Nov;46(5):1236-8

Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK

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http://dx.doi.org/10.1183/13993003.01372-2015DOI Listing
November 2015

Safety and efficacy of tiotropium Respimat versus HandiHaler in patients naive to treatment with inhaled anticholinergics: a post hoc analysis of the TIOSPIR trial.

NPJ Prim Care Respir Med 2015 Nov 5;25:15067. Epub 2015 Nov 5.

Department of Medicine, Pulmonary Critical Care Center, University of Texas Health Science Center, San Antonio, TX, USA.

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http://dx.doi.org/10.1038/npjpcrm.2015.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634206PMC
November 2015

The Relationship among COPD Severity, Inhaled Corticosteroid Use, and the Risk of Pneumonia.

Ann Am Thorac Soc 2015 Oct;12(10):1587-9

5 Skane University Hospital Lund, Sweden.

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http://dx.doi.org/10.1513/AnnalsATS.201506-391LEDOI Listing
October 2015

A score to predict short-term risk of COPD exacerbations (SCOPEX).

Int J Chron Obstruct Pulmon Dis 2015 27;10:201-9. Epub 2015 Jan 27.

Department of Pulmonary/Critical Care, University of Texas Health Sciences Center and South Texas Veterans Healthcare System, San Antonio, TX, USA.

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http://dx.doi.org/10.2147/COPD.S69589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315304PMC
September 2015

Predicting loss of lung function in healthy people.

Lancet Respir Med 2015 Aug 6;3(8):590-1. Epub 2015 Jul 6.

School of Ageing and Chronic Disease, University Hospital Aintree, Liverpool L97AL, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(15)00236-2DOI Listing
August 2015

New Pharmacotherapeutic Approaches for Chronic Obstructive Pulmonary Disease.

Semin Respir Crit Care Med 2015 Aug 3;36(4):523-42. Epub 2015 Aug 3.

School of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1055/s-0035-1556057DOI Listing
August 2015

Reliever salbutamol use as a measure of exacerbation risk in chronic obstructive pulmonary disease.

BMC Pulm Med 2015 Aug 21;15:97. Epub 2015 Aug 21.

Clinical Sciences Department, Institute of Ageing and Chronic Disease, University Hospital Aintree, Lower Lane, Liverpool, L9 7AL, UK.

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http://dx.doi.org/10.1186/s12890-015-0077-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546184PMC
August 2015

Large trials, new knowledge: the changing face of COPD management.

Eur Respir J 2015 Jun 18;45(6):1692-703. Epub 2015 Mar 18.

Department of Clinical Sciences, University of Liverpool, University Hospital Aintree, Liverpool, UK

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http://dx.doi.org/10.1183/09031936.00179714DOI Listing
June 2015

Mild Chronic Obstructive Pulmonary Disease Does Exist-and Affects Gas Exchange during Exercise.

Authors:
Peter Calverley

Am J Respir Crit Care Med 2015 Jun;191(12):1346-7

1 School of Ageing and Chronic Diseases University of Liverpool Liverpool, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201504-0812EDDOI Listing
June 2015

One-year change in health status and subsequent outcomes in COPD.

Thorax 2015 May 17;70(5):420-5. Epub 2015 Mar 17.

Department of Research & Education, CIRO+, Centre of Expertise for Chronic Organ Failure, Horn, The Netherlands Faculty of Medicine and Life Sciences, REVAL-Rehabilitation Research Center, BIOMED-Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium.

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http://thorax.bmj.com/content/early/2015/03/17/thoraxjnl-201
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http://dx.doi.org/10.1136/thoraxjnl-2014-205697DOI Listing
May 2015

Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial.

Lancet 2015 Mar 13;385(9971):857-66. Epub 2015 Feb 13.

LungenClinic Grosshansdorf, Airway Research Center North, Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany; Department of Medicine, Christian-Albrechts University Kiel, Kiel, Germany.

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://linkinghub.elsevier.com/retrieve/pii/S014067361462410
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http://dx.doi.org/10.1016/S0140-6736(14)62410-7DOI Listing
March 2015

Inhaled glucocorticoids and COPD exacerbations.

N Engl J Med 2015 01;372(1):93-4

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http://dx.doi.org/10.1056/NEJMc1413308DOI Listing
January 2015