Publications by authors named "Peter C Adamson"

100Publications

Pediatric cancer research: Surviving COVID-19.

Pediatr Blood Cancer 2020 Jun 18:e28435. Epub 2020 Jun 18.

Division of Pediatric Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.28435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323039PMC
June 2020

Rituximab for High-Risk, Mature B-Cell Non-Hodgkin's Lymphoma in Children.

N Engl J Med 2020 06;382(23):2207-2219

From the Departments of Pediatric and Adolescent Oncology (V.M.-C., C.P.) and Clinical Research (G.V.), INSERM Unité 1015 (V.M.-C.), and the Unit of Biostatistics and Epidemiology and INSERM Unité 1018 (A.A.), Gustave Roussy, Université Paris-Saclay, Villejuif, France; the Department of Pediatric Hematology and Oncology, University of Padua, Padua, Italy (M.P.); the Department of Paediatric Haematology, Oncology, and Palliative Care, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge (G.A.A.B.), Cancer Research UK Clinical Trials Unit, Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham (K.W.), and the Department of Histopathology, Royal Marsden NHS Foundation Trust, London (A.W.) - all in the United Kingdom; the Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles (D.A.B.); the Department of Pediatric Hematology and Oncology, University of Valencia, Valencia, Spain (R.F.D.); the Division of Haematology-Oncology, Hospital for Sick Children, Toronto (S.A.); the Department of Pediatric Hematology and Oncology, University Hospitals Leuven, Leuven, Belgium (A.U.); the Center for Cancer and Immunology Research, Children's National Health System and George Washington University, Washington, DC (C.M.B.); Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands (J.Z.); the Department of Pediatric Hematology and Oncology, Semmelweis University, Budapest, Hungary (M.C.); the Department of Pediatric Bone Marrow Transplantation, Oncology, and Hematology, Wroclaw Medical University, Wroclaw, Poland (B.K.); the Department of Pediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong (A.K.C.); the Department of Pathology, University of Utah, Salt Lake City (R.R.M.); Children's Hospital of Philadelphia, Philadelphia (P.C.A.); and the National Cancer Institute, Center for Global Health, Rockville, MD (T.G.G.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1915315DOI Listing
June 2020

Survivorship Care Plans and the Commission on Cancer Standards: The Increasing Need for Better Strategies to Improve the Outcome for Survivors of Cancer.

JCO Oncol Pract 2020 Aug 8;16(8):447-450. Epub 2020 Apr 8.

University of Alabama at Birmingham, Birmingham, AL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JOP.19.00801DOI Listing
August 2020

Early Phase Pediatric Cancer Trials: Progress Highlights Challenges.

Authors:
Peter C Adamson

Oncologist 2020 Jun 16;25(6):468-469. Epub 2020 Jan 16.

Division of Oncology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2019-0942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288622PMC
June 2020

Emergent Radiation for Leukemic Optic Nerve Infiltration in a Child Receiving Intrathecal Methotrexate.

Pract Radiat Oncol 2019 Jul - Aug;9(4):226-230. Epub 2019 Apr 9.

Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prro.2019.04.004DOI Listing
April 2020

Unintended consequences of evolution of the Common Terminology Criteria for Adverse Events.

Pediatr Blood Cancer 2019 07 9;66(7):e27747. Epub 2019 Apr 9.

Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/pbc.27747
Publisher Site
http://dx.doi.org/10.1002/pbc.27747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681806PMC
July 2019

Fundamental problems with pediatric adaptive dosing of carboplatin using nuclear-medicine-based estimates of renal function.

Pediatr Blood Cancer 2019 06 15;66(6):e27672. Epub 2019 Feb 15.

Division of Oncology, The Children's Hospital of Philadelphia & Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.27672DOI Listing
June 2019

More on Anesthesia with a Large Mediastinal Mass.

Authors:
Peter C Adamson

N Engl J Med 2018 11;379(22):2182-3

Children’s Hospital of Philadelphia, Philadelphia, PA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1811989DOI Listing
November 2018

Dose Intensification Improves the Outcome of Ewing Sarcoma.

J Clin Oncol 2018 Sep 12:JCO2018793489. Epub 2018 Sep 12.

Richard Gorlick, The University of Texas MD Anderson Cancer Center, Houston, TX; Katherine A. Janeway, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA; and Peter C. Adamson, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Philadelphia, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2018.79.3489DOI Listing
September 2018

New Business Models to Accelerate Innovation in Pediatric Oncology Therapeutics: A Review.

JAMA Oncol 2018 09;4(9):1274-1280

MIT Laboratory for Financial Engineering, Sloan School of Management, Cambridge, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoncol.2018.1739DOI Listing
September 2018

Outcome of pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma with hypersensitivity to pegaspargase treated with PEGylated Erwinia asparaginase, pegcrisantaspase: A report from the Children's Oncology Group.

Pediatr Blood Cancer 2018 03 1;65(3). Epub 2017 Nov 1.

Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.26873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839116PMC
March 2018

Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases.

Bone 2018 04 20;109:276-280. Epub 2017 Jul 20.

Department of Medicine, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN 55905, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2017.07.019DOI Listing
April 2018

Dosing anticancer drugs in infants: Current approach and recommendations from the Children's Oncology Group's Chemotherapy Standardization Task Force.

Pediatr Blood Cancer 2017 Nov 16;64(11). Epub 2017 May 16.

Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.26636DOI Listing
November 2017

Challenges in drug development for children.

Authors:
Peter C Adamson

Clin Adv Hematol Oncol 2017 Jan;15(1):26-29

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
January 2017

Second monotherapy in childhood absence epilepsy.

Neurology 2017 Jan 16;88(2):182-190. Epub 2016 Dec 16.

From Children's National Health System (A.C.), Washington, DC; Montefiore Medical Center (S.S., D.M.), Albert Einstein College of Medicine, New York, NY; Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine (R.A., P.O.C., T.A.G.), OH; The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania (P.C.A., D.D.); and National Institute of Neurological Disorders and Stroke (D.G.H.), Bethesda, MD.

View Article

Download full-text PDF

Source
http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000003480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224720PMC
January 2017

Reaffirming and Clarifying the American Society of Clinical Oncology's Policy Statement on the Critical Role of Phase I Trials in Cancer Research and Treatment.

J Clin Oncol 2017 01 28;35(2):139-140. Epub 2016 Nov 28.

Jeffrey S. Weber, New York University Langone Medical Center, New York, NY; Laura A. Levit, American Society of Clinical Oncology, Alexandria, VA; Peter C. Adamson, The Children's Hospital of Philadelphia, Philadelphia, PA; Suanna S. Bruinooge, American Society of Clinical Oncology, Alexandria, VA; Howard A. Burris III, Sarah Cannon Research Institute, Nashville, TN; Michael A. Carducci, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Adam P. Dicker, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA; Mithat Gönen, Memorial Sloan Kettering Cancer Center, New York, NY; Stephen M. Keefe, University of Pennsylvania, Philadelphia, PA; Michael A. Postow, Memorial Sloan Kettering Cancer Center, New York, NY; Michael A. Thompson, Aurora Health Care, Milwaukee, WI; David M. Waterhouse, Oncology Hematology Care, Cincinnati, OH; Susan L. Weiner, Children's Cause for Cancer Advocacy, Washington, DC; and Lynn M. Schuchter, University of Pennsylvania, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.70.4692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559890PMC
January 2017

CYP2B6*6 or Not CYP2B6*6-That Remains a Question for Precision Medicine and Ketamine!

Anesthesiology 2016 12;125(6):1085-1087

From the Department of Anesthesiology and Critical Care Medicine (S.D.C.-S.), Department of Pediatrics (P.C.A.), and Department of Pediatrics and the Center for Applied Genomics (J.L., H.H.), The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ALN.0000000000001399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123751PMC
December 2016

The 2016 ASPHO Distinguished Career Award Goes to David G. Poplack, MD.

Pediatr Blood Cancer 2016 Jun;63 Suppl 1:S5-6

Division of Pediatric Hematology-Oncology, Duke University Medical Center, Durham, NC.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.25978DOI Listing
June 2016

Accuracy of Adverse Event Ascertainment in Clinical Trials for Pediatric Acute Myeloid Leukemia.

J Clin Oncol 2016 05 16;34(13):1537-43. Epub 2016 Feb 16.

Tamara P. Miller, Yimei Li, Marko Kavcic, Yuan-Shun V. Huang, Rochelle Bagatell, Alix E. Seif, Brian T. Fisher, Peter C. Adamson, and Richard Aplenc, The Children's Hospital of Philadelphia; Yimei Li, Andrea B. Troxel, Rochelle Bagatell, Alix E. Seif, Brian T. Fisher, Selina Luger, Peter C. Adamson, and Richard Aplenc, University of Pennsylvania School of Medicine, Philadelphia, PA; Lillian Sung, The Hospital for Sick Children, Toronto, Ontario, Canada; Todd A. Alonzo and Michael A. Pulsipher, University of Southern California; Michael A. Pulsipher, Children's Hospital of Los Angeles, Los Angeles; Todd A. Alonzo and Robert Gerbing, Children's Oncology Group, Monrovia, CA; Matt Hall, Children's Hospital Association, Overland Park, Kansas; Marla H. Daves, Children's Healthcare of Atlanta, Atlanta, GA; Terzah M. Horton, Texas Children's Hospital, Houston, TX; Jessica A. Pollard, Seattle Children's Hospital, Seattle, WA; and Alan S. Gamis, Children's Mercy Hospital, Kansas City, MO.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2015.65.5860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872308PMC
May 2016

When Life Expectancy is Not Short Enough: A Perspective on the National Institute for Health and Care Excellence (NICE) Preliminary Guidance for Dinutuximab.

Pediatr Blood Cancer 2016 Jun 6;63(6):962-3. Epub 2016 Jan 6.

Formerly, Division of Clinical Studies, The Institute of Cancer Research, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.25891DOI Listing
June 2016

Improving the outcome for children with cancer: Development of targeted new agents.

Authors:
Peter C Adamson

CA Cancer J Clin 2015 May-Jun;65(3):212-20. Epub 2015 Mar 9.

Chair, Children's Oncology Group, The Children's Hospital of Philadelphia, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3322/caac.21273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629487PMC
July 2015

The impact of chemotherapy shortages on COG and local clinical trials: a report from the Children's Oncology Group.

Pediatr Blood Cancer 2015 Jun 19;62(6):940-4. Epub 2015 Feb 19.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.25445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670038PMC
June 2015

American Society of Clinical Oncology policy statement update: the critical role of phase I trials in cancer research and treatment.

J Clin Oncol 2015 Jan 15;33(3):278-84. Epub 2014 Dec 15.

Jeffrey S. Weber, H. Lee Moffitt Cancer Center, Tampa, FL; Laura A. Levit and Suanna Bruinooge, American Society of Clinical Oncology, Alexandria, VA; Peter C. Adamson, Children's Hospital of Philadelphia; Adam P. Dicker, Jefferson Medical College, Thomas Jefferson University; Stephen M. Keefe and Lynn M. Schuchter, University of Pennsylvania, Philadelphia, PA; Howard A. Burris IIII, Sarah Cannon Research Institute, Nashville, TN; Michael A. Carducci, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD; Mithat Gönen and Michael A. Postow, Memorial Sloan-Kettering Cancer Center, New York, NY; Michael A. Thompson, Aurora Health Care, Milwaukee, WI; David M. Waterhouse, Oncology Hematology Care, Cincinnati, OH; and Susan L. Weiner, Children's Cause for Cancer Advocacy, Washington, DC.

View Article

Download full-text PDF

Source
http://jco.ascopubs.org/content/33/3/278.full.pdf
Web Search
http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.2635
Publisher Site
http://dx.doi.org/10.1200/JCO.2014.58.2635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516884PMC
January 2015

Reply to N.-K.V. Cheung et al.

J Clin Oncol 2014 Dec 17;32(36):4174-5. Epub 2014 Nov 17.

University of Washington School of Medicine, Seattle, WA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2014.58.7006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142206PMC
December 2014

Pharmacokinetic and pharmacodynamic properties of calaspargase pegol Escherichia coli L-asparaginase in the treatment of patients with acute lymphoblastic leukemia: results from Children's Oncology Group Study AALL07P4.

J Clin Oncol 2014 Dec 27;32(34):3874-82. Epub 2014 Oct 27.

Anne L. Angiolillo, Reuven J. Schore, Ashley R. Lane, and Gregory H. Reaman, Children's National Medical Center, Washington, DC; Meenakshi Devidas, Colleges of Medicine, Public Health and Health Professions, University of Florida; Charlotte Wood and Hao W. Zheng, Children's Oncology Group, Gainesville, FL; Michael J. Borowitz, Johns Hopkins Medical Institutions, Baltimore; Taha Keilani, Sigma-Tau Pharmaceuticals, Gaithersburg, MD; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Julie M. Gastier-Foster and Nyla A. Heerema, Ohio State University Wexner Medical Center; Julie M. Gastier-Foster, Ohio State University College of Medicine and Nationwide Children's Hospital, Columbus, OH; Mignon L. Loh, University of California at San Francisco, San Francisco, CA; Peter C. Adamson, Children's Hospital of Philadelphia, Philadelphia, PA; Brent Wood, University of Washington, Seattle, WA; Elizabeth A. Raetz and William L. Carroll, New York University Cancer Institute, New York University Langone Medical Center, New York, NY; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; and Stephen P. Hunger, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2014.55.5763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239306PMC
December 2014

A liquid chromatography/tandem mass spectrometry method for determination of obatoclax in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2014 Nov 16;971:30-4. Epub 2014 Sep 16.

Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, United States of America; Division of Oncology, The Children's Hospital of Philadelphia, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchromb.2014.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252240PMC
November 2014

Drug discovery in paediatric oncology: roadblocks to progress.

Nat Rev Clin Oncol 2014 12 16;11(12):732-9. Epub 2014 Sep 16.

Institute of Child Health, Cancer Section, University College London, 30 Guilford Street, London WC1N 1EH, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nrclinonc.2014.149
Publisher Site
http://dx.doi.org/10.1038/nrclinonc.2014.149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637819PMC
December 2014

The Children's Oncology Group Childhood Cancer Research Network (CCRN): case catchment in the United States.

Cancer 2014 Oct 29;120(19):3007-15. Epub 2014 May 29.

Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.28813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287245PMC
October 2014

Too few medicines for children with cancer--reply.

Authors:
Peter C Adamson

JAMA Pediatr 2014 Jun;168(6):583-4

Children's Oncology Group, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://archpedi.jamanetwork.com/article.aspx?doi=10.1001/jam
Publisher Site
http://dx.doi.org/10.1001/jamapediatrics.2014.18DOI Listing
June 2014

Declining childhood and adolescent cancer mortality.

Cancer 2014 Aug 22;120(16):2497-506. Epub 2014 May 22.

Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.28748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136455PMC
August 2014

It seemed like a good idea at the time.

Authors:
Peter C Adamson

Pediatr Blood Cancer 2014 Feb 30;61(2):187-8. Epub 2013 Sep 30.

Division of Clinical Pharmacology & Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.24669DOI Listing
February 2014

Preclinical evaluation of the PARP inhibitor, olaparib, in combination with cytotoxic chemotherapy in pediatric solid tumors.

Pediatr Blood Cancer 2014 Jan 4;61(1):145-50. Epub 2013 Sep 4.

Division of Pediatric Hematology/Oncology, Rainbow Babies & Children's Hospital, Cleveland, Ohio; Division of Clinical Pharmacology & Therapeutics, Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.24697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849815PMC
January 2014

Unintended consequences of regulatory initiatives in childhood cancer drug development.

Authors:
Peter C Adamson

JAMA Pediatr 2013 Oct;167(10):886-7

Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamapediatrics.2013.2488DOI Listing
October 2013

Evaluation of the retinoids with cisplatin and vincristine in xenograft models of neuroblastoma.

J Pediatr Hematol Oncol 2014 Jan;36(1):e23-7

*Divison of Pediatric Hematology/Oncology, Rainbow Babies and Children's Hospital, Cleveland, OH †Division of Clinical Pharmacology & Therapeutics, Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPH.0b013e3182915d4aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766379PMC
January 2014

Developing drugs for pediatric malignancies.

Authors:
Peter C Adamson

Clin Adv Hematol Oncol 2013 Apr;11(4):227-9

The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
April 2013

Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study.

Lancet Oncol 2013 May 16;14(6):472-80. Epub 2013 Apr 16.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, and Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(13)70095-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730818PMC
May 2013

Imaging in childhood cancer: a Society for Pediatric Radiology and Children's Oncology Group Joint Task Force report.

Pediatr Blood Cancer 2013 Aug 9;60(8):1253-60. Epub 2013 Apr 9.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.24533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636336PMC
August 2013

New drugs for children and adolescents with cancer: the need for novel development pathways.

Lancet Oncol 2013 Mar 20;14(3):e117-24. Epub 2013 Feb 20.

Division of Clinical Research, Institut Gustave Roussy, Paris-Sud University, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(13)70013-5DOI Listing
March 2013

The Children's Oncology Group's 2013 five year blueprint for research.

Authors:
Peter C Adamson

Pediatr Blood Cancer 2013 Jun 19;60(6):955-6. Epub 2012 Dec 19.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.24399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580969PMC
June 2013

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months.

Epilepsia 2013 Jan 21;54(1):141-55. Epub 2012 Nov 21.

Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/epi.12028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538883PMC
January 2013

Challenges and opportunities in childhood cancer drug development.

Nat Rev Cancer 2012 11 11;12(11):776-82. Epub 2012 Oct 11.

The Rainbow Babies and Children's Hospital, Pediatric Hematology/Oncology, Cleveland, Ohio 44106, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nrc3370
Publisher Site
http://dx.doi.org/10.1038/nrc3370DOI Listing
November 2012

Pediatric phase I trial and pharmacokinetic study of MLN8237, an investigational oral selective small-molecule inhibitor of Aurora kinase A: a Children's Oncology Group Phase I Consortium study.

Clin Cancer Res 2012 Nov 17;18(21):6058-64. Epub 2012 Sep 17.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-11-3251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008248PMC
November 2012

Sporadic adenocarcinoma of the colon in children: case series and review of the literature.

J Pediatr Hematol Oncol 2012 May;34(4):e137-41

Department of Radiology, Hepatology & Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPH.0b013e3182467f3eDOI Listing
May 2012

Quantification of serum fentanyl concentrations from umbilical cord blood during ex utero intrapartum therapy.

Anesth Analg 2012 Jun 24;114(6):1265-7. Epub 2011 Oct 24.

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0b013e3182378d21DOI Listing
June 2012

Preclinical evaluation of pemetrexed in pediatric solid tumors.

Pediatr Blood Cancer 2011 Dec 17;57(7):1233-5. Epub 2011 Aug 17.

Division of Clinical Pharmacology & Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.23286DOI Listing
December 2011

Preclinical evaluation of lestaurtinib (CEP-701) in combination with retinoids for neuroblastoma.

Cancer Chemother Pharmacol 2011 Dec 12;68(6):1469-75. Epub 2011 Apr 12.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-011-1623-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135359PMC
December 2011

Prescribing habits and caregiver satisfaction with resources for dosing children: rationale for more informative dosing guidance.

BMC Pediatr 2011 Apr 2;11:25. Epub 2011 Apr 2.

Department of Pediatrics, Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, 3501 Civic Center Blvd, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2431-11-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076266PMC
April 2011

Pediatric phase I trial and pharmacokinetic study of dasatinib: a report from the children's oncology group phase I consortium.

J Clin Oncol 2011 Mar 24;29(7):839-44. Epub 2011 Jan 24.

MSCE, The Children's Hospital of Philadelphia, Pediatric Oncology/Stem Cell Transplant, Philadelphia, PA 19104-4318, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2010.30.7231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068059PMC
March 2011

Approaches to clear residual chemotherapeutics from indwelling catheters in children with cancer.

Ther Drug Monit 2010 Dec;32(6):741-8

Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FTD.0b013e3181fa3c68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998595PMC
December 2010

A pediatric phase I trial and pharmacokinetic study of ispinesib: a Children's Oncology Group phase I consortium study.

Pediatr Blood Cancer 2010 Dec 13;55(7):1323-8. Epub 2010 Aug 13.

State University of New York, Health Science Center, Syracuse, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.22609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053384PMC
December 2010

A sensitive and selective liquid chromatography/tandem mass spectrometry method for determination of MLN8237 in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Sep 3;878(25):2369-73. Epub 2010 Jul 3.

Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15700232100042
Publisher Site
http://dx.doi.org/10.1016/j.jchromb.2010.06.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940716PMC
September 2010

Population pharmacokinetics of dexmedetomidine in infants after open heart surgery.

Anesth Analg 2010 May;110(5):1383-92

Division of Clinical Pharmacology and Therapeutics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0b013e3181d783c8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041635PMC
May 2010

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.

N Engl J Med 2010 Mar;362(9):790-9

Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital, 3333 Burnet Ave., MLC 2015, Cincinnati, OH 45229, USA.

View Article

Download full-text PDF

Source
http://www.nejm.org/doi/abs/10.1056/NEJMoa0902014
Publisher Site
http://dx.doi.org/10.1056/NEJMoa0902014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924476PMC
March 2010

Pharmacokinetics of orally administered ABT-751 in children with neuroblastoma and other solid tumors.

Cancer Chemother Pharmacol 2010 Sep 1;66(4):737-43. Epub 2010 Jan 1.

Pediatric Oncology Branch, National Cancer Institute, 10 Center Drive, Bethesda, MD 20892-1101, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-009-1218-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936731PMC
September 2010

It's not easy being small.

Authors:
Peter C Adamson

Pediatr Blood Cancer 2010 Mar;54(3):341-3

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, PA19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.22343DOI Listing
March 2010

Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias.

Cancer Chemother Pharmacol 2010 May 27;65(6):1125-30. Epub 2009 Sep 27.

Division of Clinical Pharmacology and Therapeutics, Children's Hospital of Philadelphia, Abramson Research Center, 3615 Civic Center Blvd., Suite 916, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-009-1120-8DOI Listing
May 2010

A phase II study of Campath-1H in children with relapsed or refractory acute lymphoblastic leukemia: a Children's Oncology Group report.

Pediatr Blood Cancer 2009 Dec;53(6):978-83

Division of Oncology, Children's National Medical Center, Washington, District of Columbia 20010, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.22209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120889PMC
December 2009

Current challenges in pediatric drug development.

Authors:
Peter C Adamson

Clin Adv Hematol Oncol 2008 Dec;6(12):883-4

Division of Clinical Pharmacology and Therapeutics, Clinical and Translational Research, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
December 2008