Peter Bugert

Peter Bugert

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Peter Bugert

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A novel allele of the atypical chemokine receptor 1 (ACKR1) gene containing the nucleotide change c.126 T>G (p.42Glu) encodes a third Duffy blood group protein sequence antithetical to that encoding Fy and Fy antigens.

Transfusion 2019 Jun 8;59(6):2158-2159. Epub 2019 Mar 8.

German Red Cross Blood Service Baden-Württemberg - Hessen, Institute Ulm, Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, and Institute of Transfusion Medicine, Ulm University, Ulm, Germany.

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http://dx.doi.org/10.1111/trf.15232DOI Listing
June 2019

Intratumoral platelet aggregate formation in a murine preclinical glioma model depends on podoplanin expression on tumor cells.

Blood Adv 2019 Apr;3(7):1092-1102

Division of Signal Transduction and Growth Control, German Cancer Research Center (DKFZ)-Center for Molecular Biology of the University of Heidelberg (ZMBH) Alliance, DKFZ, Heidelberg, Germany.

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http://dx.doi.org/10.1182/bloodadvances.2018015966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457221PMC
April 2019

SMC3 protein levels impact on karyotype and outcome in acute myeloid leukemia.

Leukemia 2019 Mar 15;33(3):795-799. Epub 2018 Oct 15.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.

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http://www.nature.com/articles/s41375-018-0287-6
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http://dx.doi.org/10.1038/s41375-018-0287-6DOI Listing
March 2019

Genome-wide association study identifies inversion in the locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

Gut 2018 10 28;67(10):1855-1863. Epub 2017 Jul 28.

Department of Molecular and Cell Biology, Center for Exocrine Disorders, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts, USA.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2017-314454
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http://dx.doi.org/10.1136/gutjnl-2017-314454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145291PMC
October 2018

Platelet deficiency in Tpo mice can both promote and suppress the metastasis of experimental breast tumors in an organ-specific manner.

Clin Exp Metastasis 2018 10 24;35(7):679-689. Epub 2018 Jul 24.

Medizinische Fakultät Mannheim, Universität Heidelberg, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1007/s10585-018-9924-8DOI Listing
October 2018

Granulocytes: From Basic Research to Clinical Use.

Transfus Med Hemother 2018 Oct 5;45(5):288-289. Epub 2018 Oct 5.

Institute Springe, German Red Cross Blood Donor Services NSTOB, Springe, Germany; Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany.

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https://www.karger.com/Article/FullText/494035
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http://dx.doi.org/10.1159/000494035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257150PMC
October 2018

Towards a Regional Registry of Extended Typed Blood Donors: Molecular Typing for Blood Group, Platelet and Granulocyte Antigens.

Transfus Med Hemother 2018 Oct 24;45(5):331-340. Epub 2018 Sep 24.

Institute of Transfusion Medicine and Immunology, Heidelberg University, Medical Faculty Mannheim, German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1159/000493555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257148PMC
October 2018

Granulocyte antibodies in male blood donors: can they trigger transfusion-related acute lung injury?

Transfusion 2018 08 29;58(8):1894-1901. Epub 2018 Apr 29.

Institute of Transfusion Medicine and Immunohematology, German Red Cross Blood Service Baden-Württemberg-Hessen, Goethe University Hospital, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1111/trf.14630DOI Listing
August 2018

The Impact of Using Genotyped Reagent Red Blood Cells in Antibody Identification.

Transfus Med Hemother 2018 Jul 24;45(4):218-224. Epub 2018 Jul 24.

Institute of Transfusion Medicine and Immunology, Heidelberg University, Medical Faculty Mannheim, German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany.

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https://www.karger.com/Article/FullText/491884
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http://dx.doi.org/10.1159/000491884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158584PMC
July 2018

Role of CD40 and ADAMTS13 in von Willebrand factor-mediated endothelial cell-platelet-monocyte interaction.

Proc Natl Acad Sci U S A 2018 06 23;115(24):E5556-E5565. Epub 2018 May 23.

Department of Cardiovascular Physiology, Heidelberg University, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.1801366115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004483PMC
June 2018

Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets.

Biochem Pharmacol 2017 12 28;145:54-63. Epub 2017 Sep 28.

Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.08.026DOI Listing
December 2017

A new genetic background for the Jr(a-) blood group phenotype caused by the ABCG2*439T allele encoding a p.Arg147Trp change.

Transfusion 2017 12 6;57(12):3063-3064. Epub 2017 Nov 6.

Institute of Transfusion Medicine and Immunology, Heidelberg University, Medical Faculty Mannheim, German Red Cross Blood Service Baden-Württemberg-Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1111/trf.14375DOI Listing
December 2017

Biological reproducibility of circulating P-Selectin, Thrombopoietin, GPIIb/IIIa and Thrombomodulin over one year.

Clin Biochem 2017 Nov 29;50(16-17):942-946. Epub 2017 May 29.

Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2017.05.017DOI Listing
November 2017

methylation in peripheral blood as a potential marker for the detection of pancreatic cancer: a case control study.

Oncotarget 2017 Sep 27;8(40):67614-67625. Epub 2017 Jun 27.

Molecular Biology of Breast Cancer, Department of Gynecology and Obstetrics, University of Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.18632/oncotarget.18757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620197PMC
September 2017

Creatine kinase in human erythrocytes: A genetic anomaly reveals presence of soluble brain-type isoform.

Blood Cells Mol Dis 2017 05 18;64:33-37. Epub 2017 Mar 18.

Univ. Grenoble Alpes, Laboratory of Fundamental and Applied Bioenergetics (LBFA), Grenoble, France; Inserm, U1055 Grenoble, France. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2017.03.008DOI Listing
May 2017

Expression of Inflammation-related Intercellular Adhesion Molecules in Cardiomyocytes In Vitro and Modulation by Pro-inflammatory Agents.

In Vivo 2016 May-Jun;30(3):213-7

First Department of Medicine, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany German Center for Cardiovascular Research, Partner Site, Heidelberg-Mannheim, Mannheim, Germany.

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March 2017

Embryonal Origin of MTSCC of Kidney May Explain its Morphological Heterogeneity: Diagnostic Impact of Genetic Analysis.

Anticancer Res 2017 03;37(3):1185-1189

Department of Urology, Medical School, University of Pecs, Pecs, Hungary

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http://dx.doi.org/10.21873/anticanres.11432DOI Listing
March 2017

The RHCE*Ce(501A) allele encodes the PARG antigen (RH60).

Transfusion 2017 02 31;57(2):484-486. Epub 2017 Jan 31.

Institute of Transfusion Medicine and Immunology, Heidelberg University, Medical Faculty Mannheim, German Red Cross Blood Service Baden-Württemberg-Hessen, Mannheim, Germany.

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http://doi.wiley.com/10.1111/trf.13985
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http://dx.doi.org/10.1111/trf.13985DOI Listing
February 2017

Fatal hemolytic disease of the newborn caused by an antibody to KEAL, a new low-prevalence Kell blood group antigen.

Transfusion 2017 01 28;57(1):217-218. Epub 2016 Sep 28.

Institute of Transfusion Medicine and Immunology, Heidelberg University, Medical Faculty Mannheim, German Red Cross Blood Service Baden-Württemberg-Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1111/trf.13852DOI Listing
January 2017

Megakaryocytes and platelets express nicotinic acetylcholine receptors but nicotine does not affect megakaryopoiesis or platelet function.

Platelets 2016 22;27(1):43-50. Epub 2015 Apr 22.

a Institute of Transfusion Medicine and Immunology, Mannheim Medical Faculty, Heidelberg University, German Red Cross Blood Service of Baden-Württemberg - Hessen , Mannheim , Germany.

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http://dx.doi.org/10.3109/09537104.2015.1026803DOI Listing
October 2016

The H blood group system.

Immunohematology 2016 Sep;32(3):112-118

Associate Professor, Institute of Transfusion Medicine and Immunology, Heidelberg University, Medical Faculty Mannheim, and German Red Cross Blood Service Baden-Württemberg-Hessen, Mannheim, Germany.

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September 2016

Innate Immune System for Diagnostics and Therapy: Progress in Fundamental Knowledge and Clinical Application.

Transfus Med Hemother 2016 Mar 31;43(2):63-4. Epub 2016 Mar 31.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University; German Red Cross Blood Service Baden-Württemberg - Hessen; Mannheim, Germany.

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http://dx.doi.org/10.1159/000445488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872049PMC
March 2016

PCR with sequence-specific primers for typing of diallelic blood groups.

Methods Mol Biol 2015 ;1310:71-81

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, German Red Cross Blood Service Baden-Württemberg - Hessen gGmbH, Heidelberg University, Friedrich-Ebert-Straße 107, 68167, Mannheim, Germany,

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http://dx.doi.org/10.1007/978-1-4939-2690-9_6DOI Listing
February 2016

454-Sequencing™ for the KEL, JR, and LAN Blood Groups.

Methods Mol Biol 2015 ;1310:123-33

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service Baden-Württemberg - Hessen, Friedrich-Ebert-Straße 107, Mannheim, 68167, Germany,

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http://link.springer.com/10.1007/978-1-4939-2690-9_11
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http://dx.doi.org/10.1007/978-1-4939-2690-9_11DOI Listing
February 2016

Distribution of the CCR5-delta32 deletion in Southwest Germany.

Anthropol Anz 2015 3;72(3):303-9. Epub 2015 Feb 3.

Cellex GmbH, Dresden, Germany.

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http://dx.doi.org/10.1127/anthranz/2015/0479DOI Listing
November 2015

Molecular Screening for Vel- Blood Donors in Southwestern Germany.

Transfus Med Hemother 2015 Nov 3;42(6):356-60. Epub 2015 Nov 3.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1159/000440791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698648PMC
November 2015

DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood.

Int J Cancer 2015 Apr 24;136(8):1845-55. Epub 2014 Sep 24.

Molecular Biology of Breast Cancer, Department of Gynecology and Obstetrics, University of Heidelberg, Heidelberg, Germany; Molecular Epidemiology (C080), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29205DOI Listing
April 2015

Effect of simvastatin on MMPs and TIMPs in human brain endothelial cells and experimental stroke.

Transl Stroke Res 2015 Apr 5;6(2):156-9. Epub 2014 Dec 5.

Department of Neurology, Universitätsmedizin Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany,

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http://link.springer.com/content/pdf/10.1007/s12975-014-0381
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http://link.springer.com/10.1007/s12975-014-0381-7
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http://dx.doi.org/10.1007/s12975-014-0381-7DOI Listing
April 2015

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

Authors:
Maria Kabisch Justo Lorenzo Bermejo Thomas Dünnebier Shibo Ying Kyriaki Michailidou Manjeet K Bolla Qin Wang Joe Dennis Mitul Shah Barbara J Perkins Kamila Czene Hatef Darabi Mikael Eriksson Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Patrick Neven Stephanie Peeters Caroline Weltens Fergus J Couch Janet E Olson Xianshu Wang Kristen Purrington Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel dos-Santos-Silva Nichola Johnson Olivia Fletcher Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Marjanka K Schmidt Annegien Broeks Sten Cornelissen Frans B L Hogervorst Jingmei Li Judith S Brand Keith Humphreys Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marmé Rongxi Yang Peter Bugert Anna González-Neira Javier Benitez M Pilar Zamora Jose I Arias Perez Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle Mieke Kriege Linetta B Koppert John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Seth Slettedahl Amanda E Toland Celine Vachon Drakoulis Yannoukakos Graham G Giles Roger L Milne Catriona McLean Peter A Fasching Matthias Ruebner Arif B Ekici Matthias W Beckmann Hermann Brenner Aida K Dieffenbach Volker Arndt Christa Stegmaier Alan Ashworth Nicholas Orr Minouk J Schoemaker Anthony Swerdlow Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Paolo Radice Paolo Peterlongo Giulietta Scuvera Stefano Fortuzzi Natalia Bogdanova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Wei Zheng Martha J Shrubsole Qiuyin Cai Diana Torres Hoda Anton-Culver Vessela Kristensen François Bacot Daniel C Tessier Daniel Vincent Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Jacques Simard Georgia Chenevix-Trench Per Hall Paul D P Pharoah Alison M Dunning Douglas F Easton Ute Hamann

Carcinogenesis 2015 Feb 13;36(2):256-71. Epub 2015 Jan 13.

Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany,

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http://dx.doi.org/10.1093/carcin/bgu326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335262PMC
February 2015

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.

Authors:
Kristen S Purrington Seth Slettedahl Manjeet K Bolla Kyriaki Michailidou Kamila Czene Heli Nevanlinna Stig E Bojesen Irene L Andrulis Angela Cox Per Hall Jane Carpenter Drakoulis Yannoukakos Christopher A Haiman Peter A Fasching Arto Mannermaa Robert Winqvist Hermann Brenner Annika Lindblom Georgia Chenevix-Trench Javier Benitez Anthony Swerdlow Vessela Kristensen Pascal Guénel Alfons Meindl Hatef Darabi Mikael Eriksson Rainer Fagerholm Kristiina Aittomäki Carl Blomqvist Børge G Nordestgaard Sune F Nielsen Henrik Flyger Xianshu Wang Curtis Olswold Janet E Olson Anna Marie Mulligan Julia A Knight Sandrine Tchatchou Malcolm W R Reed Simon S Cross Jianjun Liu Jingmei Li Keith Humphreys Christine Clarke Rodney Scott Florentia Fostira George Fountzilas Irene Konstantopoulou Brian E Henderson Fredrick Schumacher Loic Le Marchand Arif B Ekici Arndt Hartmann Matthias W Beckmann Jaana M Hartikainen Veli-Matti Kosma Vesa Kataja Arja Jukkola-Vuorinen Katri Pylkäs Saila Kauppila Aida Karina Dieffenbach Christa Stegmaier Volker Arndt Sara Margolin Rosemary Balleine Jose Ignacio Arias Perez M Pilar Zamora Primitiva Menéndez Alan Ashworth Michael Jones Nick Orr Patrick Arveux Pierre Kerbrat Thérèse Truong Peter Bugert Amanda E Toland Christine B Ambrosone France Labrèche Mark S Goldberg Martine Dumont Argyrios Ziogas Eunjung Lee Gillian S Dite Carmel Apicella Melissa C Southey Jirong Long Martha Shrubsole Sandra Deming-Halverson Filomena Ficarazzi Monica Barile Paolo Peterlongo Katarzyna Durda Katarzyna Jaworska-Bieniek Robert A E M Tollenaar Caroline Seynaeve Thomas Brüning Yon-Dschun Ko Carolien H M Van Deurzen John W M Martens Mieke Kriege Jonine D Figueroa Stephen J Chanock Jolanta Lissowska Ian Tomlinson Michael J Kerin Nicola Miller Andreas Schneeweiss William J Tapper Susan M Gerty Lorraine Durcan Catriona Mclean Roger L Milne Laura Baglietto Isabel dos Santos Silva Olivia Fletcher Nichola Johnson Laura J Van'T Veer Sten Cornelissen Asta Försti Diana Torres Thomas Rüdiger Anja Rudolph Dieter Flesch-Janys Stefan Nickels Caroline Weltens Giuseppe Floris Matthieu Moisse Joe Dennis Qin Wang Alison M Dunning Mitul Shah Judith Brown Jacques Simard Hoda Anton-Culver Susan L Neuhausen John L Hopper Natalia Bogdanova Thilo Dörk Wei Zheng Paolo Radice Anna Jakubowska Jan Lubinski Peter Devillee Hiltrud Brauch Maartje Hooning Montserrat García-Closas Elinor Sawyer Barbara Burwinkel Frederick Marmee Diana M Eccles Graham G Giles Julian Peto Marjanka Schmidt Annegien Broeks Ute Hamann Jenny Chang-Claude Diether Lambrechts Paul D P Pharoah Douglas Easton V Shane Pankratz Susan Slager Celine M Vachon Fergus J Couch

Hum Mol Genet 2014 Nov 13;23(22):6034-46. Epub 2014 Jun 13.

Department of Health Sciences Research, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA,

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http://dx.doi.org/10.1093/hmg/ddu300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204763PMC
November 2014

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium.

Authors:
Roger L Milne Barbara Burwinkel Kyriaki Michailidou Jose-Ignacio Arias-Perez M Pilar Zamora Primitiva Menéndez-Rodríguez David Hardisson Marta Mendiola Anna González-Neira Guillermo Pita M Rosario Alonso Joe Dennis Qin Wang Manjeet K Bolla Anthony Swerdlow Alan Ashworth Nick Orr Minouk Schoemaker Yon-Dschun Ko Hiltrud Brauch Ute Hamann Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Keitaro Matsuo Hidemi Ito Hiroji Iwata Kazuo Tajima Jingmei Li Judith S Brand Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Diether Lambrechts Gilian Peuteman Marie-Rose Christiaens Ann Smeets Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katazyna Durda Mikael Hartman Miao Hui Wei Yen Lim Ching Wan Chan Federick Marme Rongxi Yang Peter Bugert Annika Lindblom Sara Margolin Montserrat García-Closas Stephen J Chanock Jolanta Lissowska Jonine D Figueroa Stig E Bojesen Børge G Nordestgaard Henrik Flyger Maartje J Hooning Mieke Kriege Ans M W van den Ouweland Linetta B Koppert Olivia Fletcher Nichola Johnson Isabel dos-Santos-Silva Julian Peto Wei Zheng Sandra Deming-Halverson Martha J Shrubsole Jirong Long Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Angela Cox Simon S Cross Malcolm W R Reed Marjanka K Schmidt Annegien Broeks Sten Cornelissen Linde Braaf Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Jacques Simard Martine Dumont Mark S Goldberg France Labrèche Peter A Fasching Alexander Hein Arif B Ekici Matthias W Beckmann Paolo Radice Paolo Peterlongo Jacopo Azzollini Monica Barile Elinor Sawyer Ian Tomlinson Michael Kerin Nicola Miller John L Hopper Daniel F Schmidt Enes Makalic Melissa C Southey Soo Hwang Teo Cheng Har Yip Kavitta Sivanandan Wan-Ting Tay Chen-Yang Shen Chia-Ni Hsiung Jyh-Cherng Yu Ming-Feng Hou Pascal Guénel Therese Truong Marie Sanchez Claire Mulot William Blot Qiuyin Cai Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Natalia Bogdanova Thilo Dörk Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Xiao-Ou Shu Wei Lu Yu-Tang Gao Ben Zhang Fergus J Couch Amanda E Toland Drakoulis Yannoukakos Suleeporn Sangrajrang James McKay Xianshu Wang Janet E Olson Celine Vachon Kristen Purrington Gianluca Severi Laura Baglietto Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Kamila Czene Mikael Eriksson Keith Humphreys Hatef Darabi Shahana Ahmed Mitul Shah Paul D P Pharoah Per Hall Graham G Giles Javier Benítez Alison M Dunning Georgia Chenevix-Trench Douglas F Easton

Hum Mol Genet 2014 Nov 18;23(22):6096-111. Epub 2014 Jun 18.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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http://hmg.oxfordjournals.org/content/early/2014/07/04/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu311
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http://dx.doi.org/10.1093/hmg/ddu311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204770PMC
November 2014

SCN5A mutations and polymorphisms in patients with ventricular fibrillation during acute myocardial infarction.

Mol Med Rep 2014 Oct 21;10(4):2039-44. Epub 2014 Jul 21.

Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany.

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http://dx.doi.org/10.3892/mmr.2014.2401DOI Listing
October 2014

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.

Authors:
Brian M Wolpin Cosmeri Rizzato Peter Kraft Charles Kooperberg Gloria M Petersen Zhaoming Wang Alan A Arslan Laura Beane-Freeman Paige M Bracci Julie Buring Federico Canzian Eric J Duell Steven Gallinger Graham G Giles Gary E Goodman Phyllis J Goodman Eric J Jacobs Aruna Kamineni Alison P Klein Laurence N Kolonel Matthew H Kulke Donghui Li Núria Malats Sara H Olson Harvey A Risch Howard D Sesso Kala Visvanathan Emily White Wei Zheng Christian C Abnet Demetrius Albanes Gabriella Andreotti Melissa A Austin Richard Barfield Daniela Basso Sonja I Berndt Marie-Christine Boutron-Ruault Michelle Brotzman Markus W Büchler H Bas Bueno-de-Mesquita Peter Bugert Laurie Burdette Daniele Campa Neil E Caporaso Gabriele Capurso Charles Chung Michelle Cotterchio Eithne Costello Joanne Elena Niccola Funel J Michael Gaziano Nathalia A Giese Edward L Giovannucci Michael Goggins Megan J Gorman Myron Gross Christopher A Haiman Manal Hassan Kathy J Helzlsouer Brian E Henderson Elizabeth A Holly Nan Hu David J Hunter Federico Innocenti Mazda Jenab Rudolf Kaaks Timothy J Key Kay-Tee Khaw Eric A Klein Manolis Kogevinas Vittorio Krogh Juozas Kupcinskas Robert C Kurtz Andrea LaCroix Maria T Landi Stefano Landi Loic Le Marchand Andrea Mambrini Satu Mannisto Roger L Milne Yusuke Nakamura Ann L Oberg Kouros Owzar Alpa V Patel Petra H M Peeters Ulrike Peters Raffaele Pezzilli Ada Piepoli Miquel Porta Francisco X Real Elio Riboli Nathaniel Rothman Aldo Scarpa Xiao-Ou Shu Debra T Silverman Pavel Soucek Malin Sund Renata Talar-Wojnarowska Philip R Taylor George E Theodoropoulos Mark Thornquist Anne Tjønneland Geoffrey S Tobias Dimitrios Trichopoulos Pavel Vodicka Jean Wactawski-Wende Nicolas Wentzensen Chen Wu Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Robert Hoover Patricia Hartge Charles Fuchs Stephen J Chanock Rachael S Stolzenberg-Solomon Laufey T Amundadottir

Nat Genet 2014 Sep 3;46(9):994-1000. Epub 2014 Aug 3.

1] Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. [2].

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http://dx.doi.org/10.1038/ng.3052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191666PMC
September 2014

Mutational analysis of ATP8B1 in patients with chronic pancreatitis.

PLoS One 2013 19;8(11):e80553. Epub 2013 Nov 19.

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands ; Department of Metabolic Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834041PMC
August 2014

Late-onset myasthenia gravis - CTLA4(low) genotype association and low-for-age thymic output of naïve T cells.

J Autoimmun 2014 Aug 24;52:122-9. Epub 2013 Dec 24.

Institute of Pathology, University of Würzburg, Würzburg, Germany; Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68135 Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2013.12.006DOI Listing
August 2014

Donor research - an upcoming field of interest all over the world!

Transfus Med Hemother 2014 Jul 21;41(4):240-1. Epub 2014 Jul 21.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University; German Red Cross Blood Service Baden-Wuerttemberg - Hesse; Mannheim, Germany.

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http://dx.doi.org/10.1159/000365943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164057PMC
July 2014

Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation.

Inflamm Bowel Dis 2014 Apr;20(4):671-84

1Technische Universität München, ZIEL-Research Center for Nutrition and Food Science, Biochemistry Unit, Weihenstephan, Germany; 2Institute of Pathology, Charité-Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany; 3Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France; 4Université Lille Nord de France, Lille, France; 5Centre national de la recherche scientifique, Unité Mixte de Recherche, Lille, France; 6Institut National de la Santé et de la Recherche Médicale, Lille, France; 7Technische Universität München, ZIEL-Research Center for Nutrition and Food Science, Biofunctionality Unit, Weihenstephan, Germany; 8Institute of Microbiology and Hygiene, Charité-Universitätsmedizin Berlin, Campus Benjamin-Franklin, Berlin, Germany; 9Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, North Carolina; 10Department of Gastroenterology, Infectiology and Rheumatology, Charité-Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany; 11Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service of Baden-Württemberg-Hessen, Mannheim, Germany; 12Else Kröner-Fresenius-Zentrum für Ernährungsmedizin (EKFZ) and ZIEL-Research Center for Nutrition and Food Science, Technische Universität München (TUM), Weihenstephan, Germany; and 13Department of Pediatrics, Klinikum rechts der Isar (MRI), Technische Universität München (TUM), Munich, Germany. T. Wuensch is now with Department of Cell and Molecular Biology, Karolinska Institute, von Eulersväg 3, Stockholm, Sweden.

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http://dx.doi.org/10.1097/01.MIB.0000443336.71488.08DOI Listing
April 2014

Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia.

Cerebrovasc Dis 2013 25;35(6):514-20. Epub 2013 Jun 25.

Department of Neurology, UniversitätsMedizin Mannheim, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1159/000350731DOI Listing
March 2014

Acetylsalicylic acid enhances tachyphylaxis of repetitive capsaicin responses in TRPV1-GFP expressing HEK293 cells.

Neurosci Lett 2014 Mar 2;563:101-6. Epub 2014 Feb 2.

Department of Neurophysiology, Centre for Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim of the University of Heidelberg, Ludolf-Krehl-Str.13-17, D-68167 Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2014.01.050DOI Listing
March 2014

N-octanoyl-dopamine is a potent inhibitor of platelet function.

Platelets 2013 23;24(6):428-34. Epub 2012 Aug 23.

Department of Nephrology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://www.tandfonline.com/doi/full/10.3109/09537104.2012.71
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http://dx.doi.org/10.3109/09537104.2012.715217DOI Listing
February 2014

A single-tube real-time PCR assay for Mycoplasma detection as a routine quality control of cell therapeutics.

Transfus Med Hemother 2014 Feb 19;41(1):83-9. Epub 2013 Dec 19.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University; German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1159/000357096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949616PMC
February 2014

Evaluation of the effects of different culture media on the myogenic differentiation potential of adipose tissue- or bone marrow-derived human mesenchymal stem cells.

Int J Mol Med 2014 Jan 13;33(1):160-70. Epub 2013 Nov 13.

Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.

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http://dx.doi.org/10.3892/ijmm.2013.1555DOI Listing
January 2014

A Novel ABO Gene Variant Leads to Discrepant Results in Forward/Reverse and Molecular Blood Grouping.

Transfus Med Hemother 2013 Dec 27;40(6):454-8. Epub 2013 Oct 27.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University; German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Magdeburg, Germany.

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http://dx.doi.org/10.1159/000356378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901630PMC
December 2013

Variants in CPA1 are strongly associated with early onset chronic pancreatitis.

Nat Genet 2013 Oct 18;45(10):1216-20. Epub 2013 Aug 18.

1] Else Kröner-Fresenius-Zentrum für Ernährungsmedizin (EKFZ), Technische Universität München (TUM), Freising, Germany. [2] Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL), TUM, Freising, Germany. [3] Department of Pediatrics, Klinikum Rechts der Isar (MRI), TUM, Munich, Germany.

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http://dx.doi.org/10.1038/ng.2730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909499PMC
October 2013

Development of Anti-G, Anti-C and Anti-Jk(b) in a 22-Year-Old Mother during Her Fourth Pregnancy.

Transfus Med Hemother 2013 Jun 17;40(3):207-9. Epub 2013 May 17.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1159/000351518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725028PMC
June 2013

The gears keep turning: current progress in platelet function testing.

Authors:
Peter Bugert

Transfus Med Hemother 2013 Apr;40(2):71

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University; German Red Cross Blood Service Baden-Württemberg - Hessen; Mannheim, Germany.

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http://dx.doi.org/10.1159/000350692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638922PMC
April 2013

A comparative analysis of the adipogenic potential in human mesenchymal stromal cells from cord blood and other sources.

Cytotherapy 2013 Jan;15(1):76-88

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service Baden-Württemberg-Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.jcyt.2012.11.001DOI Listing
January 2013

The G534E-polymorphism of the gene encoding the factor VII-activating protease is a risk factor for venous thrombosis and recurrent events.

Thromb Res 2012 Sep 14;130(3):441-4. Epub 2012 Mar 14.

Institute for Clinical Chemistry, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.thromres.2012.02.009DOI Listing
September 2012

100 Years after von Dungern & Hirschfeld: Kinship Investigation from Blood Groups to SNPs.

Transfus Med Hemother 2012 Jun 15;39(3):161-162. Epub 2012 May 15.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, Germany.

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http://dx.doi.org/000339263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375122PMC
June 2012

Blood Group ABO Genotyping in Paternity Testing.

Transfus Med Hemother 2012 Jun 15;39(3):182-186. Epub 2012 May 15.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University; German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany.

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http://dx.doi.org/000339235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375137PMC
June 2012

Cholinergic drugs inhibit in vitro megakaryopoiesis via the alpha7-nicotinic acetylcholine receptor.

Platelets 2011 9;22(5):390-5. Epub 2011 Mar 9.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service Baden-Württemberg - Hessen, Mannheim, Germany.

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http://dx.doi.org/10.3109/09537104.2010.551304DOI Listing
December 2011

The presence of functionally relevant toll-like receptor polymorphisms does not significantly correlate with development or outcome of sepsis.

Genet Test Mol Biomarkers 2011 Sep 1;15(9):645-51. Epub 2011 Jul 1.

Institute for Clinical Chemistry, University Hospital Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1089/gtmb.2010.0258DOI Listing
September 2011

The interleukin-6 promoter (-597/-572/-174)genotype does not affect interleukin-6 production in hemodialysis patients.

J Interferon Cytokine Res 2011 Aug 2;31(8):639-42. Epub 2011 Mar 2.

Institute of Transfusion Medicine and Immunology, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1089/jir.2010.0141DOI Listing
August 2011

No evidence for an association between the rs2824292 variant at chromosome 21q21 and ventricular fibrillation during acute myocardial infarction in a German population.

Clin Chem Lab Med 2011 Jul 17;49(7):1237-9. Epub 2011 May 17.

Institute of Transfusion Medicine and Immunology, German Red Cross Blood Service of Baden-Württemberg-Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1515/CCLM.2011.190DOI Listing
July 2011

Human platelets express functional alpha7-nicotinic acetylcholine receptors.

Arterioscler Thromb Vasc Biol 2011 Apr 4;31(4):928-34. Epub 2010 Nov 4.

Institute of Transfusion Medicine and Immunology, German Red Cross Blood Service of Baden-Württemberg-Hessen, Friedrich-Ebert-Straße 107, D-68167 Mannheim, Germany.

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http://dx.doi.org/10.1161/ATVBAHA.110.218297DOI Listing
April 2011

Pathogen Reduction in Blood Products: What's Behind These Techniques?

Transfus Med Hemother 2011 ;38(1):5-6

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1159/000324457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132975PMC
January 2011

Altered gene expression in human adipose stem cells cultured with fetal bovine serum compared to human supplements.

Tissue Eng Part A 2010 Nov 31;16(11):3467-84. Epub 2010 Aug 31.

Medical Faculty Mannheim, Institute of Transfusion Medicine and Immunology, German Red Cross Blood Service of Baden-Württemberg-Hessen, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1089/ten.TEA.2009.0727DOI Listing
November 2010

The P-selectin gene polymorphism Val168Met: a novel risk marker for the occurrence of primary ventricular fibrillation during acute myocardial infarction.

J Cardiovasc Electrophysiol 2010 Nov;21(11):1260-5

1st Department of Medicine, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1111/j.1540-8167.2010.01833.xDOI Listing
November 2010

The Effect of Psychoactive Drugs on in vitro Platelet Function.

Transfus Med Hemother 2010 25;37(5):293-298. Epub 2010 Aug 25.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, University of Heidelberg, German Red Cross Blood Service of Baden-Württemberg - Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1159/000319841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980515PMC
August 2010

A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk.

Breast Cancer Res Treat 2010 Jun 18;121(3):693-702. Epub 2009 Nov 18.

Helmholtz-University Group Molecular Epidemiology, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 581, 69120 Heidelberg, Germany.

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http://link.springer.com/10.1007/s10549-009-0633-5
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http://dx.doi.org/10.1007/s10549-009-0633-5DOI Listing
June 2010

In vitro analysis of radiation-induced dermal wounds.

Otolaryngol Head Neck Surg 2010 Jun 24;142(6):845-50. Epub 2010 Apr 24.

Department of Otolaryngology-Head and Neck Surgery, Ruprecht Karls-University Heidelberg, Faculty of Medicine Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.otohns.2010.01.033DOI Listing
June 2010

Spectroscopic diagnosis of myocardial infarction and heart failure by Fourier transform infrared spectroscopy in serum samples.

Appl Spectrosc 2010 Mar;64(3):262-7

Department of Medicine II, Mannheim Medical Faculty of the University Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.

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http://dx.doi.org/10.1366/000370210790918508DOI Listing
March 2010

TIMP-2 gene polymorphism is associated with intracerebral hemorrhage.

Cerebrovasc Dis 2009 16;28(6):558-63. Epub 2009 Oct 16.

Department of Neurology, Universitatsklinikum Mannheim, Theodor-Kutzer-Ufer 1-3, Mannheim, Germany.

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http://dx.doi.org/10.1159/000247599DOI Listing
February 2010

Clinical and Laboratory Diagnosis of Inherited Platelet Function Disorders.

Authors:
Peter Bugert

Transfus Med Hemother 2010 ;37(5):229-230

Institute of Transfusion Medicine and Immunology, Heidelberg University, Medical Faculty Mannheim, German Red Cross Blood Service of Baden-Württemberg - Hessen gGmbH, Mannheim, Germany.

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http://dx.doi.org/10.1159/000321076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980506PMC
January 2010

Optimized PCR with sequence specific primers (PCR-SSP) for fast and efficient determination of Interleukin-6 Promoter -597/-572/-174Haplotypes.

BMC Res Notes 2009 Dec 10;2:245. Epub 2009 Dec 10.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, Friedrich-Ebert-Strasse 107, 68167 Mannheim, Germany, DRK-Blutspendedienst Baden-Württemberg - Hessen, Germany.

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http://dx.doi.org/10.1186/1756-0500-2-245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797812PMC
December 2009