Peter Arner

Peter Arner

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The Rho GTPase RND3 regulates adipocyte lipolysis.

Metabolism 2019 Dec 28;101:153999. Epub 2019 Oct 28.

Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, N-5020 Bergen, Norway; Hormone Laboratory, Haukeland University Hospital, N-5021 Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.153999DOI Listing
December 2019

INFLUENCE OF AGEING AND MENSTRUAL STATUS ON SUBCUTANEOUS FAT CELL LIPOLYSIS.

J Clin Endocrinol Metab 2019 Nov 30. Epub 2019 Nov 30.

All authors are from the Department of Medicine (H7), Karolinska Institutet at Karolinska University Hospital - Huddinge, Stockholm, Sweden.

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http://dx.doi.org/10.1210/clinem/dgz245DOI Listing
November 2019

Fat Tissue Growth and Development in Humans.

Authors:
Peter Arner

Nestle Nutr Inst Workshop Ser 2018 10;89:37-45. Epub 2018 Jul 10.

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http://dx.doi.org/10.1159/000486491DOI Listing
October 2019

Human-Specific Function of IL-10 in Adipose Tissue Linked to Insulin Resistance.

J Clin Endocrinol Metab 2019 Oct;104(10):4552-4562

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.

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https://academic.oup.com/jcem/advance-article/doi/10.1210/jc
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http://dx.doi.org/10.1210/jc.2019-00341DOI Listing
October 2019

MicroRNA-27a/b-3p and PPARG regulate SCAMP3 through a feed-forward loop during adipogenesis.

Sci Rep 2019 Sep 25;9(1):13891. Epub 2019 Sep 25.

RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230-0045, Japan.

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http://dx.doi.org/10.1038/s41598-019-50210-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761119PMC
September 2019

The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake.

EBioMedicine 2019 Aug 3;46:368-380. Epub 2019 Aug 3.

Laboratory of Molecular and Cellular Cardiology, Dep. of Clinical Biochemistry and Pharmacology, Odense University Hospital, Denmark; Danish Center for Regenerative Medicine (danishcrm.com), Odense University Hospital, Denmark; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark; Clinical Institute, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.07.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711890PMC
August 2019

Apolipoprotein M: a novel adipokine decreasing with obesity and upregulated by calorie restriction.

Am J Clin Nutr 2019 Jun;109(6):1499-1510

Franco-Czech Laboratory for Clinical Research on Obesity, Third Faculty of Medicine, Prague and Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Toulouse, France.

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http://dx.doi.org/10.1093/ajcn/nqy331DOI Listing
June 2019

MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition.

EBioMedicine 2019 Jun 28;44:467-475. Epub 2019 May 28.

Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LE, UK; NIHR Oxford Biomedical Research Centre, OUH Trust, Oxford OX3 7LE, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.05.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607082PMC
June 2019

Prospective analyses of white adipose tissue gene expression in relation to long-term body weight changes.

Int J Obes (Lond) 2019 Jun 4. Epub 2019 Jun 4.

Department of Medicine (H7), Huddinge, Karolinska Institutet, 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41366-019-0385-1DOI Listing
June 2019

The impact of dietary fatty acids on human adipose tissue.

Proc Nutr Soc 2019 May 24:1-5. Epub 2019 May 24.

Department of Medicine (H7),Karolinska Institutet,Stockholm 141 86,Sweden.

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http://dx.doi.org/10.1017/S0029665119000624DOI Listing
May 2019

Screening of potential adipokines identifies S100A4 as a marker of pernicious adipose tissue and insulin resistance.

Int J Obes (Lond) 2018 12 30;42(12):2047-2056. Epub 2018 Jan 30.

Department of Medicine (H7), Karolinska Institutet, 141 86, Stockholm, Sweden.

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http://www.nature.com/articles/s41366-018-0018-0
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http://dx.doi.org/10.1038/s41366-018-0018-0DOI Listing
December 2018

Mapping of biguanide transporters in human fat cells and their impact on lipolysis.

Diabetes Obes Metab 2018 10 5;20(10):2416-2425. Epub 2018 Jul 5.

Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://doi.wiley.com/10.1111/dom.13395
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http://dx.doi.org/10.1111/dom.13395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133731PMC
October 2018

MicroRNAs-361-5p and miR-574-5p associate with human adipose morphology and regulate EBF1 expression in white adipose tissue.

Mol Cell Endocrinol 2018 09 27;472:50-56. Epub 2017 Nov 27.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, SE-14186 Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03037207173060
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http://dx.doi.org/10.1016/j.mce.2017.11.018DOI Listing
September 2018

Body fat mass and distribution as predictors of metabolic outcome and weight loss after Roux-en-Y gastric bypass.

Surg Obes Relat Dis 2018 07 17;14(7):936-942. Epub 2018 Mar 17.

Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.soard.2018.03.012DOI Listing
July 2018

Weight Gain and Impaired Glucose Metabolism in Women Are Predicted by Inefficient Subcutaneous Fat Cell Lipolysis.

Cell Metab 2018 Jul 31;28(1):45-54.e3. Epub 2018 May 31.

Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm 141 86, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.05.004DOI Listing
July 2018

Long Non-Coding RNAs Associated with Metabolic Traits in Human White Adipose Tissue.

EBioMedicine 2018 Apr 15;30:248-260. Epub 2018 Mar 15.

Department of Medicine, Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183009
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http://dx.doi.org/10.1016/j.ebiom.2018.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952343PMC
April 2018

Long-Term Improvement in Aortic Pulse Wave Velocity After Weight Loss Can Be Predicted by White Adipose Tissue Factors.

Am J Hypertens 2018 03;31(4):450-457

Department of Medicine (H7), Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge, Stockholm, Sweden.

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https://academic.oup.com/ajh/article/31/4/450/4644826
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http://dx.doi.org/10.1093/ajh/hpx201DOI Listing
March 2018

The adipokine tartrate-resistant acid phosphatase 5a in serum correlates to adipose tissue expansion in obesity.

Biomarkers 2017 Dec 8;22(8):764-774. Epub 2017 Jun 8.

a Division of Pathology, Department of Laboratory Medicine , Karolinska Institutet, Karolinska University Hospital Huddinge , Stockholm , Sweden.

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https://www.tandfonline.com/doi/full/10.1080/1354750X.2017.1
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http://dx.doi.org/10.1080/1354750X.2017.1334155DOI Listing
December 2017

Quantitative high-content/high-throughput microscopy analysis of lipid droplets in subject-specific adipogenesis models.

Cytometry A 2017 11 14;91(11):1068-1077. Epub 2017 Oct 14.

Department of Information Technology Division of Visual Information and Interaction and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/cyto.a.23265DOI Listing
November 2017

Single cell transcriptomics suggest that human adipocyte progenitor cells constitute a homogeneous cell population.

Stem Cell Res Ther 2017 Nov 7;8(1):250. Epub 2017 Nov 7.

Karolinska Institutet, Lipid Laboratory, Department of Medicine Huddinge, Novum D4, Hälsovägen 7, 14186, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13287-017-0701-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678572PMC
November 2017

Improved glucose metabolism after gastric bypass: evolution of the paradigm.

Surg Obes Relat Dis 2016 Sep - Oct;12(8):1457-1465. Epub 2016 Mar 23.

Department of Surgery, Ersta Hospital, Stockholm, Sweden; Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.soard.2016.03.020DOI Listing
October 2017

The cell-type specific transcriptome in human adipose tissue and influence of obesity on adipocyte progenitors.

Sci Data 2017 10 31;4:170164. Epub 2017 Oct 31.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, Stockholm SE-14186, Sweden.

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http://www.nature.com/articles/sdata2017164
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http://dx.doi.org/10.1038/sdata.2017.164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663208PMC
October 2017

Subcutaneous Adipocyte Lipolysis Contributes to Circulating Lipid Levels.

Arterioscler Thromb Vasc Biol 2017 09 29;37(9):1782-1787. Epub 2017 Jun 29.

From the Department of Medicine, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm, Sweden.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.117.309759
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http://dx.doi.org/10.1161/ATVBAHA.117.309759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567402PMC
September 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Epigenetic Regulation of PLIN 1 in Obese Women and its Relation to Lipolysis.

Sci Rep 2017 08 31;7(1):10152. Epub 2017 Aug 31.

Department of Medicine, Huddinge, Karolinska Institutet, S-141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-017-09232-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578955PMC
August 2017

The contribution of bone marrow-derived cells to the human adipocyte pool.

Adipocyte 2017 07 15;6(3):187-192. Epub 2017 Mar 15.

a Karolinska Institutet , Department of Medicine (H7) , Karolinska University Hospital , Huddinge , Stockholm , Sweden.

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http://dx.doi.org/10.1080/21623945.2017.1306158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638374PMC
July 2017

CD36 Is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential.

Stem Cells 2017 07 18;35(7):1799-1814. Epub 2017 May 18.

Institut des Maladies Métaboliques et Cardiovasculaires, Team 1, INSERM and Université de Toulouse, Toulouse, Cedex, 4, France.

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http://dx.doi.org/10.1002/stem.2635DOI Listing
July 2017

Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women.

Am J Physiol Endocrinol Metab 2017 06 7;312(6):E482-E494. Epub 2017 Mar 7.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.1152/ajpendo.00251.2016DOI Listing
June 2017

Impact of fat mass and distribution on lipid turnover in human adipose tissue.

Nat Commun 2017 05 23;8:15253. Epub 2017 May 23.

Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm SE-141 86, Sweden.

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http://dx.doi.org/10.1038/ncomms15253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457499PMC
May 2017

Omentectomy in Addition to Bariatric Surgery-a 5-Year Follow-up.

Obes Surg 2017 04;27(4):1115-1118

Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s11695-017-2576-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339313PMC
April 2017

Long-term Protective Changes in Adipose Tissue After Gastric Bypass.

Diabetes Care 2017 Jan 16;40(1):77-84. Epub 2016 Nov 16.

Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.2337/dc16-1072DOI Listing
January 2017

Interplay between Obesity-Induced Inflammation and cGMP Signaling in White Adipose Tissue.

Cell Rep 2017 01;18(1):225-236

Institute of Pharmacology and Toxicology, University of Bonn, 53127 Bonn, Germany; Bonn International Graduate School of Drug Sciences, University of Bonn, 53127 Bonn, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247163171
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http://dx.doi.org/10.1016/j.celrep.2016.12.028DOI Listing
January 2017

The epigenetic signature of systemic insulin resistance in obese women.

Diabetologia 2016 11 18;59(11):2393-2405. Epub 2016 Aug 18.

Department of Medicine, Karolinska Institutet, Karolinska University Hospital, C2:94, Huddinge, S-141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00125-016-4074-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506095PMC
November 2016

Adipose and Circulating CCL18 Levels Associate With Metabolic Risk Factors in Women.

J Clin Endocrinol Metab 2016 Nov 26;101(11):4021-4029. Epub 2016 Jul 26.

Department of Medicine (H7) (D.E.H., P.P., J.B., I.D., J.L., J.A., A.E., A.K., N.M., D.P.A., P.A., M.R.), Karolinska Institutet, Stockholm, Sweden; Department of Biosciences and Nutrition (H.G.), Karolinska Institutet, Huddinge, Sweden; Department of Clinical Sciences (E.N.), Karolinska Institutet, Danderyd Hospital, Danderyd, Sweden.

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http://dx.doi.org/10.1210/jc.2016-2390DOI Listing
November 2016

Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity.

Diabetes 2016 10 18;65(10):2980-9. Epub 2016 Jul 18.

Lipid Laboratory, Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.2337/db16-0522DOI Listing
October 2016

Circulating and Adipose Levels of Adipokines Associated With Insulin Sensitivity in Nonobese Subjects With Type 2 Diabetes.

J Clin Endocrinol Metab 2016 10 8;101(10):3765-3771. Epub 2016 Aug 8.

Karolinska Institutet at Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2016-1883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052350PMC
October 2016

Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditions.

Mol Genet Metab 2016 09 23;119(1-2):174-85. Epub 2016 Jun 23.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, EH25 9RG, UK. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044862PMC
http://dx.doi.org/10.1016/j.ymgme.2016.06.009DOI Listing
September 2016

Datasets of genes coexpressed with FBN1 in mouse adipose tissue and during human adipogenesis.

Data Brief 2016 Sep 5;8:851-7. Epub 2016 Jul 5.

The Roslin Institute, University of Edinburgh, Easter Bush, EH25 9RG, UK.

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http://dx.doi.org/10.1016/j.dib.2016.06.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959917PMC
September 2016

The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.

Cell Rep 2016 08 18;16(9):2317-26. Epub 2016 Aug 18.

Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, 141 86 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.070DOI Listing
August 2016

Increased fat cell size: a major phenotype of subcutaneous white adipose tissue in non-obese individuals with type 2 diabetes.

Diabetologia 2016 Mar 25;59(3):560-70. Epub 2015 Nov 25.

Lipid laboratory, Novum, D4, Department of Medicine Huddinge, Karolinska Institutet, Hälsovägen 7, 14186, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00125-015-3810-6DOI Listing
March 2016

Numerous Genes in Loci Associated With Body Fat Distribution Are Linked to Adipose Function.

Diabetes 2016 Feb;65(2):433-7

Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.2337/db15-0828DOI Listing
February 2016

Effects of selected bioactive food compounds on human white adipocyte function.

Nutr Metab (Lond) 2016 19;13. Epub 2016 Jan 19.

Lipid Laboratory, Department of Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12986-016-0064-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717570PMC
January 2016

Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity.

Eur J Hum Genet 2015 Sep 19;23(9):1216-22. Epub 2014 Nov 19.

Department of Medicine (H7), Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/ejhg.2014.255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538196PMC
September 2015

MAFB as a novel regulator of human adipose tissue inflammation.

Diabetologia 2015 Sep 27;58(9):2115-23. Epub 2015 Jun 27.

Department of Medicine Huddinge, Lipid laboratory, Karolinska Institutet, Novum, NVS D4, Hälsovägen 7, 14186, Stockholm, Sweden.

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http://link.springer.com/10.1007/s00125-015-3673-x
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http://dx.doi.org/10.1007/s00125-015-3673-xDOI Listing
September 2015

MicroRNA-193b Controls Adiponectin Production in Human White Adipose Tissue.

J Clin Endocrinol Metab 2015 Aug 28;100(8):E1084-8. Epub 2015 May 28.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2015-1530DOI Listing
August 2015

Cidea improves the metabolic profile through expansion of adipose tissue.

Nat Commun 2015 Jun 29;6:7433. Epub 2015 Jun 29.

Department of Molecular Biosciences, Wenner-Gren Institute, Arrhenius Laboratories F3, Stockholm University, 106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1038/ncomms8433DOI Listing
June 2015

MicroRNA regulatory networks in human adipose tissue and obesity.

Nat Rev Endocrinol 2015 May 3;11(5):276-88. Epub 2015 Mar 3.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, SE-141 86 Stockholm, Sweden.

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http://www.nature.com/articles/nrendo.2015.25
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http://dx.doi.org/10.1038/nrendo.2015.25DOI Listing
May 2015

Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue.

Proc Natl Acad Sci U S A 2015 Apr 23;112(14):4363-8. Epub 2015 Mar 23.

Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;

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http://dx.doi.org/10.1073/pnas.1416412112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394244PMC
April 2015

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Authors:
Erik Arner Carsten O Daub Kristoffer Vitting-Seerup Robin Andersson Berit Lilje Finn Drabløs Andreas Lennartsson Michelle Rönnerblad Olga Hrydziuszko Morana Vitezic Tom C Freeman Ahmad M N Alhendi Peter Arner Richard Axton J Kenneth Baillie Anthony Beckhouse Beatrice Bodega James Briggs Frank Brombacher Margaret Davis Michael Detmar Anna Ehrlund Mitsuhiro Endoh Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley Forrester Daniel Goldowitz Reto Guler Thomas Ha Mitsuko Hara Meenhard Herlyn Tomokatsu Ikawa Chieko Kai Hiroshi Kawamoto Levon M Khachigian S Peter Klinken Soichi Kojima Haruhiko Koseki Sarah Klein Niklas Mejhert Ken Miyaguchi Yosuke Mizuno Mitsuru Morimoto Kelly J Morris Christine Mummery Yutaka Nakachi Soichi Ogishima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Xian-Yang Qin Sugata Roy Hiroki Sato Suzana Savvi Alka Saxena Anita Schwegmann Daisuke Sugiyama Rolf Swoboda Hiroshi Tanaka Andru Tomoiu Louise N Winteringham Ernst Wolvetang Chiyo Yanagi-Mizuochi Misako Yoneda Susan Zabierowski Peter Zhang Imad Abugessaisa Nicolas Bertin Alexander D Diehl Shiro Fukuda Masaaki Furuno Jayson Harshbarger Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Yuri Ishizu Masayoshi Itoh Tsugumi Kawashima Miki Kojima Naoto Kondo Marina Lizio Terrence F Meehan Christopher J Mungall Mitsuyoshi Murata Hiromi Nishiyori-Sueki Serkan Sahin Sayaka Nagao-Sato Jessica Severin Michiel J L de Hoon Jun Kawai Takeya Kasukawa Timo Lassmann Harukazu Suzuki Hideya Kawaji Kim M Summers Christine Wells David A Hume Alistair R R Forrest Albin Sandelin Piero Carninci Yoshihide Hayashizaki

Science 2015 Feb 12;347(6225):1010-4. Epub 2015 Feb 12.

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http://dx.doi.org/10.1126/science.1259418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681433PMC
February 2015

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome.

Am J Clin Nutr 2015 Jan 19;101(1):228-39. Epub 2014 Nov 19.

From the Institute of Public Health and Clinical Nutrition (MK, J Paananen, VdM, US, J Pihlajamäki, KSP, and MU) and the Institute of Biomedicine (CC), University of Eastern Finland, Kuopio, Finland; the Institute of Clinical Medicine, Clinical Nutrition (US and J Pihlajamäki) and Research Unit (MU), Kuopio University Hospital, Kuopio, Finland; the Department of Health, Nutrition and Management, Faculty of Health Sciences, Oslo, Norway, and Akershus University College of Applied Sciences, Oslo, Norway (SMU and MM); the Department of Medicine (H7), Karolinska Institute, Stockholm, Sweden (ID, PA, ED, and ES); the Unit for Nutrition Research, University of Iceland and Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland (IG and IT); Biomedical Nutrition, Pure and Applied Biochemistry, Lund University, Lund, Sweden (LC and BÅ); the Departments of Endocrinology (ML-O) and Clinical Nutrition (BÅ), Skåne University Hospital, Lund, Sweden; the Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden (FR and UR); the Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu, and Medical Research Center, Oulu University Hospital, Oulu, Finland (MJS and JH); University of Copenhagen, Faculty of Science, Department of Human Nutrition, Copenhagen, Denmark (LOD); Institute of Biomedicine, University of Oulu, Oulu, Finland (K-HH); the Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark (KH and LB); and VTT Technical Research Centre of Finland, Espoo, Finland (KSP).

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http://dx.doi.org/10.3945/ajcn.114.092783DOI Listing
January 2015

Omentectomy in addition to gastric bypass surgery and influence on insulin sensitivity: a randomized double blind controlled trial.

Clin Nutr 2014 Dec 12;33(6):991-6. Epub 2014 Jan 12.

Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2014.01.004DOI Listing
December 2014

Adipose tissue and metabolic alterations: regional differences in fat cell size and number matter, but differently: a cross-sectional study.

J Clin Endocrinol Metab 2014 Oct 17;99(10):E1870-6. Epub 2014 Jun 17.

Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2014-1526DOI Listing
October 2014

Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans.

Diabetes 2014 Jul 18;63(7):2356-68. Epub 2014 Feb 18.

Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden

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http://dx.doi.org/10.2337/db13-1622DOI Listing
July 2014

Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance.

Trends Endocrinol Metab 2014 May 11;25(5):255-62. Epub 2014 Apr 11.

Institut National de la Santé et de la Recherche Médicale (INSERM), Unité Mixte de Recherche (UMR) 1048, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases, 31432 Toulouse, France; University of Toulouse, UMR 1048, Paul Sabatier University, 31432 Toulouse, France; Toulouse University Hospitals, Department of Clinical Biochemistry, 31059 Toulouse, France.

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http://dx.doi.org/10.1016/j.tem.2014.03.002DOI Listing
May 2014

Additive effects of microRNAs and transcription factors on CCL2 production in human white adipose tissue.

Diabetes 2014 Apr 30;63(4):1248-58. Epub 2013 Dec 30.

Department of Medicine, Huddinge, Lipid Laboratory, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.2337/db13-0702DOI Listing
April 2014

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

MicroRNA profiling links miR-378 to enhanced adipocyte lipolysis in human cancer cachexia.

Am J Physiol Endocrinol Metab 2014 Feb 10;306(3):E267-74. Epub 2013 Dec 10.

Lipid Laboratory, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden;

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http://dx.doi.org/10.1152/ajpendo.00249.2013DOI Listing
February 2014

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.

Cell 2014 Jan;156(1-2):343-58

Chair of Nutritional Medicine, Technische Universität München, Else Kröner-Fresenius-Center for Nutritional Medicine, 85350 Freising-Weihenstephan, Germany; Nutritional Medicine Unit, ZIEL-Research Center for Nutrition and Food Sciences, Technische Universität München, 85350 Freising-Weihenstephan, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Clinical Cooperation Group Nutrigenomics and Type 2 Diabetes, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany and Technische Universität München, 85350 Freising-Weihenstephan, Germany; Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg 85764, Germany. Electronic address:

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http://www.cell.com/cms/attachment/2021778258/2041667086/mmc
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http://dx.doi.org/10.1016/j.cell.2013.10.058DOI Listing
January 2014

Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7.

Am J Physiol Endocrinol Metab 2013 Dec 8;305(11):E1359-66. Epub 2013 Oct 8.

Department of Physiology and Pharmacology, Section for Integrative Physiology, Karolinska Institutet, Stockholm, Sweden;

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http://ajpendo.physiology.org/cgi/doi/10.1152/ajpendo.00236.
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December 2013

Health and obesity: not just skin deep.

Science 2013 Nov;342(6158):558-9

Department of Medicine, Karolinska Institutet at Karolinska University Hospital, Huddinge, SE-141 86 Huddinge, Sweden.

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November 2013

Allograft inflammatory factor 1 (AIF-1) is a new human adipokine involved in adipose inflammation in obese women.

BMC Endocr Disord 2013 Nov 25;13:54. Epub 2013 Nov 25.

Department of Medicine Huddinge, Lipid Laboratory, Novum, Karolinska Institutet, Karolinska University Hospital, SE-141 86 Huddinge, Stockholm, Sweden.

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http://bmcendocrdisord.biomedcentral.com/articles/10.1186/14
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http://dx.doi.org/10.1186/1472-6823-13-54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175115PMC
November 2013

Adipocyte triglyceride turnover and lipolysis in lean and overweight subjects.

J Lipid Res 2013 Oct 30;54(10):2909-13. Epub 2013 Jul 30.

Department of Medicine Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.

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http://dx.doi.org/10.1194/jlr.M040345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770103PMC
October 2013

Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice.

Arterioscler Thromb Vasc Biol 2013 Jun 21;33(6):1189-96. Epub 2013 Mar 21.

Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1161/ATVBAHA.112.301105DOI Listing
June 2013

Variations in the size of the major omentum are primarily determined by fat cell number.

J Clin Endocrinol Metab 2013 May 29;98(5):E897-901. Epub 2013 Mar 29.

Karolinska Institutet, Department of Medicine, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2012-4106DOI Listing
May 2013

NPC1 in human white adipose tissue and obesity.

BMC Endocr Disord 2013 Jan 30;13. Epub 2013 Jan 30.

Department of Medicine Huddinge, Lipid Laboratory, Karolinska Institutet, 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1472-6823-13-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566954PMC
January 2013

Adipocyte triglyceride turnover is independently associated with atherogenic dyslipidemia.

J Am Heart Assoc 2012 Dec 19;1(6):e003467. Epub 2012 Dec 19.

Oxford Centre for Diabetes, Endocrinology & Metabolism, Churchill Hospital, Oxford, United Kingdom.

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https://www.ahajournals.org/doi/10.1161/JAHA.112.003467
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540680PMC
December 2012

Functional annotation of the human fat cell secretome.

Arch Physiol Biochem 2012 Jul 23;118(3):84-91. Epub 2012 May 23.

Karolinska Institutet, Department of Medicine, Huddinge, 141 86 Stockholm, Sweden.

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http://dx.doi.org/10.3109/13813455.2012.685745DOI Listing
July 2012