Peter Ainsworth

Peter Ainsworth

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Peter Ainsworth

Peter Ainsworth

Publications by authors named "Peter Ainsworth"

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Long term follow-up after liver transplantation from a mutation positive donor.

Hepatobiliary Surg Nutr 2019 Apr;8(2):189-191

Department of Surgery, Western University, London, ON, Canada.

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http://dx.doi.org/10.21037/hbsn.2019.01.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503249PMC
April 2019

Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Breast Cancer Res Treat 2018 Sep 17;171(2):421-426. Epub 2018 May 17.

Women's College Research Institute, Women's College Hospital, 76 Grenville St., 6th Floor, Toronto, ON, M5S 1B2, Canada.

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http://link.springer.com/10.1007/s10549-018-4822-y
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http://dx.doi.org/10.1007/s10549-018-4822-yDOI Listing
September 2018

Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation.

Gynecol Oncol 2018 07 21;150(1):85-91. Epub 2018 May 21.

Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2018.05.011DOI Listing
July 2018

Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues.

Front Oncol 2018 23;8:100. Epub 2018 Apr 23.

Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.

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http://dx.doi.org/10.3389/fonc.2018.00100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925605PMC
April 2018

Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes.

Am J Hum Genet 2018 01;102(1):156-174

Department of Pathology and Laboratory Medicine, Western University, London, ON N6A5C1, Canada; Molecular Genetics Laboratory, Molecular Diagnostics Division, London Health Sciences Centre, London, ON N6A5W9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777983PMC
January 2018

Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders.

J Mol Diagn 2017 11 12;19(6):848-856. Epub 2017 Aug 12.

Department of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada; Molecular Genetics Laboratory, Molecular Diagnostics Division, London Health Sciences Centre, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.07.002DOI Listing
November 2017

Clinical Validation of Copy Number Variant Detection from Targeted Next-Generation Sequencing Panels.

J Mol Diagn 2017 11 15;19(6):905-920. Epub 2017 Aug 15.

Molecular Genetics Laboratory, Molecular Diagnostics Division, London Health Sciences Centre, London, Ontario, Canada; Department of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.07.004DOI Listing
November 2017

Genetics Consultation Rates Following a Diagnosis of High-Grade Serous Ovarian Carcinoma in the Canadian Province of Ontario.

Int J Gynecol Cancer 2017 03;27(3):437-443

*Division of Gynecologic Oncology, Victoria Hospital; †Department of Obstetrics and Gynecology, Western University; ‡Institute for Clinical Evaluative Sciences-Western Satellite Site (ICES Western); §Department of Medical Genetics, Victoria Hospital; and ∥Department of Molecular Genetics, Western University, London; and ¶Division of Gynecologic Oncology, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1097/IGC.0000000000000907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427985PMC
March 2017

Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors.

J Pediatr Genet 2017 Mar 8;6(1):30-41. Epub 2016 Nov 8.

Department of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada; London Regional Cancer Program, London Health Sciences Centre, London, Ontario, Canada; Children's Health Research Institute, London, Ontario, Canada.

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http://dx.doi.org/10.1055/s-0036-1593849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288004PMC
March 2017

Relationship between Caffeine and Levels of DNA Repair and Oxidative Stress in Women with and without a BRCA1 Mutation.

J Nutrigenet Nutrigenomics 2015 16;8(4-6):174-84. Epub 2015 Dec 16.

Women's College Research Institute, Women's College Hospital, Toronto, Ont., Canada.

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http://dx.doi.org/10.1159/000439110DOI Listing
December 2016

The defining DNA methylation signature of Floating-Harbor Syndrome.

Sci Rep 2016 12 9;6:38803. Epub 2016 Dec 9.

Department of Pathology and Laboratory Medicine, Western University, 1151 Richmond Street, London, N6A 3K7, Canada.

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http://dx.doi.org/10.1038/srep38803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146968PMC
December 2016

DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.

Crit Rev Clin Lab Sci 2016 12;53(3):147-65. Epub 2016 Jan 12.

a Departments of Pathology and Laboratory Medicine .

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http://dx.doi.org/10.3109/10408363.2015.1113496DOI Listing
November 2016

Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.

J Mol Diagn 2016 11 29;18(6):834-841. Epub 2016 Aug 29.

Department of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada; London Regional Cancer Program, London Health Sciences Center, London, Ontario, Canada; Children's Health Research Institute, London Health Sciences Center, London, Ontario, Canada; Molecular Genetics Laboratory, London Health Sciences Center, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.06.005DOI Listing
November 2016

Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis.

J Mol Diagn 2016 09 2;18(5):657-667. Epub 2016 Jul 2.

Department of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada; Molecular Genetics Laboratory, Molecular Diagnostics Division, London Health Sciences Centre, Children's Health Research Institute, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.04.002DOI Listing
September 2016

Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia.

Eur J Haematol 2016 Apr 3;96(4):360-6. Epub 2015 Jul 3.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1111/ejh.12597DOI Listing
April 2016

Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation.

Fertil Steril 2016 Mar 14;105(3):781-785. Epub 2015 Dec 14.

Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.fertnstert.2015.11.034DOI Listing
March 2016

Weight gain after oophorectomy among women with a BRCA1 or BRCA2 mutation.

Womens Health (Lond) 2015 Jul 10;11(4):453-9. Epub 2015 Aug 10.

Women's College Research Institute, 790 Bay Street, Room 750, Toronto, ON, M5G 1N8, Canada.

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http://dx.doi.org/10.2217/WHE.15.4DOI Listing
July 2015

Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation.

J Clin Oncol 2014 May 24;32(15):1547-53. Epub 2014 Feb 24.

Amy P.M. Finch, Barry Rosen, Andrea Eisen, Kelly A. Metcalfe, Islay Thompson, Joan Murphy, Ping Sun, and Steven A. Narod, University of Toronto; Barry Rosen and Joan Murphy, Princess Margaret Hospital; Amy P.M. Finch, Islay Thompson, Ping Sun, and Steven A. Narod, Women's College Research Institute; Andrea Eisen, Sunnybrook Odette Cancer Center, Toronto; Peter Ainsworth, London Regional Cancer Program, London, Ontario; Parviz Ghadirian, University of Montreal Hospital Centre; William D. Foulkes, McGill University, Montreal, Quebec; Charmaine Kim-Sing, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Jan Lubinski, Cezary Cybulski, and Tomasz Huzarski, Pomeranian Medical University, Szczecin, Poland; Pål Møller and Lovise Maehle, Norwegian Radium Hospital and Oslo University Hospital, Oslo, Norway; Christian F. Singer, Medical University of Vienna, Vienna, Austria; Beth Karlan, Cedars-Sinai Medical Center, Beverly Hills; Susan Neuhausen, City of Hope National Medical Center, Duarte, CA; Leigha Senter, Ohio State University Medical Center, Columbus, OH; Nadine Tung, Beth Israel Deaconess Medical Center, Boston, MA; and Henry T. Lynch, Creighton University School of Medicine, Omaha, NE.

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http://dx.doi.org/10.1200/JCO.2013.53.2820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026578PMC
May 2014

Chemotherapy-induced amenorrhea in patients with breast cancer with a BRCA1 or BRCA2 mutation.

J Clin Oncol 2013 Nov 26;31(31):3914-9. Epub 2013 Aug 26.

Adriana Valentini, Amy Finch, Ping Sun, and Steven A. Narod, Women's College Research Institute; Ellen Greenblatt, Centre for Fertility and Reproductive Health, Mount Sinai Hospital, University of Toronto, Toronto; Peter J. Ainsworth, London Regional Cancer Program, London, Ontario; Parviz Ghadirian, Research Center of the University of Montreal Hospital Centre, Montreal, Quebec; Charmaine Kim-Sing, BC Cancer Agency, Vancouver, British Columbia, Canada; Henry T. Lynch, Creighton University School of Medicine, Omaha, NE; Susan L. Neuhausen, Beckman Research Institute, City of Hope, Duarte, CA; Jan Lubiński and Tomasz Byrski, Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland; and Christian Singer, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1200/JCO.2012.47.7893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805929PMC
November 2013

The impact of population-based screening studies on hemochromatosis screening practices.

Dig Dis Sci 2012 May;57(5):1420-2

Department of Medicine, University Hospital, University of Western Ontario, 339 Windermere Rd, London, ON N6A 5A5, Canada.

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http://dx.doi.org/10.1007/s10620-011-2001-7DOI Listing
May 2012

Recognizing BRCA gene mutation risk subsequent to breast cancer diagnosis in southwestern Ontario.

Can Fam Physician 2012 May;58(5):e258-66

University of Western Ontario, Health Professional Education, Elborn College, Room 2538, 1151 Richmond St, London, ON N6G 1N1, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352812PMC
May 2012

Comprehensive prediction of mRNA splicing effects of BRCA1 and BRCA2 variants.

Hum Mutat 2011 Jul 5;32(7):735-42. Epub 2011 May 5.

Department of Biochemistry, SchulichSchool of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1002/humu.21513DOI Listing
July 2011

Toenail selenium status and DNA repair capacity among female BRCA1 mutation carriers.

Cancer Causes Control 2010 May 9;21(5):679-87. Epub 2010 Jan 9.

Women's College Research Institute, 790 Bay Street, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s10552-009-9495-8DOI Listing
May 2010

A BRCA1 mutation is not associated with increased indicators of oxidative stress.

Clin Breast Cancer 2008 Dec;8(6):506-10

Women's College Research Institute, Women's College Hospital, Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.3816/CBC.2008.n.061DOI Listing
December 2008

Novel 95G>A (R32K) somatic mosaic connexin 32 mutation.

Muscle Nerve 2008 Nov;38(5):1510-1514

Department of Pathology, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1002/mus.21145DOI Listing
November 2008

Colonic interposition in a woman with attenuated familial adenomatosis polyposis: does the location of the colon affect polyp formation?

Can J Gastroenterol 2008 Jul;22(7):634-6

Department of Medicine, Division of Gastroentergology, University of Western Ontario, London, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661270PMC
http://dx.doi.org/10.1155/2008/780204DOI Listing
July 2008

A burning desire to understand genetic mutations in gastroenterology.

Authors:
Peter Ainsworth

Can J Gastroenterol 2006 Oct;20(10):629-30

Department of Biochemistry, University of Western Ontario, London, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660787PMC
http://dx.doi.org/10.1155/2006/815307DOI Listing
October 2006

Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.

Int J Cancer 2006 Jan;118(1):103-7

Epidemiology Research Unit, Research Centre, Centre Hospitalier de 'Universitaire de Montréal, CHUM Hôtel-Dieu, Montréal, Canada.

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http://dx.doi.org/10.1002/ijc.21296DOI Listing
January 2006

Hormone replacement therapy and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.

Gynecol Oncol 2006 Jan 31;100(1):83-8. Epub 2005 Aug 31.

Centre for Research in Women's Health, 790 Bay Street, 7th Floor, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada M5G 1N8.

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http://dx.doi.org/10.1016/j.ygyno.2005.07.110DOI Listing
January 2006

Smoking and the risk of breast cancer among carriers of BRCA mutations.

Int J Cancer 2004 Jun;110(3):413-6

Epidemiology Research Unit, Centre Hospitalier del'Universite de Montreal Hotel-Dieu, Faculty of Medicine, Université de Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ijc.20106DOI Listing
June 2004

Alternatively spliced, truncated human BRCA2 isoforms contain a novel coding exon.

Eur J Hum Genet 2003 Dec;11(12):951-4

Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1038/sj.ejhg.5201063DOI Listing
December 2003

Genotype/Phenotype Correlations in X-Linked Dominant Charcot-Marie-Tooth Disease.

Ann N Y Acad Sci 1999 Oct;883(1):366-382

Department of Clinical Neurological Sciences, London Health Sciences Centre and The University of Western Ontario, London, Canada N6A 5A5Department of Neurological Sciences, Foothills Hospital and The University of Calgary, Alberta, CanadaDepartment of Neurology, New England Medical Center, Boston, Massachusetts, USADepartment of Biochemistry, London Health Sciences Centre and The Univeristy of Western Ontario, London, Canada N6A 5A5.

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http://dx.doi.org/10.1111/j.1749-6632.1999.tb08598.xDOI Listing
October 1999