Publications by authors named "Peter Aichele"

40Publications

NK1.1 innate lymphoid cells in salivary glands inhibit establishment of tissue-resident memory CD8 T cells in mice.

Eur J Immunol 2020 Jul 31. Epub 2020 Jul 31.

Institute for Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.202048741DOI Listing
July 2020

Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis.

Eur J Immunol 2020 May 17. Epub 2020 May 17.

Center for Chronic Immunodeficiency (CCI), Faculty of Medicine, Institute for Immunodeficiency, Medical Center, University of Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.201948123DOI Listing
May 2020

Retroviral Gene Transfer Restores Cytotoxic Activity of T Cells Derived from Familial Hemophagocytic Lymphohistiocytosis Type 3 Patients .

Hum Gene Ther 2019 08 21;30(8):975-984. Epub 2019 May 21.

1Institute for Transfusion Medicine and Gene Therapy, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1089/hum.2019.025DOI Listing
August 2019

Regulatory T cells characterized by low Id3 expression are highly suppressive and accumulate during chronic infection.

Oncotarget 2017 Nov 27;8(61):102835-102851. Epub 2017 Oct 27.

Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.

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http://dx.doi.org/10.18632/oncotarget.22159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732693PMC
November 2017

Immunological phenotype of the murine Lrba knockout.

Immunol Cell Biol 2017 10 25;95(9):789-802. Epub 2017 Jul 25.

Center for Chronic Immunodeficiency (CCI), Medical Center-Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/icb.2017.52DOI Listing
October 2017

Id3 Controls Cell Death of 2B4+ Virus-Specific CD8+ T Cells in Chronic Viral Infection.

J Immunol 2015 Sep 31;195(5):2103-14. Epub 2015 Jul 31.

Center for Chronic Immunodeficiency, University Medical Center and University of Freiburg, 79106 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79106 Freiburg, Germany;

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http://dx.doi.org/10.4049/jimmunol.1402607DOI Listing
September 2015

T cell expansion is the limiting factor of virus control in mice with attenuated TCR signaling: implications for human immunodeficiency.

J Immunol 2015 Mar 11;194(6):2725-34. Epub 2015 Feb 11.

Center for Chronic Immunodeficiency, University Medical Center Freiburg and University of Freiburg, 79106 Freiburg, Germany;

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http://dx.doi.org/10.4049/jimmunol.1400328DOI Listing
March 2015

Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice.

Circulation 2014 Jun 24;129(23):2414-25. Epub 2014 Mar 24.

From the Atherogenesis Research Group, University Heart Center (D.W., F.J., N.A.M., E.N.B., N.H., B.D., A.O.R., C.C., L.N., B.R., A.W., L.S., A.P., A.L., S.P.H., P.S., I.H., F.W., C.v.z.M., C.B., A.Z.) and Institute for Medical Microbiology and Hygiene, Department of Immunology (P.A.), University of Freiburg, Freiburg, Germany; Atherothrombosis and Vascular Biology (F.J., J.R., Y.C.C., C.C., N.B., K.P.) and Cellular and Molecular Metabolism (M.A.F.), Baker IDI Heart and Diabetes Institute, Melbourne, Australia; Department of Diagnostic Radiology Medical Physics, University Hospital Freiburg, Freiburg, Germany (D.v.E.); Department of Laboratory Medicine, Medical University of Vienna and Center for Molecular Medicine, Austrian Academy of Sciences, Vienna, Austria (C.J.B.); Division of Cardiovascular Sciences, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain (N.V.); and Brigham and Women's Hospital, Cardiovascular Medicine, Harvard Medical School, Boston, MA (P.L.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.008055DOI Listing
June 2014

Helicobacter pylori protects oncogenically transformed cells from reactive oxygen species-mediated intercellular induction of apoptosis.

Carcinogenesis 2014 Jul 24;35(7):1582-91. Epub 2014 Mar 24.

Institute of Microbiology, Department of Medical Microbiology and Hygiene, University Medical Center, Freiburg D-79104, Germany.

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http://dx.doi.org/10.1093/carcin/bgu074DOI Listing
July 2014

Graded defects in cytotoxicity determine severity of hemophagocytic lymphohistiocytosis in humans and mice.

Front Immunol 2013 16;4:448. Epub 2013 Dec 16.

Centre of Chronic Immunodeficiency, University Medical Center Freiburg, University of Freiburg , Freiburg , Germany.

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http://dx.doi.org/10.3389/fimmu.2013.00448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864253PMC
December 2013

Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease.

Blood 2013 Jan 27;121(4):604-13. Epub 2012 Nov 27.

Institute for Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-07-44
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http://dx.doi.org/10.1182/blood-2012-07-441139DOI Listing
January 2013

Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota.

Immunity 2012 Jul 28;37(1):171-86. Epub 2012 Jun 28.

IMMH, Institute of Medical Microbiology and Hygiene, University of Freiburg, Hermann-Herder-Strasse 11, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.immuni.2012.05.020DOI Listing
July 2012

Signal 3 requirement for memory CD8+ T-cell activation is determined by the infectious pathogen.

Eur J Immunol 2011 Nov 26;41(11):3176-86. Epub 2011 Sep 26.

Institute for Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.201141537DOI Listing
November 2011

T cells acquire cell surface determinants of APC via in vivo trogocytosis during viral infections.

Eur J Immunol 2010 Dec;40(12):3450-7

Institute for Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.201040743DOI Listing
December 2010

Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.

Cancer Cell 2010 Mar;17(3):262-72

Charité - Universitätsmedizin Berlin/Molekulares Krebsforschungszentrum der Charité - MKFZ, 13353 Berlin, Germany.

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http://dx.doi.org/10.1016/j.ccr.2009.12.043DOI Listing
March 2010

Studying NK cell/dendritic cell interactions.

Methods Mol Biol 2010 ;612:97-126

Institute of Medical Microbiology & Hygiene, University of Freiburg Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-1-60761-362-6_8DOI Listing
February 2010

Effector T-cell differentiation during viral and bacterial infections: Role of direct IL-12 signals for cell fate decision of CD8(+) T cells.

Eur J Immunol 2009 Jul;39(7):1774-83

Institute for Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.200839093DOI Listing
July 2009

Analysis of CD8+ T-cell-mediated inhibition of hepatitis C virus replication using a novel immunological model.

Gastroenterology 2009 Apr 13;136(4):1391-401. Epub 2008 Dec 13.

Department of Medicine II, University Hospital Freiburg, and Faculty of Biology, Spemann Graduate School of Biology and Medicine, Albert Ludwigs University, Freiburg, Germany.

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http://dx.doi.org/10.1053/j.gastro.2008.12.034DOI Listing
April 2009

The elimination of Anaplasma phagocytophilum requires CD4+ T cells, but is independent of Th1 cytokines and a wide spectrum of effector mechanisms.

Eur J Immunol 2008 Dec;38(12):3395-410

Department of Medical Microbiology and Hygiene, Institute of Medical Microbiology and Hygiene, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.200838615DOI Listing
December 2008

Analysis of direct and cross-presentation of antigens in TPPII knockout mice.

J Immunol 2007 Dec;179(12):8137-45

Clinic for Radiotherapy, University Hospital of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.4049/jimmunol.179.12.8137DOI Listing
December 2007

Dendritic cells prime natural killer cells by trans-presenting interleukin 15.

Immunity 2007 Apr 29;26(4):503-17. Epub 2007 Mar 29.

Skirball Institute of Biomolecular Medicine, Program in Molecular Pathogenesis, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.immuni.2007.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2084390PMC
April 2007

CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion.

J Immunol 2006 Apr;176(8):4525-9

Institute for Medical Microbiology and Hygiene, Department of Immunology, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.4049/jimmunol.176.8.4525DOI Listing
April 2006

Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoire.

J Clin Invest 2006 Jan;116(1):156-62

Institute of Experimental Immunology, Department of Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1172/JCI26565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1323267PMC
January 2006

Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection.

J Infect Dis 2003 Nov 28;188(9):1326-31. Epub 2003 Oct 28.

Max-Planck-Institut für Infektionsbiologie, Berlin, Germany.

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http://dx.doi.org/10.1086/378563DOI Listing
November 2003