Peter A C 't Hoen

Peter A C 't Hoen

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Peter A C 't Hoen

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Increasing phenotypic annotation improves the diagnostic rate of exome sequencing in a rare neuromuscular disorder.

Hum Mutat 2019 Jun 23. Epub 2019 Jun 23.

Centro Nacional de Análisis Genómico (CNAG-CRG), Center for Genomic Regulation, Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.

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http://dx.doi.org/10.1002/humu.23792DOI Listing
June 2019

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine.

Neurology 2019 Apr 3;92(16):e1899-e1911. Epub 2019 Apr 3.

From the Departments of Neurology (G.L.J.O., J.A.P., D.A.K., R.Z., I.d.B., M.D.F., G.M.T., A.M.J.M.v.d.M.), Human Genetics (A.D., L.S.V., P.A.C.'tH., A.M.J.M.v.d.M.), Molecular Epidemiology (M.B., P.E.S.), Radiology (D.A.K.), and Medical Statistics (J.J.G.), Leiden University Medical Centre; Department of Biological Psychology (L.L., R.P., D.I.B.), Vrije Universiteit Amsterdam; Amsterdam Public Health Institute (L.L.); Amsterdam Neuroscience and Amsterdam Public Health (M.B., C.S.T., Y.M., D.I.B., B.W.P.); Department of Psychiatry (M.B., C.S.T., Y.M., B.W.P.), VU University Medical Centre/GGZ inGeest, Amsterdam; Departments of Epidemiology (A.D., J.L., K.-x.W., N.A., M.A.I., C.M.v.D.) and Neurology (M.A.I.), Erasmus Medical Centre, Rotterdam; Departments of Genetics (J.F., L.F., C.W.) and Pediatrics (J.F.), University Medical Centre Groningen; Department of Internal Medicine (C.J.H.v.d.K., F.H.M.V., M.M.J.v.G., M.T.S., C.D.A.S.) and Heart and Vascular Center (M.T.S.), Maastricht University Medical Centre; CARIM School for Cardiovascular Diseases (C.J.H.v.d.K., M.M.J.v.G., I.C.W.A., M.T.S., P.C.D., C.D.A.S.), Department of Epidemiology (I.C.W.A.), MaCSBio Maastricht Centre for Systems Biology (I.C.W.A.), and Department of Epidemiology (P.C.D.), Maastricht University; Department of Radiology (M.A.I.), Erasmus MC University Medical Centre, Rotterdam; Leiden Academic Centre in Drug Research, Faculty Science (C.M.v.D.), Leiden University; and Centre for Molecular and Biomolecular Informatics (P.A.C.'tH.), Radboud University Medical Centre Nijmegen, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000007313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550500PMC
April 2019

Strap associates with Csde1 and affects expression of select Csde1-bound transcripts.

PLoS One 2018 23;13(8):e0201690. Epub 2018 Aug 23.

Sanquin Research, Department of Hematopoiesis, and Landsteiner Laboratory Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201690PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107111PMC
February 2019

Computational approaches for the analysis of RNA-protein interactions: A primer for biologists.

J Biol Chem 2019 01 19;294(1):1-9. Epub 2018 Nov 19.

the Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands

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http://www.jbc.org/lookup/doi/10.1074/jbc.REV118.004842
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http://dx.doi.org/10.1074/jbc.REV118.004842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322881PMC
January 2019

Comparative transcriptomics of shear stress treated Pkd1 cells and pre-cystic kidneys reveals pathways involved in early polycystic kidney disease.

Biomed Pharmacother 2018 Dec 1;108:1123-1134. Epub 2018 Oct 1.

Department of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322183272
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http://dx.doi.org/10.1016/j.biopha.2018.07.178DOI Listing
December 2018

Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells.

Cell Mol Life Sci 2018 Oct 28;75(20):3857-3875. Epub 2018 May 28.

Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00018-018-2842-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154026PMC
October 2018

The distinct transcriptomes of slow and fast adult muscles are delineated by noncoding RNAs.

FASEB J 2018 03 3;32(3):1579-1590. Epub 2018 Jan 3.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1096/fj.201700861RDOI Listing
March 2018

Dysfunctional transcripts are formed by alternative polyadenylation in OPMD.

Oncotarget 2017 Sep 5;8(43):73516-73528. Epub 2017 Sep 5.

Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.20640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278PMC
September 2017

Drug Repositioning through Systematic Mining of Gene Coexpression Networks in Cancer.

PLoS One 2016 8;11(11):e0165059. Epub 2016 Nov 8.

A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165059PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100910PMC
June 2017

Meta-analysis of polycystic kidney disease expression profiles defines strong involvement of injury repair processes.

Am J Physiol Renal Physiol 2017 04 1;312(4):F806-F817. Epub 2017 Feb 1.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands; and

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http://www.physiology.org/doi/10.1152/ajprenal.00653.2016
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http://dx.doi.org/10.1152/ajprenal.00653.2016DOI Listing
April 2017

An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites.

NPJ Aging Mech Dis 2017 7;3. Epub 2017 Apr 7.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41514-017-0007-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445584PMC
April 2017

Identifying a gene expression signature of cluster headache in blood.

Sci Rep 2017 01 11;7:40218. Epub 2017 Jan 11.

Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/srep40218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225606PMC
January 2017

Non-sequential and multi-step splicing of the dystrophin transcript.

RNA Biol 2016 15;13(3):290-305. Epub 2015 Dec 15.

a Department of Human Genetics , Leiden University Medical Center , Leiden , the Netherlands.

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http://dx.doi.org/10.1080/15476286.2015.1125074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829307PMC
December 2016

Repeated FcεRI triggering reveals modified mast cell function related to chronic allergic responses in tissue.

J Allergy Clin Immunol 2016 09 28;138(3):869-880. Epub 2016 Mar 28.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.01.017DOI Listing
September 2016

Common disease signatures from gene expression analysis in Huntington's disease human blood and brain.

Orphanet J Rare Dis 2016 08 1;11(1):97. Epub 2016 Aug 1.

Department of Human Genetics, Leiden University Medical Center, PO Box 9600, Leiden, 2300 RC, The Netherlands.

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http://dx.doi.org/10.1186/s13023-016-0475-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968014PMC
August 2016

Consistency of biological networks inferred from microarray and sequencing data.

BMC Bioinformatics 2016 Jun 24;17:254. Epub 2016 Jun 24.

Leiden University Medical Center, Leiden University, Leiden, The Netherlands.

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http://dx.doi.org/10.1186/s12859-016-1136-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919861PMC
June 2016

Comparative mass spectrometric and immunoassay-based proteome analysis in serum of Duchenne muscular dystrophy patients.

Proteomics Clin Appl 2016 Mar 8;10(3):290-9. Epub 2016 Jan 8.

Center for Proteomics and Metabolomics, Leiden University Medical Center (LUMC), Leiden, The Netherlands.

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http://dx.doi.org/10.1002/prca.201500044DOI Listing
March 2016

SplicePie: a novel analytical approach for the detection of alternative, non-sequential and recursive splicing.

Nucleic Acids Res 2015 Jul 23;43(12):e80. Epub 2015 Mar 23.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands Leiden Genome Technology Center, Leiden University Medical Center, Leiden, The Netherlands

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkv242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499118PMC
July 2015

Response to: Evaluation of the serum matrix metalloproteinase-9 as a biomarker for monitoring disease progression in Duchenne muscular dystrophy.

Neuromuscul Disord 2015 May 23;25(5):446-7. Epub 2015 Feb 23.

Department of Human Genetics, Leiden University Medical Center, Postzone S4-P, P.O. Box 9600, Leiden 2300 RC, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2015.02.011DOI Listing
May 2015

Assessing the translational landscape of myogenic differentiation by ribosome profiling.

Nucleic Acids Res 2015 May 14;43(9):4408-28. Epub 2015 Apr 14.

Department of Human Genetics, Leiden University Medical Center, Postzone S4-P, PO Box 9600, 2300 RC Leiden, The Netherlands

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http://dx.doi.org/10.1093/nar/gkv281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482065PMC
May 2015

Alternative mRNA transcription, processing, and translation: insights from RNA sequencing.

Trends Genet 2015 Mar 30;31(3):128-39. Epub 2015 Jan 30.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2015.01.001DOI Listing
March 2015

204th ENMC International Workshop on Biomarkers in Duchenne Muscular Dystrophy 24-26 January 2014, Naarden, The Netherlands.

Neuromuscul Disord 2015 Feb 11;25(2):184-98. Epub 2014 Sep 11.

Department of Medicine, Department of Human Genetics, The University of Chicago, USA.

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http://dx.doi.org/10.1016/j.nmd.2014.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534085PMC
February 2015

Myostatin/activin blocking combined with exercise reconditions skeletal muscle expression profile of mdx mice.

Mol Cell Endocrinol 2015 Jan 7;399:131-42. Epub 2014 Oct 7.

Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, Rautpohjankatu 8, P.O. Box 35, Jyväskylä FI-40014, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.10.001DOI Listing
January 2015

Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses.

PLoS Genet 2015 Jan 8;11(1):e1004835. Epub 2015 Jan 8.

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands; Department of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1004835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287344PMC
January 2015

Roux-en-Y gastric bypass surgery, but not calorie restriction, reduces plasma branched-chain amino acids in obese women independent of weight loss or the presence of type 2 diabetes.

Diabetes Care 2014 Dec 14;37(12):3150-6. Epub 2014 Oct 14.

Department of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, the Netherlands Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands Einthoven Laboratory for Experimental Vascular Medicine, Leiden, the Netherlands.

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http://dx.doi.org/10.2337/dc14-0195DOI Listing
December 2014

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

Am J Physiol Endocrinol Metab 2014 Nov 23;307(10):E885-95. Epub 2014 Sep 23.

Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands

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http://dx.doi.org/10.1152/ajpendo.00215.2014DOI Listing
November 2014

Genetics of the human metabolome, what is next?

Biochim Biophys Acta 2014 Oct 4;1842(10):1923-1931. Epub 2014 Jun 4.

Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands; Department of Endocrinology, Leiden University Medical Center, Leiden, Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439140015
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http://dx.doi.org/10.1016/j.bbadis.2014.05.030DOI Listing
October 2014

RNA sequencing: from tag-based profiling to resolving complete transcript structure.

Cell Mol Life Sci 2014 Sep 15;71(18):3537-51. Epub 2014 May 15.

Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00018-014-1637-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143603PMC
September 2014

Joint modeling of ChIP-seq data via a Markov random field model.

Biostatistics 2014 Apr 30;15(2):296-310. Epub 2013 Oct 30.

School of Information Systems, Computing and Mathematics, Brunel University, London UB8 3PH, UK.

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http://dx.doi.org/10.1093/biostatistics/kxt047DOI Listing
April 2014

Fibronectin is a serum biomarker for Duchenne muscular dystrophy.

Proteomics Clin Appl 2014 Apr 11;8(3-4):269-78. Epub 2014 Mar 11.

Department of Human Genetics, Leiden University Medical Center (LUMC), RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/prca.201300072DOI Listing
April 2014

RNA expression profiling in brains of familial hemiplegic migraine type 1 knock-in mice.

Cephalalgia 2014 Mar 28;34(3):174-82. Epub 2013 Aug 28.

Department of Human Genetics, Leiden University Medical Centre, The Netherlands.

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http://dx.doi.org/10.1177/0333102413502736DOI Listing
March 2014

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

PhD7Faster: predicting clones propagating faster from the Ph.D.-7 phage display peptide library.

J Bioinform Comput Biol 2014 Feb 21;12(1):1450005. Epub 2014 Jan 21.

Center of Bioinformatics (COBI), Key Laboratory for NeuroInformation of Ministry of Education, University of Electronic Science and Technology of China, Chengdu 610054, P. R. China.

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http://dx.doi.org/10.1142/S021972001450005XDOI Listing
February 2014

DMD transcript imbalance determines dystrophin levels.

FASEB J 2013 Dec 23;27(12):4909-16. Epub 2013 Aug 23.

1Department of Human Genetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1096/fj.13-232025DOI Listing
December 2013

Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories.

Nat Biotechnol 2013 Nov 15;31(11):1015-22. Epub 2013 Sep 15.

1] Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. [2] Netherlands Bioinformatics Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/nbt.2702DOI Listing
November 2013

Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions.

Nucleic Acids Res 2013 Aug 14;41(15):e146. Epub 2013 Jun 14.

Center for Human and Clinical Genetics and Leiden University Medical Center, Leiden Genome Technology Center, Leiden University Medical Center, Einthovenweg 20, 2300 ZC Leiden, The Netherlands, Netherlands Bioinformatics Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands, Department of Epidemiology and Biostatistics, VU University Medical Center, De Boelelaan 1118, 1081 HZ Amsterdam, The Netherlands and Department of Pediatric Oncology, Erasmus Medical Center - Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkt525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753644PMC
August 2013

Accounting for immunoprecipitation efficiencies in the statistical analysis of ChIP-seq data.

BMC Bioinformatics 2013 May 30;14:169. Epub 2013 May 30.

School of Information Systems, Computing and Mathematics, Brunel University, London, UK.

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http://dx.doi.org/10.1186/1471-2105-14-169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717085PMC
May 2013

Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy.

Cell Mol Life Sci 2013 Feb 4;70(3):407-23. Epub 2012 Jul 4.

Department of Molecular Cell Biology and Centre for Biomedical Genetics, Leiden University Medical Centre, Building 2, Room R-02-022, Postzone S-1-P, PO Box 9600, Einthovenweg 20, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00018-012-1054-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541930PMC
February 2013

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions.

Nucleic Acids Res 2012 Oct 19;40(18):9272-85. Epub 2012 Jul 19.

Department of Biochemistry & Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/nar/gks658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467056PMC
October 2012

Exploring the transcriptome of ciliated cells using in silico dissection of human tissues.

PLoS One 2012 25;7(4):e35618. Epub 2012 Apr 25.

A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035618PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338421PMC
September 2012

Fcγ receptor IIb strongly regulates Fcγ receptor-facilitated T cell activation by dendritic cells.

J Immunol 2012 Jul 30;189(1):92-101. Epub 2012 May 30.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1103703
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http://dx.doi.org/10.4049/jimmunol.1103703DOI Listing
July 2012

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.

J Clin Invest 2012 Jul 18;122(7):2519-30. Epub 2012 Jun 18.

Department of Anatomy, Embryology, and Physiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1172/JCI62613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386824PMC
July 2012

T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells.

Cardiovasc Res 2012 Jun 14;94(3):439-49. Epub 2012 Mar 14.

Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Meibergdreef 15, Room L2-108, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvs120DOI Listing
June 2012

Cell-type specific regulation of myostatin signaling.

FASEB J 2012 Apr 27;26(4):1462-72. Epub 2011 Dec 27.

Center for Human and Clinical Genetics, Leiden University Medical Center, Postzone S4-P, PO Box 9600, 2300RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1096/fj.11-191189DOI Listing
April 2012

Phage display screening without repetitious selection rounds.

Anal Biochem 2012 Feb 13;421(2):622-31. Epub 2011 Nov 13.

Center for Human and Clinical Genetics and Leiden Genome Technology Center, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.ab.2011.11.005DOI Listing
February 2012

PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data.

Bioinformatics 2012 Feb 4;28(4):479-86. Epub 2012 Jan 4.

Department of Molecular Epidemiology, Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/btr712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278765PMC
February 2012

Increased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA.

BMC Genomics 2012 Jan 18;13:28. Epub 2012 Jan 18.

Center for Human and Clinical Genetics, Leiden University Medical Center, Einthovenweg 20, 2333ZC, Leiden, The Netherlands.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-13-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275489PMC
January 2012