Publications by authors named "Perry M Elliott"

100Publications

Identification of a Multiplex Biomarker Panel for Hypertrophic Cardiomyopathy Using Quantitative Proteomics and Machine Learning.

Mol Cell Proteomics 2020 Jan 13;19(1):114-127. Epub 2020 Aug 13.

Translational Mass Spectrometry Research Group, UCL Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London WC1N 1EH, UK; Institute of Child Health, University College London, London, WC1N 1EH, UK. Electronic address:

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January 2020

Personalized medicine for dilated cardiomyopathy.

Authors:
Perry M Elliott

Eur Heart J 2020 Nov 11. Epub 2020 Nov 11.

University College London, UK.

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November 2020

The end of the beginning for drug therapy in obstructive hypertrophic cardiomyopathy with EXPLORER-HCM.

Authors:
Perry M Elliott

Cardiovasc Res 2020 Nov;116(13):e175-e178

Institute of Cardiovascular Science, University College London, Paul O'Gorman Building, 72 Huntley St., London WC1E 6AG, UK.

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November 2020

The European Heart Journal: leading the fight to reduce the global burden of cardiovascular disease.

Eur Heart J 2020 Sep;41(33):3113-3116

Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK Copenhagen, Denmark.

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September 2020

Penetrance of Hypertrophic Cardiomyopathy in Sarcomere Protein Mutation Carriers.

J Am Coll Cardiol 2020 08;76(5):550-559

Barts Heart Centre, St. Bartholomew's Hospital, London, United Kingdom; University College London Institute of Cardiovascular Science, London, United Kingdom. Electronic address:

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August 2020

DPD Quantification in Cardiac Amyloidosis: A Novel Imaging Biomarker.

JACC Cardiovasc Imaging 2020 06;13(6):1353-1363

Barts Heart Centre, St. Bartholomew's Hospital, London, United Kingdom; Institute of Nuclear Medicine, University College London, London, United Kingdom; NIHR University College London Hospitals Biomedical Research Centre, London, United Kingdom. Electronic address:

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June 2020

Cryptic Splice-Altering Variants in Are a Prevalent Cause of Hypertrophic Cardiomyopathy.

Circ Genom Precis Med 2020 06 12;13(3):e002905. Epub 2020 May 12.

Inherited Cardiovascular Disease Unit, St Bartholomew's Hospital, Barts Health NHS Trust (L.R.L., E.Q., P.M.E.).

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June 2020

Arrhythmogenic Cardiomyopathy: A Disease or Merely a Phenotype?

Eur Cardiol 2020 Feb 26;15:1-5. Epub 2020 Feb 26.

Institute of Cardiovascular Science, University College London, London, UK.

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February 2020

A microRNA Expression Profile as Non-Invasive Biomarker in a Large Arrhythmogenic Cardiomyopathy Cohort.

Int J Mol Sci 2020 Feb 24;21(4). Epub 2020 Feb 24.

Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Cardiovascular Pathology, Cardiology and Biostatistics Units, 35121 Padua, Italy.

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February 2020

Dilated cardiomyopathy: so many cardiomyopathies!

Eur Heart J 2020 Oct;41(39):3784-3786

Cardiovascular Department, Center for Diagnosis and Treatment of Cardiomyopathies, Azienda Sanitaria Universitaria Integrata (ASUITS), University of Trieste, Via P. Valdoni 7, 34100 Trieste, Italy.

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October 2020

Prevalence of variants detected by whole-exome sequencing in hypertrophic cardiomyopathy.

Amyloid 2019 Dec 25;26(4):243-247. Epub 2019 Sep 25.

St. Bartholomew's Centre for Inherited Cardiovascular Disease, St Bartholomew's Hospital , London , UK.

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December 2019

Screening for Transthyretin Amyloid Cardiomyopathy in Everyday Practice.

JACC Heart Fail 2019 08 10;7(8):709-716. Epub 2019 Jul 10.

Heart Failure and Inherited Cardiac Diseases Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, CIBERCV, Madrid, Spain; University Francisco de Vitoria (UFV), Pozuelo de Alarcon, Madrid, Spain. Electronic address:

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August 2019

Identification of a Multiplex Biomarker Panel for Hypertrophic Cardiomyopathy Using Quantitative Proteomics and Machine Learning.

Mol Cell Proteomics 2020 01 26;19(1):114-127. Epub 2019 Jun 26.

Translational Mass Spectrometry Research Group, UCL Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London WC1N 1EH, UK

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January 2020

Why systematic literature reviews in Fabry disease should include all published evidence.

Eur J Med Genet 2019 Oct 10;62(10):103702. Epub 2019 Jun 10.

INSERM U1018, University of Paris-Sud, University of Paris-Descartes, Paris, France.

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October 2019

Hypertrophic Cardiomyopathy-Need for Gene-Specific Treatment?-Reply.

JAMA Cardiol 2019 08;4(8):831-832

UCL Institute of Cardiovascular Science, UCL Faculty of Population Health Sciences, University College London, London, United Kingdom.

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August 2019

Left ventricular non-compaction: have we reached the limits of conventional imaging?

Eur Heart J 2020 Apr;41(14):1437-1438

Institute of Cardiovascular Science, University College London, London, UK.

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April 2020

Yield of Clinical Screening for Hypertrophic Cardiomyopathy in Child First-Degree Relatives.

Circulation 2019 07 22;140(3):184-192. Epub 2019 Apr 22.

Centre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital, London UK (G.N., J.J., E.F., H.F., E.L., E.C., J.P.K.).

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July 2019

Arrhythmogenic cardiomyopathies (ACs): diagnosis, risk stratification and management.

Heart 2019 07 21;105(14):1117-1128. Epub 2019 Feb 21.

UCL Institute of Cardiovascular Science, University College London, London, UK.

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July 2019

Tafamidis for the treatment of transthyretin amyloidosis.

Future Cardiol 2019 03 15;15(2):53-61. Epub 2019 Feb 15.

University College London Institute for Cardiovascular Science & Barts Heart Centre, St Bartholomew's Hospital, London, UK.

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March 2019

Proteomic Analysis of the Myocardium in Hypertrophic Obstructive Cardiomyopathy.

Circ Genom Precis Med 2018 12;11(12):e001974

University College London Institute of Cardiovascular Science, London, United Kingdom (C.J.C., P.S., T.A.T., J.C.M., L.R.L., C.G.A.M., W.J.M., P.M.E.).

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December 2018

Cardiac manifestations of McArdle disease.

Eur Heart J 2019 01;40(4):397-398

Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, UK.

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January 2019

Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy.

N Engl J Med 2018 Sep 27;379(11):1007-1016. Epub 2018 Aug 27.

From the Columbia University Vagelos College of Physicians and Surgeons (M.S.M.) and Pfizer (J.H.S., A.I.B., P.H., J.S., M.B.S.), New York; Syneos Health, Raleigh, NC (B.G.); University College London and St. Bartholomew's Hospital, London (P.M.E.); the Amyloidosis Center, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, and the University of Pavia, Pavia (G.M.), and the Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna (C.R.) - both in Italy; the Amyloidosis Center (CEPARM), Federal University of Rio de Janeiro, Rio de Janeiro (M.W-C.); the Amyloidosis Center, Medical University of Heidelberg, Heidelberg, Germany (A.V.K.); the Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (M.G.); Stanford University School of Medicine, Stanford, CA (R.W.); the French Referral Center for Cardiac Amyloidosis, Amyloidosis Mondor Network, GRC Amyloid Research Institute and Department of Cardiology, Assistance Publique-Hôpitaux de Paris, CHU Henri Mondor, and INSERM Unité 955, Clinical Investigation Center 006, and DHU ATVB, Creteil, France (T.D.); Penn Presbyterian Medical Center, University of Pennsylvania Health System, Philadelphia (B.M.D.); the Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago (S.J.S.); Cleveland Clinic, Cleveland (M.H.); the Medical University of South Carolina, Charleston (D.P.J.); and Pfizer, Groton, CT (T.A.P., S.R., M.S.).

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September 2018

Arrhythmogenic right ventricular cardiomyopathy as a hidden cause of paediatric myocarditis presentation.

Int J Cardiol 2018 11 2;271:113-114. Epub 2018 Jul 2.

Institute for Cardiovascular Science, University College London, London, UK; Barts Heart Centre, St Bartholomew's Hospital, London, UK.

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November 2018

The effect of enzyme replacement therapy on clinical outcomes in paediatric patients with Fabry disease - A systematic literature review by a European panel of experts.

Mol Genet Metab 2019 03 26;126(3):212-223. Epub 2018 Apr 26.

French Referral Center for Fabry disease, Division of Medical Genetics and INSERM U1179, University of Versailles, Paris-Saclay University, Montigny, France.

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March 2019

On the Road from Gene to Therapy in Inherited Cardiomyopathies.

Heart Fail Clin 2018 Apr;14(2):xi-xv

Department of Internal Medicine, Division of Cardiovascular Medicine, Department of Molecular and Integrative Physiology, Program for Inherited Cardiomyopathies, Cardiovascular Center Floor 3, 1500 East Medical Center Drive, SPC 5856, Ann Arbor, MI 48109, USA. Electronic address:

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April 2018

Epidemiology and Clinical Aspects of Genetic Cardiomyopathies.

Heart Fail Clin 2018 Apr;14(2):119-128

Cardiomyopathies and Heart Failure Unit, Monaldi Hospital, Via Leonardo Bianchi, Naples 84100, Italy; Department of Cardiology, UCL Institute of Cardiovascular Science, Gower Street, London WC1E 6BT, UK; Department of Cardiothoracic Sciences, Università della Campania "Luigi Vanvitelli", Via Leonardo Bianchi, Naples 84100, Italy.

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April 2018

Transforming care for rare and inherited cardiovascular diseases through education and training.

Int J Cardiol 2018 04;257:342-343

Vita-Salute University, Milan, Italy; San Raffaele Hospital, Milan, Italy.

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April 2018

Multifocal ectopic Purkinje-related premature contractions: Sorting the wheat from the chaff.

Authors:
Perry M Elliott

Int J Cardiol 2018 04;257:218-219

Institute of Cardiovascular Science, University College London, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom. Electronic address:

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April 2018

Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology.

Circ Genom Precis Med 2018 02;11(2):e001813

From the Institute of Cardiovascular Science (R.C.L., V.K.K., R.E.F., N.H.C., R.P.H., P.J.T., P.D.L., P.M.E., L.C.) and Metabolism and Experimental Therapeutics, Division of Medicine (R.B.), University College London, United Kingdom; European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Hinxton, United Kingdom (P.R., D.O.-S.); Gene Ontology Consortium (P.R., T.Z.B., D.O.-S., J.A.B., D.P.H.); The Zebrafish Model Organism Database, University of Oregon, Eugene (D.G.H.); Rat Genome Database, Human Molecular Genetics Center, Medical College of Wisconsin, Milwaukee (S.J.F.L.); Arabidopsis Information Resource, Phoenix Bioinformatics, Fremont, CA (T.Z.B.); FlyBase, University of Cambridge, United Kingdom (S.T.); Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME (J.A.B., D.P.H.); Oxbridge BHF Centre of Regenerative Medicine, Department of Physiology, Anatomy and Genetics, University of Oxford, United Kingdom (P.R.R.); and William Harvey Heart Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (A.T.).

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February 2018

Evolving Story of Clinical Trials in Hypertrophic Cardiomyopathy.

Authors:
Perry M Elliott

Circ Heart Fail 2018 01;11(1):e004572

From the St Bartholomew's Hospital and the Institute of Cardiovascular Science, University College London, United Kingdom.

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January 2018

Evolving concepts in dilated cardiomyopathy.

Eur J Heart Fail 2018 02 22;20(2):228-239. Epub 2017 Dec 22.

Cardiovascular Department 'Ospedali Riuniti' and University of Trieste, Trieste, Italy.

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February 2018

Lamin and the heart.

Heart 2018 03 25;104(6):468-479. Epub 2017 Nov 25.

Biomedical Research Center, NIHR University College London Hospitals, London, UK.

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March 2018

Isolated aortic root dilation in homocystinuria.

J Inherit Metab Dis 2018 01 4;41(1):109-115. Epub 2017 Oct 4.

Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

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January 2018

Fabry Disease: A Rare Condition Emerging From the Darkness.

Authors:
Perry M Elliott

Circ Cardiovasc Genet 2017 08;10(4)

From the Institute of Cardiovascular Science, University College London, United Kingdom.

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August 2017

Rare Disease in Cardiovascular Medicine I.

Eur Heart J 2017 06;38(21):1625-1628

UCL Institute for Cardiovascular Science, University College London, Barts Heart Centre St Bartholomew's Hospital, London, UK.

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June 2017

Disease Severity and Exercise Testing Reduce Subcutaneous Implantable Cardioverter-Defibrillator Left Sternal ECG Screening Success in Hypertrophic Cardiomyopathy.

Circ Arrhythm Electrophysiol 2017 Apr;10(4)

From the Department of Cardiac Electrophysiology, The Barts Heart Center, St Bartholomew's Hospital, London, United Kingdom (N.T.S., M.B., R.P., P.M.E., P.D.L.); Institute of Cardiovascular Science, University College London, United Kingdom (N.T.S., K.H.P., K.Q., A.T., P.M.E., P.D.L.); and Department of Cardiology, St George's Hospital London, United Kingdom (M.T.-E.).

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April 2017

Community delivery of semiautomated fractal analysis tool in cardiac mr for trabecular phenotyping.

J Magn Reson Imaging 2017 10 2;46(4):1082-1088. Epub 2017 Feb 2.

Barts Heart Center, Cardiovascular Magnetic Resonance Imaging Unit, St Bartholomew's Hospital, West Smithfield, London, UK.

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October 2017

Inverted U-Shaped Relation Between the Risk of Sudden Cardiac Death and Maximal Left Ventricular Wall Thickness in Hypertrophic Cardiomyopathy.

Circ Arrhythm Electrophysiol 2016 06;9(6)

From the Inherited Cardiac Diseases Unit, Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom (C.O'M., W.J.M., P.M.E.); Biostatistics Group, University College London Hospitals/University College London Research Support Centre, London, United Kingdom (F.J., R.Z.O.); Department of Statistical Science, University College London, London, United Kingdom (R.Z.O.); Research Unit, Department of Cardiology, A Coruña University Hospital, and Galician Health Service, A Coruña, Spain (L.M., M.O.-G.); Unit of Inherited Cardiovascular Diseases, 1st Department of Cardiology, University of Athens, Athens, Greece (A.A.); Institute of Cardiology, Department of Specialised, Experimental and Diagnostic Medicine, University of Bologna, Bologna, Italy (C.R., E.B.); Cardiac Department, University Hospital Virgen Arrixaca, Murcia, Spain (J.R.G.); and Monaldi Hospital, Second University of Naples, Naples, Italy (G.L.).

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June 2016

Hypertrophic Cardiomyopathy: Job Done or Work in Progress?

Authors:
Perry M Elliott

J Am Coll Cardiol 2016 Mar;67(12):1410-1411

University College London and St. Bartholomew's Hospital, London, United Kingdom. Electronic address:

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March 2016

A Family History of Sudden Death Should Not Be a Primary Indication for an Implantable Cardioverter Defibrillator in Hypertrophic Cardiomyopathy.

Can J Cardiol 2015 Nov 12;31(11):1407-9. Epub 2015 Aug 12.

Inherited Cardiovascular Disease, St Bartholomew's Hospital, West Smithfield, London, United Kingdom. Electronic address:

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November 2015

Cardiopulmonary Exercise Testing and Prognosis in Hypertrophic Cardiomyopathy.

Circ Heart Fail 2015 Nov 15;8(6):1022-31. Epub 2015 Sep 15.

From the Institute of Cardiovascular Science (C.J.C., B.M., W.J.M., P.M.E.), and Institute of Neurology (K.R.), University College London, London, United Kingdom; Royal Free Hospital NHS Trust, London, United Kingdom (A.B.); and University College London Hospitals NHS Trust, London, United Kingdom (A.P.).

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November 2015

Fractal frontiers in cardiovascular magnetic resonance: towards clinical implementation.

J Cardiovasc Magn Reson 2015 Sep 7;17:80. Epub 2015 Sep 7.

UCL Institute of Cardiovascular Science, University College London, Gower Street, London, WC1E 6BT, UK.

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September 2015

Abnormal septal convexity into the left ventricle occurs in subclinical hypertrophic cardiomyopathy.

J Cardiovasc Magn Reson 2015 Jul 30;17:64. Epub 2015 Jul 30.

Division of Cardiovascular Imaging and Inherited Cardiac Disease Unit, The Heart Hospital, Institute of Cardiovascular Science, University College London, London, UK.

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July 2015

Current applications of biomarkers in cardiomyopathies.

Expert Rev Cardiovasc Ther 2015 ;13(7):825-37

Institute of Cardiovascular Science, The Heart Hospital, 16-18 Westmoreland Street, London W1G 8PH, UK.

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February 2016

Fractal Analysis of Myocardial Trabeculations in 2547 Study Participants: Multi-Ethnic Study of Atherosclerosis.

Radiology 2015 Dec 10;277(3):707-15. Epub 2015 Jun 10.

From the Division of Cardiovascular Imaging and Biostatistics, The Heart Hospital, 16-18 Westmoreland Street, London, England, W1G 8PH (G.C., P.B., W.J.M., P.M.E., J.C.M.); UCL Institute of Cardiovascular Science, University College London, London, England (G.C., V.M., W.J.M., P.M.E., J.C.M.); Cardiovascular Biomedical Research Unit, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, England (F.Z., S.E.P.); Division of Cardiovascular Imaging, The London Chest Hospital, London, England (F.Z., S.E.P.); UCL Center for Cardiovascular Imaging and Great Ormond Street Hospital for Children, London, England (V.M.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (C.L.); Department of Radiology, Hospital Graubuenden, Loestrasse, Switzerland (N.K.B.); Department of Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Md (J.A.C.L., D.A.B.); and Department of Cardiovascular Imaging, Johns Hopkins Hospital, Baltimore, Md (D.A.B.).

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December 2015

Almanac 2014: cardiomyopathies.

Turk Kardiyol Dern Ars 2015 Apr;43(3):302-14

Inherited Cardiac Diseases Unit, The Heart Hospital, University College London, London, UK.

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April 2015

Improving the diagnostic accuracy for detecting cardiac sarcoidosis.

Expert Rev Cardiovasc Ther 2015 Feb;13(2):223-36

The Heart Hospital, 16-18 Westmoreland Street, London, W1G 8PH, UK.

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February 2015

A straightforward guide to the sarcomeric basis of cardiomyopathies.

Heart 2014 Dec 30;100(24):1916-23. Epub 2014 Sep 30.

Institute of Cardiovascular Science, University College London, London, UK.

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December 2014

Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy.

Circ Cardiovasc Imaging 2014 Nov 16;7(6):863-71. Epub 2014 Sep 16.

From the Department of Cardiovascular Science (G.C., L.R.L., V.P., V.M., W.J.M., P.M.E., J.C.M.) and Biostatistics Joint Research Office (P.B.), University College London, London, United Kingdom; Department of Inherited Cardiovascular Diseases (G.C., L.R.L., V.P., M.T.E., W.J.M., P.M.E., J.C.M.) and Cardiac Imaging Department (G.C., G.F., M.T.E., W.J.M., J.C.M.), Barts Heart Centre, London, United Kingdom; Department of Developmental Biology, MRC National Institutes for Medical Research, Mill Hill, United Kingdom (T.J.M.); Department of Radiology, University of Pennsylvania, Philadelphia (C.L.); Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford Center for Clinical Magnetic Resonance Research (OCMR), Oxford, United Kingdom (V.M.F.); UCL Department for Cardiovascular Imaging, Great Ormond Street Hospital for Children, London, United Kingdom (V.M.); Department of Cardiology, Mount Sinai Roosevelt Hospital, Icahn School of Medicine at Mount Sinai, New York, NY (M.V.S.); Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor (S.M.D.); Pediatric Cardiology Department, Washington University School of Medicine, St Louis, MO (C.E.C.); Department of Genetics, Harvard Medical School, Boston, MA (C.E.S.); Radiology and Imaging Sciences Department, National Institutes of Health/Clinical Center, Bethesda, MD (D.A.B.); and Cardiovascular Department, Brigham and Women's Hospital, Boston, MA (C.Y.H.).

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November 2014