Per Soelberg Sorensen

Per Soelberg Sorensen

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Per Soelberg Sorensen

Publications by authors named "Per Soelberg Sorensen"

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Prognostic value of cerebrospinal fluid neurofilament light chain and chitinase-3-like-1 in newly diagnosed patients with multiple sclerosis.

Mult Scler 2019 Oct 16;25(11):1444-1451. Epub 2018 Aug 16.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458518794308DOI Listing
October 2019

Smoking is associated with increased disease activity during natalizumab treatment in multiple sclerosis.

Mult Scler 2019 Aug 2;25(9):1298-1305. Epub 2018 Aug 2.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458518791753DOI Listing
August 2019

Worsening of disability caused by relapses in multiple sclerosis: A different approach.

Mult Scler Relat Disord 2019 Jul 15;32:1-8. Epub 2019 Apr 15.

The Danish Multiple Sclerosis Registry, Department of Neurology, Rigshospitalet, Copenhagen, Denmark; Department of Neurology, Danish Multiple Sclerosis Center Rigshospitalet, University of Copenhagen, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S22110348193017
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http://dx.doi.org/10.1016/j.msard.2019.04.017DOI Listing
July 2019

The changing course of multiple sclerosis: rising incidence, change in geographic distribution, disease course, and prognosis.

Curr Opin Neurol 2019 Jun;32(3):320-326

Department of Neurology, Danish Multiple Sclerosis Center and the Danish Multiple Sclerosis Registry, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1097/WCO.0000000000000695DOI Listing
June 2019

Predictors of treatment outcome in patients with paediatric onset multiple sclerosis.

Mult Scler 2019 May 13:1352458519846100. Epub 2019 May 13.

The Danish Multiple Sclerosis Registry, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark/Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458519846100DOI Listing
May 2019

The Multiple Sclerosis Care Unit.

Mult Scler 2019 Apr 23;25(5):627-636. Epub 2018 Oct 23.

Department of Neurology and Institute of Experimental Neurology, Vita-Salute San Raffaele University, San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518807082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439947PMC
April 2019

Comparative effectiveness of teriflunomide and dimethyl fumarate: A nationwide cohort study.

Neurology 2019 Apr 15;92(16):e1811-e1820. Epub 2019 Mar 15.

From the Danish Multiple Sclerosis Center (M.D.B., T.A.C., F.S., P.S.S., M.M.), Rigshospitalet; Copenhagen University Hospital Rigshospitalet (J.F., H.H.-K.-R.), Glostrup; Slagelse Hospital (M.K.G.); Odense University Hospital (Z.I., T.S.), University of Southern Denmark; Hospital of Southern Jutland (M.K.), Sønderborg; Aalborg University Hospital (Z.M.); Aarhus University Hospital (T.P., P.V.R.); Greater Copenhagen Hospitals-NOH (H.R.), Hillerød; University Hospital of Sjaelland (A.T.), Roskilde; and Department of Neurology, Copenhagen University Hospital Herlev (A.W.), Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000007314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550503PMC
April 2019

Pulsed immune reconstitution therapy in multiple sclerosis.

Ther Adv Neurol Disord 2019 28;12:1756286419836913. Epub 2019 Mar 28.

Department of Neurology, Danish Multiple Sclerosis Center, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1756286419836913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440030PMC
March 2019

Treatment escalation leads to fewer relapses compared with switching to another moderately effective therapy.

J Neurol 2019 Feb 4;266(2):306-315. Epub 2018 Dec 4.

Department of Neurology, Danish Multiple Sclerosis Center, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.

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http://link.springer.com/10.1007/s00415-018-9126-y
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http://dx.doi.org/10.1007/s00415-018-9126-yDOI Listing
February 2019

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis.

Mult Scler 2018 02 20;24(2):96-120. Epub 2018 Jan 20.

Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunology (FZI), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1177/1352458517751049DOI Listing
February 2018

Progressive multiple sclerosis, cognitive function, and quality of life.

Brain Behav 2018 02 5;8(2):e00875. Epub 2018 Jan 5.

Department of Neurology Danish Multiple Sclerosis Center Rigshospitalet University of Copenhagen Copenhagen Denmark.

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http://dx.doi.org/10.1002/brb3.875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822575PMC
February 2018

Defining active progressive multiple sclerosis.

Mult Scler 2017 Nov 23;23(13):1727-1735. Epub 2017 Aug 23.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458517726592DOI Listing
November 2017

Comorbidity in multiple sclerosis is associated with diagnostic delays and increased mortality.

Neurology 2017 Oct 20;89(16):1668-1675. Epub 2017 Sep 20.

From the Danish Multiple Sclerosis Center (A.T., P.S.S., M.M.), Department of Neurology, University of Copenhagen, Rigshospitalet; The Danish Multiple Sclerosis Registry (A.T., N.K.-H., M.M.), Department of Neurology, Rigshospitalet, Copenhagen; Department of Clinical Epidemiology (N.K.-H.), Clinical Institute, University of Aarhus; and The Danish National Institute of Public Health (B.L.), University of Southern Denmark, Copenhagen.

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http://dx.doi.org/10.1212/WNL.0000000000004508DOI Listing
October 2017

Employment, disability pension and income for children with parental multiple sclerosis.

Mult Scler 2017 Jul 28;23(8):1148-1156. Epub 2016 Sep 28.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, Copenhagen, Denmark/The Danish Multiple Sclerosis Registry, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458516672016DOI Listing
July 2017

Monoclonal Antibodies for Relapsing Multiple Sclerosis: A Review of Recently Marketed and Late-Stage Agents.

CNS Drugs 2017 May;31(5):357-371

Danish Multiple Sclerosis Center, Department of Neurology 2082, Rigshospitalet and University of Copenhagen, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s40263-017-0414-3DOI Listing
May 2017

High-dose erythropoietin in patients with progressive multiple sclerosis: A randomized, placebo-controlled, phase 2 trial.

Mult Scler 2017 Apr 5;23(5):675-685. Epub 2016 Aug 5.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458516661048DOI Listing
April 2017

Evolving concepts in the treatment of relapsing multiple sclerosis.

Lancet 2017 04 24;389(10076):1347-1356. Epub 2016 Nov 24.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://dx.doi.org/10.1016/S0140-6736(16)32388-1DOI Listing
April 2017

A comparison of multiple sclerosis clinical disease activity between patients treated with natalizumab and fingolimod.

Mult Scler 2017 Feb 11;23(2):234-241. Epub 2016 Jul 11.

The Danish Multiple Sclerosis Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458516643393DOI Listing
February 2017

Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop.

Mult Scler 2017 01 6:1352458516686847. Epub 2017 Jan 6.

Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1177/1352458516686847DOI Listing
January 2017

Vascular comorbidities in multiple sclerosis: a nationwide study from Denmark.

J Neurol 2016 Dec 3;263(12):2484-2493. Epub 2016 Oct 3.

Department of Neurology, Danish Multiple Sclerosis Center, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00415-016-8295-9DOI Listing
December 2016

Vitamin D supplementation reduces relapse rate in relapsing-remitting multiple sclerosis patients treated with natalizumab.

Mult Scler Relat Disord 2016 Nov 26;10:169-173. Epub 2016 Oct 26.

Rigshospitalet, Copenhagen University Hospital, Danish Multiple Sclerosis Center, Department of Neurology, Blegdamsvej 9, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.msard.2016.10.005DOI Listing
November 2016

Inverse comorbidity in multiple sclerosis: Findings in a complete nationwide cohort.

Mult Scler Relat Disord 2016 Nov 29;10:181-186. Epub 2016 Oct 29.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK-2100 Copenhagen, Denmark; The Danish Multiple Sclerosis Registry, Department of Neurology, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.msard.2016.10.008DOI Listing
November 2016

Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.

Mult Scler 2016 10 19;22(11):1386-1396. Epub 2016 May 19.

Multiple Sclerosis Centre of Catalonia (Cemcat), Department of Neurology-Neuroimmunology, Vall d'Hebron University Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1177/1352458516643600DOI Listing
October 2016

The Danish Multiple Sclerosis Treatment Register.

Clin Epidemiol 2016 25;8:549-552. Epub 2016 Oct 25.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.2147/CLEP.S99500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094645PMC
October 2016

Haematopoietic stem cell transplants should be a second-line therapy for highly active MS - NO.

Mult Scler 2016 09 21;22(10):1260-3. Epub 2016 Jul 21.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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http://dx.doi.org/10.1177/1352458516644341DOI Listing
September 2016

Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis.

J Neurol Neurosurg Psychiatry 2016 08 14;87(8):912-4. Epub 2015 Dec 14.

Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Hvidovre, Denmark Cognitive Systems, Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark.

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http://dx.doi.org/10.1136/jnnp-2015-311375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975821PMC
August 2016

Neurofilament in CSF-A biomarker of disease activity and long-term prognosis in multiple sclerosis.

Mult Scler 2016 08 30;22(9):1112-3. Epub 2016 Jun 30.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458516658560DOI Listing
August 2016

Ozanimod: a better or just another S1P receptor modulator?

Lancet Neurol 2016 Apr 12;15(4):345-7. Epub 2016 Feb 12.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen DK-2100, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)00041-7DOI Listing
April 2016

Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients.

Neurol Neuroimmunol Neuroinflamm 2016 Apr 27;3(2):e202. Epub 2016 Jan 27.

Department of Neurology (H.H., A.M., M.H., D.R., F.D.), Medical University of Innsbruck, Austria; Department of Arthritis and Clinical Immunology (I.A., C.J.L., R.C.A.), Oklahoma Medical Research Foundation, Oklahoma City; Centro di Riferimento Regionale Sclerosi Multipla (A.B., S.N.), Neurologia 2, Azienda Ospedaliero Universitaria San Luigi Gonzaga, Orbassano, Turin, Italy; Centre d'Esclerosi Múltiple de Catalunya (Cemcat) (M.C., X.M.), Unitat de Neuroimmunologia Clínica, Hospital Universitari Vall d'Hebron, Barcelona, Spain; Queen Mary University London (G.G.), Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK; Clinical Department of Neurology (M.G.), Allgemeines Krankenhaus Linz, Austria; Department of Neurology (M.K., F.F.), Medical University of Graz, Austria; Department of Neurology (J.K.), Vrije Universiteit Medical Center, Amsterdam, the Netherlands; Department of Biomedicines and Neurology (R.L.P.L., M.M.), Clinical Neuroimmunology, University of Basel, University Hospital Basel, Switzerland; Clinical Department of Neurology (F. Schautzer), Landeskrankenhaus Villach, Austria; Danish Multiple Sclerosis Center (F. Sellebjerg, P.S.S.), Department of Neurology, Rigshospitalet, University of Copenhagen, Denmark; and Department of Neurology and Neurological Sciences (L.S.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1212/NXI.0000000000000202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747480PMC
April 2016

Association between age at onset of multiple sclerosis and vitamin D level-related factors.

Neurology 2016 Jan 7;86(1):88-93. Epub 2015 Oct 7.

From Rigshospitalet, Copenhagen University Hospital, Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000002075DOI Listing
January 2016

Multiple sclerosis. Generic glatiramer acetate--a step toward cheaper MS drugs?

Nat Rev Neurol 2016 Jan 4;12(1):5-6. Epub 2015 Dec 4.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nrneurol.2015.224DOI Listing
January 2016

The potential role for ocrelizumab in the treatment of multiple sclerosis: current evidence and future prospects.

Ther Adv Neurol Disord 2016 Jan;9(1):44-52

Danish Multiple Sclerosis Center, Department of Neurology, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1756285615601933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710102PMC
January 2016

Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.

Mult Scler 2015 Oct 22;21(11):1414-22. Epub 2014 Dec 22.

Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Danish Multiple Sclerosis Center, Denmark.

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http://journals.sagepub.com/doi/10.1177/1352458514563590
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http://dx.doi.org/10.1177/1352458514563590DOI Listing
October 2015

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.

Authors:
Jenny C Taylor Hilary C Martin Stefano Lise John Broxholme Jean-Baptiste Cazier Andy Rimmer Alexander Kanapin Gerton Lunter Simon Fiddy Chris Allan A Radu Aricescu Moustafa Attar Christian Babbs Jennifer Becq David Beeson Celeste Bento Patricia Bignell Edward Blair Veronica J Buckle Katherine Bull Ondrej Cais Holger Cario Helen Chapel Richard R Copley Richard Cornall Jude Craft Karin Dahan Emma E Davenport Calliope Dendrou Olivier Devuyst Aimée L Fenwick Jonathan Flint Lars Fugger Rodney D Gilbert Anne Goriely Angie Green Ingo H Greger Russell Grocock Anja V Gruszczyk Robert Hastings Edouard Hatton Doug Higgs Adrian Hill Chris Holmes Malcolm Howard Linda Hughes Peter Humburg David Johnson Fredrik Karpe Zoya Kingsbury Usha Kini Julian C Knight Jonathan Krohn Sarah Lamble Craig Langman Lorne Lonie Joshua Luck Davis McCarthy Simon J McGowan Mary Frances McMullin Kerry A Miller Lisa Murray Andrea H Németh M Andrew Nesbit David Nutt Elizabeth Ormondroyd Annette Bang Oturai Alistair Pagnamenta Smita Y Patel Melanie Percy Nayia Petousi Paolo Piazza Sian E Piret Guadalupe Polanco-Echeverry Niko Popitsch Fiona Powrie Chris Pugh Lynn Quek Peter A Robbins Kathryn Robson Alexandra Russo Natasha Sahgal Pauline A van Schouwenburg Anna Schuh Earl Silverman Alison Simmons Per Soelberg Sørensen Elizabeth Sweeney John Taylor Rajesh V Thakker Ian Tomlinson Amy Trebes Stephen Rf Twigg Holm H Uhlig Paresh Vyas Tim Vyse Steven A Wall Hugh Watkins Michael P Whyte Lorna Witty Ben Wright Chris Yau David Buck Sean Humphray Peter J Ratcliffe John I Bell Andrew Om Wilkie David Bentley Peter Donnelly Gilean McVean

Nat Genet 2015 Jul 18;47(7):717-726. Epub 2015 May 18.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601524PMC
July 2015

Multiple sclerosis impairs regional functional connectivity in the cerebellum.

Neuroimage Clin 2014 27;4:130-8. Epub 2013 Nov 27.

Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Kettegaard Allé 30, 2650 Hvidovre, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S22131582130015
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http://dx.doi.org/10.1016/j.nicl.2013.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871286PMC
May 2015

A systematic review of the incidence and prevalence of sleep disorders and seizure disorders in multiple sclerosis.

Mult Scler 2015 Mar 22;21(3):342-9. Epub 2014 Dec 22.

Department of Neurology and Neurotherapeutics, University of Texas Southwestern, Dallas, TX, USA.

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http://dx.doi.org/10.1177/1352458514564486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429167PMC
March 2015

Physical and social environment and the risk of multiple sclerosis.

Mult Scler Relat Disord 2014 Sep 21;3(5):600-6. Epub 2014 Jul 21.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.msard.2014.07.002DOI Listing
September 2014

Gender and autoimmune comorbidity in multiple sclerosis.

Mult Scler 2014 08 5;20(9):1244-51. Epub 2014 Feb 5.

Danish Multiple Sclerosis Center, Department of Neurology, Neuroscience Centre, Rigshospitalet, Copenhagen, Denmark University of Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458514521515DOI Listing
August 2014

Defining the clinical course of multiple sclerosis: the 2013 revisions.

Neurology 2014 Jul 28;83(3):278-86. Epub 2014 May 28.

From the Corinne Goldsmith Dickenson Center for Multiple Sclerosis (F.D.L., A.E.M.), Icahn School of Medicine at Mount Sinai, New York, NY; Scientific and Clinical Review Associates, LLC (S.C.R.), Salisbury, CT; The Mellen Center for MS Treatment and Research (J.A.C., R.J.F., R.A.R.), Cleveland Clinic, OH; the Department of Biostatistics (G.R.C.), University of Alabama at Birmingham; the Danish Multiple Sclerosis Center (P.S.S.), Department of Neurology, Copenhagen University Hospital Rigshospitalet, Denmark; University College London Institute of Neurology (A.J.T.), UK; the Department of Neurology (J.S.W., J.A.L.), University of Texas Health Sciences Center, Houston; the Department of Neurology (L.J.B.), New York University Langone Medical Center, New York; the Division of Neurology (B. Banwell), The Children's Hospital of Philadelphia, PA; the Departments of Radiology and Nuclear Medicine (F.B.) and Neurology (C.H.P.), VU Medical Center, Amsterdam, the Netherlands; Research Programs Department (B. Bebo), National Multiple Sclerosis Society, New York, NY; the Department of Neurology (P.A.C.), The Johns Hopkins Hospital, Baltimore, MD; Fédération de Neurologie (M.C.), CHU Hôpital Purpan, Toulouse, France; the Department of Neurology (G.C.), Scientific Institute San Raffaele, University Vita-Salute San Raffaele, Milan, Italy; University of Ottawa and the Ottawa Hospital Research Institute (M.S.F.), Canada; the Department of Neurology (A.D.G.), University of Rochester Medical Center, NY; the Departments of Neurology, Radiology and Neuroscience (M.I.), Mount Sinai School of Medicine, New York, NY; the Department of Neurology (L.K.), University Hospital, Basel, Switzerland; the Department of Neurology (B.C.K.), Heinrich-Heine-University, Düsseldorf, Germany; the Department of Neurology (C.L.), Salpêtrière Hospital, UPMC, Paris, France; the Department of Neurology-Neuroimmunology (X.M.), Cemcat, Hospital Universitari Vall d'Hebron, Barcelona, Spain; the Division of

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http://dx.doi.org/10.1212/WNL.0000000000000560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117366PMC
July 2014

Effects of fingolimod in relapsing-remitting multiple sclerosis.

Lancet Neurol 2014 Jun 28;13(6):526-7. Epub 2014 Mar 28.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, DK2100 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(14)70067-5DOI Listing
June 2014

Recurrence or rebound of clinical relapses after discontinuation of natalizumab therapy in highly active MS patients.

J Neurol 2014 Jun 12;261(6):1170-7. Epub 2014 Apr 12.

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark,

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http://link.springer.com/content/pdf/10.1007/s00415-014-7325
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http://link.springer.com/10.1007/s00415-014-7325-8
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http://dx.doi.org/10.1007/s00415-014-7325-8DOI Listing
June 2014

New management algorithms in multiple sclerosis.

Curr Opin Neurol 2014 Jun;27(3):246-59

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1097/WCO.0000000000000096DOI Listing
June 2014

[Fampridine and multiple sclerosis].

Ugeskr Laeger 2014 Jan;176(3A):V06130416

Neurologisk Klinik, Dansk Multipel Sklerose Center, Rigshospitalet, Blegdamsvej 9, 2100 København Ø.

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January 2014

Differential microRNA expression in blood in multiple sclerosis.

Mult Scler 2013 Dec 17;19(14):1849-57. Epub 2013 Jun 17.

Department of Neurology, Copenhagen University Hospital Rigshospitalet, Denmark.

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http://dx.doi.org/10.1177/1352458513490542DOI Listing
December 2013

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

Reproduction and the risk of multiple sclerosis.

Mult Scler 2013 Oct 18;19(12):1604-9. Epub 2013 Mar 18.

Department of Neurology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458513481397DOI Listing
October 2013

Clinically silent PML and prolonged immune reconstitution inflammatory syndrome in a patient with multiple sclerosis treated with natalizumab.

Mult Scler 2013 Aug 18;19(9):1226-9. Epub 2013 Mar 18.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Denmark.

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http://dx.doi.org/10.1177/1352458513481010DOI Listing
August 2013

CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis.

Mult Scler 2013 Jun 24;19(7):877-84. Epub 2012 Nov 24.

University of Copenhagen and Department of Neurology, Copenhagen University Hospital Rigshospitalet, Denmark.

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http://journals.sagepub.com/doi/10.1177/1352458512466929
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http://dx.doi.org/10.1177/1352458512466929DOI Listing
June 2013

Effect of natalizumab on circulating CD4+ T-cells in multiple sclerosis.

PLoS One 2012 30;7(11):e47578. Epub 2012 Nov 30.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047578PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511477PMC
May 2013

[Limited effect of interferon-beta for the treatment of secondary progressive multiple sclerosis].

Ugeskr Laeger 2013 May;175(19):1342-4

Dansk Multipel Sclerose Center, Afsnit 2082 N5, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark.

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May 2013

Expanded functional coupling of subcortical nuclei with the motor resting-state network in multiple sclerosis.

Mult Scler 2013 Apr 25;19(5):559-66. Epub 2012 Sep 25.

Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Denmark.

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http://dx.doi.org/10.1177/1352458512460416DOI Listing
April 2013

MRI outcomes with cladribine tablets for multiple sclerosis in the CLARITY study.

J Neurol 2013 Apr 21;260(4):1136-46. Epub 2012 Dec 21.

Department of Neurology and Institute of Experimental Neurology, Scientific Institute H.S. Raffaele, Università Vita-Salute San Raffaele, via Olgettina 60, 20132 Milan, Italy.

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http://dx.doi.org/10.1007/s00415-012-6775-0DOI Listing
April 2013

Preserved in vivo response to interferon-alpha in multiple sclerosis patients with neutralising antibodies against interferon-beta (REPAIR study).

Mult Scler Relat Disord 2013 Apr 11;2(2):141-6. Epub 2012 Dec 11.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.msard.2012.10.001DOI Listing
April 2013

Endogenous and recombinant type I interferons and disease activity in multiple sclerosis.

PLoS One 2012 6;7(6):e35927. Epub 2012 Jun 6.

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035927PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368920PMC
November 2012

[Deaths related to physical restraint of very agitated persons should be possible to avoid].

Ugeskr Laeger 2012 Oct;174(40):2367

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October 2012

[Multiple Sclerosis Treatment Registry].

Ugeskr Laeger 2012 Oct;174(42):2537

Afsnit 7821, Rigshospitalet, Blegdamsvej 9, Copenhagen.

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October 2012

Cellular sources of dysregulated cytokines in relapsing-remitting multiple sclerosis.

J Neuroinflammation 2012 Sep 14;9:215. Epub 2012 Sep 14.

Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, Copenhagen, 2100, Denmark.

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http://dx.doi.org/10.1186/1742-2094-9-215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503813PMC
September 2012

Deaths and disability from natalizumab are no longer tolerable: No - (they can be avoided).

Mult Scler 2012 Aug;18(8):1070-2

Danish Multiple Sclerosis Center, University of Copenhagen and Department of Neurology, Rigshospitalet, Denmark.

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http://dx.doi.org/10.1177/1352458512451946DOI Listing
August 2012

[Diagnosis of multiple sclerosis--the 2010 revision of the McDonald criteria].

Ugeskr Laeger 2012 Mar;174(13):862-5

Dansk Multipel Sclerose Center, Neurologisk Klinik, Rigshospitalet, København Ø, Denmark.

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March 2012

Risk stratification for progressive multifocal leukoencephalopathy in patients treated with natalizumab.

Mult Scler 2012 Feb;18(2):143-52

Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet and Copenhagen University, Denmark.

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http://dx.doi.org/10.1177/1352458511435105DOI Listing
February 2012

Cladribine tablets for relapsing-remitting multiple sclerosis: Efficacy across patient subgroups from the phase III CLARITY study.

Mult Scler Relat Disord 2012 Jan 15;1(1):49-54. Epub 2011 Sep 15.

Merck Serono SA-Geneva, 9 Chemin de Mines,1202 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2011.08.006DOI Listing
January 2012

Why does the north-south gradient of incidence of multiple sclerosis seem to have disappeared on the northern hemisphere?

J Neurol Sci 2011 Dec 7;311(1-2):58-63. Epub 2011 Oct 7.

Department of Neurology, Aarhus University Hospital in Aalborg, Denmark.

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http://dx.doi.org/10.1016/j.jns.2011.09.003DOI Listing
December 2011

Balancing the benefits and risks of disease-modifying therapy in patients with multiple sclerosis.

J Neurol Sci 2011 Dec;311 Suppl 1:S29-34

Danish Multiple Sclerosis Research Centre, Copenhagen University and Rigshospitalet, Copenhagen, Denmark.

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http://linkinghub.elsevier.com/retrieve/pii/S0022510X1170006
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http://dx.doi.org/10.1016/S0022-510X(11)70006-5DOI Listing
December 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Principles of a new treatment algorithm in multiple sclerosis.

Expert Rev Neurother 2011 Mar;11(3):351-62

Department of Neurology, Heinrich-Heine-University Medical School, Düsseldorf, Germany.

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http://dx.doi.org/10.1586/ern.11.15DOI Listing
March 2011

Neutralizing antibodies against interferon-β do not predispose antibodies against natalizumab.

Neurology 2011 Feb;76(8):759-60

Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1212/WNL.0b013e31820d62a4DOI Listing
February 2011

Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis.

Mult Scler 2011 Jan 4;17(1):32-42. Epub 2010 Oct 4.

University of Copenhagen and Danish MS Research Center, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458510382247DOI Listing
January 2011

Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients.

Mult Scler 2010 Aug 1;16(8):942-9. Epub 2010 Jul 1.

Institute for Inflammation Research, Department of Rheumatology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1177/1352458510373264DOI Listing
August 2010