Publications by authors named "Pei-I Ho"

8Publications

Characterization and Use of TurboLuc Luciferase as a Reporter for High-Throughput Assays.

Authors:
Douglas S Auld Janaki Narahari Pei-I Ho Dominick Casalena Vy Nguyen Evelina Cirbaite Doug Hughes John Daly Brian Webb

Biochemistry 2018 08 20;57(31):4700-4706. Epub 2018 Apr 20.

Thermo Fisher Scientific , Rockford , Illinois , United States.

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August 2018

Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays.

Authors:
Ji-Hu Zhang Zhao B Kang Ophelia Ardayfio Pei-i Ho Thomas Smith Iain Wallace Scott Bowes W Adam Hill Douglas S Auld

J Biomol Screen 2014 Jun 18;19(5):651-60. Epub 2013 Nov 18.

Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, Cambridge, MA, USA

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June 2014

Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays.

Authors:
Pei-i Ho Kimberley Yue Pramod Pandey Lyne Breault Fred Harbinski Aaron J McBride Brian Webb Janaki Narahari Natasha Karassina Keith V Wood Adam Hill Douglas S Auld

ACS Chem Biol 2013 May 26;8(5):1009-17. Epub 2013 Mar 26.

Center for Proteomic Chemistry, Novartis Institutes of Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.

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May 2013

Comparison of compound administration methods in biochemical assays: effects on apparent compound potency using either assay-ready compound plates or pin tool-delivered compounds.

Authors:
Thomas Smith Pei-I Ho Kim Yue Zina Itkin Damien MacDougall Mike Paolucci Adam Hill Douglas S Auld

J Biomol Screen 2013 Jan 17;18(1):14-25. Epub 2012 Aug 17.

Lead Finding Platform, Center for Proteomic Chemistry, Novartis Institutes for BioMedical Research, Inc., Cambridge, MA 02139, USA.

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January 2013

Assay development and screening of human DGAT1 inhibitors with an LC/MS-based assay: application of mass spectrometry for large-scale primary screening.

Authors:
Ji-Hu Zhang Thomas P Roddy Pei-I Ho Christopher R Horvath Chad Vickers Steven Stout Brian Hubbard Y Karen Wang W Adam Hill Dejan Bojanic

J Biomol Screen 2010 Jul 18;15(6):695-702. Epub 2010 May 18.

Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.

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July 2010

Mass spectrometric techniques for label-free high-throughput screening in drug discovery.

Authors:
Thomas P Roddy Christopher R Horvath Steven J Stout Kristin L Kenney Pei-I Ho Ji-Hu Zhang Chad Vickers Virendar Kaushik Brian Hubbard Y Karen Wang

Anal Chem 2007 Nov 29;79(21):8207-13. Epub 2007 Sep 29.

Discovery Technologies, Novartis Institute for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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November 2007

Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine.

Authors:
Pei I Ho David Ashline Sirikarnt Dhitavat Daniela Ortiz Scott C Collins Thomas B Shea Eugene Rogers

Neurobiol Dis 2003 Oct;14(1):32-42

Center for Cellular Neurobiology and Neurodegeneration Research, University of Massachusetts-Lowell, Lowell, MA 01854, USA.

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October 2003

Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage.

Authors:
Pei I Ho Daniela Ortiz Eugene Rogers Thomas B Shea

J Neurosci Res 2002 Dec;70(5):694-702

Center for Cellular Neurobiology and Neurodegeneration Research, University of Massachusetts, Lowell, MA 01854, USA.

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December 2002