Pei-Chien Tsai

Pei-Chien Tsai

UNVERIFIED PROFILE

Are you Pei-Chien Tsai?   Register this Author

Register author
Pei-Chien Tsai

Pei-Chien Tsai

Publications by authors named "Pei-Chien Tsai"

Are you Pei-Chien Tsai?   Register this Author

100Publications

2861Reads

17Profile Views

Investigating PUM1 mutations in a Taiwanese cohort with cerebellar ataxia.

Parkinsonism Relat Disord 2019 Sep 7;66:220-223. Epub 2019 Aug 7.

Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University School of Medicine, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.parkreldis.2019.08.004DOI Listing
September 2019

Enhancement of biofuel production by microalgae using cement flue gas as substrate.

Environ Sci Pollut Res Int 2019 Sep 11. Epub 2019 Sep 11.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, No. 100, Shiquan 1st Road, Sanmin District, Kaohsiung City, 807, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11356-019-06425-yDOI Listing
September 2019

Improvement of hyperuricemia in chronic hepatitis C patients receiving directly acting antiviral agents.

J Gastroenterol Hepatol 2019 Aug 14. Epub 2019 Aug 14.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/jgh.14835
Publisher Site
http://dx.doi.org/10.1111/jgh.14835DOI Listing
August 2019

Rapid and Sensitive Analytical Procedure for Biomonitoring of Organophosphates Pesticides' Metabolites in Human Urine Samples using Vortex-Assisted Salt-Induced Liquid-Liquid Microextraction Technique Coupled with UHPLC-MS/MS.

Rapid Commun Mass Spectrom 2019 Aug 30. Epub 2019 Aug 30.

Department of Medicinal and Applied Chemistry, College of Life Sciences, Kaohsiung Medical University, Kaohsiung City, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/rcm.8565DOI Listing
August 2019

CoMutPlotter: a web tool for visual summary of mutations in cancer cohorts.

BMC Med Genomics 2019 Jul 11;12(Suppl 5):99. Epub 2019 Jul 11.

Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12920-019-0510-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624176PMC
July 2019

Risk stratification of non-alcoholic fatty liver disease across body mass index in a community basis.

J Formos Med Assoc 2019 Apr 2. Epub 2019 Apr 2.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jfma.2019.03.014DOI Listing
April 2019

Genetic loci determining total immunoglobulin E levels from birth through adulthood.

Allergy 2019 Mar 28;74(3):621-625. Epub 2018 Nov 28.

Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/all.13654
Publisher Site
http://dx.doi.org/10.1111/all.13654DOI Listing
March 2019

Epigenetic findings in periodontitis in UK twins: a cross-sectional study.

Clin Epigenetics 2019 02 13;11(1):27. Epub 2019 Feb 13.

Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-019-0614-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375219PMC
February 2019

Association of serial serum major histocompatibility complex class I chain-related A measurements with hepatocellular carcinoma in chronic hepatitis C patients after viral eradication.

J Gastroenterol Hepatol 2019 Jan 10;34(1):249-255. Epub 2018 Jul 10.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgh.14359DOI Listing
January 2019

Genetic analysis of ANXA11 variants in a Han Chinese cohort with amyotrophic lateral sclerosis in Taiwan.

Neurobiol Aging 2018 12 10;72:188.e1-188.e2. Epub 2018 Jul 10.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2018.07.002DOI Listing
December 2018

A real world cost effectiveness analysis of interferon-based therapy for HCV naïve super-responders.

J Chin Med Assoc 2018 Aug 1;81(8):670-675. Epub 2018 Jun 1.

Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC; Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC; College of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, Taiwan, ROC; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, ROC. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcma.2017.05.015DOI Listing
August 2018

Investigating CCNF mutations in a Taiwanese cohort with amyotrophic lateral sclerosis.

Neurobiol Aging 2018 02 9;62:243.e1-243.e6. Epub 2017 Oct 9.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2017.09.031DOI Listing
February 2018

Impact of tumor size on the prognosis of hepatocellular carcinoma in patients who underwent liver resection.

J Chin Med Assoc 2018 02 6;81(2):155-163. Epub 2017 Dec 6.

Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC; Department of General Surgery, Changhua Christian Hospital, Changhua, Taiwan, ROC. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcma.2017.06.018DOI Listing
February 2018

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort.

Hum Mol Genet 2018 02;27(4):732-741

Department of Twin Research and Genetic Epidemiology, King's College London, St Thomas' Campus, SE1 7EH London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddx424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886097PMC
February 2018

The IL-6/STAT3 pathway upregulates microRNA-125b expression in hepatitis C virus infection.

Oncotarget 2018 Feb 10;9(13):11291-11302. Epub 2018 Jan 10.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.24129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834265PMC
February 2018

Identification of treatment-experienced hepatitis C patients with poor cost-effectiveness of pegylated interferon plus ribavirin from a real-world cohort.

J Formos Med Assoc 2018 Jan 4;117(1):54-62. Epub 2017 Apr 4.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09296646163047
Publisher Site
http://dx.doi.org/10.1016/j.jfma.2017.02.013DOI Listing
January 2018

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.

Am J Hum Genet 2017 Dec 30;101(6):888-902. Epub 2017 Nov 30.

Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA; Human Genetics Center, School of Public Health, University of Texas Health Science Center, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2017.09.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812919PMC
December 2017

Reply to "cost effectiveness of hepatitis C treatments: Need for a comprehensive evaluation".

Kaohsiung J Med Sci 2017 11 13;33(11):586. Epub 2017 Jul 13.

Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Faculty of Internal Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.kjms.2017.06.003DOI Listing
November 2017

Identification of groups with poor cost-effectiveness of peginterferon plus ribavirin for naïve hepatitis C patients with a real-world cohort and database.

Medicine (Baltimore) 2017 Jun;96(22):e6984

aHepatobiliary Division, Department of Internal Medicine, and Hepatitis Center, Kaohsiung Medical University Hospital bDepartment of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital cFaculty of Internal Medicine, College of Medicine, Kaohsiung Medical University dInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000006984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459714PMC
June 2017

Time-Degenerative Factors and the Risk of Hepatocellular Carcinoma after Antiviral Therapy among Hepatitis C Virus Patients: A Model for Prioritization of Treatment.

Clin Cancer Res 2017 Apr 12;23(7):1690-1697. Epub 2016 Oct 12.

Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-16-0921DOI Listing
April 2017

Corrigendum to "Genetics Variants and Serum Levels of MHC Class I Chain-related A in Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients Post Antiviral Treatment" [EBioMedicine 15 (2017) 81-89].

EBioMedicine 2017 03 1;17:237. Epub 2017 Mar 1.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Faculty of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Institute of Biomedical Sciences, National Sun Yat-Sen University, Taiwan; Liver Center, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2017.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680478PMC
March 2017

Unexpected early tumor recurrence in patients with hepatitis C virus-related hepatocellular carcinoma undergoing interferon-free therapy: Issue of the interval between HCC treatment and antiviral therapy.

J Hepatol 2017 02 10;66(2):464. Epub 2016 Nov 10.

Hepatobiliary Division, Department of Internal Medicine, and Hepatitis Center Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Faculty of Internal Medicine and Hepatitis Research Center, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Liver Center, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2016.10.035DOI Listing
February 2017

Genetics Variants and Serum Levels of MHC Class I Chain-related A in Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients Post Antiviral Treatment.

EBioMedicine 2017 02 1;15:81-89. Epub 2016 Dec 1.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Faculty of Internal Medicine, School of Medicine,College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Institute of Biomedical Sciences, National Sun Yat-Sen University, Taiwan; Liver Center, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2016.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233818PMC
February 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Authors:
Simone Wahl Alexander Drong Benjamin Lehne Marie Loh William R Scott Sonja Kunze Pei-Chien Tsai Janina S Ried Weihua Zhang Youwen Yang Sili Tan Giovanni Fiorito Lude Franke Simonetta Guarrera Silva Kasela Jennifer Kriebel Rebecca C Richmond Marco Adamo Uzma Afzal Mika Ala-Korpela Benedetta Albetti Ole Ammerpohl Jane F Apperley Marian Beekman Pier Alberto Bertazzi S Lucas Black Christine Blancher Marc-Jan Bonder Mario Brosch Maren Carstensen-Kirberg Anton J M de Craen Simon de Lusignan Abbas Dehghan Mohamed Elkalaawy Krista Fischer Oscar H Franco Tom R Gaunt Jochen Hampe Majid Hashemi Aaron Isaacs Andrew Jenkinson Sujeet Jha Norihiro Kato Vittorio Krogh Michael Laffan Christa Meisinger Thomas Meitinger Zuan Yu Mok Valeria Motta Hong Kiat Ng Zacharoula Nikolakopoulou Georgios Nteliopoulos Salvatore Panico Natalia Pervjakova Holger Prokisch Wolfgang Rathmann Michael Roden Federica Rota Michelle Ann Rozario Johanna K Sandling Clemens Schafmayer Katharina Schramm Reiner Siebert P Eline Slagboom Pasi Soininen Lisette Stolk Konstantin Strauch E-Shyong Tai Letizia Tarantini Barbara Thorand Ettje F Tigchelaar Rosario Tumino Andre G Uitterlinden Cornelia van Duijn Joyce B J van Meurs Paolo Vineis Ananda Rajitha Wickremasinghe Cisca Wijmenga Tsun-Po Yang Wei Yuan Alexandra Zhernakova Rachel L Batterham George Davey Smith Panos Deloukas Bastiaan T Heijmans Christian Herder Albert Hofman Cecilia M Lindgren Lili Milani Pim van der Harst Annette Peters Thomas Illig Caroline L Relton Melanie Waldenberger Marjo-Riitta Järvelin Valentina Bollati Richie Soong Tim D Spector James Scott Mark I McCarthy Paul Elliott Jordana T Bell Giuseppe Matullo Christian Gieger Jaspal S Kooner Harald Grallert John C Chambers

Nature 2017 01 21;541(7635):81-86. Epub 2016 Dec 21.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature20784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570525PMC
January 2017

A real-world impact of cost-effectiveness of pegylated interferon/ribavarin regimens on treatment-naïve chronic hepatitis C patients in Taiwan.

Kaohsiung J Med Sci 2017 Jan 18;33(1):44-49. Epub 2016 Nov 18.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.kjms.2016.10.008DOI Listing
January 2017

Clinical and biophysical characterization of 19 mutations.

Ann Clin Transl Neurol 2016 11 1;3(11):854-865. Epub 2016 Sep 1.

Department of Neurology Taipei Veterans General Hospital Taipei 11217 Taiwan; Department of Neurology National Yang-Ming University School of Medicine Taipei 11221 Taiwan; Brain Research Center National Yang-Ming University Taipei 11221 Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/acn3.347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099531PMC
November 2016

Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model.

Sci Rep 2016 11 25;6:37646. Epub 2016 Nov 25.

Department of Twin Research and Genetic Epidemiology, Kings College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep37646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122881PMC
November 2016

Pretreatment glucose status determines HCC development in HCV patients with mild liver disease after curative antiviral therapy.

Medicine (Baltimore) 2016 Jul;95(27):e4157

aHepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan bDepartment of Occupational Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan cFaculty of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan dHealth Management Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan eCenter for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan fInstitute of Biomedical Sciences, National Sun Yat-Sen University.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000004157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058864PMC
July 2016

Spinocerebellar ataxia type 36 in the Han Chinese.

Neurol Genet 2016 Jun 12;2(3):e68. Epub 2016 Apr 12.

Department of Neurology (Y.-C. Lee, C.-T.H., G.-T.L., Y.-C. Liao, B.-W.S.), Taipei Veterans General Hospital, Taiwan; Department of Neurology (Y.-C. Lee, P.-C.T., Y.-C. Liao, B.-W.S.), Institute of Clinical Medicine (Y.-C.G.), and Brain Research Center (Y.-C. Lee, P.-C.T., B.-W.S.), National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Neurology (Y.-C.G.), and School of Medicine (Y.-C.G.), College of Medicine, China Medical University, Taichung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/NXG.0000000000000068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830187PMC
June 2016

Two Novel De Novo GARS Mutations Cause Early-Onset Axonal Charcot-Marie-Tooth Disease.

PLoS One 2015 5;10(8):e0133423. Epub 2015 Aug 5.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University, Taipei, Taiwan.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133423PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526224PMC
May 2016

Mutational analysis of TBK1 in Taiwanese patients with amyotrophic lateral sclerosis.

Neurobiol Aging 2016 Apr 5;40:191.e11-191.e16. Epub 2016 Jan 5.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.022DOI Listing
April 2016

Epigenetic associations of type 2 diabetes and BMI in an Arab population.

Clin Epigenetics 2016 28;8:13. Epub 2016 Jan 28.

Bioinformatics Core, Weill Cornell Medical College in Qatar, Qatar Foundation-Education City, PO Box 24144, Doha, Qatar.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-016-0177-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730771PMC
April 2016

MicroRNA let-7g cooperates with interferon/ribavirin to repress hepatitis C virus replication.

J Mol Med (Berl) 2016 Mar 21;94(3):311-20. Epub 2015 Oct 21.

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Road, Kaohsiung, 807, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-015-1348-1DOI Listing
March 2016

Taiwan cobra cardiotoxin III suppresses EGF/EGFR-mediated epithelial-to-mesenchymal transition and invasion of human breast cancer MDA-MB-231 cells.

Toxicon 2016 Mar 14;111:108-20. Epub 2016 Jan 14.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxicon.2016.01.051DOI Listing
March 2016

Cardiotoxin III Inhibits Hepatocyte Growth Factor-Induced Epithelial-Mesenchymal Transition and Suppresses Invasion of MDA-MB-231 Cells.

J Biochem Mol Toxicol 2016 Jan 17;30(1):12-21. Epub 2015 Aug 17.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbt.21735DOI Listing
January 2016

Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity.

J Hypertens 2016 Jan;34(1):79-87

aDepartment of Twin Research and Genetic Epidemiology, King's College London bNIHR Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust cDepartment of Clinical Pharmacology, King's College London dThe Institute of Cancer Research, London, UK eCardiovascular Engineering, Inc, Norwood, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HJH.0000000000000732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845763PMC
January 2016

Genetic and environmental impacts on DNA methylation levels in twins.

Epigenomics 2016 Jan 18;8(1):105-17. Epub 2015 Dec 18.

Department of Twin Research & Genetic Epidemiology, King's College, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.15.90DOI Listing
January 2016

The tertiary prevention of hepatocellular carcinoma in chronic hepatitis C patients.

J Gastroenterol Hepatol 2015 Dec;30(12):1768-74

Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgh.13012DOI Listing
December 2015

Mortality after exposure to polychlorinated biphenyls and polychlorinated dibenzofurans: a meta-analysis of two highly exposed cohorts.

Int J Cancer 2015 Sep 16;137(6):1427-32. Epub 2015 Mar 16.

Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University (NTU), Taipei, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.29504DOI Listing
September 2015

Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation.

Int J Epidemiol 2015 08 13;44(4):1429-1441. Epub 2015 May 13.

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyv041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588864PMC
August 2015

The association between DNA copy number aberrations at chromosome 5q22 and gastric cancer.

PLoS One 2014 11;9(9):e106624. Epub 2014 Sep 11.

Department of Medical Genetics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Division of Gastrointestinal and General Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106624PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161348PMC
May 2015

Mutational analysis of MATR3 in Taiwanese patients with amyotrophic lateral sclerosis.

Neurobiol Aging 2015 May 14;36(5):2005.e1-4. Epub 2015 Feb 14.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2015.02.008DOI Listing
May 2015

Huge gap between clinical efficacy and community effectiveness in the treatment of chronic hepatitis C: a nationwide survey in Taiwan.

Medicine (Baltimore) 2015 Apr;94(13):e690

From the Hepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital (Ming-Lung Yu, Ming-Lun Yeh, P-CT, J-FH, C-FH, P-CL, Y-HL, M-YH, Z-YL, S-CC, C-YD, W-LC, W-YC); Faculty of Internal Medicine, College of Medicine, and Graduate Institute of Clinical Medicine, and Center for Infectious Disease and Cancer Research, Kaohsiung Medical University (Ming-Lung Yu, J-FH, C-FH, M-HH, Z-YL, S-CC, C-YD, W-LC); Institute of Biomedical Sciences, National Sun Yat-Sen University (Ming-Lung Yu); Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University (C-IH, N-JH); Department of Occupational Medicine, Kaohsiung Municipal Ta-Tung Hospital (C-FH); Department of Preventive Medicine, Kaohsiung Medical University Hospital (M-HH); Department of Occupational Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University (W-YL); and Taiwan Liver Research Foundation, Kaohsiung, Taiwan (W-YC).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000000690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554019PMC
April 2015

coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns.

BMC Bioinformatics 2015 Apr 28;16:131. Epub 2015 Apr 28.

Department of Twin Research and Genetic Epidemiology, St Thomas' Hospital Campus, King's College London, Westminster Bridge Road, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-015-0568-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422463PMC
April 2015

C9ORF72 repeat expansion is not a significant cause of late onset cerebellar ataxia syndrome.

J Neurol Sci 2014 Dec 6;347(1-2):322-4. Epub 2014 Nov 6.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2014.10.042DOI Listing
December 2014

Extensive molecular genetic survey of Taiwanese patients with amyotrophic lateral sclerosis.

Neurobiol Aging 2014 Oct 11;35(10):2423.e1-6. Epub 2014 May 11.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan; Brain Research Center, National Yang-Ming University, Taipei, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2014.05.008DOI Listing
October 2014

Spinocerebellar ataxia 35: novel mutations in TGM6 with clinical and genetic characterization.

Neurology 2014 Oct 24;83(17):1554-61. Epub 2014 Sep 24.

From the Institute of Clinical Medicine (Y.-C.G.), National Yang-Ming University, Taipei; Department of Neurology (Y.-C. Liao, P.-C.T., Y.-C. Lee, B.-W.S.) and Brain Research Center (P.-C.T., Y.-C. Lee, B.-W.S.), National Yang-Ming University School of Medicine, Taipei; Neuroscience Laboratory (Y.-C.G.), Department of Neurology, China Medical University Hospital, Taichung; School of Medicine (Y.-C.G.), College of Medicine, China Medical University, Taichung; Department of Neurology (J.-J.L.), Chushang Show-Chwan Hospital, Nantou; Department of Neurology (J.-J.L.), Chung-Shan Medical University Hospital, Taichung; and Department of Neurology (Y.-C. Liao, P.-C.T., Y.-C. Lee, B.-W.S.), Taipei Veterans General Hospital, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000000909DOI Listing
October 2014

Obesity accelerates epigenetic aging of human liver.

Proc Natl Acad Sci U S A 2014 Oct 13;111(43):15538-43. Epub 2014 Oct 13.

Medical Department 1, University Hospital Dresden, Technical University Dresden, 01307 Dresden, Germany;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1412759111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217403PMC
October 2014

Inhibitory action of naphtho[1,2-b]furan-4,5-dione on hepatocyte growth factor-induced migration and invasion of MDA-MB-231 cells: mechanisms of action.

Clin Exp Pharmacol Physiol 2014 Sep;41(9):716-26

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1440-1681.12272DOI Listing
September 2014

A novel TFG mutation causes Charcot-Marie-Tooth disease type 2 and impairs TFG function.

Neurology 2014 Sep 6;83(10):903-12. Epub 2014 Aug 6.

From the Departments of Neurology (P.-C.T., K.-P.L., Y.-C. Liao, Y.-T.L., B.-W.S., Y.-C. Lee) and Radiology (H.-T.W.), Taipei Veterans General Hospital; Department of Neurology (K.-P.L., Y.-C. Liao, Y.-T.L., B.-W.S., Y.-C. Lee), Brain Research Center (P.-C.T., L.-S.K., M.-J.F., B.-W.S., Y.-C. Lee), Institute of Biomedical Informatics (Y.-H.H.), Center or Systems and Synthetic Biology (Y.-H.H., Y.-S.T.), Department of Life Sciences and Institute of Genome Sciences (L.-S.K., M.-J.F.), Genome Research Center (T.-T.L., L.-S.K.), and Institute of Neuroscience (B.-W.S.), National Yang-Ming University, Taipei; Neuroscience Laboratory (Y.-C.G.), Department of Neurology, China Medical University Hospital, Taichung; School of Medicine (Y.-C.G.), College of Medicine, China Medical University, Taichung; and Institute of Cellular and System Medicine (S.-F.Y.), National Health Research Institutes, Zhunan, Taiwan.

View Article

Download full-text PDF

Source
http://www.neurology.org/content/83/10/903.full.pdf
Web Search
http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000075
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000000758DOI Listing
September 2014

Cardiotoxin III suppresses hepatocyte growth factor-stimulated migration and invasion of MDA-MB-231 cells.

Cell Biochem Funct 2014 Aug 26;32(6):485-95. Epub 2014 Jun 26.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbf.3041DOI Listing
August 2014

Baseline gamma-glutamyl transferase levels strongly correlate with hepatocellular carcinoma development in non-cirrhotic patients with successful hepatitis C virus eradication.

J Hepatol 2014 Jul 5;61(1):67-74. Epub 2014 Mar 5.

Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Faculty of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01688278140013
Publisher Site
http://dx.doi.org/10.1016/j.jhep.2014.02.022DOI Listing
July 2014

Critical residues of class II PHA synthase for expanding the substrate specificity and enhancing the biosynthesis of polyhydroxyalkanoate.

Enzyme Microb Technol 2014 Mar 16;56:60-6. Epub 2014 Jan 16.

Department of Agricultural Chemistry, National Taiwan University, Taipei 10617, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.enzmictec.2014.01.005DOI Listing
March 2014

Naphtho[1,2-b]furan-4,5-dione inhibits MDA-MB-231 cell migration and invasion by suppressing Src-mediated signaling pathways.

Mol Cell Biochem 2014 Feb 26;387(1-2):101-11. Epub 2013 Oct 26.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11010-013-1875-4
Publisher Site
http://dx.doi.org/10.1007/s11010-013-1875-4DOI Listing
February 2014

Improved nondominant hand performance on a laparoscopic virtual reality simulator after playing the Nintendo Wii.

Surg Endosc 2013 Nov 13;27(11):4224-31. Epub 2013 Jun 13.

Department of Surgery, University of Pittsburgh Medical Center, 3945 Forbes Avenue, Suite 325, Pittsburgh, PA, 15213, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00464-013-3027-zDOI Listing
November 2013

Inhibition of Src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells.

Toxicon 2013 Nov 7;74:56-67. Epub 2013 Aug 7.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxicon.2013.07.021DOI Listing
November 2013

Serum microRNA-21 and microRNA-221 as potential biomarkers for cerebrovascular disease.

J Vasc Res 2013 13;50(4):346-54. Epub 2013 Jul 13.

Department of Medical Research, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000351767DOI Listing
October 2013

Circulating microRNAs have a sex-specific association with metabolic syndrome.

J Biomed Sci 2013 Oct 4;20:72. Epub 2013 Oct 4.

Department of Genome Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1423-0127-20-72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851553PMC
October 2013

Mutational analysis of the 5' non-coding region of GJB1 in a Taiwanese cohort with Charcot-Marie-Tooth neuropathy.

J Neurol Sci 2013 Sep 2;332(1-2):51-5. Epub 2013 Jul 2.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2013.06.011DOI Listing
September 2013

Metabolomic markers reveal novel pathways of ageing and early development in human populations.

Int J Epidemiol 2013 Aug 8;42(4):1111-9. Epub 2013 Jul 8.

Department of Twin Research & Genetic Epidemiology, King's College London, London, UK, Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany, Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg, Germany, Pfizer Research Laboratories, Groton, CT, USA, Worldwide R&D, Pfizer Inc., Cambridge, MA, USA, School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia, Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK, Metabolon Inc., 617 Davis Drive, Durham, NC 27713, USA; Department of Physiology and Biophysics, Weill Cornell Medical College in Qatar, Education City, Qatar Foundation, Doha, State of Qatar and Academic Rheumatology, University of Nottingham, Nottingham City Hospital, Nottingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyt094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781000PMC
August 2013

Brazilein suppresses migration and invasion of MDA-MB-231 breast cancer cells.

Chem Biol Interact 2013 Jul 21;204(2):105-15. Epub 2013 May 21.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cbi.2013.05.005DOI Listing
July 2013

A homozygous NOTCH3 mutation p.R544C and a heterozygous TREX1 variant p.C99MfsX3 in a family with hereditary small vessel disease of the brain.

J Chin Med Assoc 2013 Jun 18;76(6):319-24. Epub 2013 Apr 18.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcma.2013.03.002DOI Listing
June 2013

Inhibition of EGF/EGFR activation with naphtho[1,2-b]furan-4,5-dione blocks migration and invasion of MDA-MB-231 cells.

Toxicol In Vitro 2013 Feb 12;27(1):1-10. Epub 2012 Oct 12.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08872333120027
Publisher Site
http://dx.doi.org/10.1016/j.tiv.2012.10.001DOI Listing
February 2013

Mortality after exposure to polychlorinated biphenyls and dibenzofurans: 30 years after the "Yucheng accident".

Environ Res 2013 Jan 29;120:71-5. Epub 2012 Sep 29.

Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.envres.2012.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598583PMC
January 2013

Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway.

Toxicon 2012 Oct 7;60(5):734-43. Epub 2012 Jun 7.

Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxicon.2012.05.019DOI Listing
October 2012

Using epigenome-wide association scans of DNA methylation in age-related complex human traits.

Epigenomics 2012 Oct;4(5):511-26

Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.12.45DOI Listing
October 2012

A hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic ALS in Taiwan.

Neurobiol Aging 2012 Sep 5;33(9):2232.e11-2232.e18. Epub 2012 Jun 5.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2012.05.002DOI Listing
September 2012

MicroRNA-195 regulates vascular smooth muscle cell phenotype and prevents neointimal formation.

Cardiovasc Res 2012 Sep 16;95(4):517-26. Epub 2012 Jul 16.

Department of Genome Medicine, Kaohsiung Medical University, No. 100, TzYou First Road, Kaohsiung 80708, Taiwan.

View Article

Download full-text PDF

Source
https://academic.oup.com/cardiovascres/article-lookup/doi/10
Publisher Site
http://dx.doi.org/10.1093/cvr/cvs223DOI Listing
September 2012

Array-based comparative genomic hybridization-guided identification of reference genes for normalization of real-time quantitative polymerase chain reaction assay data for lymphomas, histiocytic sarcomas, and osteosarcomas of dogs.

Am J Vet Res 2012 Sep;73(9):1335-43

Department of Molecular Biomedical Science, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA.

View Article

Download full-text PDF

Source
http://avmajournals.avma.org/doi/abs/10.2460/ajvr.73.9.1335
Publisher Site
http://dx.doi.org/10.2460/ajvr.73.9.1335DOI Listing
September 2012

MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle.

Carcinogenesis 2012 Aug 10;33(8):1522-30. Epub 2012 May 10.

Department of Medical Genetics College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgs166DOI Listing
August 2012

Sex-specific effect of matrix metalloproteinase-9 functional promoter polymorphism on carotid artery stiffness.

Atherosclerosis 2012 Aug 6;223(2):416-20. Epub 2012 Jun 6.

Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2012.05.031DOI Listing
August 2012