Pedro Rosa-Neto

Pedro Rosa-Neto

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Pedro Rosa-Neto

Pedro Rosa-Neto

Publications by authors named "Pedro Rosa-Neto"

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Targeting Alzheimer's Disease at the Right Time and the Right Place: Validation of a Personalized Approach to Diagnosis and Treatment.

J Alzheimers Dis 2018 ;64(s1):S23-S31

McGill Center for Studies in Aging, Douglas Mental Health Research Institute, Montreal, Canada.

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http://dx.doi.org/10.3233/JAD-179924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004905PMC
June 2019

Constrained instruments and their application to Mendelian randomization with pleiotropy.

Genet Epidemiol 2019 Jun 12;43(4):373-401. Epub 2019 Jan 12.

Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/gepi.22184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537099PMC
June 2019

Association of TLR4 with Alzheimer's disease risk and presymptomatic biomarkers of inflammation.

Alzheimers Dement 2019 Jun 4. Epub 2019 Jun 4.

Douglas Mental Health University Institute, Montréal, Québec, Canada; Centre for the Studies in the Prevention of Alzheimer's Disease, Montréal, Québec, Canada.

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http://dx.doi.org/10.1016/j.jalz.2019.03.012DOI Listing
June 2019

No apparent effect of naproxen on CSF markers of innate immune activation.

Ann Clin Transl Neurol 2019 Jun 6;6(6):1127-1133. Epub 2019 Jun 6.

Faculty of Medicine McGill University Montréal Québec Canada.

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http://dx.doi.org/10.1002/acn3.788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562029PMC
June 2019

PET imaging of freely moving interacting rats.

Neuroimage 2019 05 2;191:560-567. Epub 2019 Mar 2.

Molecular Imaging Center Antwerp, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10538119193016
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http://dx.doi.org/10.1016/j.neuroimage.2019.02.064DOI Listing
May 2019

Machine Learning in Nuclear Medicine: Part 1-Introduction.

J Nucl Med 2019 Apr 7;60(4):451-458. Epub 2019 Feb 7.

Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; and

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http://dx.doi.org/10.2967/jnumed.118.223495DOI Listing
April 2019

INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease.

Neurology 2019 Apr 5;92(18):e2070-e2080. Epub 2019 Apr 5.

From the McGill Centre for Integrative Neuroscience, Montreal Neurological Institute (C.M.), and McGill University Research Centre for Studies in Aging (M.S., P.R.-N.), McGill University (P.-F.M., M.-E.L.-M., P.R.-N., J.P., P.E., J.B.); StoP-AD Centre (P.-F.M., J.T.-M., M.-E.L.-M., P.R.-N., J.P., P.E., J.B.), Douglas Mental Health University Institute Research Centre, Montréal, Canada; and John Hopkins University (J.L.), Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000007232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512884PMC
April 2019

A simplified radiosynthesis of [ F]MK-6240 for tau PET imaging.

J Labelled Comp Radiopharm 2019 Feb 19;62(2):109-114. Epub 2018 Dec 19.

Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://doi.wiley.com/10.1002/jlcr.3695
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http://dx.doi.org/10.1002/jlcr.3695DOI Listing
February 2019

In vivo metabotropic glutamate receptor type 5 abnormalities localize the epileptogenic zone in mesial temporal lobe epilepsy.

Ann Neurol 2019 Feb 20;85(2):218-228. Epub 2019 Jan 20.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ana.25404DOI Listing
February 2019

Astrocyte Biomarkers in Alzheimer's Disease.

Trends Mol Med 2019 Feb 2;25(2):77-95. Epub 2019 Jan 2.

Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Brain Institute (BraIns) of Rio Grande do Sul, Porto Alegre, Brazil; Website: www.zimmer-lab.org. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2018.11.006DOI Listing
February 2019

Cholinergic Potentiation Alters Perceptual Eye Dominance Plasticity Induced by a Few Hours of Monocular Patching in Adults.

Front Neurosci 2019 31;13:22. Epub 2019 Jan 31.

Laboratoire de Neurobiologie de la Cognition Visuelle, École d'Optométrie, Université de Montréal, Montréal, QC, Canada.

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http://dx.doi.org/10.3389/fnins.2019.00022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365463PMC
January 2019

Reduced resting-state functional connectivity of the basolateral amygdala to the medial prefrontal cortex in preweaning rats exposed to chronic early-life stress.

Brain Struct Funct 2018 Nov 21;223(8):3711-3729. Epub 2018 Jul 21.

Department of Psychiatry, McGill University, 6875 LaSalle Blvd, Montreal, QC, H4H 1R3, Canada.

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http://dx.doi.org/10.1007/s00429-018-1720-3DOI Listing
November 2018

The influence of language and culture on cognitive assessment tools in the diagnosis of early cognitive impairment and dementia.

Expert Rev Neurother 2018 Nov 10;18(11):859-869. Epub 2018 Oct 10.

b Alzheimer's Disease Research Unit , The McGill University Research Centre for Studies in Aging , Montreal , Canada.

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https://www.tandfonline.com/doi/full/10.1080/14737175.2018.1
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http://dx.doi.org/10.1080/14737175.2018.1532792DOI Listing
November 2018

Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia.

Mol Neurobiol 2018 Nov 9. Epub 2018 Nov 9.

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging (MCSA), Douglas Mental Health Research Institute, 6825, boul. LaSalle Blvd., Montréal, QC, H4H1R3, Canada.

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http://dx.doi.org/10.1007/s12035-018-1405-1DOI Listing
November 2018

Test-retest variability of [ C]ABP688 estimates of metabotropic glutamate receptor subtype 5 availability in humans.

Synapse 2018 09 20;72(9):e22041. Epub 2018 Jul 20.

Department of Psychiatry, McGill University, 1033 Pine Ave W, Montreal, Quebec, H3A 1A1, Canada.

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http://dx.doi.org/10.1002/syn.22041DOI Listing
September 2018

Optimal use of cholinergic drugs in Alzheimer's disease.

Brain 2018 Sep;141(9):e68

Alzheimer's Disease Research Unit, McGill University Research Center for Studies in Aging, Douglas Research Center and CIUSS de l'Ouest de l'Ile, Montreal, Canada.

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http://dx.doi.org/10.1093/brain/awy204DOI Listing
September 2018

PET/CT of Dementia.

AJR Am J Roentgenol 2018 08 27;211(2):246-259. Epub 2018 Jun 27.

9 Department of Medicine, Neurology Division, University of Toronto, and the Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, ON, Canada.

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http://dx.doi.org/10.2214/AJR.18.19822DOI Listing
August 2018

Fluid and imaging biomarkers for Alzheimer's disease: Where we stand and where to head to.

Exp Gerontol 2018 07 4;107:169-177. Epub 2018 Jan 4.

Medical Centre for the Elderly, University Hospital, University of Brasília (UnB), 70910-900 Brasília, DF, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2018.01.002DOI Listing
July 2018

In vivo quantification of neurofibrillary tangles with [F]MK-6240.

Alzheimers Res Ther 2018 07 31;10(1):74. Epub 2018 Jul 31.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, 6825 LaSalle Boulevard, Verdun, QC, H4H 1R3, Canada.

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http://dx.doi.org/10.1186/s13195-018-0402-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069775PMC
July 2018

Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease.

Eur J Nucl Med Mol Imaging 2018 06 2;45(6):1021-1030. Epub 2018 Feb 2.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC room 3149, Montreal, QC, H4H 1R3, Canada.

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http://dx.doi.org/10.1007/s00259-018-3933-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915512PMC
June 2018

Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies.

Stat Methods Med Res 2018 May 26;27(5):1331-1350. Epub 2016 Jul 26.

1 Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1177/0962280216660128DOI Listing
May 2018

Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.

Neurology 2018 Mar 14;90(11):e932-e939. Epub 2018 Feb 14.

From the Translational Neuroimaging Laboratory (J.T., K.P.N., T.A.P., S.M., M.S.K., H.S., M.S., A.L.B., P.R.-N.) and Alzheimer's Disease Research Unit (K.P.N., S.G., P.R.-N.), The McGill University Research Centre for Studies in Aging, Montreal, Canada; Department of Neurology (K.P.N.), National Neuroscience Institute, Singapore; Reference Center for Biological Markers of Dementia (BIODEM) (H.S.), University of Antwerp, Belgium; Center for Mind and Brain (I.C.W.), University of Sydney, Australia; Douglas Hospital Research Centre (V.N.), Department of Psychiatry (V.N.), and Department of Neurology and Neurosurgery (P.R.-N.), McGill University; and Montreal Neurological Institute (P.R.-N.), Canada.

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http://dx.doi.org/10.1212/WNL.0000000000005120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858945PMC
March 2018

Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease.

Hum Brain Mapp 2018 02 21;39(2):971-984. Epub 2017 Nov 21.

Cerebral Imaging Centre, Douglas Mental Health University Institute, Verdun, Quebec, Canada.

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http://dx.doi.org/10.1002/hbm.23897DOI Listing
February 2018

variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.

Neurol Genet 2018 Feb 30;4(1):e216. Epub 2018 Jan 30.

Translational Neuroimaging Laboratory (A.L.B., S.M., T.A.P., M.S., M.-S.K., P.R.-N.), and Alzheimer's Disease Research Unit (S.G., P.R.-N.), McGill University Research Centre for Studies in Aging, Montreal, Canada; CAPES Foundation (A.L.B.), Ministry of Education of Brazil, Brasília, Brazil; Rush Alzheimer's Disease Center (L.Y., D.A.B.), Rush University Medical Center, Chicago, IL; Department of Decision Sciences (A.L.), HEC Montreal, Montreal, Canada; Department of Epidemiology (A.L.), Biostatistics & Occupational Health, McGill University, Montreal, Canada; Department of Neurology and Neurosurgery (G.A.R., J.P., P.R.-N.), Douglas Hospital Research Centre (J.P., P.R.-N.), and Department of Psychiatry (J.P.), McGill University, Montreal, Canada; and Montreal Neurological Institute (G.A.R., P.R.-N.), Canada.

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http://dx.doi.org/10.1212/NXG.0000000000000216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820598PMC
February 2018

Imaging Alzheimer's disease pathophysiology with PET.

Dement Neuropsychol 2016 Apr-Jun;10(2):79-90

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging (MCSA), Douglas Mental Health Research Institute, Montreal, Canada.

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http://dx.doi.org/10.1590/S1980-5764-2016DN1002003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642398PMC
December 2017

Identifying incipient dementia individuals using machine learning and amyloid imaging.

Neurobiol Aging 2017 11 11;59:80-90. Epub 2017 Jul 11.

Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging (MCSA), Douglas Research Institute, McGill University, Montreal, Quebec, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; McGill University Research Centre for Studies in Aging (MCSA), Douglas Research Institute, McGill University, Montreal, Quebec, Canada; Douglas Research Institute, McGill University, Montreal, Quebec, Canada; Department of Psychiatry, McGill University, Montreal, Quebec, Canada; Department of Neurology & Neurosurgery, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.06.027DOI Listing
November 2017

Characterizing biomarker features of cognitively normal individuals with ventriculomegaly.

Alzheimers Dement (Amst) 2018 5;10:12-21. Epub 2017 Sep 5.

Alzheimer's Disease Research Unit, The McGill University Research Centre for Studies in Aging, McGill University, Montreal, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S23528729173004
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http://dx.doi.org/10.1016/j.dadm.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678356PMC
September 2017

Odor identification as a biomarker of preclinical AD in older adults at risk.

Neurology 2017 Jul 28;89(4):327-335. Epub 2017 Jun 28.

From the Centre for Studies on Prevention of AD (M.-E.L.-M., J.P., P.E., J.T.-M., J.F., P.R.-N., J.C.S.B.) and McGill Centre for Studies in Aging (P.R.-N.), Douglas Mental Health University Institute, McGill University, Faculty of Medicine, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000004159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574678PMC
July 2017

Synergistic interaction between amyloid and tau predicts the progression to dementia.

Alzheimers Dement 2017 Jun 23;13(6):644-653. Epub 2016 Dec 23.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Montreal, Canada; Montreal Neurological Institute, Montreal, Canada; AD Research Unit, The McGill University Research Centre for Studies in Aging, Montreal, Canada; McGill University, Montreal, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.11.005DOI Listing
June 2017

Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.

Neurology 2017 May 12;88(19):1814-1821. Epub 2017 Apr 12.

From the Translational Neuroimaging Laboratory (K.P.N., T.A.P., S.M., C.-O.C., A.L.B., M.S., M.S.K., P.R.-N.) and Alzheimer's Disease Research Unit (K.P.N., X.L., M.B., P.R.-N., S.G.), McGill University Research Centre for Studies in Aging, Montreal, Quebec, Canada; Department of Neurology (K.P.N., N.K.), National Neuroscience Institute, Singapore; Montreal Neurological Institute (P.R.-N.); Department of Neurology and Neurosurgery (P.R.-N.), McGill University, Montreal, Quebec, Canada; Department of Neurology (X.L.), The Second Affiliated Hospital of Chongqing Medical University, Chongqing; and Department of Neurology (M.B.), Yantai Yuhuangding Hospital Affiliated to Qingdao Medical University, Shandong, PR China.

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http://dx.doi.org/10.1212/WNL.0000000000003916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419982PMC
May 2017

[F]FDG PET signal is driven by astroglial glutamate transport.

Nat Neurosci 2017 Mar 30;20(3):393-395. Epub 2017 Jan 30.

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging (MCSA), Douglas Mental Health University Institute, Departments of Neurology and Neurosurgery, Psychiatry, and Pharmacology, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1038/nn.4492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378483PMC
March 2017

Monoamine oxidase B inhibitor, selegiline, reduces F-THK5351 uptake in the human brain.

Alzheimers Res Ther 2017 Mar 31;9(1):25. Epub 2017 Mar 31.

Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, 6825 LaSalle Boulevard, Verdun, Québec, H4H 1R3, Canada.

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http://dx.doi.org/10.1186/s13195-017-0253-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374697PMC
March 2017

The prevalence and biomarkers' characteristic of rapidly progressive Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database.

Alzheimers Dement (N Y) 2017 Jan 9;3(1):107-113. Epub 2017 Feb 9.

Alzheimer's Disease Research Unit, McGill Centre for Studies in Aging, McGill University, Douglas Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.trci.2016.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651370PMC
January 2017

Sensory-parietal cortical stimulation improves motor recovery in severe capsular infarct.

J Cereb Blood Flow Metab 2016 12 4;36(12):2211-2222. Epub 2015 Nov 4.

Department of Medical System Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea

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http://jcb.sagepub.com/content/early/2015/11/04/0271678X1560
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http://jcb.sagepub.com/lookup/doi/10.1177/0271678X15606136
Publisher Site
http://dx.doi.org/10.1177/0271678X15606136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363658PMC
December 2016

Remodeling of Neuronal Circuits After Reach Training in Chronic Capsular Stroke.

Neurorehabil Neural Repair 2016 11 18;30(10):941-950. Epub 2016 May 18.

Gwangju Institute of Science and Technology, Gwangju, Republic of Korea Presbyterian Medical Center, Jeonju, Republic of Korea

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http://dx.doi.org/10.1177/1545968316650282DOI Listing
November 2016

Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer's disease?

Transl Neurodegener 2016 16;5:20. Epub 2016 Nov 16.

McGill Centre for Studies in Aging, McGill University, Douglas Institute, 6825 Lasalle Boul, Montreal, QC H4H 1R3 Canada.

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http://dx.doi.org/10.1186/s40035-016-0067-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112745PMC
November 2016

Towards the PET radiotracer for p75 neurotrophin receptor: [(11)C]LM11A-24 shows biological activity in vitro, but unfavorable ex vivo and in vivo profile.

Bioorg Med Chem 2016 10 13;24(19):4759-4765. Epub 2016 Aug 13.

Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, QC H3A2B4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.08.020DOI Listing
October 2016

Deletion of the mu opioid receptor gene in mice reshapes the reward-aversion connectome.

Proc Natl Acad Sci U S A 2016 10 26;113(41):11603-11608. Epub 2016 Sep 26.

Advanced Molecular Imaging Center, Medical Physics, University Medical Center Freiburg, 79106 Freiburg, Germany; Engineering Science, Computer Science, and Imaging Laboratory, Integrative Multimodal Imaging in Healthcare, UMR 7357, University of Strasbourg, CNRS, 67000 Strasbourg, France; Department of Biophysics and Nuclear Medicine, University Hospital Strasbourg, 67000 Strasbourg, France

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http://dx.doi.org/10.1073/pnas.1601640113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068324PMC
October 2016

Canadian Consensus Guidelines on Use of Amyloid Imaging in Canada: Update and Future Directions from the Specialized Task Force on Amyloid imaging in Canada.

Can J Neurol Sci 2016 Jul 26;43(4):503-12. Epub 2016 Feb 26.

4Alzheimer's Disease Research Unit,McGill Center for Studies in Aging,Douglas Mental Health Research Institute,Montreal, QC,Canada.

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http://dx.doi.org/10.1017/cjn.2015.401DOI Listing
July 2016

VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis.

Front Neuroinform 2016 15;10:20. Epub 2016 Jun 15.

Translational Neuroimaging Laboratory, Departments of Neurology and Neurosurgery, McGill University Research Centre for Studies in Aging, Douglas Research Institute, McGill UniversityMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill UniversityMontreal, QC, Canada; McGill University Research Centre for Studies in Aging, Douglas Research Institute, McGill UniversityMontreal, QC, Canada; Douglas Hospital Research Center, Douglas Research Institute, McGill UniversityMontreal, QC, Canada; Department of Psychiatry, McGill UniversityMontreal, QC, Canada; Department of Neurology and Neurosurgery, McGill UniversityMontreal, QC, Canada.

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http://dx.doi.org/10.3389/fninf.2016.00020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908129PMC
July 2016

Test-retest resting-state fMRI in healthy elderly persons with a family history of Alzheimer's disease.

Sci Data 2015 13;2:150043. Epub 2015 Oct 13.

StoP-AD Centre, Centre for Studies on Prevention of Alzheimer's disease, 6875 LaSalle Boulevard , Montreal, QC H4H 1R3, Canada ; Centre de recherche de l'Institut Universitaire de Gériatrie de Montréal, 4545 Queen Mary , Montreal, QC H3W 1W5, Canada ; Université de Montréal, 2900 Boulevard Edouard-Montpetit , Montreal, QC H3T 1J4, Canada.

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http://dx.doi.org/10.1038/sdata.2015.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603392PMC
June 2016

In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD.

Brain Struct Funct 2016 Apr 18;221(3):1387-402. Epub 2015 Jan 18.

Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, McGill University, 6825 LaSalle Blvd, Montreal, QC, H4H 1R3, Canada.

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http://dx.doi.org/10.1007/s00429-014-0978-3DOI Listing
April 2016

Characterization of age/sex and the regional distribution of mGluR5 availability in the healthy human brain measured by high-resolution [(11)C]ABP688 PET.

Eur J Nucl Med Mol Imaging 2016 Jan 21;43(1):152-162. Epub 2015 Aug 21.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, 3801 University Street, Room 786, Montreal, Quebec, H3A 2B4, Canada.

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http://dx.doi.org/10.1007/s00259-015-3167-6DOI Listing
January 2016

Common Effects of Amnestic Mild Cognitive Impairment on Resting-State Connectivity Across Four Independent Studies.

Front Aging Neurosci 2015 24;7:242. Epub 2015 Dec 24.

Centre de Recherche de L'institut Universitaire de Gériatrie de MontréalMontreal, QC, Canada; Université de MontréalMontreal, QC, Canada.

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http://dx.doi.org/10.3389/fnagi.2015.00242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689788PMC
January 2016

Epistasis analysis links immune cascades and cerebral amyloidosis.

J Neuroinflammation 2015 Dec 1;12:227. Epub 2015 Dec 1.

Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, 6825 LaSalle Blvd, H4H 1R3, Montreal, QC, Canada.

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http://dx.doi.org/10.1186/s12974-015-0436-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666175PMC
December 2015

Imaging in vivo glutamate fluctuations with [(11)C]ABP688: a GLT-1 challenge with ceftriaxone.

J Cereb Blood Flow Metab 2015 Jul 25;35(7):1169-74. Epub 2015 Mar 25.

1] Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging, Douglas Mental Health University Institute, Verdun, Quebec, Canada [2] Alzheimer's Disease Research Unit, McGill Centre for Studies in Aging, McGill University, Montreal, Quebec, Canada [3] Montreal Neurological Institute (MNI), Montreal, Quebec, Canada.

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http://journals.sagepub.com/doi/10.1038/jcbfm.2015.35
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http://dx.doi.org/10.1038/jcbfm.2015.35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640271PMC
July 2015

Deficit in sustained attention following selective cholinergic lesion of the pedunculopontine tegmental nucleus in rat, as measured with both post-mortem immunocytochemistry and in vivo PET imaging with [¹⁸F]fluoroethoxybenzovesamicol.

Behav Brain Res 2015 Feb 22;278:107-14. Epub 2014 Sep 22.

Université du Québec à Montréal (UQAM), Canada; Douglas Mental Health University Institute, Canada; Montreal Neurological Institute (MNI), Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2014.09.021DOI Listing
February 2015

Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents.

ACS Chem Neurosci 2015 Feb 10;6(2):260-76. Epub 2014 Nov 10.

Experimental Medicine, Department of Medicine, McGill University , 1110 Pine Avenue West, Montreal, Quebec H3A 1A3, Canada.

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http://dx.doi.org/10.1021/cn500193fDOI Listing
February 2015

Resting state executive control network adaptations in amnestic mild cognitive impairment.

J Alzheimers Dis 2014 ;40(4):993-1004

Translational Neuroimaging Laboratory, Douglas Hospital, McGill University, Montreal, QC, Canada McGill Centre for Studies in Aging (MCSA), McGill University, Montreal, QC, Canada McConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, QC, Canada.

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http://dx.doi.org/10.3233/JAD-131574DOI Listing
January 2015

MicroPET imaging and transgenic models: a blueprint for Alzheimer's disease clinical research.

Trends Neurosci 2014 Nov 20;37(11):629-41. Epub 2014 Aug 20.

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging, Douglas Mental Health University Institute, Montreal, Quebec, Canada; PET unit, Montreal Neurological Institute (MNI), Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2014.07.002DOI Listing
November 2014

Use of amyloid PET across the spectrum of Alzheimer's disease: clinical utility and associated ethical issues.

Amyloid 2014 Sep 11;21(3):143-8. Epub 2014 Jun 11.

Translational Neuroimaging Laboratory (TNL), Douglas Mental Health University Institute , Montreal , Canada .

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http://dx.doi.org/10.3109/13506129.2014.926267DOI Listing
September 2014

Developments in Tau PET Imaging.

Can J Neurol Sci 2014 Sep;41(5):547-53

1Translational Neuroimaging Laboratory.

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https://www.cambridge.org/core/product/identifier/S031716711
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http://dx.doi.org/10.1017/cjn.2014.15DOI Listing
September 2014

Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer's disease model.

Neurobiol Dis 2014 Aug 5;68:126-36. Epub 2014 May 5.

Laboratory of Cerebrovascular Research, McGill University, Montréal, QC H3A 2B4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.04.018DOI Listing
August 2014

Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging.

J Neuroinflammation 2014 Jul 8;11:120. Epub 2014 Jul 8.

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging (MCSA), Douglas Mental Health University Institute, Montreal, QC H4H 1R3, Canada.

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http://dx.doi.org/10.1186/1742-2094-11-120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099095PMC
July 2014

Imaging biomarkers for amyloid: a new generation of probes and what lies ahead.

Int Psychogeriatr 2014 May 13;26(5):703-7. Epub 2014 Feb 13.

Alzheimer's Disease and Related Disorders Research Unit, McGill Center for Studies in Aging (MCSA), Douglas Mental Health Research Institute, Montreal, Canada Email:

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http://www.journals.cambridge.org/abstract_S1041610214000118
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May 2014

In vivo tracking of tau pathology using positron emission tomography (PET) molecular imaging in small animals.

Transl Neurodegener 2014 Mar 15;3(1). Epub 2014 Mar 15.

Translational Neuroimaging Laboratory (TNL), McGill Center for Studies in Aging, Douglas Mental Health University Institute, McGill University, 6875 La Salle Blv - FBC room 3149, Montreal, QC, H4H 1R3, Canada.

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http://dx.doi.org/10.1186/2047-9158-3-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995516PMC
March 2014

PET imaging with [¹⁸F]fluoroethoxybenzovesamicol ([¹⁸F]FEOBV) following selective lesion of cholinergic pedunculopontine tegmental neurons in rat.

Nucl Med Biol 2014 Jan 21;41(1):96-101. Epub 2013 Oct 21.

Université du Québec à Montreal (UQAM), Montreal, Quebec, Canada; Douglas Mental Health University Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.nucmedbio.2013.10.004DOI Listing
January 2014

Distinct increased metabotropic glutamate receptor type 5 (mGluR5) in temporal lobe epilepsy with and without hippocampal sclerosis.

Hippocampus 2013 Dec 23;23(12):1212-30. Epub 2013 Jul 23.

Department of Neurosciences and Behavior, Ribeirao Preto Medical School, University of Sao Paulo, Brazil; Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1002/hipo.22160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165311PMC
December 2013

Towards tropomyosin-related kinase B (TrkB) receptor ligands for brain imaging with PET: radiosynthesis and evaluation of 2-(4-[(18)F]fluorophenyl)-7,8-dihydroxy-4H-chromen-4-one and 2-(4-([N-methyl-(11)C]-dimethylamino)phenyl)-7,8-dihydroxy-4H-chromen-4-one.

Bioorg Med Chem 2013 Dec 19;21(24):7816-29. Epub 2013 Oct 19.

Department of Chemistry, Université de Montréal, PO Box 6128, Station Downtown, QC H3C 3J7, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, QC H3A 2B4, Canada.

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http://dx.doi.org/10.1016/j.bmc.2013.10.012DOI Listing
December 2013

Cholinergic Depletion in Alzheimer's Disease Shown by [ (18) F]FEOBV Autoradiography.

Int J Mol Imaging 2013 10;2013:205045. Epub 2013 Nov 10.

Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, Douglas Mental Health University Institute, Montreal, Canada H4H 1R3 ; Département de Psychologie, Université du Québec à Montreal (UQAM), Montreal, Canada H3C 3P8.

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http://dx.doi.org/10.1155/2013/205045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844185PMC
December 2013

Dementia: Disclosure of results to participants in dementia research.

Nat Rev Neurol 2013 Nov 22;9(11):608-9. Epub 2013 Oct 22.

McGill Centre for Studies in Aging, Douglas Mental Health Research Institute, 6825 LaSalle Boulevard, Montréal, QC H4H 1R3, Canada.

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http://dx.doi.org/10.1038/nrneurol.2013.213DOI Listing
November 2013

Impact of scale space search on age- and gender-related changes in MRI-based cortical morphometry.

Hum Brain Mapp 2013 Sep 16;34(9):2113-28. Epub 2012 Mar 16.

McConnell Brain Imaging Center, Montréal Neurological Institute, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1002/hbm.22050DOI Listing
September 2013

Early-onset familial Alzheimer's disease (EOFAD).

Can J Neurol Sci 2012 Jul;39(4):436-45

McGill Centre for Studies in Aging, McGill University Department of Neurology, Canada.

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July 2012

Test-retest stability of cerebral mGluR₅ quantification using [¹¹C]ABP688 and positron emission tomography in rats.

Synapse 2012 Jun 16;66(6):552-60. Epub 2012 Mar 16.

Translational Neuroimaging Laboratory, McGill Center for Studies in Aging, Douglas Research Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/syn.21542DOI Listing
June 2012

Prevention strategies for Alzheimer's disease.

Transl Neurodegener 2012 Jun 28;1(1):13. Epub 2012 Jun 28.

McGill Center for studies in Aging, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1186/2047-9158-1-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514088PMC
June 2012

Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits.

J Neurosci 2012 Apr;32(14):4705-15

Laboratory of Cerebrovascular Research, Montreal Neurological Institute, McGill University, Montréal, Québec H3A 2B4, Canada.

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http://dx.doi.org/10.1523/JNEUROSCI.0169-12.2012DOI Listing
April 2012

Reduced metabotropic glutamate receptor 5 in the Flinders Sensitive Line of rats, an animal model of depression: an autoradiographic study.

Brain Res Bull 2012 Mar 31;87(4-5):406-12. Epub 2012 Jan 31.

Cone Neurosurgical Research Laboratory, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S036192301200011
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http://dx.doi.org/10.1016/j.brainresbull.2012.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641045PMC
March 2012

Use of biomarkers in clinical trials of Alzheimer disease: from concept to application.

Mol Diagn Ther 2011 Dec;15(6):313-25

McGill Centre for Studies in Aging (MCSA), McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.2165/11595090-000000000-00000DOI Listing
December 2011

Age-related alterations in the modular organization of structural cortical network by using cortical thickness from MRI.

Neuroimage 2011 May 14;56(1):235-45. Epub 2011 Jan 14.

Montréal Neurological Institute, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2011.01.010DOI Listing
May 2011