Publications by authors named "Pedro Romero"

100Publications

Metabolic and epigenetic regulation of T-cell exhaustion.

Nat Metab 2020 Oct 21;2(10):1001-1012. Epub 2020 Sep 21.

Department of Fundamental Oncology, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s42255-020-00280-9DOI Listing
October 2020

Escasa información genómica en bases de datos públicas para investigar el SARS-CoV-2 en Latinoamérica.

Rev Peru Med Exp Salud Publica 2020 Apr-Jun;37(2):374. Epub 2020 Aug 28.

Facultad de Ciencias y Filosofía. Universidad Peruana Cayetano Heredia, Lima, Perú.

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http://dx.doi.org/10.17843/rpmesp.2020.372.5396DOI Listing
August 2020

Quantitative and qualitative impairments in dendritic cell subsets of patients with ovarian or prostate cancer.

Eur J Cancer 2020 Aug 23;135:173-182. Epub 2020 Jun 23.

Department of Oncology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.04.036DOI Listing
August 2020

An optimized antigen-protein fusion.

Nat Biomed Eng 2020 Jun;4(6):583-584

Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41551-020-0572-3DOI Listing
June 2020

Comment on "Genetic variants and source of introduction of SARS-CoV-2 in South America".

Authors:
Pedro E Romero

J Med Virol 2020 Jun 4. Epub 2020 Jun 4.

Department of Biological and Physiological Sciences, Faculty of Science and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru.

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http://dx.doi.org/10.1002/jmv.26122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300916PMC
June 2020

Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity.

Cell Mol Immunol 2020 Feb 13. Epub 2020 Feb 13.

Translational Tumor Immunology Group, Ludwig Cancer Research, University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.1038/s41423-020-0365-3DOI Listing
February 2020

miR-155 Overexpression in OT-1 CD8 T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen.

Mol Ther Oncolytics 2020 Mar 25;16:111-123. Epub 2019 Dec 25.

Department of Fundamental Oncology and Ludwig Cancer Center, Faculty of Biology and Medicine, University of Lausanne, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1016/j.omto.2019.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994712PMC
March 2020

Immunosuppressive Mediators Impair Proinflammatory Innate Lymphoid Cell Function in Human Malignant Melanoma.

Cancer Immunol Res 2020 04 4;8(4):556-564. Epub 2020 Feb 4.

Department of Oncology UNIL CHUV and Ludwig Institute for Cancer Research Lausanne, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1158/2326-6066.CIR-19-0504DOI Listing
April 2020

Distinct and shared gene expression for human innate versus adaptive helper lymphoid cells.

J Leukoc Biol 2020 Aug 4;108(2):723-737. Epub 2020 Feb 4.

Department of Oncology UNIL CHUV and Ludwig Institute for Cancer Research Lausanne, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/JLB.5MA0120-209RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496918PMC
August 2020

Recombinant fusion proteins for targeting dendritic cell subsets in therapeutic cancer vaccine.

Methods Enzymol 2020 18;632:521-543. Epub 2019 Dec 18.

Department of Fundamental Oncology, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.1016/bs.mie.2019.11.013DOI Listing
December 2019

Generation of affinity ranged antigen-expressing tumor cell lines.

Methods Enzymol 2020 18;632:503-519. Epub 2019 Dec 18.

Department of Oncology UNIL-CHUV, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.12.001DOI Listing
December 2019

Assessment of memory formation by metabolically engineered antigen-specific CD8 T cells.

Methods Enzymol 2020 20;631:77-90. Epub 2019 Nov 20.

Translational Tumor Immunology Group, Ludwig Cancer Research, University of Lausanne, Lausanne, Switzerland; Department of Oncology UNIL CHUV, University of Lausanne, Lausanne, Switzerland; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, China.

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http://dx.doi.org/10.1016/bs.mie.2019.10.021DOI Listing
November 2019

Detecting and analyzing murine innate lymphoid cells.

Methods Enzymol 2020 9;631:329-342. Epub 2019 Dec 9.

Department of Oncology UNIL CHUV, University of Lausanne, Lausanne, Switzerland; Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.10.022DOI Listing
December 2019

Moving cancer immunotherapy forward through the .

Authors:
Pedro Romero

J Immunother Cancer 2020 01 20;8(1). Epub 2019 Dec 20.

Department of Oncology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland

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http://dx.doi.org/10.1136/jitc-2019-000001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057440PMC
January 2020

Many-to-one binding by intrinsically disordered protein regions.

Pac Symp Biocomput 2020 ;25:159-170

Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 410 W. 10th St, HS5000, Indianapolis, IN46202, USA,

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January 2020

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Front Immunol 2019 6;10:925. Epub 2019 Jun 6.

Department of Oncology, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2019.00925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562565PMC
October 2020

F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer.

Eur J Nucl Med Mol Imaging 2019 Aug 18;46(9):1859-1868. Epub 2019 Jun 18.

Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s00259-019-04348-xDOI Listing
August 2019

Navigating metabolic pathways to enhance antitumour immunity and immunotherapy.

Nat Rev Clin Oncol 2019 07;16(7):425-441

Department of Fundamental Oncology, University of Lausanne, Lausanne, Vaud, Switzerland.

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http://dx.doi.org/10.1038/s41571-019-0203-7DOI Listing
July 2019

Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control.

Front Immunol 2019 26;10:294. Epub 2019 Feb 26.

Department of Fundamental Oncology, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2019.00294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399421PMC
September 2020

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.

Cell Stem Cell 2019 03;24(3):405-418.e7

Laboratory of Regenerative Hematopoiesis, Swiss Institute for Experimental Cancer Research (ISREC) & Institute of Bioengineering (IBI), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland; Service and Central Laboratory of Hematology, Departments of Oncology and of Laboratories, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909193006
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http://dx.doi.org/10.1016/j.stem.2019.02.012DOI Listing
March 2019

Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues.

Cancer Immunol Immunother 2019 03;68(3):529

Service of Clinical Pathology, Institute of Pathology, Lausanne University Hospital, rue du Bugnon 25, 1011, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s00262-019-02309-9DOI Listing
March 2019

Mechano-chemical decomposition of organic friction modifiers with multiple reactive centres induces superlubricity of ta-C.

Nat Commun 2019 01 11;10(1):151. Epub 2019 Jan 11.

Fraunhofer Institute for Mechanics of Materials IWM, MicroTribology Center μTC, Wöhlerstraße 11, 79108, Freiburg, Germany.

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http://www.nature.com/articles/s41467-018-08042-8
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http://dx.doi.org/10.1038/s41467-018-08042-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484224PMC
January 2019

CD73 expression in normal and pathological human hepatobiliopancreatic tissues.

Cancer Immunol Immunother 2019 Mar 4;68(3):467-478. Epub 2019 Jan 4.

Service of Clinical Pathology, Institute of Pathology, Lausanne University Hospital, rue du Bugnon 25, 1011, Lausanne, Switzerland.

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http://link.springer.com/10.1007/s00262-018-2290-1
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http://dx.doi.org/10.1007/s00262-018-2290-1DOI Listing
March 2019

Tumor Resident Memory T Cells: New Players in Immune Surveillance and Therapy.

Front Immunol 2018 11;9:2076. Epub 2018 Sep 11.

Department of Oncology, Faculty of Biology and Medicine, University of Lausanne, Épalinges, Switzerland.

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http://dx.doi.org/10.3389/fimmu.2018.02076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143788PMC
September 2019

Correction to: CART cells are prone to Fas- and DR5-mediated cell death.

J Immunother Cancer 2018 09 25;6(1):92. Epub 2018 Sep 25.

Department of Fundamental Oncology, Translational Tumor Immunology Group, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0410-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154881PMC
September 2018

CART cells are prone to Fas- and DR5-mediated cell death.

J Immunother Cancer 2018 07 13;6(1):71. Epub 2018 Jul 13.

Translational Tumor Immunology Group, Department of Fundamental Oncology, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-018-0385-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045821PMC
July 2018

PD-1 Blockade Unleashes Effector Potential of Both High- and Low-Affinity Tumor-Infiltrating T Cells.

J Immunol 2018 07 6;201(2):792-803. Epub 2018 Jun 6.

Department of Fundamental Oncology, Faculty of Biology and Medicine, University of Lausanne, 1066 Epalinges, Switzerland; and

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http://dx.doi.org/10.4049/jimmunol.1701644DOI Listing
July 2018

Sectoral networks and macroeconomic tail risks in an emerging economy.

PLoS One 2018 2;13(1):e0190076. Epub 2018 Jan 2.

Department of Mathematics, Universidad San Francisco de Quito, Quito, Pichincha, Ecuador.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190076PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749774PMC
February 2018

The Action of Red Cell Calcium Ions on Human Erythrophagocytosis .

Front Physiol 2017 4;8:1008. Epub 2017 Dec 4.

Laboratory of Membrane Physiology, Faculty of Sciences, Institute of Experimental Biology, Central University of Venezuela, Caracas, Venezuela.

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http://dx.doi.org/10.3389/fphys.2017.01008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722851PMC
December 2017

Metabolic Control of CD8 T Cell Fate Decisions and Antitumor Immunity.

Trends Mol Med 2018 01 12;24(1):30-48. Epub 2017 Dec 12.

Translational Tumor Immunology Group, Ludwig Cancer Research, University of Lausanne, Lausanne, Switzerland; Department of Fundamental Oncology, University of Lausanne, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.11.005DOI Listing
January 2018

TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.

JCI Insight 2017 Jul 20;2(14). Epub 2017 Jul 20.

Department of Oncology, Lausanne University Hospital Center (CHUV) and University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.1172/jci.insight.92570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518551PMC
July 2017

Rationale for immunological approaches to breast cancer therapy.

Breast 2018 Feb 17;37:187-195. Epub 2017 Jun 17.

Department of Fundamental Oncology, Ludwig Cancer Research Center at University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09609776173047
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http://dx.doi.org/10.1016/j.breast.2017.06.009DOI Listing
February 2018

NMRbox: A Resource for Biomolecular NMR Computation.

Biophys J 2017 Apr;112(8):1529-1534

Department of Molecular Biology and Biophysics, UConn Health, Farmington, Connecticut. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406371PMC
April 2017

The Vast Universe of T Cell Diversity: Subsets of Memory Cells and Their Differentiation.

Methods Mol Biol 2017 ;1514:1-17

Translational Tumor Immunology Group, Ludwig Cancer Research Center, University of Lausanne, Biopole III, CB02, Chemin des Boveresses 155, 1066, Epalinges, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-6548-9_1DOI Listing
January 2018

Increasing rigor in NMR-based metabolomics through validated and open source tools.

Curr Opin Biotechnol 2017 02 16;43:56-61. Epub 2016 Sep 16.

Biochemistry Department, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.copbio.2016.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305618PMC
February 2017

Positive selection on panpulmonate mitogenomes provide new clues on adaptations to terrestrial life.

BMC Evol Biol 2016 08 22;16(1):164. Epub 2016 Aug 22.

Senckenberg Biodiversity and Climate Research Centre (BiK-F), Senckenberganlage 25, 60325, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1186/s12862-016-0735-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994307PMC
August 2016

Piezoresistive Membrane Surface Stress Sensors for Characterization of Breath Samples of Head and Neck Cancer Patients.

Sensors (Basel) 2016 Jul 22;16(7). Epub 2016 Jul 22.

Department of Physics, University of Basel, Swiss Nanoscience Institute, Klingelbergstrasse 82, CH-4056 Basel, Switzerland.

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http://dx.doi.org/10.3390/s16071149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970191PMC
July 2016

IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner.

J Immunol 2016 07 27;197(1):85-96. Epub 2016 May 27.

INSERM Unit 1098, University of Franche-Comté, 25000 Besançon, France; Clinical Investigation Center for Biotherapies, 25000 Besançon, France; Etablissement Français du Sang, 25000 Besançon, France; Department of Medical Oncology, University Hospital of Besançon, 25000 Besançon, France; and

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http://dx.doi.org/10.4049/jimmunol.1501147DOI Listing
July 2016

Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells.

EBioMedicine 2016 Feb 16;4:50-61. Epub 2016 Jan 16.

Translational Tumor Immunology Group, Ludwig Cancer Research (LICR), University of Lausanne (UNIL), 1066 Epalinges, Vaud, Switzerland; Department of Oncology, Lausanne University Hospital (CHUV), 1011 Lausanne, Vaud, Switzerland.

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http://dx.doi.org/10.1016/j.ebiom.2016.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776068PMC
February 2016

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner.

Cell Rep 2016 Feb 21;14(5):1206-1217. Epub 2016 Jan 21.

Ludwig Center for Cancer Research, University of Lausanne, 1066 Epalinges, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.095DOI Listing
February 2016

Molecular phylogeny of the Ellobiidae (Gastropoda: Panpulmonata) supports independent terrestrial invasions.

Mol Phylogenet Evol 2016 Apr 24;97:43-54. Epub 2015 Dec 24.

Zoologisches Forschungsmuseum König, Adenauerallee 160, 53113 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ympev.2015.12.014DOI Listing
April 2016

[Comment on an article: comparative genomic analysis of peruvian strains of Mycobacterium tuberculosis].

Authors:
Pedro E Romero

Rev Peru Med Exp Salud Publica 2016 Oct-Dec;33(4):834-835

Senckenberg Biodiversity and Climate Research Centre, Fráncfort del Meno, Alemania.

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https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/2577
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http://dx.doi.org/10.17843/rpmesp.2016.334.2577DOI Listing
May 2017

Epitope located N-glycans impair the MHC-I epitope generation and presentation.

Electrophoresis 2016 06 3;37(11):1448-60. Epub 2016 Feb 3.

Institute of Biochemistry, Romanian Academy, Bucharest, Romania.

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http://dx.doi.org/10.1002/elps.201500449DOI Listing
June 2016

Introducing the clinical trials monitor: a new section of the journal for immunotherapy of cancer.

J Immunother Cancer 2015 20;3:49. Epub 2015 Oct 20.

Translational Tumor Immunology Group, Ludwig Cancer Research Center, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-015-0092-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617860PMC
October 2015

Erratum to: Improving protein order-disorder classification using charge-hydropathy plots.

BMC Bioinformatics 2015 Jul 31;16:241. Epub 2015 Jul 31.

Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1186/s12859-015-0646-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520057PMC
July 2015

In vitro activity of synthetic tetrahydroindeno[2,1-c]quinolines on Leishmania mexicana.

Parasitol Int 2015 Dec 3;64(6):479-83. Epub 2015 Jul 3.

Laboratorio de Fisiología de Membranas, Instituto de Biología Experimental, Facultad de Ciencias, Universidad Central de Venezuela, Apartado 47114, Caracas 1041A, Venezuela.

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https://linkinghub.elsevier.com/retrieve/pii/S13835769150010
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http://dx.doi.org/10.1016/j.parint.2015.06.011DOI Listing
December 2015

JITC launches a new section: commentary and editorials.

J Immunother Cancer 2015 24;3:28. Epub 2015 Jun 24.

Translational Tumor Immunology Group, Ludwig Cancer Research Center, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-015-0073-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479236PMC
June 2015

Surface softening in metal-ceramic sliding contacts: an experimental and numerical investigation.

ACS Nano 2015 Feb 28;9(2):1478-91. Epub 2015 Jan 28.

Fraunhofer-Institute for Mechanics of Materials IWM-MicroTribology Center μTC , Wöhlerstrasse 11, 79108 Freiburg, Germany.

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http://dx.doi.org/10.1021/nn505968mDOI Listing
February 2015

The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis.

Nat Commun 2014 Dec 3;5:5621. Epub 2014 Dec 3.

1] Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, 00100 Rome, Italy [2] Department of Dermatology, University Hospital CHUV, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/ncomms6621DOI Listing
December 2014

iNKT/CD1d-antitumor immunotherapy significantly increases the efficacy of therapeutic CpG/peptide-based cancer vaccine.

J Immunother Cancer 2014 18;2(1):39. Epub 2014 Nov 18.

Translational Tumor Immunology Group, Ludwig Center for Cancer Research, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s40425-014-0039-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243737PMC
November 2014

T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?

Nat Rev Immunol 2014 11 26;14(11):768-74. Epub 2014 Sep 26.

Swiss Vaccine Research Institute, Centre des laboratoires d'Epalinges, 1066 Epalinges, Switzerland, and the Division of Immunology and Allergy, Department of Medicine, Lausanne University Hospital, 1011 Lausanne, Switzerland.

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http://www.nature.com/articles/nri3740
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http://dx.doi.org/10.1038/nri3740DOI Listing
November 2014

Deciphering the unusual HLA-A2/Melan-A/MART-1-specific TCR repertoire in humans.

Eur J Immunol 2014 Sep;44(9):2567-70

Ludwig Cancer Research Center, Department of Oncology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/eji.201445004DOI Listing
September 2014

Coarse graining and localized plasticity between sliding nanocrystalline metals.

Phys Rev Lett 2014 Jul 16;113(3):036101. Epub 2014 Jul 16.

Fraunhofer Institute for Mechanics of Materials IWM, MicroTribology Center, Wöhlerstraße 11, 79108 Freiburg, Germany and University of Freiburg, Physics Department, Hermann-Herder-Straße 3, 79104 Freiburg, Germany.

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https://link.aps.org/doi/10.1103/PhysRevLett.113.036101
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http://dx.doi.org/10.1103/PhysRevLett.113.036101DOI Listing
July 2014