Publications by authors named "Paweł Terlecki"

2 Publications

  • Page 1 of 1

State of the art for gastric signet ring cell carcinoma: from classification, prognosis, and genomic characteristics to specified treatments.

Cancer Manag Res 2019 15;11:2151-2161. Epub 2019 Mar 15.

Department of Human Anatomy, Medical University of Lublin, Lublin, Poland,

Gastric cancer (GC) is responsible for 9% of cancer deaths worldwide. Over 950,000 new cases are diagnosed each year, and about 90% of them are in advanced stage, requiring chemotherapy. In Europe there has been research based on pre- and postoperative chemotherapy treatment, using 5-fluorouracil, epirubicin, cisplatin, capecitabine, and docetaxel. Chemotherapy significantly impairs the quality of life of patients; however, the final effects are not always satisfactory. There is scientific evidence that gastric mucus tumors and signet ring cell carcinomas have a pattern of specific signatures, that distinguish them from other gastric cancer subtypes, and may be associated with a poor response to systematic treatment. Signet ring cell carcinoma is less chemosensitive than others, and the increase in the percentage of signet ring cells correlates with resistance to chemotherapy. Perioperative chemotherapy in advanced signet ring cell carcinomas is an independent factor of poor prognosis and survival, which is explained by the toxicity of neoadjuvant treatment. Therefore, curative surgical resection enhanced by standardized lymphadenectomy remains the recommended gold standard in GC therapy. According to presented studies, early detection and aggressive treatments for this subtype of GC is a reasonable approach. This review paper is mostly addressed to physicians who are interested in updating to the state of the art concerning different subtypes of gastric carcinoma.
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http://dx.doi.org/10.2147/CMAR.S188622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421895PMC
March 2019

Solid-pseudopapillary neoplasm of the pancreas - comparisons between magnetic resonance and histological findings.

Pol J Pathol 2013 Oct;64(3):216-23

Prof. Justyna Szumiło MD, PhD, Department of Clinical Pathomorphology, Medical University of Lublin, Jaczewskiego 8, 20-059 Lublin, Poland, tel. +48 81 718 73 25, fax +48 81 718 73 24, e-mail:

Solid-pseudopapillary neoplasm is a rare pancreatic tumor typically observed in young adults. A new case of the tumor was diagnosed in a 22-year-old woman. An abnormal mass connected with the pancreatic body was found on ultrasound and computed tomography. Magnetic resonance revealed weak homogeneous contrast enhancement and a low ADC value (0.824 mm/s2; b1000). Primary radiological diagnosis suggested a solid pancreatic neoplasm, which was confirmed during histopathological assessment after resection of the pancreatic body with preservation of the spleen and normal drainage through the main pancreatic duct. Histological appearance of the solid-pseudopapillary neoplasm corresponded with its radiological morphology.
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http://dx.doi.org/10.5114/pjp.2013.38142DOI Listing
October 2013