Pavel Vodicka

Pavel Vodicka

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Pavel Vodicka

Publications by authors named "Pavel Vodicka"

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DNA Mismatch Repair Gene Variants in Sporadic Solid Cancers.

Int J Mol Sci 2020 Aug 3;21(15). Epub 2020 Aug 3.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, 14220 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21155561DOI Listing
August 2020

Exosomal microRNAs and other non-coding RNAs as colorectal cancer biomarkers: a review.

Mutagenesis 2020 07;35(3):243-260

Italian Institute for Genomic Medicine (IIGM), c/o IRCCS Candiolo, Candiolo, Turin, Italy.

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http://dx.doi.org/10.1093/mutage/gez038DOI Listing
July 2020

Telomere maintenance in interplay with DNA repair in pathogenesis and treatment of colorectal cancer.

Mutagenesis 2020 07;35(3):261-271

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, The Czech Academy of Sciences, Vídeňská, Praha, Czech Republic.

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http://dx.doi.org/10.1093/mutage/geaa005DOI Listing
July 2020

Distant Metastasis in Colorectal Cancer Patients-Do We Have New Predicting Clinicopathological and Molecular Biomarkers? A Comprehensive Review.

Int J Mol Sci 2020 Jul 24;21(15). Epub 2020 Jul 24.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21155255DOI Listing
July 2020

Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk.

Authors:
Minta Thomas Lori C Sakoda Michael Hoffmeister Elisabeth A Rosenthal Jeffrey K Lee Franzel J B van Duijnhoven Elizabeth A Platz Anna H Wu Christopher H Dampier Albert de la Chapelle Alicja Wolk Amit D Joshi Andrea Burnett-Hartman Andrea Gsur Annika Lindblom Antoni Castells Aung Ko Win Bahram Namjou Bethany Van Guelpen Catherine M Tangen Qianchuan He Christopher I Li Clemens Schafmayer Corinne E Joshu Cornelia M Ulrich D Timothy Bishop Daniel D Buchanan Daniel Schaid David A Drew David C Muller David Duggan David R Crosslin Demetrius Albanes Edward L Giovannucci Eric Larson Flora Qu Frank Mentch Graham G Giles Hakon Hakonarson Heather Hampel Ian B Stanaway Jane C Figueiredo Jeroen R Huyghe Jessica Minnier Jenny Chang-Claude Jochen Hampe John B Harley Kala Visvanathan Keith R Curtis Kenneth Offit Li Li Loic Le Marchand Ludmila Vodickova Marc J Gunter Mark A Jenkins Martha L Slattery Mathieu Lemire Michael O Woods Mingyang Song Neil Murphy Noralane M Lindor Ozan Dikilitas Paul D P Pharoah Peter T Campbell Polly A Newcomb Roger L Milne Robert J MacInnis Sergi Castellví-Bel Shuji Ogino Sonja I Berndt Stéphane Bézieau Stephen N Thibodeau Steven J Gallinger Syed H Zaidi Tabitha A Harrison Temitope O Keku Thomas J Hudson Veronika Vymetalkova Victor Moreno Vicente Martín Volker Arndt Wei-Qi Wei Wendy Chung Yu-Ru Su Richard B Hayes Emily White Pavel Vodicka Graham Casey Stephen B Gruber Robert E Schoen Andrew T Chan John D Potter Hermann Brenner Gail P Jarvik Douglas A Corley Ulrike Peters Li Hsu

Am J Hum Genet 2020 Jul 29. Epub 2020 Jul 29.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2020.07.006DOI Listing
July 2020

Methylation-Based Therapies for Colorectal Cancer.

Cells 2020 Jun 24;9(6). Epub 2020 Jun 24.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14 200 Prague, Czech Republic.

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http://dx.doi.org/10.3390/cells9061540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349319PMC
June 2020

DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome.

Cancers (Basel) 2020 Jun 28;12(7). Epub 2020 Jun 28.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic.

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http://dx.doi.org/10.3390/cancers12071713DOI Listing
June 2020

Colorectal Adenomas-Genetics and Searching for New Molecular Screening Biomarkers.

Int J Mol Sci 2020 May 5;21(9). Epub 2020 May 5.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14200 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21093260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247353PMC
May 2020

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer.

Authors:
Alexi N Archambault Yu-Ru Su Jihyoun Jeon Minta Thomas Yi Lin David V Conti Aung Ko Win Lori C Sakoda Iris Lansdorp-Vogelaar Elisabeth F P Peterse Ann G Zauber David Duggan Andreana N Holowatyj Jeroen R Huyghe Hermann Brenner Michelle Cotterchio Stéphane Bézieau Stephanie L Schmit Christopher K Edlund Melissa C Southey Robert J MacInnis Peter T Campbell Jenny Chang-Claude Martha L Slattery Andrew T Chan Amit D Joshi Mingyang Song Yin Cao Michael O Woods Emily White Stephanie J Weinstein Cornelia M Ulrich Michael Hoffmeister Stephanie A Bien Tabitha A Harrison Jochen Hampe Christopher I Li Clemens Schafmayer Kenneth Offit Paul D Pharoah Victor Moreno Annika Lindblom Alicja Wolk Anna H Wu Li Li Marc J Gunter Andrea Gsur Temitope O Keku Rachel Pearlman D Timothy Bishop Sergi Castellví-Bel Leticia Moreira Pavel Vodicka Ellen Kampman Graham G Giles Demetrius Albanes John A Baron Sonja I Berndt Stefanie Brezina Stephan Buch Daniel D Buchanan Antonia Trichopoulou Gianluca Severi María-Dolores Chirlaque Maria-José Sánchez Domenico Palli Tilman Kühn Neil Murphy Amanda J Cross Andrea N Burnett-Hartman Stephen J Chanock Albert de la Chapelle Douglas F Easton Faye Elliott Dallas R English Edith J M Feskens Liesel M FitzGerald Phyllis J Goodman John L Hopper Thomas J Hudson David J Hunter Eric J Jacobs Corinne E Joshu Sébastien Küry Sanford D Markowitz Roger L Milne Elizabeth A Platz Gad Rennert Hedy S Rennert Fredrick R Schumacher Robert S Sandler Daniela Seminara Catherine M Tangen Stephen N Thibodeau Amanda E Toland Franzel J B van Duijnhoven Kala Visvanathan Ludmila Vodickova John D Potter Satu Männistö Korbinian Weigl Jane Figueiredo Vicente Martín Susanna C Larsson Patrick S Parfrey Wen-Yi Huang Heinz-Josef Lenz Jose E Castelao Manuela Gago-Dominguez Victor Muñoz-Garzón Christoph Mancao Christopher A Haiman Lynne R Wilkens Erin Siegel Elizabeth Barry Ban Younghusband Bethany Van Guelpen Sophia Harlid Anne Zeleniuch-Jacquotte Peter S Liang Mengmeng Du Graham Casey Noralane M Lindor Loic Le Marchand Steven J Gallinger Mark A Jenkins Polly A Newcomb Stephen B Gruber Robert E Schoen Heather Hampel Douglas A Corley Li Hsu Ulrike Peters Richard B Hayes

Gastroenterology 2020 04 19;158(5):1274-1286.e12. Epub 2019 Dec 19.

Division of Epidemiology, Department of Population Health, New York University School of Medicine, New York, New York. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103489PMC
April 2020

Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses.

Gastroenterology 2020 04 27;158(5):1300-1312.e20. Epub 2019 Dec 27.

Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1053/j.gastro.2019.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152801PMC
April 2020

Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases in Colorectal Cancer Patients.

Int J Mol Sci 2020 Apr 2;21(7). Epub 2020 Apr 2.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21072473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177219PMC
April 2020

Diagnostic and prognostic impact of cell-free DNA in human cancers: Systematic review.

Mutat Res 2019 Jul - Sep;781:100-129. Epub 2019 May 11.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Albertov 4, Charles University, 12800 Prague, Czech Republic; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 32300 Pilsen, Czech Republic.

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http://dx.doi.org/10.1016/j.mrrev.2019.05.002DOI Listing
March 2020

5-fluorouracil and other fluoropyrimidines in colorectal cancer: Past, present and future.

Pharmacol Ther 2020 02 19;206:107447. Epub 2019 Nov 19.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Albertov 4, 128 00 Prague, Czech Republic; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00 Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2019.107447DOI Listing
February 2020

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis.

Nat Commun 2020 01 30;11(1):597. Epub 2020 Jan 30.

Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1038/s41467-020-14389-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992637PMC
January 2020

DNA repair capacity and response to treatment of colon cancer.

Pharmacogenomics 2019 11 6;20(17):1225-1233. Epub 2019 Nov 6.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, The Czech Academy of Sciences, Prague, Czech Republic.

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http://dx.doi.org/10.2217/pgs-2019-0070DOI Listing
November 2019

DNA methylation and chromatin modifiers in colorectal cancer.

Mol Aspects Med 2019 10 30;69:73-92. Epub 2019 Apr 30.

Experimental Tumorpathology, Institute of Pathology, University Hospital of Friedrich-Alexander-University Erlangen-Nürnberg, Universitätsstrasse 22, 91054, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.04.002DOI Listing
October 2019

Circulating biomarkers for early detection and clinical management of colorectal cancer.

Mol Aspects Med 2019 10 14;69:107-122. Epub 2019 Jun 14.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) / Hospital Clínic of Barcelona/ Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.06.002DOI Listing
October 2019

Lifestyle and dietary environmental factors in colorectal cancer susceptibility.

Mol Aspects Med 2019 10 28;69:2-9. Epub 2019 Jun 28.

International Agency for Research on Cancer (IARC-WHO), Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.06.005DOI Listing
October 2019

Fusobacterium nucleatum tumor DNA levels are associated with survival in colorectal cancer patients.

Eur J Clin Microbiol Infect Dis 2019 Oct 31;38(10):1891-1899. Epub 2019 Jul 31.

Cancer Biology and Therapeutics Group, School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Dublin, D04 V1W8, Ireland.

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http://dx.doi.org/10.1007/s10096-019-03649-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778531PMC
October 2019

Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer in vitro and in vivo.

Mutat Res 2019 09 3;845:403065. Epub 2019 Jun 3.

Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska, 1083, 142 20, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Albertov 4, 128 00, Prague, Czech Republic; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 323 00, Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2019.06.001DOI Listing
September 2019

DNA damage and repair measured by comet assay in cancer patients.

Mutat Res 2019 07 20;843:95-110. Epub 2019 May 20.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska, 1083, 142 20, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Albertov 4, 128 00, Prague, Czech Republic; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00, Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2019.05.009DOI Listing
July 2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 01 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Base excision repair capacity as a determinant of prognosis and therapy response in colon cancer patients.

DNA Repair (Amst) 2018 12 1;72:77-85. Epub 2018 Oct 1.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Albertov 4, 128 00, Prague, Czech Republic; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00, Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2018.09.006DOI Listing
December 2018

Genetic variation of acquired structural chromosomal aberrations.

Mutat Res Genet Toxicol Environ Mutagen 2018 Dec 19;836(Pt A):13-21. Epub 2018 May 19.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, D69120, Germany; Center for Primary Health Care Research, Lund University, Malmö, 214 28, Sweden.

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https://www.researchgate.net/publication/236938844_From_DNA_
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https://linkinghub.elsevier.com/retrieve/pii/S13835718183002
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http://dx.doi.org/10.1016/j.mrgentox.2018.05.014DOI Listing
December 2018

Circulating Cell-Free DNA and Colorectal Cancer: A Systematic Review.

Int J Mol Sci 2018 Oct 26;19(11). Epub 2018 Oct 26.

Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague, Czech Republic.

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http://www.mdpi.com/1422-0067/19/11/3356
Publisher Site
http://dx.doi.org/10.3390/ijms19113356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274807PMC
October 2018

lncRNAs in Non-Malignant Tissue Have Prognostic Value in Colorectal Cancer.

Int J Mol Sci 2018 Sep 8;19(9). Epub 2018 Sep 8.

Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 32300 Pilsen, Czech Republic.

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http://dx.doi.org/10.3390/ijms19092672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163783PMC
September 2018

Bleomycin-induced chromosomal damage and shortening of telomeres in peripheral blood lymphocytes of incident cancer patients.

Genes Chromosomes Cancer 2018 02 24;57(2):61-69. Epub 2017 Nov 24.

Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, 30605, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22508DOI Listing
February 2018

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

Authors:
Alison P Klein Brian M Wolpin Harvey A Risch Rachael Z Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J Childs Jason W Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A Arslan Ana Babic William R Bamlet Laura Beane-Freeman Sonja I Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G Chaffee Charles C Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J Michael M Gaziano Maria Gazouli Graham G Giles Edward Giovannucci Michael Goggins Gary E Goodman Phyllis J Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Eric J Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A Klein Manolis Kogevinas Charles Kooperberg Matthew H Kulke Juozas Kupcinskas Robert J Kurtz Daniel Laheru Stefano Landi Rita T Lawlor I-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L Milne Beatrice Mohelníková-Duchoňová Rachel E Neale John P Neoptolemos Ann L Oberg Sara H Olson Irene Orlow Claudio Pasquali Alpa V Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X Real Nathaniel Rothman Ghislaine Scelo Howard D Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D Thornquist Geoffrey S Tobias Stephen K Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M Petersen Laufey T Amundadottir

Nat Commun 2018 02 8;9(1):556. Epub 2018 Feb 8.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-02942-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805680PMC
February 2018

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

Lancet Neurol 2017 11;16(11):898-907

Institute of Neurogenomics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany; Neurologische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30327-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755468PMC
November 2017

Genotoxic and Cytotoxic Effects in Exfoliated Buccal and Nasal Cells of Chromium and Cobalt Exposed Electroplaters.

J Toxicol Environ Health A 2017 19;80(13-15):651-660. Epub 2017 May 19.

a Department of Medicine I, Institute of Cancer Research , Medical University of Vienna , Vienna , Austria.

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http://dx.doi.org/10.1080/15287394.2017.1286918DOI Listing
October 2017

Polymorphisms in Non-coding RNA Genes and Their Targets Sites as Risk Factors of Sporadic Colorectal Cancer.

Adv Exp Med Biol 2016 ;937:123-49

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00, Prague, Czech Republic.

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http://dx.doi.org/10.1007/978-3-319-42059-2_7DOI Listing
July 2017

DNA and chromosomal damage in medical workers exposed to anaesthetic gases assessed by the lymphocyte cytokinesis-block micronucleus (CBMN) assay. A critical review.

Mutat Res 2016 Oct - Dec;770(Pt A):26-34. Epub 2016 Apr 8.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00 Prague, Czech Republic; Human Genetics Foundation (HuGeF) Turin, via Nizza 52, 10126 Turin, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S13835742163002
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http://dx.doi.org/10.1016/j.mrrev.2016.04.003DOI Listing
May 2017

Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients.

Carcinogenesis 2017 01 1;38(1):28-39. Epub 2016 Nov 1.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, 14200 Prague, Czech Republic.

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http://dx.doi.org/10.1093/carcin/bgw114DOI Listing
January 2017

Genetic variation in the major mitotic checkpoint genes associated with chromosomal aberrations in healthy humans.

Cancer Lett 2016 10 15;380(2):442-6. Epub 2016 Jul 15.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835163040
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http://dx.doi.org/10.1016/j.canlet.2016.07.011DOI Listing
October 2016

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21.

Authors:
Mingfeng Zhang Zhaoming Wang Ofure Obazee Jinping Jia Erica J Childs Jason Hoskins Gisella Figlioli Evelina Mocci Irene Collins Charles C Chung Christopher Hautman Alan A Arslan Laura Beane-Freeman Paige M Bracci Julie Buring Eric J Duell Steven Gallinger Graham G Giles Gary E Goodman Phyllis J Goodman Aruna Kamineni Laurence N Kolonel Matthew H Kulke Núria Malats Sara H Olson Howard D Sesso Kala Visvanathan Emily White Wei Zheng Christian C Abnet Demetrius Albanes Gabriella Andreotti Lauren Brais H Bas Bueno-de-Mesquita Daniela Basso Sonja I Berndt Marie-Christine Boutron-Ruault Maarten F Bijlsma Hermann Brenner Laurie Burdette Daniele Campa Neil E Caporaso Gabriele Capurso Giulia Martina Cavestro Michelle Cotterchio Eithne Costello Joanne Elena Ugo Boggi J Michael Gaziano Maria Gazouli Edward L Giovannucci Michael Goggins Myron Gross Christopher A Haiman Manal Hassan Kathy J Helzlsouer Nan Hu David J Hunter Elzbieta Iskierka-Jazdzewska Mazda Jenab Rudolf Kaaks Timothy J Key Kay-Tee Khaw Eric A Klein Manolis Kogevinas Vittorio Krogh Juozas Kupcinskas Robert C Kurtz Maria T Landi Stefano Landi Loic Le Marchand Andrea Mambrini Satu Mannisto Roger L Milne Rachel E Neale Ann L Oberg Salvatore Panico Alpa V Patel Petra H M Peeters Ulrike Peters Raffaele Pezzilli Miquel Porta Mark Purdue J Ramón Quiros Elio Riboli Nathaniel Rothman Aldo Scarpa Ghislaine Scelo Xiao-Ou Shu Debra T Silverman Pavel Soucek Oliver Strobel Malin Sund Ewa Małecka-Panas Philip R Taylor Francesca Tavano Ruth C Travis Mark Thornquist Anne Tjønneland Geoffrey S Tobias Dimitrios Trichopoulos Yogesh Vashist Pavel Vodicka Jean Wactawski-Wende Nicolas Wentzensen Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Charles Kooperberg Harvey A Risch Eric J Jacobs Donghui Li Charles Fuchs Robert Hoover Patricia Hartge Stephen J Chanock Gloria M Petersen Rachael S Stolzenberg-Solomon Brian M Wolpin Peter Kraft Alison P Klein Federico Canzian Laufey T Amundadottir

Oncotarget 2016 Oct;7(41):66328-66343

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.18632/oncotarget.11041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340084PMC
October 2016

Epigenome-wide analysis of DNA methylation reveals a rectal cancer-specific epigenomic signature.

Epigenomics 2016 09 16;8(9):1193-207. Epub 2016 Aug 16.

Department of Laboratory Medicine, Örebro University; Örebro, Sweden.

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http://dx.doi.org/10.2217/epi-2016-0044DOI Listing
September 2016

The focus on sample quality: Influence of colon tissue collection on reliability of qPCR data.

Sci Rep 2016 07 7;6:29023. Epub 2016 Jul 7.

Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.1038/srep29023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935944PMC
July 2016

Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes.

PLoS One 2015 30;10(7):e0134463. Epub 2015 Jul 30.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine Charles University, Prague, Czech Republic.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520609PMC
May 2016

Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

PLoS One 2014 28;9(10):e111061. Epub 2014 Oct 28.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Center of Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111061PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211713PMC
January 2016

TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.

Int J Cancer 2015 Nov 19;137(9):2175-83. Epub 2015 Jun 19.

Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548797PMC
November 2015

Interactions of DNA repair gene variants modulate chromosomal aberrations in healthy subjects.

Carcinogenesis 2015 Nov 8;36(11):1299-306. Epub 2015 Sep 8.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany, Center for Primary Health Care Research, Lund University, 20506 Malmö, Sweden and.

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http://dx.doi.org/10.1093/carcin/bgv127DOI Listing
November 2015

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.

Nat Genet 2015 Aug 22;47(8):911-6. Epub 2015 Jun 22.

1] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. [2] Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ng.3341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520746PMC
August 2015

Structural chromosomal aberrations as potential risk markers in incident cancer patients.

Mutagenesis 2015 Jul 23;30(4):557-63. Epub 2015 Mar 23.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic, Institute of Biology and Medical Genetics, 1st Faculty of Medicine, Charles University in Prague, 128 00 Prague, Czech Republic,

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http://dx.doi.org/10.1093/mutage/gev018DOI Listing
July 2015

Synchronous gastric and sebaceous cancers, a rare manifestation of MLH1-related Muir-Torre syndrome.

Int J Clin Exp Pathol 2014 15;7(8):5196-202. Epub 2014 Jul 15.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic Prague.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152087PMC
June 2015

Metabolic gene variants associated with chromosomal aberrations in healthy humans.

Genes Chromosomes Cancer 2015 Apr 27;54(4):260-6. Epub 2015 Jan 27.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1002/gcc.22239DOI Listing
April 2015

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression.

BMC Cancer 2015 Apr 30;15:329. Epub 2015 Apr 30.

Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/s12885-015-1327-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417244PMC
April 2015

Telomere length in circulating lymphocytes: Association with chromosomal aberrations.

Genes Chromosomes Cancer 2015 Mar 27;54(3):194-6. Epub 2014 Nov 27.

Department of Molecular Genetic Epidemiology, German Cancer Research Center Heidelberg, (DKFZ), Im Neuenheimer Feld 580, 69121, Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1002/gcc.22225DOI Listing
March 2015

Polymorphisms in microRNA genes as predictors of clinical outcomes in colorectal cancer patients.

Carcinogenesis 2015 Jan 3;36(1):82-6. Epub 2014 Nov 3.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, 14200 Prague, Czech Republic, Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, 12108 Prague, Czech Republic.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgu224DOI Listing
January 2015

Histological aspects of the small intestine under variable feed restriction: The effects of short and intense restriction on a growing rabbit model.

Exp Ther Med 2014 Nov 21;8(5):1623-1627. Epub 2014 Aug 21.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Science of the Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.3892/etm.2014.1924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186336PMC
November 2014

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.

Authors:
Brian M Wolpin Cosmeri Rizzato Peter Kraft Charles Kooperberg Gloria M Petersen Zhaoming Wang Alan A Arslan Laura Beane-Freeman Paige M Bracci Julie Buring Federico Canzian Eric J Duell Steven Gallinger Graham G Giles Gary E Goodman Phyllis J Goodman Eric J Jacobs Aruna Kamineni Alison P Klein Laurence N Kolonel Matthew H Kulke Donghui Li Núria Malats Sara H Olson Harvey A Risch Howard D Sesso Kala Visvanathan Emily White Wei Zheng Christian C Abnet Demetrius Albanes Gabriella Andreotti Melissa A Austin Richard Barfield Daniela Basso Sonja I Berndt Marie-Christine Boutron-Ruault Michelle Brotzman Markus W Büchler H Bas Bueno-de-Mesquita Peter Bugert Laurie Burdette Daniele Campa Neil E Caporaso Gabriele Capurso Charles Chung Michelle Cotterchio Eithne Costello Joanne Elena Niccola Funel J Michael Gaziano Nathalia A Giese Edward L Giovannucci Michael Goggins Megan J Gorman Myron Gross Christopher A Haiman Manal Hassan Kathy J Helzlsouer Brian E Henderson Elizabeth A Holly Nan Hu David J Hunter Federico Innocenti Mazda Jenab Rudolf Kaaks Timothy J Key Kay-Tee Khaw Eric A Klein Manolis Kogevinas Vittorio Krogh Juozas Kupcinskas Robert C Kurtz Andrea LaCroix Maria T Landi Stefano Landi Loic Le Marchand Andrea Mambrini Satu Mannisto Roger L Milne Yusuke Nakamura Ann L Oberg Kouros Owzar Alpa V Patel Petra H M Peeters Ulrike Peters Raffaele Pezzilli Ada Piepoli Miquel Porta Francisco X Real Elio Riboli Nathaniel Rothman Aldo Scarpa Xiao-Ou Shu Debra T Silverman Pavel Soucek Malin Sund Renata Talar-Wojnarowska Philip R Taylor George E Theodoropoulos Mark Thornquist Anne Tjønneland Geoffrey S Tobias Dimitrios Trichopoulos Pavel Vodicka Jean Wactawski-Wende Nicolas Wentzensen Chen Wu Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Robert Hoover Patricia Hartge Charles Fuchs Stephen J Chanock Rachael S Stolzenberg-Solomon Laufey T Amundadottir

Nat Genet 2014 Sep 3;46(9):994-1000. Epub 2014 Aug 3.

1] Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. [2].

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http://dx.doi.org/10.1038/ng.3052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191666PMC
September 2014

HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients.

Carcinogenesis 2014 Jul 28;35(7):1510-5. Epub 2014 Feb 28.

Institute of Experimental Medicine, ASCR, Prague 14220, Czech Republic, Institute of Biology and Medical Genetics, First Medical Faculty, Charles University, Prague 12000, Czech Republic,

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http://dx.doi.org/10.1093/carcin/bgu055DOI Listing
July 2014

Variations in mismatch repair genes and colorectal cancer risk and clinical outcome.

Mutagenesis 2014 Jul 22;29(4):259-65. Epub 2014 Apr 22.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14200 Prague, Czech Republic, Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Katerinska 32, 12800 Prague, Czech Republic.

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http://dx.doi.org/10.1093/mutage/geu014DOI Listing
July 2014

Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors.

Cancer Causes Control 2014 Jun 5;25(6):759-69. Epub 2014 Apr 5.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s10552-014-0379-1DOI Listing
June 2014

Functional evaluation of DNA repair in human biopsies and their relation to other cellular biomarkers.

Front Genet 2014 23;5:116. Epub 2014 May 23.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine ASCR Prague, Czech Republic ; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University Prague, Czech Republic.

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http://dx.doi.org/10.3389/fgene.2014.00116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033188PMC
June 2014

Both genetic and dietary factors underlie individual differences in DNA damage levels and DNA repair capacity.

DNA Repair (Amst) 2014 Apr 6;16:66-73. Epub 2014 Mar 6.

Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2014.01.016DOI Listing
April 2014

Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.

Mol Biol Rep 2013 Oct 25;40(10):5921-9. Epub 2013 Sep 25.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 14200, Prague 4, Czech Republic.

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http://dx.doi.org/10.1007/s11033-013-2699-8DOI Listing
October 2013