Pavel Sumazin

Pavel Sumazin

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Pavel Sumazin

Pavel Sumazin

Publications by authors named "Pavel Sumazin"

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47Publications

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Epitranscriptomics: Correlation of N6-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats.

PLoS One 2019 17;14(1):e0203566. Epub 2019 Jan 17.

Department of Immunology and Microbiology and Department of Neuroscience, The Scripps Research Institute, La Jolla, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203566PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336335PMC
September 2019

Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death.

Int J Radiat Oncol Biol Phys 2019 Aug 16. Epub 2019 Aug 16.

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.08.011DOI Listing
August 2019

TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.

Am J Pathol 2019 May 19;189(5):1077-1090. Epub 2019 Feb 19.

Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, San Francisco, California. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526503PMC
May 2019

LIN28 Selectively Modulates a Subclass of Let-7 MicroRNAs.

Mol Cell 2018 07;71(2):271-283.e5

Department of Systems Biology, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238216PMC
July 2018

The number of titrated microRNA species dictates ceRNA regulation.

Nucleic Acids Res 2018 05;46(9):4354-4369

Department of Systems Biology, Institute for Cancer Genetics, Herbert Irving Comprehensive Cancer Center, Center for Computational Biology and Bioinformatics, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1093/nar/gky286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961349PMC
May 2018

Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma.

Neuro Oncol 2018 03;20(4):506-518

Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1093/neuonc/nox182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909636PMC
March 2018

A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma.

Sci Rep 2017 12 19;7(1):17751. Epub 2017 Dec 19.

Divisions of Pediatric Surgery and Surgical Research, Michael E. DeBakey Department of Surgery, Texas Children's Surgical Oncology Program, Texas Children's Liver Tumor Program, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41598-017-17665-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736579PMC
December 2017

Erratum: A novel humanized mouse lacking murine p450 oxidoreductase for studying human drug metabolism.

Nat Commun 2017 10 17;8(1):984. Epub 2017 Oct 17.

Center for Cell and Gene Therapy, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41467-017-01314-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645338PMC
October 2017

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.

Nat Commun 2017 06 28;8(1):39. Epub 2017 Jun 28.

Center for Cell and Gene Therapy, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX-77030, USA.

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http://dx.doi.org/10.1038/s41467-017-00049-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489481PMC
June 2017

High-throughput validation of ceRNA regulatory networks.

BMC Genomics 2017 05 30;18(1):418. Epub 2017 May 30.

Columbia Department of Systems Biology, Center for Computational Biology and Bioinformatics, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 10032, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/s12864
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http://dx.doi.org/10.1186/s12864-017-3790-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450082PMC
May 2017

Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer.

J Hepatol 2016 08 23;65(2):325-33. Epub 2016 Apr 23.

Center for Cell and Gene Therapy, Stem Cells and Regenerative Medicine Center, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA; Graduate Program Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668139PMC
August 2016

MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas.

Oncogene 2014 Nov 25;33(48):5511-5522. Epub 2013 Nov 25.

Texas Children's Cancer Center, Department of Pediatric Hematology/Oncology, Houston, TX 77030.

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http://dx.doi.org/10.1038/onc.2013.493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032816PMC
November 2014

tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma.

Proc Natl Acad Sci U S A 2013 Jan 7;110(4):1404-9. Epub 2013 Jan 7.

Institute for Cancer Genetics and Herbert Irving Comprehensive Cancer Center, Department of Genetics and Development, Columbia University, New York, NY 10032, USA.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1206761110
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http://dx.doi.org/10.1073/pnas.1206761110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557069PMC
January 2013

Correlating measurements across samples improves accuracy of large-scale expression profile experiments.

Genome Biol 2009 30;10(12):R143. Epub 2009 Dec 30.

Joint Centers for Systems Biology, Columbia University, 2960 Broadway, New York, NY 10027-6900, USA.

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http://dx.doi.org/10.1186/gb-2009-10-12-r143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812950PMC
May 2010

A systems biology approach to transcription factor binding site prediction.

PLoS One 2010 Mar 26;5(3):e9878. Epub 2010 Mar 26.

Department of Biomedical Informatics (DBMI), Columbia University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009878PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845628PMC
March 2010

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma.

Proc Natl Acad Sci U S A 2009 Jul 23;106(27):11294-9. Epub 2009 Jun 23.

Institute for Cancer Genetics, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1073/pnas.0903854106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708681PMC
July 2009

Identification of the human mature B cell miRNome.

Immunity 2009 May 14;30(5):744-52. Epub 2009 May 14.

Institute of Cancer Genetics and Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.immuni.2009.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764486PMC
May 2009

ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes.

Proc Natl Acad Sci U S A 2009 Jan 31;106(1):244-9. Epub 2008 Dec 31.

Department of Biomedical Informatics, Joint Centers for Systems Biology, Columbia University, New York, NY 10032, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0806445106
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http://dx.doi.org/10.1073/pnas.0806445106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613038PMC
January 2009

Tissue-specific regulatory elements in mammalian promoters.

Mol Syst Biol 2007 16;3:73. Epub 2007 Jan 16.

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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http://msb.embopress.org/cgi/doi/10.1038/msb4100114
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http://dx.doi.org/10.1038/msb4100114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800356PMC
February 2007

DNA motifs in human and mouse proximal promoters predict tissue-specific expression.

Proc Natl Acad Sci U S A 2006 Apr 10;103(16):6275-80. Epub 2006 Apr 10.

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1073/pnas.0508169103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458868PMC
April 2006

Genome-wide prediction and analysis of function-specific transcription factor binding sites.

In Silico Biol 2004 ;4(4):395-410

Aventis Pharmaceuticals Inc., Route 202/206, Bridgewater, NJ 08807, USA.

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June 2005

Mining ChIP-chip data for transcription factor and cofactor binding sites.

Bioinformatics 2005 Jun;21 Suppl 1:i403-12

Cold Spring Harbor Laboratory 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1093/bioinformatics/bti1043DOI Listing
June 2005

Similarity of position frequency matrices for transcription factor binding sites.

Bioinformatics 2005 Feb 19;21(3):307-13. Epub 2004 Aug 19.

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1093/bioinformatics/bth480DOI Listing
February 2005

Identifying tissue-selective transcription factor binding sites in vertebrate promoters.

Proc Natl Acad Sci U S A 2005 Feb 24;102(5):1560-5. Epub 2005 Jan 24.

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11274, USA.

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http://dx.doi.org/10.1073/pnas.0406123102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC547828PMC
February 2005

DWE: discriminating word enumerator.

Bioinformatics 2005 Jan 27;21(1):31-8. Epub 2004 Aug 27.

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1093/bioinformatics/bth471DOI Listing
January 2005

Deconvolving sequence variation in mixed DNA populations.

J Comput Biol 2003 ;10(3-4):635-52

Genera Biosystems, 4 Research Drive, Bundoora, 3151 Victoria, Australia.

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http://dx.doi.org/10.1089/10665270360688237DOI Listing
March 2004