Pavel Draber, PhD - Institute of Molecular Genetics

Pavel Draber

PhD

Institute of Molecular Genetics

Prague | Czech Republic

Pavel Draber, PhD - Institute of Molecular Genetics

Pavel Draber

PhD

Introduction

Primary Affiliation: Institute of Molecular Genetics - Prague , Czech Republic

Research Interests:

Metrics

Number of Publications

45

Publications

Number of Profile Views

109

Profile Views

Number of Article Reads

210

Reads

Number of Citations

277

Citations

Top co-authors

Pavel Draber
Pavel Draber

Institute of Molecular Genetics

42
Vadym Sulimenko
Vadym Sulimenko

Institute of Molecular Genetics

23
Tetyana Sulimenko
Tetyana Sulimenko

Institute of Molecular Genetics

18
Christos D Katsetos
Christos D Katsetos

Drexel University College of Medicine

15
Agustin Legido
Agustin Legido

Drexel University College of Medicine

9
Stanislav Vinopal
Stanislav Vinopal

Institute of Molecular Genetics

6
Zuzana Hajkova
Zuzana Hajkova

Institute of Molecular Genetics

6
Petr Draber
Petr Draber

Institute of Molecular Genetics

6

Publications

45Publications

210Reads

277PubMed Central Citations

Estradiol dimer inhibits tubulin polymerization and microtubule dynamics.

J Steroid Biochem Mol Biol 2018 Oct 24;183:68-79. Epub 2018 May 24.

CZ-OPENSCREEN, Institute of Molecular Genetics, Czech Academy of Sciences, Vídeňská 1083, CZ-142 20 Prague 4, Czech Republic. Electronic address:

View Article
October 2018
22 Reads
3.630 Impact Factor

Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition.

Front Immunol 2018 9;9:1563. Epub 2018 Jul 9.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czechia.

View Article
July 2018
13 Reads

Expression of γ-tubulin in non-small cell lung cancer and effect on patient survival.

Histol Histopathol 2018 Jul 16:18027. Epub 2018 Jul 16.

Department of Pathology and Laboratory Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

View Article
July 2018
6 Reads
1 Citation
2.100 Impact Factor

γ-Tubulin has a conserved intrinsic property of self-polymerization into double stranded filaments and fibrillar networks.

Biochim Biophys Acta Mol Cell Res 2018 May 27;1865(5):734-748. Epub 2018 Feb 27.

Institute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague 4, Czech Republic. Electronic address:

View Article
May 2018
1 Read
2 Citations
5.020 Impact Factor

Regulation of microtubule nucleation mediated by γ-tubulin complexes.

Protoplasma 2017 May 10;254(3):1187-1199. Epub 2017 Jan 10.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Vídeňská 1083, 142 20, Prague 4, Czech Republic.

View Article
May 2017
1 Read
3 Citations
2.651 Impact Factor

Profilin connects actin assembly with microtubule dynamics.

Mol Biol Cell 2016 08 15;27(15):2381-93. Epub 2016 Jun 15.

Department of Molecular Biosciences, Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden

View Article
August 2016
5 Citations
4.470 Impact Factor

GIT1/βPIX signaling proteins and PAK1 kinase regulate microtubule nucleation.

Biochim Biophys Acta 2016 Jun 22;1863(6 Pt A):1282-97. Epub 2016 Mar 22.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, CZ-142 20 Prague 4, Czech Republic. Electronic address:

View Article
June 2016
5 Reads
1 Citation

Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma.

J Neuropathol Exp Neurol 2015 Jul;74(7):723-42

From the Departments of Biology of Cytoskeleton (ED, VS, TS, VS, PD) and Biology of the Nucleus (MS, PH), Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic; Department of Pediatrics (LD, ET, AL, CDK), Drexel University College of Medicine, Section of Pediatric Neurology and Neurooncology Program (AL, CDK), St. Christopher's Hospital for Children, and Department of Pathology and Laboratory Medicine (NFM, CDK) Drexel University College of Medicine, Philadelphia, Pennsylvania; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania (VC, AG); Department of Clinical Cytology, Sismanoglion General Hospital, Athens, Greece (NFM); Department of Pathology, KAT General Hospital, Athens, Greece (EM); Department of Pathology, Faculty Hospital Brno, Brno, Czech Republic (LK); and Gades Institute, Department of Pathology, University of Bergen, Haukeland Hospital, Bergen, Norway (SM).

View Article
July 2015
8 Reads
4 Citations
3.800 Impact Factor

Membrane-cytoskeleton dynamics in the course of mast cell activation.

Methods Mol Biol 2015 ;1220:219-37

Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, v.v.i., Vídeňská 1083, 142 20, Prague, Czech Republic,

View Article
June 2015
1 Read
1 Citation

Microtubule nucleation in mouse bone marrow-derived mast cells is regulated by the concerted action of GIT1/βPIX proteins and calcium.

J Immunol 2015 May 27;194(9):4099-111. Epub 2015 Mar 27.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, CZ-142 20 Prague 4, Czech Republic;

View Article
May 2015
6 Reads
4.922 Impact Factor

Microscopy assays for evaluation of mast cell migration and chemotaxis.

Methods Mol Biol 2014 ;1192:161-76

Laboratory of Signal Transduction Institute of Molecular Genetics, v.v.i., Academy of Sciences of the Czech Republic, Vídeňská 1083, 142 20, Prague 4, Czech Republic.

View Article
April 2015
3 Reads
2 Citations

Emerging microtubule targets in glioma therapy.

Semin Pediatr Neurol 2015 Mar 4;22(1):49-72. Epub 2015 Apr 4.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

View Article
March 2015
1 Read
7 Citations
1.883 Impact Factor

Stabilization of protein by freeze-drying in the presence of trehalose: a case study of tubulin.

Methods Mol Biol 2014 ;1129:443-58

Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics Academy of Sciences of the Czech Republic, v.v.i., Vídeňská 1083, 142 20, Prague, Czech Republic,

View Article
November 2014

Gold nanoparticle-based immuno-PCR for detection of tau protein in cerebrospinal fluid.

J Immunol Methods 2014 Apr 15;406:137-42. Epub 2014 Mar 15.

Laboratory of Signal Transduction, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, CZ-142 20, Prague 4, Czech Republic. Electronic address:

View Article
April 2014
4 Reads
2 Citations
2.005 Impact Factor

Quantification of α-tubulin isotypes by sandwich ELISA with signal amplification through biotinyl-tyramide or immuno-PCR.

J Immunol Methods 2013 Sep 10;395(1-2):63-70. Epub 2013 Jul 10.

Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, CZ-142 20 Prague 4, Czech Republic.

View Article
September 2013
4 Reads
2.005 Impact Factor

Mitochondrial dysfunction in gliomas.

Semin Pediatr Neurol 2013 Sep;20(3):216-27

Laboratory of the Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

View Article
September 2013
5 Citations
1.883 Impact Factor

Tubulins as therapeutic targets in cancer: from bench to bedside.

Curr Pharm Des 2012 ;18(19):2778-92

Department of Pediatrics, Drexel University College of Medicine, St. Christopher's Hospital for Children, 3601 A Street, Philadelphia, PA 19134, USA.

View Article
September 2012
7 Citations
3.452 Impact Factor

Overexpression of γ-tubulin in non-small cell lung cancer.

Histol Histopathol 2012 09;27(9):1183-94

Department of Pathology and Laboratory Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania 19134, USA.

View Article
September 2012
23 Reads
5 Citations
2.100 Impact Factor

Cytoskeleton in mast cell signaling.

Front Immunol 2012 25;3:130. Epub 2012 May 25.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic Prague, Czech Republic.

View Article
August 2012
12 Reads
12 Citations

γ-Tubulin 2 nucleates microtubules and is downregulated in mouse early embryogenesis.

PLoS One 2012 3;7(1):e29919. Epub 2012 Jan 3.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

View Article
May 2012
1 Read
6 Citations
3.234 Impact Factor

Nuclear γ-tubulin associates with nucleoli and interacts with tumor suppressor protein C53.

J Cell Physiol 2012 Jan;227(1):367-82

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Czech Republic.

View Article
January 2012
8 Reads
8 Citations
3.840 Impact Factor

Targeting βIII-tubulin in glioblastoma multiforme: from cell biology and histopathology to cancer therapeutics.

Anticancer Agents Med Chem 2011 Oct;11(8):719-28

Departments of Pediatrics, Pathology & Laboratory Medicine, Drexel University College of Medicine, St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, USA.

View Article
October 2011
1 Read
2 Citations
2.470 Impact Factor

STIM1-directed reorganization of microtubules in activated mast cells.

J Immunol 2011 Jan 15;186(2):913-23. Epub 2010 Dec 15.

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic.

View Article
January 2011
17 Reads
14 Citations
4.922 Impact Factor

Differential expression and cellular distribution of gamma-tubulin and betaIII-tubulin in medulloblastomas and human medulloblastoma cell lines.

J Cell Physiol 2010 May;223(2):519-29

Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA.

View Article
May 2010
4 Reads
10 Citations
3.840 Impact Factor

Recovery of tubulin functions after freeze-drying in the presence of trehalose.

Anal Biochem 2010 Feb 13;397(1):67-72. Epub 2009 Oct 13.

Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, CZ-142 20 Prague 4, Czech Republic.

View Article
February 2010
1 Citation
2.220 Impact Factor

Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cells.

BMC Plant Biol 2010 Feb 18;10:29. Epub 2010 Feb 18.

Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic.

View Article
February 2010
5 Citations
3.813 Impact Factor

Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. II. gamma-Tubulin.

J Cell Physiol 2009 Dec;221(3):514-20

Department of Pediatrics and Neurology, Drexel University College of Medicine and Section of Neurology, St Christopher's Hospital for Children, Philadelphia, Pennsylvania 19134, USA.

View Article
December 2009
1 Read
6 Citations
3.840 Impact Factor

Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. Class III beta-tubulin.

J Cell Physiol 2009 Dec;221(3):505-13

Department of Pediatrics and Neurology, Drexel University College of Medicine and Section of Neurology, St Christopher's Hospital for Children, Philadelphia, Pennsylvania 19134, USA.

View Article
December 2009
1 Read
13 Citations
3.840 Impact Factor

Tyrosine phosphorylation of plant tubulin.

Planta 2008 Dec 18;229(1):143-50. Epub 2008 Sep 18.

Institute of Cell Biology and Genetic Engineering, National Academy of Sciences of Ukraine, Acad. Zabolotny Str., 148, 03680 Kiev, Ukraine.

View Article
December 2008
5 Reads
9 Citations
3.263 Impact Factor

Regulation of microtubule nucleation from membranes by complexes of membrane-bound gamma-tubulin with Fyn kinase and phosphoinositide 3-kinase.

Biochem J 2008 Dec;416(3):421-30

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Vídenská 1083, 142 20 Prague 4, Czech Republic.

View Article
December 2008
6 Reads
15 Citations
4.400 Impact Factor

Expression of beta-tubulin epitope in human sperm with pathological spermiogram.

Fertil Steril 2007 Oct 30;88(4 Suppl):1120-8. Epub 2007 Apr 30.

Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

View Article
October 2007
7 Reads
6 Citations
4.590 Impact Factor

Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells.

Neurochem Res 2007 Aug 4;32(8):1387-98. Epub 2007 Apr 4.

Department of Pediatrics, Drexel University College of Medicine and St. Christopher's Hospital for Children, Philadelphia, PA 19134, USA.

View Article
August 2007
4 Reads
16 Citations
2.593 Impact Factor

Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases.

J Immunol 2006 Jun;176(12):7243-53

Department of Biology of Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague.

View Article
June 2006
1 Read
13 Citations
4.922 Impact Factor

Altered cellular distribution and subcellular sorting of gamma-tubulin in diffuse astrocytic gliomas and human glioblastoma cell lines.

J Neuropathol Exp Neurol 2006 May;65(5):465-77

Department of Pediatrics, Drexel University College of Medicine, St. Christopher's Hospital for Children, Philadelphia, Pennsylvania 19134, USA.

View Article
May 2006
6 Reads
8 Citations
3.800 Impact Factor

Complexes of gamma-tubulin with nonreceptor protein tyrosine kinases Src and Fyn in differentiating P19 embryonal carcinoma cells.

Exp Cell Res 2004 Aug;298(1):218-28

Institute of Molecular Genetics, Department of Biology of Cytoskeleton, Academy of Sciences of the Czech Republic, Prague 4.

View Article
August 2004
7 Reads
8 Citations
3.250 Impact Factor

gamma-Tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms.

Exp Cell Res 2004 May;295(2):375-86

Department of Biology of the Cytoskeleton, Institute of Molecular Genetics, Czech Academy of Sciences, CZ-14220 Prague, Czech Republic.

View Article
May 2004
5 Reads
4 Citations
3.250 Impact Factor

Distribution of gamma-tubulin in cellular compartments of higher plant cells.

Cell Biol Int 2003 ;27(3):167-9

Institute of Microbiology, Academy of Sciences of the Czech Republic, Vi;denská 1083, 142 20 4, Prague, Czech Republic

View Article
January 2004
1 Read
1.933 Impact Factor

Analysis of glial acidic fibrillary protein in the human entorhinal cortex during aging and in Alzheimer's disease.

Proteomics 2003 Aug;3(8):1476-85

Institut de Biologie Cellulaire et de Morphologie, Université de Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland.

View Article
August 2003
1 Read
21 Citations
3.810 Impact Factor

Differential subcellular localization of phosphorylated neurofilament and tau proteins in degenerating neurons of the human entorhinal cortex.

Neuroreport 2003 May;14(7):929-33

Institut de Biologie Cellulaire et de Morphologie, Rue du Bugnon 9, 1005 Lausanne, Switzerland.

View Article
May 2003
4 Reads
1.644 Impact Factor

Plant gamma-tubulin interacts with alphabeta-tubulin dimers and forms membrane-associated complexes.

Plant Cell 2003 Feb;15(2):465-80

Institute of Microbiology, Academy of Sciences of the Czech Republic, Vídeská 1083, 142 20 Prague 4, Czech Republic.

View Article
February 2003
1 Read
21 Citations
9.340 Impact Factor

Monoclonal antibodies KN-02 and KN-03 against the heavy chain of kinesin.

Hybrid Hybridomics 2002 Dec;21(6):457-62

Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Vídenská 1083, 142 20 Prague 4, Czech Republic.

View Article
December 2002

Association of brain gamma-tubulins with alpha beta-tubulin dimers.

Biochem J 2002 Aug;365(Pt 3):889-95

Institute of Molecular Genetics, Department of Biology of Cytoskeleton, Academy of Sciences of the Czech Republic, 142 20 Prague 4, Czech Republic.

View Article
August 2002
3 Reads
4 Citations
4.400 Impact Factor

Gamma-tubulin in chicken erythrocytes: changes in localization during cell differentiation and characterization of cytoplasmic complexes.

Dev Dyn 2002 Mar;223(2):229-40

Department of Biology of the Cytoskeleton, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

View Article
March 2002
5 Reads
1 Citation
2.380 Impact Factor

Top co-authors

Pavel Draber
Pavel Draber

Institute of Molecular Genetics

42
Vadym Sulimenko
Vadym Sulimenko

Institute of Molecular Genetics

23
Tetyana Sulimenko
Tetyana Sulimenko

Institute of Molecular Genetics

18
Christos D Katsetos
Christos D Katsetos

Drexel University College of Medicine

15
Agustin Legido
Agustin Legido

Drexel University College of Medicine

9
Stanislav Vinopal
Stanislav Vinopal

Institute of Molecular Genetics

6
Zuzana Hajkova
Zuzana Hajkova

Institute of Molecular Genetics

6
Petr Draber
Petr Draber

Institute of Molecular Genetics

6