Pauline M Rudd

Pauline M Rudd

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Pauline M Rudd

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IgG Fc glycosylation as an axis of humoral immunity in childhood.

J Allergy Clin Immunol 2020 Feb 24;145(2):710-713.e9. Epub 2019 Oct 24.

Division of Immunology, Boston Children's Hospital, Boston, Mass; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010538PMC
February 2020

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods.

Authors:
Maria Lorna A De Leoz David L Duewer Adam Fung Lily Liu Hoi Kei Yau Oscar Potter Gregory O Staples Kenichiro Furuki Ruth Frenkel Yunli Hu Zoran Sosic Peiqing Zhang Friedrich Altmann Clemens Gru Nwald-Grube Chun Shao Joseph Zaia Waltraud Evers Stuart Pengelley Detlev Suckau Anja Wiechmann Anja Resemann Wolfgang Jabs Alain Beck John W Froehlich Chuncui Huang Yan Li Yaming Liu Shiwei Sun Yaojun Wang Youngsuk Seo Hyun Joo An Niels-Christian Reichardt Juan Echevarria Ruiz Stephanie Archer-Hartmann Parastoo Azadi Len Bell Zsuzsanna Lakos Yanming An John F Cipollo Maja Pucic-Bakovic Jerko Štambuk Gordan Lauc Xu Li Peng George Wang Andreas Bock René Hennig Erdmann Rapp Marybeth Creskey Terry D Cyr Miyako Nakano Taiki Sugiyama Pui-King Amy Leung Paweł Link-Lenczowski Jolanta Jaworek Shuang Yang Hui Zhang Tim Kelly Song Klapoetke Rui Cao Jin Young Kim Hyun Kyoung Lee Ju Yeon Lee Jong Shin Yoo Sa-Rang Kim Soo-Kyung Suh Noortje de Haan David Falck Guinevere S M Lageveen-Kammeijer Manfred Wuhrer Robert J Emery Radoslaw P Kozak Li Phing Liew Louise Royle Paulina A Urbanowicz Nicolle H Packer Xiaomin Song Arun Everest-Dass Erika Lattová Samanta Cajic Kathirvel Alagesan Daniel Kolarich Toyin Kasali Viv Lindo Yuetian Chen Kudrat Goswami Brian Gau Ravi Amunugama Richard Jones Corné J M Stroop Koichi Kato Hirokazu Yagi Sachiko Kondo C T Yuen Akira Harazono Xiaofeng Shi Paula E Magnelli Brian T Kasper Lara Mahal David J Harvey Roisin O'Flaherty Pauline M Rudd Radka Saldova Elizabeth S Hecht David C Muddiman Jichao Kang Prachi Bhoskar Daniele Menard Andrew Saati Christine Merle Steven Mast Sam Tep Jennie Truong Takashi Nishikaze Sadanori Sekiya Aaron Shafer Sohei Funaoka Masaaki Toyoda Peter de Vreugd Cassie Caron Pralima Pradhan Niclas Chiang Tan Yehia Mechref Sachin Patil Jeffrey S Rohrer Ranjan Chakrabarti Disha Dadke Mohammedazam Lahori Chunxia Zou Christopher Cairo Béla Reiz Randy M Whittal Carlito B Lebrilla Lauren Wu Andras Guttman Marton Szigeti Benjamin G Kremkow Kelvin H Lee Carina Sihlbom Barbara Adamczyk Chunsheng Jin Niclas G Karlsson Jessica Örnros Göran Larson Jonas Nilsson Bernd Meyer Alena Wiegandt Emy Komatsu Helene Perreault Edward D Bodnar Nassur Said Yannis-Nicolas Francois Emmanuelle Leize-Wagner Sandra Maier Anne Zeck Albert J R Heck Yang Yang Rob Haselberg Ying Qing Yu William Alley Joseph W Leone Hua Yuan Stephen E Stein

Mol Cell Proteomics 2020 01 7;19(1):11-30. Epub 2019 Oct 7.

Mass Spectrometry Data Center, Biomolecular Measurement Division, Material Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Drive Gaithersburg, Maryland 20899.

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http://dx.doi.org/10.1074/mcp.RA119.001677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944243PMC
January 2020

A Robust and Versatile Automated Glycoanalytical Technology for Serum Antibodies and Acute Phase Proteins: Ovarian Cancer Case Study.

Mol Cell Proteomics 2019 11 30;18(11):2191-2206. Epub 2019 Aug 30.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Dublin 4, Ireland, A94X099.

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http://dx.doi.org/10.1074/mcp.RA119.001531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823853PMC
November 2019

GlycopeptideGraphMS: Improved Glycopeptide Detection and Identification by Exploiting Graph Theoretical Patterns in Mass and Retention Time.

Anal Chem 2019 06 23;91(11):7236-7244. Epub 2019 May 23.

Bioprocessing Technology Institute , 20 Biopolis Way #06-01 , Singapore 138668.

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http://dx.doi.org/10.1021/acs.analchem.9b00594DOI Listing
June 2019

Validation of an automated ultraperformance liquid chromatography IgG N-glycan analytical method applicable to classical galactosaemia.

Ann Clin Biochem 2018 Sep 13;55(5):593-603. Epub 2018 Mar 13.

2 National Centre for Inherited Metabolic Diseases, The Mater Misericordiae University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1177/0004563218762957DOI Listing
September 2018

Glycan characterization of the NIST RM monoclonal antibody using a total analytical solution: From sample preparation to data analysis.

MAbs 2017 Nov/Dec;9(8):1349-1359. Epub 2017 Sep 12.

a GlycoScience Group, NIBRT-The National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co. Dublin , Ireland.

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http://dx.doi.org/10.1080/19420862.2017.1377381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680791PMC
July 2018

Targeting Chondroitin Sulfate Glycosaminoglycans to Treat Cardiac Fibrosis in Pathological Remodeling.

Circulation 2018 06 25;137(23):2497-2513. Epub 2018 Jan 25.

Cardiovascular Research Institute, National University of Singapore (R.R.Z., M.A.-J., T.D., Y.Z., P.W., P.Y.L., R.S.Y.F.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.030353DOI Listing
June 2018

LC/MS-based Intact IgG and Released Glycan Analysis for Bioprocessing Applications.

Biotechnol J 2018 Apr 2;13(4):e1700185. Epub 2018 Feb 2.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore.

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http://dx.doi.org/10.1002/biot.201700185DOI Listing
April 2018

High-Throughput Analysis of the Plasma N-Glycome by UHPLC.

Methods Mol Biol 2017 ;1503:97-108

NIBRT GlycoScience Group, NIBRT-The National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co., Dublin, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-6493-2_8DOI Listing
January 2018

Databases and Associated Tools for Glycomics and Glycoproteomics.

Methods Mol Biol 2017 ;1503:235-264

Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Box 440, 405 30, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/978-1-4939-6493-2_18DOI Listing
January 2018

Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy.

Protein Cell 2018 01 8;9(1):47-62. Epub 2017 Jun 8.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.

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http://dx.doi.org/10.1007/s13238-017-0433-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777974PMC
January 2018

The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins.

Expert Rev Proteomics 2018 01 22;15(1):13-29. Epub 2017 Nov 22.

b Genos Glycoscience Research Laboratory , 10000 , Zagreb , Croatia.

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http://dx.doi.org/10.1080/14789450.2018.1404907DOI Listing
January 2018

Erratum: Improvement of Prostate Cancer Diagnosis by Detecting PSA Glycosylation-Specific Changes: Erratum.

Theranostics 2018 1;8(3):746-748. Epub 2018 Jan 1.

Biochemistry and Molecular Biology Unit. Department of Biology, University of Girona, Campus Montilivi, 17071, Girona, Spain.

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http://dx.doi.org/10.7150/thno.23906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771090PMC
January 2018

Aminoquinoline Fluorescent Labels Obstruct Efficient Removal of N-Glycan Core α(1-6) Fucose by Bovine Kidney α-l-Fucosidase (BKF).

J Proteome Res 2017 11;16(11):4237-4243

NIBRT GlycoScience Group, National Institute for Bioprocessing, Research and Training , Foster's Avenue, Mount Merrion, Blackrock, Co., Dublin, Ireland.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.7b00580
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http://dx.doi.org/10.1021/acs.jproteome.7b00580DOI Listing
November 2017

Improvement of Prostate Cancer Diagnosis by Detecting PSA Glycosylation-Specific Changes.

Theranostics 2016 24;6(8):1190-204. Epub 2016 May 24.

1. Biochemistry and Molecular Biology Unit. Department of Biology, University of Girona, Campus Montilivi, 17071, Girona, Spain.; 4. Biomedical Research Institute of Girona (IdIBGi). Dr. J. Trueta University Hospital, 17007, Girona, Spain.

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http://dx.doi.org/10.7150/thno.15226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893645PMC
October 2017

Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab.

Mol Cell Proteomics 2017 10 2;16(10):1770-1788. Epub 2017 Jun 2.

¶NIBRT-Glycoscience Group, NIBRT-The National Institute for Bioprocessing, Research and Training, Foster Avenue, Blackrock, County Dublin, Ireland.

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http://dx.doi.org/10.1074/mcp.M117.066944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629263PMC
October 2017

Serum N-glycome alterations in breast cancer during multimodal treatment and follow-up.

Mol Oncol 2017 10 24;11(10):1361-1379. Epub 2017 Jul 24.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Dublin, Ireland.

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http://dx.doi.org/10.1002/1878-0261.12105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623820PMC
October 2017

Comprehensive N-Glycan Profiling of Avian Immunoglobulin Y.

PLoS One 2016 26;11(7):e0159859. Epub 2016 Jul 26.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Dublin 4, Ireland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159859PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961449PMC
July 2017

Dengue Virus Glycosylation: What Do We Know?

Front Microbiol 2017 25;8:1415. Epub 2017 Jul 25.

Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, and Immunology program, Life Sciences Institute, National University of SingaporeSingapore, Singapore.

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http://dx.doi.org/10.3389/fmicb.2017.01415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524768PMC
July 2017

Advances in analytical methodologies to guide bioprocess engineering for bio-therapeutics.

Methods 2017 03 8;116:63-83. Epub 2016 Nov 8.

NIBRT GlycoScience Group, The National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2016.11.002DOI Listing
March 2017

Estrogens regulate glycosylation of IgG in women and men.

JCI Insight 2017 02 23;2(4):e89703. Epub 2017 Feb 23.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/jci.insight.89703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313059PMC
February 2017

Epigenetic regulation of glycosylation and the impact on chemo-resistance in breast and ovarian cancer.

Epigenetics 2016 Dec 30;11(12):845-857. Epub 2016 Sep 30.

a NIBRT GlycoScience Group , The National Institute for Bioprocessing Research and Training , Mount Merrion, Blackrock, Dublin , Ireland.

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http://dx.doi.org/10.1080/15592294.2016.1241932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193495PMC
December 2016

Fc gamma receptors: glycobiology and therapeutic prospects.

J Inflamm Res 2016 16;9:209-219. Epub 2016 Nov 16.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.2147/JIR.S121233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118039PMC
November 2016

Quantitative profiling of glycans and glycopeptides: an informatics' perspective.

Curr Opin Struct Biol 2016 10 11;40:70-80. Epub 2016 Aug 11.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore 138668, Singapore; National Institute for Bioprocessing Research & Training, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2016.07.022DOI Listing
October 2016

Pregnancy-Associated Changes of IgG and Serum N-Glycosylation in Camel (Camelus dromedarius).

J Proteome Res 2016 09 3;15(9):3255-65. Epub 2016 Aug 3.

GlycoScience Group, NIBRT-The National Institute for Bioprocessing Research and Training , Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.

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http://dx.doi.org/10.1021/acs.jproteome.6b00439DOI Listing
September 2016

Mass Spectrometric Quantification of N-Linked Glycans by Reference to Exogenous Standards.

J Proteome Res 2016 09 5;15(9):2969-80. Epub 2016 Aug 5.

National Institute for Bioprocessing Research and Training (NIBRT) , Dublin, Ireland.

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http://dx.doi.org/10.1021/acs.jproteome.6b00132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501980PMC
September 2016

IgG Glycome in Colorectal Cancer.

Clin Cancer Res 2016 06 1;22(12):3078-86. Epub 2016 Feb 1.

Genos Glycoscience Research Laboratory, Zagreb, Croatia. Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860729PMC
June 2016

Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs.

Drug Discov Today 2016 05 25;21(5):740-65. Epub 2016 Jan 25.

Bioprocessing Technology Institute, 20 Biopolis Way, #06-01 Centros, Singapore; NIBRT GlycoScience Group, NIBRT - The National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2016.01.006DOI Listing
May 2016

Comprehensive Profiling of Glycosphingolipid Glycans Using a Novel Broad Specificity Endoglycoceramidase in a High-Throughput Workflow.

Anal Chem 2016 05 13;88(9):4795-802. Epub 2016 Apr 13.

NIBRT GlycoScience Group, National Institute for Bioprocessing, Research and Training , Fosters Avenue, Mount Merrion, Blackrock, Dublin 4, Ireland.

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http://dx.doi.org/10.1021/acs.analchem.6b00259DOI Listing
May 2016

A carbohydrate-binding affinity ligand for the specific enrichment of glycoproteins.

J Chromatogr A 2016 Apr 19;1444:8-20. Epub 2016 Mar 19.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2016.03.049DOI Listing
April 2016

Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies.

Biotechnol J 2016 Mar 11;11(3):399-414. Epub 2015 Dec 11.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://doi.wiley.com/10.1002/biot.201500331
Publisher Site
http://dx.doi.org/10.1002/biot.201500331DOI Listing
March 2016

Biosimilarity Versus Manufacturing Change: Two Distinct Concepts.

Pharm Res 2016 Feb 17;33(2):261-8. Epub 2015 Sep 17.

National Institute for Bioprocessing Research & Training (NIBRT), Fosters Avenue, Mount Merrion, Blackrock, Co., Dublin, Ireland.

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http://dx.doi.org/10.1007/s11095-015-1790-3DOI Listing
February 2016

Serum N-glycan analysis in breast cancer patients--Relation to tumour biology and clinical outcome.

Mol Oncol 2016 Jan 19;10(1):59-72. Epub 2015 Aug 19.

Department of Computer Science, Technion, Haifa, Israel; Agilent Laboratories, Agilent Technologies, Tel-Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528923PMC
January 2016

Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines.

J Immunol Methods 2016 Jan 26;428:30-6. Epub 2015 Nov 26.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.jim.2015.11.009DOI Listing
January 2016

Serum N-Glycome Characterization in Patients with Resectable Periampullary Adenocarcinoma.

J Proteome Res 2015 Dec 17;14(12):5144-56. Epub 2015 Nov 17.

Department of Environmental and Health Studies, Faculty of Arts and Sciences, Telemark University College , 3800 Bo in Telemark, Norway.

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http://dx.doi.org/10.1021/acs.jproteome.5b00395DOI Listing
December 2015

GlycoBase and autoGU: resources for interpreting HPLC-glycan data.

Methods Mol Biol 2015 ;1273:17-28

Biomolecular Frontiers Research Centre, Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, 2109, Australia,

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http://dx.doi.org/10.1007/978-1-4939-2343-4_2DOI Listing
November 2015

N-Glycosylation of Serum IgG and Total Glycoproteins in MAN1B1 Deficiency.

J Proteome Res 2015 Oct 24;14(10):4402-12. Epub 2015 Sep 24.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training , Fosters Avenue, Mount Merrion, Blackrock, Dublin 4, Ireland.

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http://dx.doi.org/10.1021/acs.jproteome.5b00709DOI Listing
October 2015

Ultrahigh throughput, ultrafiltration-based n-glycomics platform for ultraperformance liquid chromatography (ULTRA(3)).

Anal Chem 2015 Aug 31;87(16):8316-22. Epub 2015 Jul 31.

NIBRT GlycoScience Group, NIBRT - The National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.

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http://dx.doi.org/10.1021/acs.analchem.5b01463DOI Listing
August 2015

GlycoProfileAssigner: automated structural assignment with error estimation for glycan LC data.

Bioinformatics 2015 Jul 26;31(13):2220-1. Epub 2015 Feb 26.

National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Co. Dublin, Ireland.

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http://dx.doi.org/10.1093/bioinformatics/btv129DOI Listing
July 2015

Identification of O-glycan Structures from Chicken Intestinal Mucins Provides Insight into Campylobactor jejuni Pathogenicity.

Mol Cell Proteomics 2015 Jun 16;14(6):1464-77. Epub 2015 Mar 16.

§School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Dublin, Ireland; ¶Department of Medical Biochemistry, Gothenburg University, Gothenburg, Sweden

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http://dx.doi.org/10.1074/mcp.M114.044867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458713PMC
June 2015

Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids.

Innate Immun 2015 Feb 3;21(2):175-93. Epub 2014 Mar 3.

Department of Integrative Structural and Computational Biology, and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA

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http://dx.doi.org/10.1177/1753425914524077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392886PMC
February 2015

The "sweet" side of the protein corona: effects of glycosylation on nanoparticle-cell interactions.

ACS Nano 2015 Feb 12;9(2):2157-66. Epub 2015 Feb 12.

Centre for BioNano Interactions, School of Chemistry and Chemical Biology, University College Dublin , Dublin 4, Ireland.

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http://dx.doi.org/10.1021/nn506060qDOI Listing
February 2015

Sialylation of N-linked glycans influences the immunomodulatory effects of IgM on T cells.

J Immunol 2015 Jan 24;194(1):151-7. Epub 2014 Nov 24.

Division of Nephrology and Dialysis, Bambino Gesù Children's Hospital-Scientific Institute, 00165 Rome, Italy;

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http://dx.doi.org/10.4049/jimmunol.1402025DOI Listing
January 2015

Galactosyltransferase 4 is a major control point for glycan branching in N-linked glycosylation.

J Cell Sci 2014 Dec 30;127(Pt 23):5014-26. Epub 2014 Sep 30.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland

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http://dx.doi.org/10.1242/jcs.151878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248093PMC
December 2014

Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions.

J Proteome Res 2014 Dec 11;13(12):5471-85. Epub 2014 Nov 11.

School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College , Pearse St. Dublin 2, Dublin, Ireland.

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http://dx.doi.org/10.1021/pr500414qDOI Listing
December 2014

GlycoDigest: a tool for the targeted use of exoglycosidase digestions in glycan structure determination.

Bioinformatics 2014 Nov 10;30(21):3131-3. Epub 2014 Jul 10.

Proteome Informatics Group, Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland, Biomolecular Frontiers Research Centre, Macquarie University, North Ryde, NSW 2109, Australia, National Institute for Bioprocessing Research and Training, GlycoScience Group, Dublin, Ireland, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, 40530 Gothenburg, Sweden and Section of Biology, University of Geneva, 1211 Geneva, Switzerland Proteome Informatics Group, Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland, Biomolecular Frontiers Research Centre, Macquarie University, North Ryde, NSW 2109, Australia, National Institute for Bioprocessing Research and Training, GlycoScience Group, Dublin, Ireland, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, 40530 Gothenburg, Sweden and Section of Biology, University of Geneva, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.1093/bioinformatics/btu425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609004PMC
November 2014

Glycosylation and Fc receptors.

Curr Top Microbiol Immunol 2014 ;382:165-99

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland,

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http://dx.doi.org/10.1007/978-3-319-07911-0_8DOI Listing
November 2014

The role and importance of glycosylation of acute phase proteins with focus on alpha-1 antitrypsin in acute and chronic inflammatory conditions.

J Proteome Res 2014 Jul 12;13(7):3131-43. Epub 2014 Jun 12.

Respiratory Research Division, Royal College of Surgeons in Ireland , Beaumont Hospital, Dublin 9, Ireland.

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http://dx.doi.org/10.1021/pr500146yDOI Listing
July 2014

Association of N-glycosylation with breast carcinoma and systemic features using high-resolution quantitative UPLC.

J Proteome Res 2014 May 11;13(5):2314-27. Epub 2014 Apr 11.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training , Fosters Avenue, Mount Merrion, Blackrock, Dublin 4, Ireland.

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http://dx.doi.org/10.1021/pr401092yDOI Listing
May 2014

Comparison of separation techniques for the elucidation of IgG N-glycans pooled from healthy mammalian species.

Carbohydr Res 2014 May 8;389:174-85. Epub 2014 Feb 8.

GlycoScience Group, NIBRT-The National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00086215140004
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http://dx.doi.org/10.1016/j.carres.2014.01.018DOI Listing
May 2014

A comparative study of free oligosaccharides in the milk of domestic animals.

Br J Nutr 2014 Apr;111(7):1313-28

NIBRT GlycoScience Group, National Institute for Bioprocessing, Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Dublin 4, Republic of Ireland.

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http://dx.doi.org/10.1017/S0007114513003772DOI Listing
April 2014

Increased outer arm and core fucose residues on the N-glycans of mutated alpha-1 antitrypsin protein from alpha-1 antitrypsin deficient individuals.

J Proteome Res 2014 Feb 13;13(2):596-605. Epub 2013 Dec 13.

Respiratory Research Division, Royal College of Surgeons in Ireland , Beaumont Hospital, Dublin 9, Ireland.

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http://dx.doi.org/10.1021/pr400752tDOI Listing
February 2014

N-glycan abnormalities in children with galactosemia.

J Proteome Res 2014 Feb 20;13(2):385-94. Epub 2013 Dec 20.

University College Dublin (UCD) , Clinical Research Centre, Mater Misericordiae University Hospital, Eccles Street, Dublin, Ireland.

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http://dx.doi.org/10.1021/pr4008305DOI Listing
February 2014

N- and O-glycosylation analysis of etanercept using liquid chromatography and quadrupole time-of-flight mass spectrometry equipped with electron-transfer dissociation functionality.

Anal Chem 2014 Jan 18;86(1):576-84. Epub 2013 Dec 18.

Late Stage Development, Pharmaceutical Life Sciences, Waters Corporation , Milford, Massachusetts 01757, United States.

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http://dx.doi.org/10.1021/ac402726hDOI Listing
January 2014

Glycosylation as a marker for inflammatory arthritis.

Cancer Biomark 2014 Jan;14(1):17-28

Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.3233/CBM-130373DOI Listing
January 2014

A HPLC-based glycoanalytical protocol allows the use of natural O-glycans derived from glycoproteins as substrates for glycosidase discovery from microbial culture.

Glycoconj J 2013 Nov 25;30(8):791-800. Epub 2013 Jun 25.

Dublin-Oxford Glycobiology Group, National Institute for Bioprocessing Research & Training, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1007/s10719-013-9483-9DOI Listing
November 2013

An automated robotic platform for rapid profiling oligosaccharide analysis of monoclonal antibodies directly from cell culture.

Anal Biochem 2013 Nov 16;442(1):10-8. Epub 2013 Jul 16.

National Institute of Bioprocessing Research and Training (NIBRT), Mount Merrion, Blackrock, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2013.07.005DOI Listing
November 2013

Glycosylation status of serum in inflammatory arthritis in response to anti-TNF treatment.

Rheumatology (Oxford) 2013 Sep 16;52(9):1572-82. Epub 2013 May 16.

Department of Rheumatology, Dublin Academic Medical Centre, Dublin 4, Ireland.

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http://dx.doi.org/10.1093/rheumatology/ket189DOI Listing
September 2013

Automated, high-throughput IgG-antibody glycoprofiling platform.

Anal Chem 2013 Sep 29;85(18):8841-9. Epub 2013 Aug 29.

NIBRT GlycoScience Group, NIBRT- The National Institute for Bioprocessing Research and Training , Fosters Avenue, Mount Merrion, Blackrock, Co. Dublin, Ireland.

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http://dx.doi.org/10.1021/ac402068rDOI Listing
September 2013

N-linked glycan structures of the human Fcγ receptors produced in NS0 cells.

J Proteome Res 2013 Aug 11;12(8):3721-37. Epub 2013 Jul 11.

NIBRT Glycobiology Group, National Institute for Bioprocessing Research and Training, Foster's Avenue, Mount Merrion, Blackrock, County Dublin, Ireland.

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http://dx.doi.org/10.1021/pr400344hDOI Listing
August 2013

The presence of outer arm fucose residues on the N-glycans of tissue inhibitor of metalloproteinases-1 reduces its activity.

J Proteome Res 2013 Aug 1;12(8):3547-60. Epub 2013 Jul 1.

Department of Biochemistry, College of Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1021/pr400276rDOI Listing
August 2013

Exploring the glycosylation of serum CA125.

Int J Mol Sci 2013 Jul 26;14(8):15636-54. Epub 2013 Jul 26.

NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.

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http://dx.doi.org/10.3390/ijms140815636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759877PMC
July 2013

Greedy feature selection for glycan chromatography data with the generalized Dirichlet distribution.

BMC Bioinformatics 2013 May 7;14:155. Epub 2013 May 7.

School of Mathematical Sciences, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/1471-2105-14-155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703279PMC
May 2013