Publications by authors named "Pauline Bataille"

5 Publications

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Performance of the Kleihauer Betke test in the prediction of neonatal anemia.

J Matern Fetal Neonatal Med 2020 Oct 26:1-7. Epub 2020 Oct 26.

Nantes University Hospital, Nantes, France.

Objectives: The aim of this study was to correlate antenatal Kleihauer (KT) test results with fetal hemoglobin at birth to find a threshold for predicting severe fetal anemia. The secondary objectives were to assess the impact of KT on obstetric management and to study the correlation between the middle cerebral artery peack systolic velocity and fetal anemia.

Results: One thousand forty-six KT were positive over the 10-year period, but only 147 were included from 88 patients, of which 17 fetuses were anemic. Demographic and obstetric characteristics were similar between anemic and non-anemic groups. As regards new-born, there was a higher risk of prematurity among anemic as long as a lower birth rate in accordance. While a negative correlation was observed between KT and hemoglobin at birth, no KT upper threshold could be found that was both sensitive and specific. In addition, there was no case of fetal anemia when KT was repeated, even though it increased. KT showed little usefulness in obstetrics management to help improving neonatal care for anemia. Conversely, the MCA PSV demonstrated good performance in this matter and the ROC curve area was 0.91 (figure).

Discussion: Feto-maternal hemorrhage is a rare but grave pathology which could lead to anemia. The most common clinical sign is reduced fetal movement and it was the main indication to perform a KT. Cardiotocography patterns suggestive of anemia are sinusoidal, micro-oscillatory and non-reactive monitoring. Ultrasound features were polyhydramnios, hydrop fetalis and increased MCA peack systolic velocity. KT was correlated with MCA PSV and with hemoglobin level at birth. However, the latter showed a better diagnostic performance. MCA PSV measurement is a powerful test to screen for fetal anemia, and should be part of the regular training of obstetricians. Indeed, this technic gives immediate and reliable results, while those of KT are delayed.

Conclusion: The KT should not be used as a tool to screen for fetal anemia but rather as a test to explain a fetal anemia. However, the MCA PSV is reliable in this matter and give immediate result, thus obstetrician should be trained to routinely perform it.
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http://dx.doi.org/10.1080/14767058.2020.1837768DOI Listing
October 2020

An unsual case of palmoplantar keratoderma.

Pediatr Dermatol 2020 Jan;37(1):e17-e19

Department of Dermatology, Reference Centre for Genodermatoses and Rare Skin Disease (MAGEC), Hopital Universitaire Necker-Enfants Malades, APHP, Paris, France.

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http://dx.doi.org/10.1111/pde.14038DOI Listing
January 2020

Clinical variability and probable founder effect in oculocutaneous albinism type 7.

Clin Genet 2020 03 6;97(3):527-528. Epub 2019 Nov 6.

Reference Centre for Genodermatoses and Rare Skin Disease (MAGEC) and Department of Dermatology, Filière Maladies Rares Dermatologiques (FIMARAD), ERN-Skin Hôpital Necker-Enfants Malades, Université de Paris-Centre, Paris, France.

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http://dx.doi.org/10.1111/cge.13655DOI Listing
March 2020

Possible Paradoxical Photosensitive Psoriasis Induced by Tumour Necrosis Factor-alpha Inhibitors.

Acta Derm Venereol 2019 Dec;99(13):1293-1294

Department of Dermatology, Saint Louis hospital, FR-75012 Paris, France.

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http://dx.doi.org/10.2340/00015555-3330DOI Listing
December 2019
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