Publications by authors named "Paula Mera"

21Publications

Moderate SIRT1 overexpression protects against brown adipose tissue inflammation.

Authors:
Carmen Escalona-Garrido Patricia Vázquez Paula Mera Sebastián Zagmutt Ester García-Casarrubios Ana Montero-Pedrazuela Fernanda Rey-Stolle Ana Guadaño-Ferraz Francisco J Rupérez Dolors Serra Laura Herrero Maria Jesus Obregon Ángela M Valverde

Mol Metab 2020 Dec 10;42:101097. Epub 2020 Oct 10.

Instituto de Investigaciones Biomédicas Alberto Sols (Centro Mixto CSIC-UAM), 28029 Madrid, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERdem), 28029 Madrid, Spain. Electronic address:

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December 2020

Effects of High-Fat Diet and Maternal Binge-Like Alcohol Consumption and Their Influence on Cocaine Response in Female Mice Offspring.

Authors:
Leticia Duart-Castells Lídia Cantacorps Raúl López-Arnau Sandra Montagud-Romero Brigitte Puster Paula Mera Dolors Serra Jorge Camarasa David Pubill Olga Valverde Elena Escubedo

Int J Neuropsychopharmacol 2021 Jan;24(1):77-88

Department of Pharmacology, Toxicology and Therapeutic Chemistry, Pharmacology Section and Institute of Biomedicine (IBUB) Faculty of Pharmacy and Food Sciences, Universitat de Barcelona, Barcelona, Spain.

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January 2021

Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD.

Authors:
Minéia Weber Paula Mera Josefina Casas Javier Salvador Amaia Rodríguez Sergio Alonso David Sebastián M Carmen Soler-Vázquez Carla Montironi Sandra Recalde Raquel Fucho María Calderón-Domínguez Joan Francesc Mir Ramon Bartrons Joan Carles Escola-Gil David Sánchez-Infantes Antonio Zorzano Vicenta Llorente-Cortes Núria Casals Víctor Valentí Gema Frühbeck Laura Herrero Dolors Serra

FASEB J 2020 Sep 15;34(9):11816-11837. Epub 2020 Jul 15.

Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, Spain.

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September 2020

The role of epigenetics in the development of obesity.

Authors:
Arnaud Obri Dolors Serra Laura Herrero Paula Mera

Biochem Pharmacol 2020 07 10;177:113973. Epub 2020 Apr 10.

Regulation of Lipid Metabolism Laboratory, Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain. Electronic address:

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July 2020

Muscle-derived interleukin 6 increases exercise capacity by signaling in osteoblasts.

Authors:
Subrata Chowdhury Logan Schulz Biagio Palmisano Parminder Singh Julian M Berger Vijay K Yadav Paula Mera Helga Ellingsgaard Juan Hidalgo Jens Brüning Gerard Karsenty

J Clin Invest 2020 06;130(6):2888-2902

Department of Genetics and Development, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.

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June 2020

Impact of Adaptive Thermogenesis in Mice on the Treatment of Obesity.

Authors:
Marianela Bastías-Pérez Sebastián Zagmutt M Carmen Soler-Vázquez Dolors Serra Paula Mera Laura Herrero

Cells 2020 01 28;9(2). Epub 2020 Jan 28.

Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain.

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January 2020

New approaches targeting brown adipose tissue transplantation as a therapy in obesity.

Authors:
M Carmen Soler-Vázquez Paula Mera Sebastián Zagmutt Dolors Serra Laura Herrero

Biochem Pharmacol 2018 09 19;155:346-355. Epub 2018 Jul 19.

Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain. Electronic address:

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September 2018

Targeting AgRP neurons to maintain energy balance: Lessons from animal models.

Authors:
Sebastián Zagmutt Paula Mera M Carmen Soler-Vázquez Laura Herrero Dolors Serra

Biochem Pharmacol 2018 09 18;155:224-232. Epub 2018 Jul 18.

Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain. Electronic address:

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September 2018

Corrigendum to "Osteocalcin is necessary and sufficient to maintain muscle mass in older mice" [Mol Metabol 5 (2017) 1042-1047].

Authors:
Paula Mera Kathrin Laue Jianwen Wei Julian Meyer Berger Gerard Karsenty

Mol Metab 2017 08 22;6(8):941. Epub 2017 Jun 22.

Department of Genetics and Development, Columbia University Medical Center, New York, NY, 10032, USA. Electronic address:

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August 2017

Gpr158 mediates osteocalcin's regulation of cognition.

Authors:
Lori Khrimian Arnaud Obri Mariana Ramos-Brossier Audrey Rousseaud Stéphanie Moriceau Anne-Sophie Nicot Paula Mera Stylianos Kosmidis Theodoros Karnavas Frederic Saudou Xiao-Bing Gao Franck Oury Eric Kandel Gerard Karsenty

J Exp Med 2017 Oct 29;214(10):2859-2873. Epub 2017 Aug 29.

Department of Genetics and Development, Columbia University Medical Center, New York, NY

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October 2017

Regulation of Energy Metabolism by Bone-Derived Hormones.

Authors:
Paula Mera Mathieu Ferron Ioanna Mosialou

Cold Spring Harb Perspect Med 2018 06 1;8(6). Epub 2018 Jun 1.

Columbia University Medical Center, New York, New York 10032.

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June 2018

Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism.

Authors:
Yoshinori Matsumoto Jose La Rose Melissa Lim Hibret A Adissu Napoleon Law Xiaohong Mao Feng Cong Paula Mera Gerard Karsenty David Goltzman Adele Changoor Lucia Zhang Megan Stajkowski Marc D Grynpas Carsten Bergmann Robert Rottapel

J Clin Invest 2017 Jun 5;127(7):2612-2625. Epub 2017 Jun 5.

Princess Margaret Cancer Center, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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June 2017

Molecular bases of the crosstalk between bone and muscle.

Authors:
Gerard Karsenty Paula Mera

Bone 2018 10 18;115:43-49. Epub 2017 Apr 18.

Department of Genetics & Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address:

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October 2018

(-)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects.

Authors:
Kamil Makowski Joan Francesc Mir Paula Mera Xavier Ariza Guillermina Asins Fausto G Hegardt Laura Herrero Jordi García Dolors Serra

Eur J Med Chem 2017 May 12;131:207-221. Epub 2017 Mar 12.

Department of Biochemistry and Physiology, Facultat de Farmàcia i Ciències de l'A limentació and Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain; Institut de Biomedicina de la Universitat de Barcelona (IBUB), Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, E-28029 Madrid, Spain. Electronic address:

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May 2017

Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.

Authors:
Paula Mera Kathrin Laue Mathieu Ferron Cyril Confavreux Jianwen Wei Marta Galán-Díez Alain Lacampagne Sarah J Mitchell Julie A Mattison Yun Chen Justine Bacchetta Pawel Szulc Richard N Kitsis Rafael de Cabo Richard A Friedman Christopher Torsitano Timothy E McGraw Michelle Puchowicz Irwin Kurland Gerard Karsenty

Cell Metab 2017 01;25(1):218

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January 2017

Osteocalcin is necessary and sufficient to maintain muscle mass in older mice.

Authors:
Paula Mera Kathrin Laue Jianwen Wei Julian Meyer Berger Gerard Karsenty

Mol Metab 2016 Oct 16;5(10):1042-1047. Epub 2016 Jul 16.

Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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October 2016

Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.

Authors:
Paula Mera Kathrin Laue Mathieu Ferron Cyril Confavreux Jianwen Wei Marta Galán-Díez Alain Lacampagne Sarah J Mitchell Julie A Mattison Yun Chen Justine Bacchetta Pawel Szulc Richard N Kitsis Rafael de Cabo Richard A Friedman Christopher Torsitano Timothy E McGraw Michelle Puchowicz Irwin Kurland Gerard Karsenty

Cell Metab 2016 Jun;23(6):1078-1092

Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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June 2016

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile.

Authors:
Paula Mera Joan Francesc Mir Gemma Fabriàs Josefina Casas Ana S H Costa Maria Ida Malandrino José-Antonio Fernández-López Xavier Remesar Su Gao Shigeru Chohnan Maria Sol Rodríguez-Peña Harald Petry Guillermina Asins Fausto G Hegardt Laura Herrero Dolors Serra

PLoS One 2014 12;9(5):e97195. Epub 2014 May 12.

Department of Biochemistry and Molecular Biology, Facultat de Farmàcia, Universitat de Barcelona and Institut de Biomedicina de la Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Barcelona, Spain.

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June 2015

Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity.

Authors:
Kamil Makowski Paula Mera David Paredes Laura Herrero Xavier Ariza Guillermina Asins Fausto G Hegardt Jordi García Dolors Serra

Chirality 2013 May;25(5):281-7

Department of Biochemistry and Molecular Biology, Facultat de Farmàcia, Universitat de Barcelona, E-08028 Barcelona, Spain.

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May 2013

Mitochondrial fatty acid oxidation in obesity.

Authors:
Dolors Serra Paula Mera Maria Ida Malandrino Joan Francesc Mir Laura Herrero

Antioxid Redox Signal 2013 Jul 5;19(3):269-84. Epub 2012 Oct 5.

Department of Biochemistry and Molecular Biology, Facultat de Farmàcia, Universitat de Barcelona, Institut de Biomedicina de la Universitat de Barcelona IBUB, Barcelona, Spain.

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July 2013