Paula E Cohen

Paula E Cohen

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Paula E Cohen

Paula E Cohen

Publications by authors named "Paula E Cohen"

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Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis.

G3 (Bethesda) 2019 06 5;9(6):1839-1850. Epub 2019 Jun 5.

Department of Biomedical Sciences and Center for Reproductive Genomics, Cornell University, Ithaca, NY 14853

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http://dx.doi.org/10.1534/g3.119.400074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553527PMC
June 2019

NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.

PLoS One 2017 5;12(10):e0185780. Epub 2017 Oct 5.

Department of Biomedical Sciences and Center for Reproductive Genomics, Cornell University, Ithaca, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185780PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628868PMC
October 2017

Transcriptome profiling of the developing male germ line identifies the miR-29 family as a global regulator during meiosis.

RNA Biol 2017 02 16;14(2):219-235. Epub 2016 Dec 16.

a Department of Molecular Biology and Genetics , Cornell University , Ithaca , NY , USA.

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http://dx.doi.org/10.1080/15476286.2016.1270002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324742PMC
February 2017

Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation.

Annu Rev Genet 2016 Nov 14;50:175-210. Epub 2016 Sep 14.

Department of Biomedical Sciences and Center for Reproductive Genomics, Cornell University, Ithaca, New York 14853; email: ,

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http://dx.doi.org/10.1146/annurev-genet-120215-035111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319444PMC
November 2016

Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse.

Cell Rep 2016 10;17(4):977-986

Department of Biomedical Sciences and Center for Reproductive Genomics, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123770PMC
October 2016

The roles of microRNAs and siRNAs in mammalian spermatogenesis.

Development 2016 09;143(17):3061-73

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047671PMC
http://dx.doi.org/10.1242/dev.136721DOI Listing
September 2016

Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice.

Curr Biol 2016 Mar 18;26(5):678-85. Epub 2016 Feb 18.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus, Dr. Bohr-Gasse 3, Vienna 1030, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.12.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791431PMC
March 2016

Double trouble in human aneuploidy.

Nat Genet 2015 Jul;47(7):696-8

Department of Biomedical Sciences and the Center for Reproductive Genomics, Cornell University, Ithaca, New York, USA.

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http://dx.doi.org/10.1038/ng.3344DOI Listing
July 2015

Genetic recombination is targeted towards gene promoter regions in dogs.

PLoS Genet 2013 12;9(12):e1003984. Epub 2013 Dec 12.

Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861134PMC
August 2014

Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites.

J Cell Biol 2014 Jun 2;205(5):633-41. Epub 2014 Jun 2.

Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853

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http://dx.doi.org/10.1083/jcb.201401122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050721PMC
June 2014

Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination.

Nat Genet 2014 Feb 5;46(2):194-9. Epub 2014 Jan 5.

1] Howard Hughes Medical Institute, University of California, Davis, Davis, California, USA. [2] Department of Microbiology & Molecular Genetics, University of California, Davis, Davis, California, USA. [3] Department of Molecular & Cellular Biology, University of California, Davis, Davis, California, USA. [4] Department of Cell Biology & Human Anatomy, University of California, Davis, Davis, California, USA.

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http://dx.doi.org/10.1038/ng.2858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356240PMC
February 2014

Studying recombination in mouse oocytes.

Methods Mol Biol 2013 ;957:1-18

Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA.

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http://dx.doi.org/10.1007/978-1-62703-191-2_1DOI Listing
April 2013

SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors.

Genes Dev 2013 Apr;27(7):749-66

Howard Hughes Medical Institute, Department of Biochemistry, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1101/gad.210963.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639416PMC
April 2013

AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline.

Dev Cell 2012 Aug 2;23(2):251-64. Epub 2012 Aug 2.

Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1016/j.devcel.2012.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470808PMC
August 2012

Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis.

PLoS Genet 2011 Jun 2;7(6):e1002094. Epub 2011 Jun 2.

Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

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http://dx.plos.org/10.1371/journal.pgen.1002094
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http://dx.doi.org/10.1371/journal.pgen.1002094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107204PMC
June 2011

NEK1 Facilitates Cohesin Removal during Mammalian Spermatogenesis.

Genes (Basel) 2011 Mar;2(1):260-79

Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.3390/genes2010260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175124PMC
March 2011

Predicting gene networks in human oocyte meiosis.

Biol Reprod 2010 Mar 23;82(3):469-72. Epub 2009 Dec 23.

Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.

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http://dx.doi.org/10.1095/biolreprod.109.083014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366155PMC
March 2010

Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination.

J Cell Biol 2010 Mar;188(6):779-89

Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1083/jcb.200909048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845075PMC
March 2010

Analysis of meiotic prophase I in live mouse spermatocytes.

Chromosome Res 2008 2;16(5):743-60. Epub 2008 Jun 2.

Department of Biomedical Sciences and Center for Reproductive Genomics, Cornell University, College of Veterinary Medicine, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1007/s10577-008-1224-8DOI Listing
December 2008

Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.

Proc Natl Acad Sci U S A 2008 Oct 14;105(42):16248-53. Epub 2008 Oct 14.

Departments of Cell Biology and Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0808182105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571010PMC
October 2008

MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis.

PLoS Genet 2008 Sep 12;4(9):e1000186. Epub 2008 Sep 12.

Department of Biomedical Sciences, Cornell University, Ithaca, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525838PMC
September 2008

Distinct functions of MLH3 at recombination hot spots in the mouse.

Genetics 2008 Apr;178(4):1937-45

Department of Biomedical Sciences, Cornell University, Ithaca, New York 14850, USA.

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http://dx.doi.org/10.1534/genetics.107.084798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323788PMC
April 2008

Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway.

Biol Reprod 2008 Mar 5;78(3):462-71. Epub 2007 Dec 5.

Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY 14850, USA.

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http://dx.doi.org/10.1095/biolreprod.107.065771DOI Listing
March 2008

Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.

Proc Natl Acad Sci U S A 2008 Mar 12;105(11):4247-52. Epub 2008 Mar 12.

Department of Cell Biology and Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0800276105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2393764PMC
March 2008

Small RNAs and RNAi pathways in meiotic prophase I.

Chromosome Res 2007 ;15(5):653-65

Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1007/s10577-007-1144-zDOI Listing
October 2007

A role for Mlh3 in somatic hypermutation.

DNA Repair (Amst) 2006 Jun 27;5(6):675-82. Epub 2006 Mar 27.

Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461, USA.

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http://meiosis.cornell.edu/pubs/li2006.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S156878640600053
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http://dx.doi.org/10.1016/j.dnarep.2006.02.003DOI Listing
June 2006

Not all germ cells are created equal: aspects of sexual dimorphism in mammalian meiosis.

Reproduction 2005 Dec;130(6):761-81

Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1530/rep.1.00865DOI Listing
December 2005

Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression.

Development 2005 Mar 16;132(6):1463-73. Epub 2005 Feb 16.

Department of Biological Chemistry, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1242/dev.01658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898142PMC
March 2005

Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes.

Am J Hum Genet 2005 Jan 22;76(1):112-27. Epub 2004 Nov 22.

Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1086/427268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1196414PMC
January 2005

Mismatch repair proteins, meiosis, and mice: understanding the complexities of mammalian meiosis.

Exp Cell Res 2004 May;296(1):71-9

Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.yexcr.2004.03.020DOI Listing
May 2004

Meiotic arrest and aneuploidy in MLH3-deficient mice.

Nat Genet 2002 Aug 1;31(4):385-90. Epub 2002 Jul 1.

Division of Hematology-Oncology, Department of Medicine, University of California, Irvine, California 92697, USA.

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http://www.nature.com/articles/ng931
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http://dx.doi.org/10.1038/ng931DOI Listing
August 2002

Colony-stimulating factor 1 regulation of neuroendocrine pathways that control gonadal function in mice.

Endocrinology 2002 Apr;143(4):1413-22

Center for the Study of Reproductive Biology and Women's Health, Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/end
Publisher Site
http://dx.doi.org/10.1210/endo.143.4.8754DOI Listing
April 2002