Publications by authors named "Paul Walker"

100Publications

An Experimentally Defined Hypoxia Gene Signature in Glioblastoma and Its Modulation by Metformin.

Biology (Basel) 2020 Sep 2;9(9). Epub 2020 Sep 2.

Center for Translational Research in Onco-Hematology, Division of Oncology, Geneva University Hospitals and University of Geneva, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.3390/biology9090264DOI Listing
September 2020

Total Synthesis of Kalimantacin A.

Org Lett 2020 Aug 10;22(16):6349-6353. Epub 2020 Aug 10.

School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.

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http://dx.doi.org/10.1021/acs.orglett.0c02190DOI Listing
August 2020

Correction to: Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.

Arch Toxicol 2020 08;94(8):2731-2732

Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, AIMMS, Vrije Universiteit Amsterdam, De Boelelaan, 1108, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00204-020-02849-5DOI Listing
August 2020

Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.

Arch Toxicol 2020 08 18;94(8):2707-2729. Epub 2020 Jul 18.

Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, AIMMS, Vrije Universiteit Amsterdam, De Boelelaan, 1108, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00204-020-02792-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395062PMC
August 2020

Relative fitness and stability of resistance in a near-isogenic strain of indoxacarb resistant Helicoverpa armigera (Lepidoptera: Noctuidae).

Pest Manag Sci 2020 Jun 15. Epub 2020 Jun 15.

NSW Department of Primary Industries, Tamworth Agricultural Institute, Calala, New South Wales, Australia.

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http://dx.doi.org/10.1002/ps.5962DOI Listing
June 2020

Dialogic Consensus as the Moral Philosophical Basis for Shared Decision-making.

Authors:
Paul Walker

Linacre Q 2019 May 16;86(2-3):168-171. Epub 2019 May 16.

Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia.

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http://dx.doi.org/10.1177/0024363919841775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699040PMC
May 2019

The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development.

Arch Toxicol 2020 08 6;94(8):2559-2585. Epub 2020 May 6.

Cyprotex Discovery Ltd., No.24 Mereside, Alderley Park, Macclesfield, Cheshire, SK10 4TG, UK.

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http://dx.doi.org/10.1007/s00204-020-02763-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395068PMC
August 2020

Respiratory advice for the non-respiratory physician in the time of COVID-19.

Clin Med (Lond) 2020 May 4. Epub 2020 May 4.

Federation of Royal Colleges of Physicians of the UK, London, UK

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http://dx.doi.org/10.7861/clinmed.2020-0188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354050PMC
May 2020

Greyhound racing ideal trajectory path generation for straight to bend based on jerk rate minimization.

Sci Rep 2020 04 27;10(1):7088. Epub 2020 Apr 27.

Faculty of Engineering and Information Technology, University of Technology Sydney, Broadway, 2007, NSW, Australia.

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http://dx.doi.org/10.1038/s41598-020-63678-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184578PMC
April 2020

Is gender still a risk factor for mortality in patients who undergo elective repair of abdominal aortic aneurysms? A single centre experience.

J Cardiovasc Surg (Torino) 2020 Apr 1. Epub 2020 Apr 1.

Department of Vascular Surgery, James Cook University Hospital, Middlesbrough, UK -

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http://dx.doi.org/10.23736/S0021-9509.20.11196-0DOI Listing
April 2020

Development of a generic zebrafish embryo PBPK model and application to the developmental toxicity assessment of valproic acid analogs.

Reprod Toxicol 2020 04 28;93:219-229. Epub 2020 Feb 28.

CERTARA UK Limited, Simcyp Division, Level 2-Acero, 1 Concourse Way, Sheffield, S1 2BJ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2020.02.010DOI Listing
April 2020

Gastropharyngeal Anastomotic Leak in Medullary Thyroid Carcinoma Following Initiation of a Tyrosine Kinase Inhibitor: A Case Report of an Unusual Side Effect of Cabozantinib.

Ann Otol Rhinol Laryngol 2020 Jul 10;129(7):657-661. Epub 2020 Feb 10.

Department of Otolaryngology, Loma Linda University, Loma Linda, CA, USA.

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http://dx.doi.org/10.1177/0003489420902161DOI Listing
July 2020

A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis.

ACS Chem Biol 2020 02 6;15(2):494-503. Epub 2020 Feb 6.

School of Chemistry , University of Bristol , Cantock's Close , Bristol , BS8 1TS , United Kingdom.

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http://dx.doi.org/10.1021/acschembio.9b00969DOI Listing
February 2020

Impact of virtual simulation in self-care therapeutics course on introductory pharmacy practice experience self-care encounters.

Curr Pharm Teach Learn 2020 01 20;12(1):74-83. Epub 2019 Nov 20.

University of Michigan College of Pharmacy, 428 Church St, Suite 3563 NUB, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cptl.2019.10.015DOI Listing
January 2020

A Rare Case of Squamous Cell Carcinoma of the Esophagus in a Patient With Goltz Syndrome.

ACG Case Rep J 2019 Mar 8;6(3):1-4. Epub 2019 Mar 8.

Department of Internal Medicine, East Carolina University, Greenville, NC.

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http://dx.doi.org/10.14309/crj.0000000000000045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658022PMC
March 2019

Anaerobic Threshold (AT) is an independent predictor of medium term survival following elective endovascular repair of abdominal aortic aneurysm (EVAR).

J Cardiovasc Surg (Torino) 2019 Oct 4. Epub 2019 Oct 4.

Department of Vascular Surgery, James Cook University Hospital, Middlesbrough, UK -

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http://dx.doi.org/10.23736/S0021-9509.19.11052-XDOI Listing
October 2019

Control of β-Branching in Kalimantacin Biosynthesis: Application of C NMR to Polyketide Programming.

Angew Chem Int Ed Engl 2019 09 7;58(36):12446-12450. Epub 2019 Aug 7.

School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.

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http://doi.wiley.com/10.1002/anie.201905482
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http://dx.doi.org/10.1002/anie.201905482DOI Listing
September 2019

Isolated neutropenia as a rare but serious adverse event secondary to immune checkpoint inhibition.

J Immunother Cancer 2019 07 5;7(1):169. Epub 2019 Jul 5.

Division of Hematology/Oncology, East Carolina University, 600 Moye Boulevard, Greenville, NC, 27834, USA.

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http://dx.doi.org/10.1186/s40425-019-0648-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612131PMC
July 2019

The Use of Closure Devices for Aortic Stent-Graft Insertion: Outcomes Following a Paradigm Shift to Percutaneous Access in a Tertiary Vascular Center.

Vasc Endovascular Surg 2019 Oct 24;53(7):536-540. Epub 2019 Jun 24.

1 Department of Radiology, Leeds Teaching Hospital NHS Trust, Leeds General Infirmary, Leeds, West Yorkshire, UK.

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http://dx.doi.org/10.1177/1538574419858829DOI Listing
October 2019

Harnessing Microglia and Macrophages for the Treatment of Glioblastoma.

Front Pharmacol 2019 5;10:506. Epub 2019 Jun 5.

Département de Physique Nucléaire et Corpusculaire (DPNC), University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.3389/fphar.2019.00506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560150PMC
June 2019

Understanding the Awareness, Knowledge and Perceptions of Interventional Radiology Amongst Undergraduates in the UK.

Cardiovasc Intervent Radiol 2019 Oct 8;42(10):1459-1465. Epub 2019 May 8.

Leeds Teaching Hospitals NHS Trust, 10 Mansion Gate, Chapel Allerton, Leeds, LS7 4SX, UK.

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http://dx.doi.org/10.1007/s00270-019-02234-5DOI Listing
October 2019

Genetics, Chronic Obstructive Pulmonary Disease, and the Arrow of Time.

Am J Respir Crit Care Med 2019 Sep;200(6):654-655

Institute of Ageing and Chronic DiseaseUniversity of LiverpoolLiverpool, United Kingdomand.

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http://dx.doi.org/10.1164/rccm.201904-0813EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775883PMC
September 2019

High Content Screening in NHBE cells shows significantly reduced biological activity of flavoured e-liquids, when compared to cigarette smoke condensate.

Toxicol In Vitro 2019 Aug 14;58:86-96. Epub 2019 Mar 14.

Imperial Brands PLC, 121 Winterstoke Road, Bristol BS3 2LL, United Kingdom.

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http://dx.doi.org/10.1016/j.tiv.2019.03.018DOI Listing
August 2019

Mandibular reconstruction with the scapula tip free flap.

Head Neck 2019 07 14;41(7):2353-2358. Epub 2019 Mar 14.

Department of Otolaryngology - Head and Neck Surgery, University Health Network, Princess Margaret Cancer Center, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/hed.25702DOI Listing
July 2019

The Role of Endotoxin in Septic Shock-Reply.

JAMA 2019 03;321(9):903

Cooper University Hospital, Cooper Medical School of Rowan University, Camden, New Jersey.

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http://dx.doi.org/10.1001/jama.2018.20882DOI Listing
March 2019

Peptides as cancer vaccines.

Curr Opin Pharmacol 2019 08 1;47:20-26. Epub 2019 Mar 1.

Center for Translational Research in Onco-Hematology, Division of Oncology, Geneva University Hospitals and University of Geneva, Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2019.01.007DOI Listing
August 2019

Regarding "Long-Term Evaluation of Percutaneous Groin Access for EVAR".

Cardiovasc Intervent Radiol 2019 05 7;42(5):788. Epub 2019 Feb 7.

Department of Radiology, Leeds Teaching Hospital NHS Trust, Leeds, UK.

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http://dx.doi.org/10.1007/s00270-019-02174-0DOI Listing
May 2019

Aneurysm Morphology Is a More Significant Predictor of Survival than Hardman's Index in Patients with Ruptured or Acutely Symptomatic Abdominal Aortic Aneurysms.

Ann Vasc Surg 2019 Jul 24;58:222-231. Epub 2019 Jan 24.

Department of Vascular Surgery James Cook University Hospital, Middlesbrough, UK. Electronic address:

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http://dx.doi.org/10.1016/j.avsg.2018.10.018DOI Listing
July 2019

Dialogic Consensus in Medicine-A Justification Claim.

J Med Philos 2019 Jan;44(1):71-84

University of Newcastle, Callaghan, New South Wales, Australia.

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http://dx.doi.org/10.1093/jmp/jhy038DOI Listing
January 2019

Baseline Susceptibility of Helicoverpa punctigera (Lepidoptera: Noctuidae) to Indoxacarb, Emamectin Benzoate, and Chlorantraniliprole.

J Econ Entomol 2019 03;112(2):818-826

NSW Department of Primary Industries, Tamworth Agricultural Institute, Calala, Australia.

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http://dx.doi.org/10.1093/jee/toy389DOI Listing
March 2019

Grading trends and evaluation of student performance across advanced pharmacy practice experiences (APPE) in the Big Ten Academic Alliance (The GRAPPES study).

Curr Pharm Teach Learn 2018 11 3;10(11):1466-1473. Epub 2018 Sep 3.

The University of Michigan College of Pharmacy and Health System, 428 Church Street, Ann Arbor, MI 48109-1065, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cptl.2018.08.004DOI Listing
November 2018

Let there be oxygen and T cells.

Authors:
Paul R Walker

J Clin Invest 2018 11 15;128(11):4761-4763. Epub 2018 Oct 15.

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https://www.jci.org/articles/view/124305
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http://dx.doi.org/10.1172/JCI124305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205379PMC
November 2018

Screening Heroin Smokers Attending Community Drug Services for COPD.

Chest 2019 02 4;155(2):279-287. Epub 2018 Sep 4.

University Hospital Aintree, Liverpool, England. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2018.08.1049DOI Listing
February 2019

Use of zonal distribution of lung crackles during inspiration and expiration to assess disease severity in idiopathic pulmonary fibrosis.

Postgrad Med J 2018 Jul 12;94(1113):381-385. Epub 2018 Jun 12.

Department of Respiratory Medicine, University Hospital Aintree, Liverpool, UK.

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http://dx.doi.org/10.1136/postgradmedj-2017-135320DOI Listing
July 2018

Stage III non-small cell lung cancer: escalation matters, but how?

Transl Lung Cancer Res 2018 Apr;7(Suppl 2):S107-S110

Brody School of Medicine at East Carolina University, Greenville, NC, USA.

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http://dx.doi.org/10.21037/tlcr.2018.03.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943225PMC
April 2018

Automatic deformable PET/MRI registration for preclinical studies based on B-splines and non-linear intensity transformation.

Med Biol Eng Comput 2018 Sep 7;56(9):1531-1539. Epub 2018 Feb 7.

Le2i FRE2005, CNRS, Arts et Métiers, Université Bourgogne Franche-Comté, Dijon, France.

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http://dx.doi.org/10.1007/s11517-018-1797-0DOI Listing
September 2018

The survival benefit of neoadjuvant chemotherapy and pCR among patients with advanced stage triple negative breast cancer.

Oncotarget 2017 Dec 20;8(68):112712-112719. Epub 2017 Nov 20.

Division of Hematology/Oncology, Vidant Health Cancer Care, Greenville, NC, USA.

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http://dx.doi.org/10.18632/oncotarget.22521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762543PMC
December 2017

Antigenic expression and spontaneous immune responses support the use of a selected peptide set from the IMA950 glioblastoma vaccine for immunotherapy of grade II and III glioma.

Oncoimmunology 2018 7;7(2):e1391972. Epub 2017 Nov 7.

Department of Oncology, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1204 Geneva 11, Switzerland and Department of Internal Medicine Specialties, Faculty of Medicine, University of Geneva, Rue Michel-Servet 1, 1205 Geneva Switzerland.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2017.1
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http://dx.doi.org/10.1080/2162402X.2017.1391972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749651PMC
November 2017

Microvascular replantation of a composite facial avulsion in a 24-month-old child after dog bite.

Microsurgery 2018 Feb 12;38(2):218-221. Epub 2017 Dec 12.

Loma Linda University Department of Otolaryngology, Head and Neck Surgery, Loma Linda, California.

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http://dx.doi.org/10.1002/micr.30275DOI Listing
February 2018

Tocilizumab for the management of immune mediated adverse events secondary to PD-1 blockade.

J Oncol Pharm Pract 2019 Apr 5;25(3):551-557. Epub 2017 Dec 5.

Department of Hematology Oncology, Leo Jenkins Cancer Center at East Carolina University, Greenville, USA.

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http://dx.doi.org/10.1177/1078155217745144DOI Listing
April 2019

Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches.

Regul Toxicol Pharmacol 2018 Mar 25;93:62-70. Epub 2017 Oct 25.

British American Tobacco, Research and Development Centre, Southampton, Hampshire, SO15 8TL, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S02732300173026
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http://dx.doi.org/10.1016/j.yrtph.2017.08.016DOI Listing
March 2018

Local Radiotherapy Intensification for Locally Advanced Non-small-cell Lung Cancer - A Call to Arms.

Clin Lung Cancer 2018 01 16;19(1):17-26. Epub 2017 Jun 16.

Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC.

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http://dx.doi.org/10.1016/j.cllc.2017.05.024DOI Listing
January 2018

Metastatic melanoma in a 95 years old patient responding to treatment with talimogene laherparepvec followed by nivolumab.

Acta Oncol 2017 10 8;56(10):1327-1330. Epub 2017 May 8.

a Division of Hematology/Oncology , East Carolina University , Greenville , NC , USA.

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http://dx.doi.org/10.1080/0284186X.2017.1324212DOI Listing
October 2017

CREBH Maintains Circadian Glucose Homeostasis by Regulating Hepatic Glycogenolysis and Gluconeogenesis.

Mol Cell Biol 2017 07 29;37(14). Epub 2017 Jun 29.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan, USA

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http://dx.doi.org/10.1128/MCB.00048-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492176PMC
July 2017

Has the autonomy pendulum swung too far?

Authors:
Paul Walker

ANZ J Surg 2018 Jun 25;88(6):536-539. Epub 2017 Apr 25.

Faculty of Health and Medicine, The University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1111/ans.14053DOI Listing
June 2018

Local Intraluminal Irrigation With Argatroban During Free Flap Repair in a Patient With Heparin-Induced Thrombocytopenia.

Ann Otol Rhinol Laryngol 2017 May 1;126(5):407-410. Epub 2017 Mar 1.

2 Loma Linda University Medical Center, Department of Otolaryngology, Head & Neck Surgery & Facial Plastic Surgery, Loma Linda, California, USA.

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http://journals.sagepub.com/doi/10.1177/0003489417693015
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http://dx.doi.org/10.1177/0003489417693015DOI Listing
May 2017

F-Choline Positron Emission Tomography/Computed Tomography and Multiparametric Magnetic Resonance Imaging for the Detection of Early Local Recurrence of Prostate Cancer Initially Treated by Radiation Therapy: Comparison With Systematic 3-Dimensional Transperineal Mapping Biopsy.

Int J Radiat Oncol Biol Phys 2017 04 28;97(5):986-994. Epub 2016 Dec 28.

Department of Nuclear Medicine, Centre Georges-François Leclerc, Dijon, France; LE2I UMR6306, Centre national de la recherche scientifique, Arts et Métiers, Université Bourgogne Franche-Comté, Dijon, France; MRI Unit, Centre Hospitalier Régional Universitaire, Hôpital François Mitterrand, Dijon, France.

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http://dx.doi.org/10.1016/j.ijrobp.2016.12.025DOI Listing
April 2017

[Brain tumor immunotherapy: Illusion or hope?]

Bull Cancer 2017 May 17;104(5):476-484. Epub 2017 Mar 17.

Hôpitaux universitaires de Genève, centre d'oncologie, 4, rue Gabrielle-Perret-Gentil, 1211 Genève, Suisse. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2017.01.014DOI Listing
May 2017

Hypoxia and antitumor CD8 T cells: An incompatible alliance?

Oncoimmunology 2016 9;5(12):e1232236. Epub 2016 Sep 9.

Geneva University Hospitals and University of Geneva , Geneva, Switzerland.

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http://dx.doi.org/10.1080/2162402X.2016.1232236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214994PMC
September 2016

Socioeconomic deprivation and the outcome of pulmonary rehabilitation in England and Wales.

Thorax 2017 06 11;72(6):530-537. Epub 2017 Jan 11.

Leicester Respiratory Biomedical Research Unit, Institute for Lung Health, University Hospitals of Leicester NHS Trust, Leicester, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2016-209376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520271PMC
June 2017

Primary squamous cell carcinoma of the prostate: a case report of a rare clinical entity.

Future Sci OA 2015 Nov 1;1(3):FSO18. Epub 2015 Nov 1.

Leo Jenkins Cancer Center, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA; Leo Jenkins Cancer Center, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.

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http://dx.doi.org/10.4155/fso.15.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138001PMC
November 2015

Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?

Front Oncol 2016 7;6:256. Epub 2016 Dec 7.

Laboratory of Tumor Immunology, Center of Oncology, Geneva University Hospitals and University of Geneva , Geneva , Switzerland.

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http://dx.doi.org/10.3389/fonc.2016.00256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141244PMC
December 2016

Validation of a Decision Tree to Streamline Infrainguinal Vein Graft Surveillance.

Ann Vasc Surg 2017 Apr 24;40:216-222. Epub 2016 Nov 24.

Department of Interventional Radiology, The James Cook University Hospital, Middlesbrough, UK.

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http://dx.doi.org/10.1016/j.avsg.2016.07.082DOI Listing
April 2017

What are normal relaxation times of tissues at 3 T?

Magn Reson Imaging 2017 Jan 2;35:69-80. Epub 2016 Sep 2.

Le2i UMR6306, CNRS, Arts et Métiers, Univ. Bourgogne Franche-Comté. Dijon, France. Electronic address:

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http://dx.doi.org/10.1016/j.mri.2016.08.021DOI Listing
January 2017

Dialogic Consensus In Clinical Decision-Making.

J Bioeth Inq 2016 Dec 17;13(4):571-580. Epub 2016 Aug 17.

Philosophy, Religion & Theology, University of Newcastle, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1007/s11673-016-9743-zDOI Listing
December 2016