Paul W Harms

Paul W Harms

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Paul W Harms

Paul W Harms

Publications by authors named "Paul W Harms"

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A Case of Adjacent, Clonally Distinct Borderline Melanocytic Tumors on the Arm.

Am J Dermatopathol 2020 Jan;42(1):e7-e10

Dermatology, University of Michigan Medical School, Ann Arbor, MI.

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http://dx.doi.org/10.1097/DAD.0000000000001472DOI Listing
January 2020

A pediatric case of pigmented epithelioid melanocytoma with chromosomal copy number alterations in 15q and 17q and a novel NTRK3-SCAPER gene fusion.

J Cutan Pathol 2020 Jan 11;47(1):70-75. Epub 2019 Sep 11.

Department of Urology, Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan.

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http://dx.doi.org/10.1111/cup.13566DOI Listing
January 2020

Danger is only skin deep: aggressive epidermal carcinomas. An overview of the diagnosis, demographics, molecular-genetics, staging, prognostic biomarkers, and therapeutic advances in Merkel cell carcinoma.

Mod Pathol 2020 Jan 1;33(Suppl 1):42-55. Epub 2019 Nov 1.

Department of Pathology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41379-019-0394-6DOI Listing
January 2020

Expanding the differential of superficial tumors with round-cell morphology: Report of three cases of CIC-rearranged sarcoma, a potentially under-recognized entity.

J Cutan Pathol 2019 Dec 30. Epub 2019 Dec 30.

Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center and Geisel School of Medicine at Dartmouth, One Medical Center Drive, New Hampshire, Lebanon.

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http://dx.doi.org/10.1111/cup.13639DOI Listing
December 2019

Altered Rb, p16, and p53 expression is specific for porocarcinoma relative to poroma.

J Cutan Pathol 2019 Sep 3;46(9):659-664. Epub 2019 May 3.

Department of Pathology, Michigan Medicine, Ann Arbor, Michigan.

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http://dx.doi.org/10.1111/cup.13480DOI Listing
September 2019

Utility of CD123 immunohistochemistry in differentiating lupus erythematosus from cutaneous T cell lymphoma.

Histopathology 2019 May 20;74(6):908-916. Epub 2019 Mar 20.

Department of Pathology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1111/his.13817DOI Listing
May 2019

Molecular testing of borderline cutaneous melanocytic lesions: SNP array is more sensitive and specific than FISH.

Hum Pathol 2019 04 18;86:115-123. Epub 2018 Dec 18.

Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA 48109-5602; Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA 48109-5602. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.12.002DOI Listing
April 2019

Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma.

Neoplasia 2019 03 21;21(3):322-330. Epub 2019 Feb 21.

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA; Department of Urology, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384317PMC
March 2019

Neurofilament is superior to cytokeratin 20 in supporting cutaneous origin for neuroendocrine carcinoma.

Histopathology 2019 Feb 5;74(3):504-513. Epub 2018 Dec 5.

Department of Pathology, Michigan Medicine/University of Michigan Health System, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1111/his.13758DOI Listing
February 2019

Completion Lymph Node Dissection or Radiation Therapy for Sentinel Node Metastasis in Merkel Cell Carcinoma.

Ann Surg Oncol 2019 Feb 17;26(2):386-394. Epub 2018 Dec 17.

Division of Surgical Oncology, Department of Surgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109-5932, USA.

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http://link.springer.com/10.1245/s10434-018-7072-7
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http://dx.doi.org/10.1245/s10434-018-7072-7DOI Listing
February 2019

The biology and treatment of Merkel cell carcinoma: current understanding and research priorities.

Nat Rev Clin Oncol 2018 12;15(12):763-776

Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and National Cancer Institute (NCI), NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41571-018-0103-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319370PMC
December 2018

Subungual atypical lentiginous melanocytic proliferations in children and adolescents: A clinicopathologic study.

J Am Acad Dermatol 2018 Aug 27;79(2):327-336.e2. Epub 2018 Mar 27.

Department of Pathology, University of Michigan, Ann Arbor, Michigan; Department of Dermatology, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2018.03.030DOI Listing
August 2018

Malignant melanoma with osteosarcomatous differentiation in a lymph node metastasis.

J Cutan Pathol 2018 May 20. Epub 2018 May 20.

Department of Pathology, University of Michigan, Ann Arbor, Michigan.

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http://doi.wiley.com/10.1111/cup.13283
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http://dx.doi.org/10.1111/cup.13283DOI Listing
May 2018

Psammomatous Squamous Cell Carcinoma of the Skin.

Am J Dermatopathol 2018 Mar;40(3):e38-e40

Departments of Pathology, and.

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http://dx.doi.org/10.1097/DAD.0000000000001001DOI Listing
March 2018

Metastatic Merkel cell carcinoma response to nivolumab.

J Immunother Cancer 2016 15;4:79. Epub 2016 Nov 15.

Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, C451 Med Inn, 1500 East Medical Center Drive, Ann Arbor, MI 48109 USA.

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http://dx.doi.org/10.1186/s40425-016-0186-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109712PMC
February 2018

Comprehensive histopathological comparison of epidermotropic/dermal metastatic melanoma and primary nodular melanoma.

Histopathology 2018 Feb 21;72(3):472-480. Epub 2017 Nov 21.

Department of Pathology, University of Michigan, Ann Arbor, MI, USA.

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http://doi.wiley.com/10.1111/his.13384
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http://dx.doi.org/10.1111/his.13384DOI Listing
February 2018

Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.

Cancer Cell 2018 02 27;33(2):229-243.e4. Epub 2018 Jan 27.

Departments of Dermatology, and Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811398PMC
February 2018

Solitary Fibrous Tumors of the Head and Neck: A Multi-Institutional Clinicopathologic Study.

Am J Surg Pathol 2017 Dec;41(12):1642-1656

*Departments of Pathology and Surgery, VCU School of Medicine, Richmond, VA †Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA §Biostatistics Facility, University of Pittsburgh Cancer Institute **Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA ∥Department of Pathology, SUNY Upstate Medical University, Syracuse, NY Departments of ‡Pathology ¶Dermatology ††Oral and Maxillofacial Surgery, University of Michigan Health System, Ann Arbor #Department of Urology, Henry Ford Health System, Detroit, MI.

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http://dx.doi.org/10.1097/PAS.0000000000000940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680135PMC
December 2017

Gynecologic melanomas: A clinicopathologic and molecular analysis.

Gynecol Oncol 2017 11 24;147(2):351-357. Epub 2017 Aug 24.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, United States; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2017.08.023DOI Listing
November 2017

Histologic Mimics of Basal Cell Carcinoma.

Arch Pathol Lab Med 2017 Nov;141(11):1490-1502

From the Departments of Pathology (Drs Stanoszek, Wang, and Harms) and Dermatology (Dr Harms), University of Michigan Medical School, Ann Arbor. Drs Stanoszek and Wang contributed equally.

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http://dx.doi.org/10.5858/arpa.2017-0222-RADOI Listing
November 2017

Increased expression of EZH2 in Merkel cell carcinoma is associated with disease progression and poorer prognosis.

Hum Pathol 2017 09 21;67:78-84. Epub 2017 Jul 21.

Department of Dermatology, University of Michigan Health System, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2017.07.009DOI Listing
September 2017

Update on Merkel Cell Carcinoma.

Authors:
Paul W Harms

Clin Lab Med 2017 09 13;37(3):485-501. Epub 2017 Jun 13.

Department of Pathology, University of Michigan Medical School, 3261 Medical Science I, 1301 Catherine Street, Ann Arbor, MI 48109-5602, USA; Department of Dermatology, University of Michigan Medical School, 3261 Medical Science I, 1301 Catherine Street, Ann Arbor, MI 48109-5602, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02722712173004
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http://dx.doi.org/10.1016/j.cll.2017.05.004DOI Listing
September 2017

IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis.

J Allergy Clin Immunol 2017 Jul 31;140(1):109-120. Epub 2016 Dec 31.

Department of Dermatology, University of Michigan, Ann Arbor, Mich.

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http://dx.doi.org/10.1016/j.jaci.2016.08.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494022PMC
July 2017

Molecular Profiling of Multiple Primary Merkel Cell Carcinoma to Distinguish Genetically Distinct Tumors From Clonally Related Metastases.

JAMA Dermatol 2017 06;153(6):505-512

Department of Dermatology, University of Michigan Medical School, Ann Arbor3Michigan Center for Translational Pathology, University of Michigan, Ann Arbor4Department of Pathology, University of Michigan Medical School, Ann Arbor.

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http://dx.doi.org/10.1001/jamadermatol.2017.0507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540059PMC
June 2017

Erratum to: Metastatic Merkel cell carcinoma response to nivolumab.

J Immunother Cancer 2017 6;5:27. Epub 2017 Mar 6.

Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, C451 Med Inn, 1500 East Medical Center Drive, Ann Arbor, MI 48109 USA.

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http://dx.doi.org/10.1186/s40425-017-0221-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340072PMC
March 2017

Loss of p16 expression and copy number changes of CDKN2A in a spectrum of spitzoid melanocytic lesions.

Hum Pathol 2016 12 26;58:152-160. Epub 2016 Aug 26.

Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109; Department of Dermatology, University of Michigan Health System, Ann Arbor, MI 48109.

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http://dx.doi.org/10.1016/j.humpath.2016.07.029DOI Listing
December 2016

In Reply.

Arch Pathol Lab Med 2016 12;140(12):1317

1   Department of Dermatology, University of Michigan Health Systems, Ann Arbor.

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http://dx.doi.org/10.5858/arpa.2016-0306-LEDOI Listing
December 2016

Detection of Occult Invasion in Melanoma In Situ.

JAMA Dermatol 2016 11;152(11):1201-1208

Department of Dermatology, University of Michigan Medical School and Comprehensive Cancer Center, Ann Arbor4Department of Pathology, University of Michigan Medical School and Comprehensive Cancer Center, Ann Arbor.

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http://dx.doi.org/10.1001/jamadermatol.2016.2668DOI Listing
November 2016

Morpheaform Basal Cell Carcinomas With Areas of Predominantly Single-Cell Pattern of Infiltration: Diagnostic Utility of p63 and Cytokeratin.

Am J Dermatopathol 2016 Oct;38(10):744-50

Departments of *Pathology and †Dermatology, University of Michigan Health System, Ann Arbor MI; ‡Michigan Center for Translational Pathology, University of Michigan Health System, Ann Arbor MI; and §Department of Urology, Vattikutti Urology Institute, Henry Ford Health System, Detroit, MI.

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http://dx.doi.org/10.1097/DAD.0000000000000541DOI Listing
October 2016

Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?

J Invest Dermatol 2016 09 14;136(9):1792-1800. Epub 2016 Jun 14.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor Veterans Affairs Hospital, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.05.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112032PMC
September 2016

Immunohistochemical evaluation of p16 expression in cutaneous histiocytic, fibrohistiocytic and undifferentiated lesions.

J Cutan Pathol 2016 Aug 6;43(8):671-8. Epub 2016 Jun 6.

Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1111/cup.12730DOI Listing
August 2016

Translational significance of Nodal, Cripto-1 and Notch4 in adult nevi.

Oncol Lett 2016 Aug 21;12(2):1349-1354. Epub 2016 Jun 21.

Cancer Biology and Epigenomics Program, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.3892/ol.2016.4755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950573PMC
August 2016

Porocarcinomas harbor recurrent HRAS-activating mutations and tumor suppressor inactivating mutations.

Hum Pathol 2016 May 7;51:25-31. Epub 2016 Jan 7.

Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109; Michigan Center for Translational Pathology, University of Michigan Health System, Ann Arbor, MI 48109; Department of Urology, University of Michigan Health System, Ann Arbor, MI 48109; Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, MI 48109. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2015.12.015DOI Listing
May 2016

Atypical Spitz Tumors: A Diagnostic Challenge.

Arch Pathol Lab Med 2015 Oct;139(10):1263-70

From the Department of Dermatology (Drs K. L. Harms, Lowe, Fullen, and P. W. Harms), the Comprehensive Cancer Center (Dr K. L. Harms), and the Department of Dermatology and Pathology (Drs Lowe, Fullen, and P. W. Harms), University of Michigan Medical School, Ann Arbor.

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http://dx.doi.org/10.5858/arpa.2015-0207-RADOI Listing
October 2015

Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses.

Hum Pathol 2015 May 14;46(5):690-7. Epub 2015 Jan 14.

Department of Pathology, University of Michigan Health System, Ann Arbor MI 48109; Department of Dermatology, University of Michigan Health System, Ann Arbor MI 48109.

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http://dx.doi.org/10.1016/j.humpath.2015.01.006DOI Listing
May 2015

Cytokeratin 20-negative Merkel cell carcinoma is infrequently associated with the Merkel cell polyomavirus.

Mod Pathol 2015 Apr 14;28(4):498-504. Epub 2014 Nov 14.

Department of Pathology, The Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1038/modpathol.2014.148DOI Listing
April 2015

Small cell carcinoma in the parotid harboring Merkel cell polyomavirus.

Oral Surg Oral Med Oral Pathol Oral Radiol 2014 Dec 17;118(6):703-12. Epub 2014 Sep 17.

School of Dentistry, University of Michigan, Ann Arbor, MI. Electronic address:

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http://dx.doi.org/10.1016/j.oooo.2014.09.012DOI Listing
December 2014

Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes.

Nat Commun 2014 Dec 22;5:5893. Epub 2014 Dec 22.

1] Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [2] Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [3] Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [4] Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/ncomms6893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274748PMC
December 2014

Clear cell melanoma: a cutaneous clear cell malignancy.

Arch Pathol Lab Med 2014 Oct;138(10):1328-36

From the Departments of Pathology (Drs Pletneva, Andea, Palanisamy, Betz, Wang, Patel, Fullen, and Harms, and Ms Carskadon) and Dermatology (Drs Andea Patel, Fullen, and Harms), and the Michigan Center for Translational Pathology (Drs Palanisamy and Harms, and Ms Carskadon), University of Michigan Medical Center, Ann Arbor.

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http://dx.doi.org/10.5858/arpa.2014-0307-CCDOI Listing
October 2014

Merkel cell carcinoma dependence on bcl-2 family members for survival.

J Invest Dermatol 2014 Aug 10;134(8):2241-2250. Epub 2014 Mar 10.

Department of Dermatology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA; Department of Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181590PMC
August 2014

Mycosis fungoides with CD20 expression: report of two cases and review of the literature.

J Cutan Pathol 2014 Jun 26;41(6):494-503. Epub 2014 Feb 26.

Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1111/cup.12299DOI Listing
June 2014

Rosette-like structures in the spectrum of spitzoid tumors.

J Cutan Pathol 2013 Sep 29;40(9):788-95. Epub 2013 Jun 29.

Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1111/cup.12192DOI Listing
September 2013

Mandibular Actinomyces osteomyelitis complicating florid cemento-osseous dysplasia: case report.

BMC Oral Health 2011 Jul 21;11:21. Epub 2011 Jul 21.

Department of Oral and Maxillofacial Surgery, University of Michigan Medical School, 1150 W. Medical Center Drive, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1186/1472-6831-11-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151221PMC
July 2011

CD163 expression in leukemia cutis.

J Cutan Pathol 2010 Sep 18;37(9):953-7. Epub 2010 Feb 18.

Department of Pathology, University of Michigan Medical Center, Ann Arbor, MI 48109-0602, USA.

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http://dx.doi.org/10.1111/j.1600-0560.2010.01533.xDOI Listing
September 2010

Expression of the embryonic morphogen Nodal in cutaneous melanocytic lesions.

Mod Pathol 2010 Sep 21;23(9):1209-14. Epub 2010 May 21.

Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109-0602, USA.

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http://dx.doi.org/10.1038/modpathol.2010.101DOI Listing
September 2010

Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto.

Genes Dev 2003 Nov 16;17(21):2624-9. Epub 2003 Oct 16.

Department of Cell Biology, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1101/gad.1127703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC280611PMC
November 2003