Paul T Edlefsen

Paul T Edlefsen

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Paul T Edlefsen

Paul T Edlefsen

Publications by authors named "Paul T Edlefsen"

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32Publications

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Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features.

PLoS Comput Biol 2019 04 1;15(4):e1006952. Epub 2019 Apr 1.

Vaccine and Infectious Disease Division and Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459550PMC
April 2019

HIV population-level adaptation can rapidly diminish the impact of a partially effective vaccine.

Vaccine 2018 01 11;36(4):514-520. Epub 2017 Dec 11.

Center for Studies in Demography and Ecology, University of Washington, Seattle, WA, USA; Department of Anthropology, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.vaccine.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701864PMC
January 2018

Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.

AIDS Res Hum Retroviruses 2016 Oct/Nov;32(10-11):1031-1045. Epub 2016 Jul 26.

1 Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health , Boston, Massachusetts.

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http://dx.doi.org/10.1089/AID.2015.0330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067802PMC
December 2017

No Evidence of Pritelivir Resistance Among Herpes Simplex Virus Type 2 Isolates After 4 Weeks of Daily Therapy.

J Infect Dis 2016 07 7;214(2):258-64. Epub 2016 Apr 7.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center Department of Laboratory Medicine Department of Medicine, University of Washington, Seattle.

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http://dx.doi.org/10.1093/infdis/jiw129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918824PMC
July 2016

Use of placebos in Phase 1 preventive HIV vaccine clinical trials.

Vaccine 2015 Feb 23;33(6):749-52. Epub 2014 Oct 23.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Biostatistics, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.vaccine.2014.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554766PMC
February 2015

Leaky vaccines protect highly exposed recipients at a lower rate: implications for vaccine efficacy estimation and sieve analysis.

Authors:
Paul T Edlefsen

Comput Math Methods Med 2014 7;2014:813789. Epub 2014 May 7.

Fred Hutchinson Cancer Research Center, Seattle, WA 91809, USA.

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http://dx.doi.org/10.1155/2014/813789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033482PMC
December 2014

Low Multiplicity of HIV-1 Infection and No Vaccine Enhancement in VAX003 Injection Drug Users.

Open Forum Infect Dis 2014 Sep 14;1(2):ofu056. Epub 2014 Aug 14.

Perelman School of Medicine , University of Pennsylvania , Philadelphia.

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http://dx.doi.org/10.1093/ofid/ofu056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281816PMC
September 2014

Sieve analysis in HIV-1 vaccine efficacy trials.

Curr Opin HIV AIDS 2013 Sep;8(5):432-6

Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1097/COH.0b013e328362db2bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863593PMC
September 2013

Transposon identification using profile HMMs.

BMC Genomics 2010 Feb 10;11 Suppl 1:S10. Epub 2010 Feb 10.

Department of Statistics, Harvard University, Cambridge, MA, USA.

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http://dx.doi.org/10.1186/1471-2164-11-S1-S10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822524PMC
February 2010