Publications by authors named "Paul Skehel"

31Publications

Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity.

Cell Rep 2019 Dec;29(11):3620-3635.e7

Centre for Discovery Brain Sciences and Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, UK; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH8 9XD, UK. Electronic address:

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December 2019

The human NMDA receptor GluN2A variant influences channel blocker potency.

Pharmacol Res Perspect 2019 08 20;7(4):e00495. Epub 2019 Jun 20.

Centre for Discovery Brain Sciences Hugh Robson Building, University of Edinburgh Edinburgh UK.

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August 2019

Regional Molecular Mapping of Primate Synapses during Normal Healthy Aging.

Cell Rep 2019 04;27(4):1018-1026.e4

The Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, Edinburgh EH25 9RG, UK; Euan MacDonald Centre, Chancellor's Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK; Centre for Dementia Prevention, University of Edinburgh, 9A Bioquarter, 9 Little France Road, Edinburgh EH16 4UX, UK. Electronic address:

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April 2019

Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy.

J Physiol 2019 03 30;597(6):1691-1704. Epub 2019 Jan 30.

Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh, UK.

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March 2019

Auto-inhibition of adenylyl cyclase 9 (AC9) by an isoform-specific motif in the carboxyl-terminal region.

Cell Signal 2018 11 16;51:266-275. Epub 2018 Aug 16.

Division of Preclinical Research, Egis Pharmaceuticals PLC, Budapest, Hungary; Centre for Discovery Brain Sciences, Deanery of Biomedical Sciences University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

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November 2018

Initial characterisation of adult human ovarian cell populations isolated by DDX4 expression and aldehyde dehydrogenase activity.

Sci Rep 2018 05 3;8(1):6953. Epub 2018 May 3.

Institute of Cell Biology and the Centre for Integrative Physiology, Hugh Robson Building, University of Edinburgh, Edinburgh, EH8 9XD, UK.

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May 2018

A Bi-fluorescence complementation system to detect associations between the Endoplasmic reticulum and mitochondria.

Sci Rep 2017 12 12;7(1):17467. Epub 2017 Dec 12.

Centre for Integrative Physiology, Euan MacDonald Centre for Motor Neurone Disease Research, The University of Edinburgh, Edinburgh EH8 9XD, UK.

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December 2017

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture.

Mol Neurodegener 2017 10 27;12(1):77. Epub 2017 Oct 27.

Division of Neurobiology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.

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October 2017

Functional assessment of the NMDA receptor variant GluN2A .

Wellcome Open Res 2017 Mar 17;2:20. Epub 2017 Mar 17.

Centre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, UK.

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March 2017

De novo point mutations in patients diagnosed with ataxic cerebral palsy.

Brain 2015 Jul 16;138(Pt 7):1817-32. Epub 2015 May 16.

4 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK 16 Department of Clinical Genetics, Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford, OX3 7LJ, UK

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July 2015

Endomicroscopy and electromyography of neuromuscular junctions in situ.

Ann Clin Transl Neurol 2014 Nov 10;1(11):867-83. Epub 2014 Oct 10.

Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh Hugh Robson Building, George Square, Edinburgh, EH8 9XD, United Kingdom.

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November 2014

β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations.

Hum Mol Genet 2014 Jul 6;23(14):3875-82. Epub 2014 Mar 6.

The Centre for Integrative Physiology and Euan MacDonald Centre for Motor Neuron Disease Research, The University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, UK and

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July 2014

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.

J Neurochem 2013 Jan 15;124(1):26-35. Epub 2012 Nov 15.

Centre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.

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January 2013