Paul S Meltzer

Paul S Meltzer

UNVERIFIED PROFILE

Are you Paul S Meltzer?   Register this Author

Register author
Paul S Meltzer

Paul S Meltzer

Publications by authors named "Paul S Meltzer"

Are you Paul S Meltzer?   Register this Author

100Publications

3342Reads

33Profile Views

RNA Sequencing of the NCI-60: Integration into CellMiner and CellMiner CDB.

Cancer Res 2019 Jul 21;79(13):3514-3524. Epub 2019 May 21.

Developmental Therapeutic Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-18-2047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615556PMC
July 2019

Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background.

Blood 2019 Jun 16;133(24):2610-2614. Epub 2019 Apr 16.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood.2018864173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566592PMC
June 2019

Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells.

Sci Rep 2019 Mar 14;9(1):4544. Epub 2019 Mar 14.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-019-41058-8
Publisher Site
http://dx.doi.org/10.1038/s41598-019-41058-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418139PMC
March 2019

CDC73 Germline Mutation in a Family With Mixed Epithelial and Stromal Tumors.

Urology 2019 02 16;124:91-97. Epub 2018 Nov 16.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00904295183120
Publisher Site
http://dx.doi.org/10.1016/j.urology.2018.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382532PMC
February 2019

Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis.

Clin Cancer Res 2018 Oct 2;24(20):4997-5011. Epub 2018 Jul 2.

Institute of Pathology, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-18-0630DOI Listing
October 2018

Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133 Skin Cancer Stem Cells.

Mol Cancer Ther 2018 09 29;17(9):2034-2048. Epub 2018 Jun 29.

Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, NIH, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-17-0421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461743PMC
September 2018

A Non-canonical Polycomb Dependency in Synovial Sarcoma.

Cancer Cell 2018 03;33(3):344-346

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.02.013DOI Listing
March 2018

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).

Genes Chromosomes Cancer 2017 10 24;56(10):719-729. Epub 2017 Jul 24.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561006PMC
October 2017

Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.

Genes Chromosomes Cancer 2017 Jun 31;56(6):472-483. Epub 2017 Mar 31.

Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399546PMC
June 2017

Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis).

J Clin Oncol 2017 May 28;35(14):1561-1569. Epub 2017 Mar 28.

Shivaani Kummar, Geraldine O'Sullivan Coyne, Khanh T. Do, Baris Turkbey, Paul S. Meltzer, Eric Polley, Peter L. Choyke, Robert Meehan, Yvonne Horneffer, Ann Lih, Amul Choudhary, Sandra A. Mitchell, Lee J. Helman, James H. Doroshow, and Alice P. Chen, National Cancer Institute, National Institutes of Health, Bethesda; and Rasa Vilimas and Lamin Juwara, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.71.1994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455706PMC
May 2017

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Am J Hum Genet 2016 05 14;98(5):830-842. Epub 2016 Apr 14.

Department of Genetics and Computational Biology, QIMR Berghofer, Herston, QLD 4029, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863475PMC
May 2016

caOmicsV: an R package for visualizing multidimensional cancer genomic data.

BMC Bioinformatics 2016 Mar 22;17:141. Epub 2016 Mar 22.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 6138, 37 Convent Drive, Bethesda, MD, 20892-4265, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-016-0989-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804509PMC
March 2016

NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

PLoS One 2014 17;9(7):e101670. Epub 2014 Jul 17.

Developmental Therapeutic Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Developmental Therapeutic Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101670PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102467PMC
December 2015

Impact of telomere length on survival in classic and variant hairy cell leukemia.

Leuk Res 2015 Dec 24;39(12):1360-6. Epub 2015 Sep 24.

Laboratory of Molecular Biology, National Cancer Institute (NCI), NIH, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.leukres.2015.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661072PMC
December 2015

Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer.

Carcinogenesis 2015 Oct 4;36(10):1103-10. Epub 2015 Aug 4.

Unitat de Biologia Cellular i Genètica Mèdica, Departament de Biologia Cellular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Catalonia 08193, Spain, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Catalonia 08193, Spain,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgv115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598814PMC
October 2015

Distinct methylation profiles characterize fusion-positive and fusion-negative rhabdomyosarcoma.

Mod Pathol 2015 Sep 31;28(9):1214-24. Epub 2015 Jul 31.

Cancer Molecular Pathology Section, Laboratory of Pathology, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2015.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345526PMC
September 2015

Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma.

Br J Cancer 2015 Sep 20;113(6):894-901. Epub 2015 Aug 20.

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/bjc.2015.298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578089PMC
September 2015

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers.

J Thorac Oncol 2015 Jul;10(7):1037-48

*Laboratory of Human Carcinogenesis, NCI-CCR, National Institutes of Health, Bethesda, Maryland; †Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo, Japan; ‡Genetics Branch, NCI-CCR, National Institutes of Health, Bethesda, Maryland; §Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; ‖Department of Chemical and Biological Working Environment, National Institute of Occupational Health, Oslo, Norway; and ¶Genomics and Epigenomics of Cancer Prediction Program, Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Badalona (Barcelona), Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JTO.0000000000000560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493931PMC
July 2015

Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.

J Clin Oncol 2015 Mar 9;33(9):1000-7. Epub 2015 Feb 9.

Ariel Lopez-Chavez, Anish Thomas, Arun Rajan, Mark Raffeld, Betsy Morrow, Ronan Kelly, Corey Allan Carter, Udayan Guha, Keith Killian, Christopher C. Lau, Zied Abdullaev, Liqiang Xi, Svetlana Pack, Paul S. Meltzer, David J. Liewehr, Seth M. Steinberg, Arlene Berman, Eva Szabo, Yisong Wang, and Giuseppe Giaccone, National Cancer Institute; Austin Doyle, Cancer Therapy Evaluation Program, Bethesda, MD; Ariel Lopez-Chavez, Christopher L. Corless, Alan Sandler, Carol Beadling, and Andrea Warrick, Knight Cancer Institute, Oregon Health and Science University, Portland, OR; Ariel Lopez-Chavez, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL; and Yisong Wang and Giuseppe Giaccone, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.

View Article

Download full-text PDF

Source
http://jco.ascopubs.org/content/early/2015/02/03/JCO.2014.58
Web Search
http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.2007
Publisher Site
http://dx.doi.org/10.1200/JCO.2014.58.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356709PMC
March 2015

Avalanching mutations in biallelic mismatch repair deficiency syndrome.

Nat Genet 2015 Mar;47(3):194-6

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3227DOI Listing
March 2015

EWS-FLI1 employs an E2F switch to drive target gene expression.

Nucleic Acids Res 2015 Mar 20;43(5):2780-9. Epub 2015 Feb 20.

Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna 1090, Austria Dept. of Pediatrics, Medical University, Vienna 1090, Austria

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkv123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357724PMC
March 2015

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.

Authors:
Zhaoming Wang Bin Zhu Mingfeng Zhang Hemang Parikh Jinping Jia Charles C Chung Joshua N Sampson Jason W Hoskins Amy Hutchinson Laurie Burdette Abdisamad Ibrahim Christopher Hautman Preethi S Raj Christian C Abnet Andrew A Adjei Anders Ahlbom Demetrius Albanes Naomi E Allen Christine B Ambrosone Melinda Aldrich Pilar Amiano Christopher Amos Ulrika Andersson Gerald Andriole Irene L Andrulis Cecilia Arici Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Laura E Beane Freeman Christine D Berg Sonja I Berndt Pier Alberto Bertazzi Richard B Biritwum Amanda Black William Blot Heiner Boeing Paolo Boffetta Kelly Bolton Marie-Christine Boutron-Ruault Paige M Bracci Paul Brennan Louise A Brinton Michelle Brotzman H Bas Bueno-de-Mesquita Julie E Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Guangwen Cao Neil E Caporaso Alfredo Carrato Tania Carreon Angela Carta Gee-Chen Chang I-Shou Chang Jenny Chang-Claude Xu Che Chien-Jen Chen Chih-Yi Chen Chung-Hsing Chen Constance Chen Kuan-Yu Chen Yuh-Min Chen Anand P Chokkalingam Lisa W Chu Francoise Clavel-Chapelon Graham A Colditz Joanne S Colt David Conti Michael B Cook Victoria K Cortessis E David Crawford Olivier Cussenot Faith G Davis Immaculata De Vivo Xiang Deng Ti Ding Colin P Dinney Anna Luisa Di Stefano W Ryan Diver Eric J Duell Joanne W Elena Jin-Hu Fan Heather Spencer Feigelson Maria Feychting Jonine D Figueroa Adrienne M Flanagan Joseph F Fraumeni Neal D Freedman Brooke L Fridley Charles S Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina Garcia-Closas Julie M Gastier-Foster J Michael Gaziano Daniela S Gerhard Carol A Giffen Graham G Giles Elizabeth M Gillanders Edward L Giovannucci Michael Goggins Nalan Gokgoz Alisa M Goldstein Carlos Gonzalez Richard Gorlick Mark H Greene Myron Gross H Barton Grossman Robert Grubb Jian Gu Peng Guan Christopher A Haiman Goran Hallmans Susan E Hankinson Curtis C Harris Patricia Hartge Claudia Hattinger Richard B Hayes Qincheng He Lee Helman Brian E Henderson Roger Henriksson Judith Hoffman-Bolton Chancellor Hohensee Elizabeth A Holly Yun-Chul Hong Robert N Hoover H Dean Hosgood Chin-Fu Hsiao Ann W Hsing Chao Agnes Hsiung Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang David J Hunter Peter D Inskip Hidemi Ito Eric J Jacobs Kevin B Jacobs Mazda Jenab Bu-Tian Ji Christoffer Johansen Mattias Johansson Alison Johnson Rudolf Kaaks Ashish M Kamat Aruna Kamineni Margaret Karagas Chand Khanna Kay-Tee Khaw Christopher Kim In-Sam Kim Jin Hee Kim Yeul Hong Kim Young-Chul Kim Young Tae Kim Chang Hyun Kang Yoo Jin Jung Cari M Kitahara Alison P Klein Robert Klein Manolis Kogevinas Woon-Puay Koh Takashi Kohno Laurence N Kolonel Charles Kooperberg Christian P Kratz Vittorio Krogh Hideo Kunitoh Robert C Kurtz Nilgun Kurucu Qing Lan Mark Lathrop Ching C Lau Fernando Lecanda Kyoung-Mu Lee Maxwell P Lee Loic Le Marchand Seth P Lerner Donghui Li Linda M Liao Wei-Yen Lim Dongxin Lin Jie Lin Sara Lindstrom Martha S Linet Jolanta Lissowska Jianjun Liu Börje Ljungberg Josep Lloreta Daru Lu Jing Ma Nuria Malats Satu Mannisto Neyssa Marina Giuseppe Mastrangelo Keitaro Matsuo Katherine A McGlynn Roberta McKean-Cowdin Lorna H McNeill Robert R McWilliams Beatrice S Melin Paul S Meltzer James E Mensah Xiaoping Miao Dominique S Michaud Alison M Mondul Lee E Moore Kenneth Muir Shelley Niwa Sara H Olson Nick Orr Salvatore Panico Jae Yong Park Alpa V Patel Ana Patino-Garcia Sofia Pavanello Petra H M Peeters Beata Peplonska Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Xia Pu Mark P Purdue You-Lin Qiao Preetha Rajaraman Elio Riboli Harvey A Risch Rebecca J Rodabough Nathaniel Rothman Avima M Ruder Jeong-Seon Ryu Marc Sanson Alan Schned Fredrick R Schumacher Ann G Schwartz Kendra L Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Gianluca Severi Hongbing Shen Min Shen Sanjay Shete Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesumaga Sabina Sierri Alan Dart Loon Sihoe Debra T Silverman Matthias Simon Melissa C Southey Logan Spector Margaret Spitz Meir Stampfer Par Stattin Mariana C Stern Victoria L Stevens Rachael Z Stolzenberg-Solomon Daniel O Stram Sara S Strom Wu-Chou Su Malin Sund Sook Whan Sung Anthony Swerdlow Wen Tan Hideo Tanaka Wei Tang Ze-Zhang Tang Adonina Tardon Evelyn Tay Philip R Taylor Yao Tettey David M Thomas Roberto Tirabosco Anne Tjonneland Geoffrey S Tobias Jorge R Toro Ruth C Travis Dimitrios Trichopoulos Rebecca Troisi Ann Truelove Ying-Huang Tsai Margaret A Tucker Rosario Tumino David Van Den Berg Stephen K Van Den Eeden Roel Vermeulen Paolo Vineis Kala Visvanathan Ulla Vogel Chaoyu Wang Chengfeng Wang Junwen Wang Sophia S Wang Elisabete Weiderpass Stephanie J Weinstein Nicolas Wentzensen William Wheeler Emily White John K Wiencke Alicja Wolk Brian M Wolpin Maria Pik Wong Margaret Wrensch Chen Wu Tangchun Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Hannah P Yang Pan-Chyr Yang Yasushi Yatabe Yuanqing Ye Edward D Yeboah Zhihua Yin Chen Ying Chong-Jen Yu Kai Yu Jian-Min Yuan Krista A Zanetti Anne Zeleniuch-Jacquotte Wei Zheng Baosen Zhou Lisa Mirabello Sharon A Savage Peter Kraft Stephen J Chanock Meredith Yeager Maria Terese Landi Jianxin Shi Nilanjan Chatterjee Laufey T Amundadottir

Hum Mol Genet 2014 Dec 15;23(24):6616-33. Epub 2014 Jul 15.

Division of Cancer Epidemiology and Genetics,

View Article

Download full-text PDF

Source
http://kooperberg.fhcrc.org/papers/2014wang.pdf
Web Search
http://hmg.oxfordjournals.org/content/23/24/6616.full.pdf
Web Search
http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu363
Publisher Site
http://dx.doi.org/10.1093/hmg/ddu363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240198PMC
December 2014

The role of mutation of metabolism-related genes in genomic hypermethylation.

Biochem Biophys Res Commun 2014 Dec 8;455(1-2):16-23. Epub 2014 Aug 8.

Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2014.08.003DOI Listing
December 2014

Mutations of epigenetic regulatory genes are common in thymic carcinomas.

Sci Rep 2014 Dec 8;4:7336. Epub 2014 Dec 8.

1] Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 [2] Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC 20007.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep07336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258655PMC
December 2014

Genetic and epigenetic analysis of monozygotic twins discordant for testicular cancer.

Int J Mol Epidemiol Genet 2014 22;5(3):135-9. Epub 2014 Oct 22.

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services Rockville, Maryland, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214260PMC
November 2014

Replicon: a software to accurately predict DNA replication timing in metazoan cells.

Front Genet 2014 3;5:378. Epub 2014 Nov 3.

Genetics Branch, Center for Cancer Research, National Institutes of Health Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://journal.frontiersin.org/article/10.3389/fgene.2014.00
Publisher Site
http://dx.doi.org/10.3389/fgene.2014.00378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217517PMC
November 2014

Building through breaking: the development of cancer neochromosomes.

Cancer Cell 2014 Nov 10;26(5):593-5. Epub 2014 Nov 10.

Genetics Branch, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2014.10.013DOI Listing
November 2014

NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.

Cancer Discov 2014 May 17;4(5):564-77. Epub 2014 Feb 17.

1Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda; 2Department of Pathology, Johns Hopkins University, Baltimore, Maryland; 3Department of Biomolecular Chemistry, University of Wisconsin, Madison, Wisconsin; and 4Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-13-0419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018760PMC
May 2014

A chromatin structure-based model accurately predicts DNA replication timing in human cells.

Mol Syst Biol 2014 Mar 28;10:722. Epub 2014 Mar 28.

Genetics Branch Center for Cancer Research, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017678PMC
http://dx.doi.org/10.1002/msb.134859DOI Listing
March 2014

Genome-wide methylation patterns in papillary thyroid cancer are distinct based on histological subtype and tumor genotype.

J Clin Endocrinol Metab 2014 Feb 11;99(2):E329-37. Epub 2013 Dec 11.

Endocrine Oncology Branch (R.J.E., M.B., D.P., N.N., M.H., L.Z., E.K.), Genetics Branch (Y.W., H.S.S., S.D., D.C.E., P.S.M.), and Laboratory of Pathology (M.J.M.), National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892; and Perelman School of Medicine (R.J.E.), University of Pennsylvania, Philadelphia, Pennsylvania 19104.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2013-2749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913809PMC
February 2014

High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias.

Nat Genet 2014 Jan 17;46(1):8-10. Epub 2013 Nov 17.

Genetics Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), US National Institutes of Health (NIH), Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905739PMC
January 2014

Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel.

DNA Repair (Amst) 2014 Jan 16;13:1-9. Epub 2013 Dec 16.

Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dnarep.2013.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919147PMC
January 2014

Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33.

Pathology 2013 12;45(7):629-36

*Sydney Medical School - Westmead, University of Sydney, Westmead †Westmead Institute for Cancer Research, Westmead ‡Westmead Millennium Institute, Westmead §Tissue Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead ||Translational Oncology, Sydney West Cancer Network, Western Sydney and Nepean Blue Mountains Local Health Districts, Westmead ¶Anatomical Pathology, St Vincent's Hospital, Darlinghurst **Prince of Wales Clinical School, University of New South Wales, Randwick ††School of Medical Sciences University of New South Wales, Randwick ‡‡School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia §§Genetics Branch, National Cancer Institute, Bethesda MD USA ||||these authors contributed equally to this work.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00313025163147
Publisher Site
http://dx.doi.org/10.1097/PAT.0000000000000004DOI Listing
December 2013

CD8(+) lymphocytes suppress human immunodeficiency virus 1 replication by secreting type I interferons.

J Interferon Cytokine Res 2013 Nov 12;33(11):632-45. Epub 2013 Feb 12.

1 Department of Medicine, University of California San Francisco , San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jir.2012.0067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814821PMC
November 2013

Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer.

Genome Res 2013 Nov 12;23(11):1797-809. Epub 2013 Aug 12.

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.151340.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814880PMC
November 2013

Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model.

Carcinogenesis 2013 Oct 22;34(10):2389-400. Epub 2013 May 22.

Gene Regulation Section, Laboratory of Molecular Biology and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgt175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786374PMC
October 2013

The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.

Cancer Res 2013 Jul 15;73(14):4372-82. Epub 2013 Jul 15.

Genetics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, and Division of Cancer Treatment and Diagnosis, National Cancer Institute, NIH, Bethesda, MD 20982, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-3342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893961PMC
July 2013

Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors.

Clin Cancer Res 2013 Apr 26;19(8):1960-71. Epub 2013 Feb 26.

Medical Oncology Branch; Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-3260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630263PMC
April 2013

Chromothripsis and focal copy number alterations determine poor outcome in malignant melanoma.

Cancer Res 2013 Mar 27;73(5):1454-60. Epub 2012 Dec 27.

Genetics Branch, Center for Cancer Research, National Cancer Institute/NIH, Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-0928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535704PMC
March 2013

SRAdb: query and use public next-generation sequencing data from within R.

BMC Bioinformatics 2013 Jan 17;14:19. Epub 2013 Jan 17.

Genetics Branch, National Cancer Institute, National Institutes of HealthBethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-14-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560148PMC
January 2013

Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma.

BMC Genomics 2012 Sep 24;13:505. Epub 2012 Sep 24.

The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-13-505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500261PMC
September 2012

Targeting epigenetic misregulation in synovial sarcoma.

Cancer Cell 2012 Mar;21(3):323-4

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2012.02.023DOI Listing
March 2012

Genomic investigation of dedifferentiated liposarcoma suggests a role for therapeutic targeting of the tumor epigenome.

Cancer Discov 2011 Dec;1(7):555-6

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-11-0291DOI Listing
December 2011