Publications by authors named "Paul S Frenette"

99Publications

Very low incidence of Clostridioides difficile infection in pediatric sickle cell disease patients.

Haematologica 2020 Sep 14;Online ahead of print. Epub 2020 Sep 14.

Department of Pediatrics, The Children's Hospital at Montefiore, Bronx, USA; Department of Pediatrics, The Albert Einstein College of Medicine, Bronx.

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http://dx.doi.org/10.3324/haematol.2019.244582DOI Listing
September 2020

Nociceptors protect sickle cell disease mice from vaso-occlusive episodes and chronic organ damage.

J Exp Med 2021 Jan;218(1)

The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY.

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http://dx.doi.org/10.1084/jem.20200065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534906PMC
January 2021

Randomized phase 2 trial of Intravenous Gamma Globulin (IVIG) for the treatment of acute vaso-occlusive crisis in patients with sickle cell disease: Lessons learned from the midpoint analysis.

Complement Ther Med 2020 Aug 9;52:102481. Epub 2020 Jun 9.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, United States; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, United States; Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY, United States.

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http://dx.doi.org/10.1016/j.ctim.2020.102481DOI Listing
August 2020

The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation.

Immunity 2020 Aug 30;53(2):417-428.e4. Epub 2020 Jul 30.

The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461158PMC
August 2020

Clinically Actionable Strategies for Studying Neural Influences in Cancer.

Cancer Cell 2020 Jul 11;38(1):11-14. Epub 2020 Jun 11.

Center for Neuroscience at the University of Pittsburgh, Pittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.ccell.2020.05.023DOI Listing
July 2020

Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression.

Dev Cell 2020 Jun 14;53(5):503-513.e5. Epub 2020 May 14.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2020.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299199PMC
June 2020

Use of beta-blocker types and risk of incident prostate cancer in a multiethnic population.

Urol Oncol 2020 Oct 17;38(10):794.e11-794.e16. Epub 2020 Apr 17.

Department of Urology, Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY.

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http://dx.doi.org/10.1016/j.urolonc.2020.03.024DOI Listing
October 2020

Nerves in cancer.

Nat Rev Cancer 2020 03 23;20(3):143-157. Epub 2020 Jan 23.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41568-019-0237-2DOI Listing
March 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.

Cell 2019 08;178(5):1102-1114.e17

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357241PMC
August 2019

The good side of inflammation: Staphylococcus aureus proteins SpA and Sbi contribute to proper abscess formation and wound healing during skin and soft tissue infections.

Biochim Biophys Acta Mol Basis Dis 2019 10 9;1865(10):2657-2670. Epub 2019 Jul 9.

Instituto de Investigaciones en Microbiología y Parasitología Médica (IMPaM), Consejo Nacional de Investigaciones Científicas y Tecnológicas, Universidad de Buenos Aires, Argentina; Departamento de Investigaciones Biomédicas y Biotecnológicas, Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y de Diagnóstico (CEBBAD), Universidad Maimónides, Argentina; Universidad de Buenos Aires, Facultad de Medicina, Departamento de Microbiología, Parasitología e Inmunología, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708737PMC
October 2019

NestinNG2 Cells Form a Reserve Stem Cell Population in the Mouse Prostate.

Stem Cell Reports 2019 06 23;12(6):1201-1211. Epub 2019 May 23.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711193014
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http://dx.doi.org/10.1016/j.stemcr.2019.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565923PMC
June 2019

Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells.

Nat Cell Biol 2019 05 15;21(5):560-567. Epub 2019 Apr 15.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://www.nature.com/articles/s41556-019-0308-3
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http://dx.doi.org/10.1038/s41556-019-0308-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499646PMC
May 2019

Seasonal manifestations of sickle cell disease activity.

Nat Med 2019 04;25(4):536-537

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research and Departments of Medicine and of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1038/s41591-019-0409-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602066PMC
April 2019

Author Correction: Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.

Nat Med 2019 Apr;25(4):701

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41591-019-0425-3DOI Listing
April 2019

Cross talk between neutrophils and the microbiota.

Blood 2019 05 21;133(20):2168-2177. Epub 2019 Mar 21.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research.

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http://dx.doi.org/10.1182/blood-2018-11-844555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524562PMC
May 2019

Haematopoietic stem cell activity and interactions with the niche.

Nat Rev Mol Cell Biol 2019 05;20(5):303-320

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, NY, USA.

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http://www.nature.com/articles/s41580-019-0103-9
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http://dx.doi.org/10.1038/s41580-019-0103-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483843PMC
May 2019

Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands.

Blood 2019 03 23;133(11):1222-1232. Epub 2019 Jan 23.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research.

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http://dx.doi.org/10.1182/blood-2018-11-888180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418477PMC
March 2019

The Majority of CD45 Ter119 CD31 Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors.

Immunity 2018 10 9;49(4):627-639.e6. Epub 2018 Oct 9.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, 10461, USA; The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, 10461, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183038
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http://dx.doi.org/10.1016/j.immuni.2018.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377266PMC
October 2018

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.

Nat Commun 2018 06 22;9(1):2449. Epub 2018 Jun 22.

The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, NY, 10461, USA.

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http://dx.doi.org/10.1038/s41467-018-04726-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015052PMC
June 2018

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.

Nat Med 2018 06 7;24(6):782-791. Epub 2018 May 7.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41591-018-0030-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095812PMC
June 2018

Niches for Hematopoietic Stem Cells and Their Progeny.

Immunity 2018 04;48(4):632-648

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Departmentof Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103525PMC
April 2018

Neural Regulation of Bone and Bone Marrow.

Cold Spring Harb Perspect Med 2018 09 4;8(9). Epub 2018 Sep 4.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461.

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http://dx.doi.org/10.1101/cshperspect.a031344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119651PMC
September 2018

CD150 Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.

Cell Stem Cell 2018 03 15;22(3):445-453.e5. Epub 2018 Feb 15.

Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA; Columbia Stem Cell Initiative, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA; Department of Pediatrics, Division of Hematology and Oncology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909183001
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http://dx.doi.org/10.1016/j.stem.2018.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534147PMC
March 2018

Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches.

Dev Cell 2018 03 15;44(5):634-641.e4. Epub 2018 Feb 15.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine, Albert Einstein College of Medicine, Michael F. Price Center, 1301 Morris Park Avenue, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Michael F. Price Center, 1301 Morris Park Avenue, Room 101, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Michael F. Price Center, 1301 Morris Park Avenue, Room 101, Bronx, NY 10461, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807183005
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http://dx.doi.org/10.1016/j.devcel.2018.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886750PMC
March 2018

The hematopoietic stem cell niche: from embryo to adult.

Development 2018 01 22;145(2). Epub 2018 Jan 22.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA

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http://dx.doi.org/10.1242/dev.139691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825844PMC
January 2018

A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche.

Nat Commun 2018 01 4;9(1):66. Epub 2018 Jan 4.

Cancer Research Institute, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA.

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http://www.nature.com/articles/s41467-017-02427-x
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http://dx.doi.org/10.1038/s41467-017-02427-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754357PMC
January 2018

Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow.

Nat Med 2018 01 20;24(1):95-102. Epub 2017 Nov 20.

Department of Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1038/nm.4448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760474PMC
January 2018

Adrenergic nerves activate an angio-metabolic switch in prostate cancer.

Science 2017 10;358(6361):321-326

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1126/science.aah5072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783182PMC
October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Mübeccel Akdis Immanuel Andrä Francesco Annunziato Petra Bacher Vincenzo Barnaba Luca Battistini Wolfgang M Bauer Sabine Baumgart Burkhard Becher Wolfgang Beisker Claudia Berek Alfonso Blanco Giovanna Borsellino Philip E Boulais Ryan R Brinkman Martin Büscher Dirk H Busch Timothy P Bushnell Xuetao Cao Andrea Cavani Pratip K Chattopadhyay Qingyu Cheng Sue Chow Mario Clerici Anne Cooke Antonio Cosma Lorenzo Cosmi Ana Cumano Van Duc Dang Derek Davies Sara De Biasi Genny Del Zotto Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing Andreas Diefenbach James Di Santo Francesco Dieli Andreas Dolf Vera S Donnenberg Thomas Dörner Götz R A Ehrhardt Elmar Endl Pablo Engel Britta Engelhardt Charlotte Esser Bart Everts Anita Dreher Christine S Falk Todd A Fehniger Andrew Filby Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Paul S Frenette David Galbraith Natalio Garbi Maria Dolores García-Godoy Jens Geginat Kamran Ghoreschi Lara Gibellini Christoph Goettlinger Carl S Goodyear Andrea Gori Jane Grogan Mor Gross Andreas Grützkau Daryl Grummitt Jonas Hahn Quirin Hammer Anja E Hauser David L Haviland David Hedley Guadalupe Herrera Martin Herrmann Falk Hiepe Tristan Holland Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Christopher A Hunter Anna Iannone Hans-Martin Jäck Beatriz Jávega Stipan Jonjic Kerstin Juelke Steffen Jung Toralf Kaiser Tomas Kalina Baerbel Keller Srijit Khan Deborah Kienhöfer Thomas Kroneis Désirée Kunkel Christian Kurts Pia Kvistborg Joanne Lannigan Olivier Lantz Anis Larbi Salome LeibundGut-Landmann Michael D Leipold Megan K Levings Virginia Litwin Yanling Liu Michael Lohoff Giovanna Lombardi Lilly Lopez Amy Lovett-Racke Erik Lubberts Burkhard Ludewig Enrico Lugli Holden T Maecker Glòria Martrus Giuseppe Matarese Christian Maueröder Mairi McGrath Iain McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Kingston Mills David Mirrer Jenny Mjösberg Jonni Moore Barry Moran Alessandro Moretta Lorenzo Moretta Tim R Mosmann Susann Müller Werner Müller Christian Münz Gabriele Multhoff Luis Enrique Munoz Kenneth M Murphy Toshinori Nakayama Milena Nasi Christine Neudörfl John Nolan Sussan Nourshargh José-Enrique O'Connor Wenjun Ouyang Annette Oxenius Raghav Palankar Isabel Panse Pärt Peterson Christian Peth Jordi Petriz Daisy Philips Winfried Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Carlo Pucillo Sally A Quataert Timothy R D J Radstake Bartek Rajwa Jonathan A Rebhahn Diether Recktenwald Ester B M Remmerswaal Katy Rezvani Laura G Rico J Paul Robinson Chiara Romagnani Anna Rubartelli Beate Ruckert Jürgen Ruland Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Birgit Sawitzki Alexander Scheffold Matthias Schiemann Frank Schildberg Esther Schimisky Stephan A Schmid Steffen Schmitt Kilian Schober Thomas Schüler Axel Ronald Schulz Ton Schumacher Cristiano Scotta T Vincent Shankey Anat Shemer Anna-Katharina Simon Josef Spidlen Alan M Stall Regina Stark Christina Stehle Merle Stein Tobit Steinmetz Hannes Stockinger Yousuke Takahama Attila Tarnok ZhiGang Tian Gergely Toldi Julia Tornack Elisabetta Traggiai Joe Trotter Henning Ulrich Marlous van der Braber René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Konrad von Volkmann Ari Waisman Rachael Walker Michael D Ward Klaus Warnatz Sarah Warth James V Watson Carsten Watzl Leonie Wegener Annika Wiedemann Jürgen Wienands Gerald Willimsky James Wing Peter Wurst Liping Yu Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann

Eur J Immunol 2017 10;47(10):1584-1797

Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse, Bern.

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http://doi.wiley.com/10.1002/eji.201646632
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October 2017

T-Regulating Hair Follicle Stem Cells.

Immunity 2017 06;46(6):979-981

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.06.011DOI Listing
June 2017

Complexity of bone marrow hematopoietic stem cell niche.

Int J Hematol 2017 Jul 22;106(1):45-54. Epub 2017 May 22.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, 1301 Morris Park Avenue, Bronx, NY, 10461, USA.

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http://dx.doi.org/10.1007/s12185-017-2262-9DOI Listing
July 2017

Differential cytokine contributions of perivascular haematopoietic stem cell niches.

Nat Cell Biol 2017 03 20;19(3):214-223. Epub 2017 Feb 20.

Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/ncb3475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467892PMC
March 2017

Cholinergic Signals from the CNS Regulate G-CSF-Mediated HSC Mobilization from Bone Marrow via a Glucocorticoid Signaling Relay.

Cell Stem Cell 2017 05 9;20(5):648-658.e4. Epub 2017 Feb 9.

The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, New York, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, New York, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467872PMC
May 2017

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.

Science 2016 12 13;354(6316):1156-1160. Epub 2016 Oct 13.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1126/science.aaf5530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164878PMC
December 2016

HSC Contribution in Making Steady-State Blood.

Immunity 2016 09;45(3):464-466

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048748PMC
http://dx.doi.org/10.1016/j.immuni.2016.09.002DOI Listing
September 2016

Targeting Mac-1-mediated leukocyte-RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage.

Exp Hematol 2016 10 5;44(10):940-6. Epub 2016 Jul 5.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Department of Medicine and Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.06.252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467695PMC
October 2016

A Time Bomb for Leukemia.

Cell 2016 Apr;165(2):262-3

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.03.024DOI Listing
April 2016

Niche heterogeneity in the bone marrow.

Ann N Y Acad Sci 2016 04 25;1370(1):82-96. Epub 2016 Mar 25.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York.

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http://doi.wiley.com/10.1111/nyas.13016
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938003PMC
April 2016

Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children.

mBio 2016 Feb 16;7(1):e01300-15. Epub 2016 Feb 16.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA

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http://dx.doi.org/10.1128/mBio.01300-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791846PMC
February 2016

Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology.

Blood 2016 Feb 12;127(7):801-9. Epub 2016 Jan 12.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Department of Cell Biology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.

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http://dx.doi.org/10.1182/blood-2015-09-618538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760086PMC
February 2016

Fetal liver hematopoietic stem cell niches associate with portal vessels.

Science 2016 Jan 3;351(6269):176-80. Epub 2015 Dec 3.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research. Albert Einstein College of Medicine, Bronx, NY, USA. Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA. Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1126/science.aad0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706788PMC
January 2016

Neutrophil ageing is regulated by the microbiome.

Nature 2015 Sep 16;525(7570):528-32. Epub 2015 Sep 16.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nature15367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712631PMC
September 2015

No "Kindlin," it's all about HSC balance.

Authors:
Paul S Frenette

J Exp Med 2015 Aug;212(9):1341-2

Albert Einstein College of Medicine

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http://dx.doi.org/10.1084/jem.2129insight3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548050PMC
August 2015

Neural regulation of hematopoiesis, inflammation, and cancer.

Neuron 2015 Apr;86(2):360-73

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.01.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416657PMC
April 2015

Making sense of hematopoietic stem cell niches.

Blood 2015 Apr 11;125(17):2621-9. Epub 2015 Mar 11.

Department of Cell Biology, The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, and Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-09-57
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http://dx.doi.org/10.1182/blood-2014-09-570192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408288PMC
April 2015

Regulation of leucocyte homeostasis in the circulation.

Cardiovasc Res 2015 Aug 5;107(3):340-51. Epub 2015 Mar 5.

Department of Atherothrombosis, Imaging and Epidemiology, Fundación Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid 28029, Spain Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten (IPEK), Munich 80336, Germany

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http://dx.doi.org/10.1093/cvr/cvv099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560027PMC
August 2015

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.

Nat Med 2014 Nov 19;20(11):1315-20. Epub 2014 Oct 19.

1] Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, USA. [2] Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA. [3] Mount Sinai School of Medicine, New York, New York, USA. [4] Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1038/nm.3707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258871PMC
November 2014

Hematopoietic stem cell niche maintenance during homeostasis and regeneration.

Nat Med 2014 Aug;20(8):833-46

1] Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, USA. [2] The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Bronx, New York, USA. [3] Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://www.nature.com/articles/nm.3647
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459580PMC
August 2014

Stem cells: Reprogramming finds its niche.

Nature 2014 Jul 2;511(7509):301-2. Epub 2014 Jul 2.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, New York 10461, USA.

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http://dx.doi.org/10.1038/nature13516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445071PMC
July 2014

Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche.

Cell Stem Cell 2014 Sep 10;15(3):365-375. Epub 2014 Jul 10.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156919PMC
September 2014

Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development.

Dev Cell 2014 May;29(3):340-9

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051418PMC
May 2014

Influences of vascular niches on hematopoietic stem cell fate.

Int J Hematol 2014 Jun 23;99(6):699-705. Epub 2014 Apr 23.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Bronx, NY, 10461, USA,

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http://dx.doi.org/10.1007/s12185-014-1580-4DOI Listing
June 2014

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease.

Blood 2014 Jun 11;123(24):3818-27. Epub 2014 Mar 11.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY;

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http://dx.doi.org/10.1182/blood-2013-10-529982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055928PMC
June 2014

Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies.

Hematology Am Soc Hematol Educ Program 2013 ;2013:362-9

Departments of 1Pediatrics.

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http://dx.doi.org/10.1182/asheducation-2013.1.362DOI Listing
July 2014

Arteriolar niches maintain haematopoietic stem cell quiescence.

Nature 2013 Oct 9;502(7473):637-43. Epub 2013 Oct 9.

1] Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA [2] Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nature12612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821873PMC
October 2013

Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies.

Blood 2013 Dec 19;122(24):3892-8. Epub 2013 Sep 19.

Departments of Pediatrics.

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http://dx.doi.org/10.1182/blood-2013-05-498311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854110PMC
December 2013

Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis.

Cell Rep 2013 Sep 5;4(5):1022-34. Epub 2013 Sep 5.

Department of Genetic Medicine, Ansary Stem Cell Instiute, Weill Cornell Medical College, New York, NY 10021, USA; Department of Surgery, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.07.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805263PMC
September 2013

Autonomic nerve development contributes to prostate cancer progression.

Science 2013 Jul;341(6142):1236361

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1126/science.1236361DOI Listing
July 2013

PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion.

J Exp Med 2013 Jul 17;210(7):1351-67. Epub 2013 Jun 17.

Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1084/jem.20122252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698522PMC
July 2013

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.

Nat Med 2013 Jun 5;19(6):695-703. Epub 2013 May 5.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.3155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964478PMC
June 2013

This niche is a maze; an amazing niche.

Cell Stem Cell 2013 Apr;12(4):391-2

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.stem.2013.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964479PMC
April 2013

CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress.

Nat Med 2013 Apr 17;19(4):429-36. Epub 2013 Mar 17.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://www.nature.com/articles/nm.3057
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983996PMC
April 2013

Circadian control of the immune system.

Nat Rev Immunol 2013 Mar 8;13(3):190-8. Epub 2013 Feb 8.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nri3386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090048PMC
March 2013

Mesenchymal stem cell: keystone of the hematopoietic stem cell niche and a stepping-stone for regenerative medicine.

Annu Rev Immunol 2013 3;31:285-316. Epub 2013 Jan 3.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1146/annurev-immunol-032712-095919DOI Listing
June 2013

The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine.

Nat Med 2013 Jan 7;19(1):35-42. Epub 2013 Jan 7.

Department of Molecular Medicine, La Sapienza Universita' di Roma, Rome, Italy.

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http://www.nature.com/articles/nm.3028
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998103PMC
January 2013

Adrenergic nerves govern circadian leukocyte recruitment to tissues.

Immunity 2012 Aug 2;37(2):290-301. Epub 2012 Aug 2.

Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, New York, NY 10461, USA.

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http://dx.doi.org/10.1016/j.immuni.2012.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428436PMC
August 2012

Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice.

Blood 2012 Oct 25;120(14):2879-88. Epub 2012 Jul 25.

Hematology and Hemotherapy Center, Instituto Nacional de Ciência e Tecnologia do Sangue (INCTS), UNICAMP, Campinas, São Paulo, Brazil.

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http://dx.doi.org/10.1182/blood-2012-02-409524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466969PMC
October 2012

The secrets of the bone marrow niche: Enigmatic niche brings challenge for HSC expansion.

Nat Med 2012 Jun 6;18(6):864-5. Epub 2012 Jun 6.

Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, New York, USA.

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http://dx.doi.org/10.1038/nm.2825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109721PMC
June 2012

Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields.

Blood 2012 Apr 14;119(17):3962-5. Epub 2012 Mar 14.

Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, New York, NY 10461, USA.

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http://dx.doi.org/10.1182/blood-2011-07-367102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350363PMC
April 2012

Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1.

Circ Res 2012 Apr 13;110(8):1057-66. Epub 2012 Mar 13.

Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.112.266411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351009PMC
April 2012

Trafficking of stem cells.

Methods Mol Biol 2011 ;750:3-24

Department of Medicine, Tisch Cancer Institute, Immunology Institute and Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-61779-145-1_1DOI Listing
September 2011

Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands.

Immunity 2011 Apr 31;34(4):590-601. Epub 2011 Mar 31.

Immunology Program, Sloan Kettering Institute, Infectious Diseases Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.immuni.2011.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081416PMC
April 2011

Physiological contribution of CD44 as a ligand for E-Selectin during inflammatory T-cell recruitment.

Am J Pathol 2011 May 31;178(5):2437-46. Epub 2011 Mar 31.

Department of Epidemiology, Atherothrombosis and Imaging, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.

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http://dx.doi.org/10.1016/j.ajpath.2011.01.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081198PMC
May 2011

CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.

J Clin Invest 2011 Apr 7;121(4):1397-401. Epub 2011 Mar 7.

Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI45336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069787PMC
April 2011

GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice.

Blood 2010 Sep 27;116(10):1779-86. Epub 2010 May 27.

Departments of Medicine and Gene and Cell Medicine, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1182/blood-2009-12-260513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947397PMC
September 2010

Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization.

Ann N Y Acad Sci 2010 Mar;1192:139-44

Medicine, Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2010.05390.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106131PMC
March 2010

Bad blood: a trigger for TRALI.

Nat Med 2010 Apr;16(4):382-3

Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/nm0410-382DOI Listing
April 2010

Neutrophil microdomains: linking heterocellular interactions with vascular injury.

Curr Opin Hematol 2010 Jan;17(1):25-30

Department of Medicine, Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1097/MOH.0b013e328333d2a3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351007PMC
January 2010

Galpha(s) uncouples hematopoietic stem cell homing and mobilization.

Cell Stem Cell 2009 May;4(5):379-80

Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.stem.2009.04.009DOI Listing
May 2009

Circadian rhythms influence hematopoietic stem cells.

Curr Opin Hematol 2009 Jul;16(4):235-42

Department of Medicine, USA bDepartment of Gene and Cell Medicine, USA.

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http://dx.doi.org/10.1097/MOH.0b013e32832bd0f5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117204PMC
July 2009