Publications by authors named "Paul R Gooley"

98Publications

Structural comparison of the C-terminal domain of functionally divergent lyssavirus P proteins.

Biochem Biophys Res Commun 2020 Aug 2;529(2):507-512. Epub 2020 Jul 2.

Faculty of Advanced Life Science, Hokkaido University, Kita-10, Nishi-8, Kita-ku, Sapporo, 060-0810, Japan; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo, 060-0812, Japan; PRESTO, Japan Science and Technology Agency, 4-1-8, Honcho Kawaguchi, Saitama, 332-0012, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.05.195DOI Listing
August 2020

The measles virus V protein binding site to STAT2 overlaps with that of IRF9.

J Virol 2020 Jun 24. Epub 2020 Jun 24.

Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan

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http://dx.doi.org/10.1128/JVI.01169-20DOI Listing
June 2020

N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation.

J Biol Chem 2020 Jul 16;295(29):9838-9854. Epub 2020 May 16.

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria, Australia

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http://dx.doi.org/10.1074/jbc.RA120.012748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380184PMC
July 2020

Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface.

Cell Rep 2019 11;29(7):1934-1945.e8

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.020DOI Listing
November 2019

Heteronuclear NMR spectroscopy of proteins encapsulated in cubic phase lipids.

J Magn Reson 2019 08 1;305:146-151. Epub 2019 Jul 1.

Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmr.2019.06.017DOI Listing
August 2019

Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases.

Diagnostics (Basel) 2019 Jul 4;9(3). Epub 2019 Jul 4.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biochemistry Institute, 30 Flemington Road, Parkville VIC 3010, Australia.

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http://dx.doi.org/10.3390/diagnostics9030070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787670PMC
July 2019

Expression and Purification of a Functional E. coli CH-Methionine-Labeled Thermostable Neurotensin Receptor 1 Variant for Solution NMR Studies.

Methods Mol Biol 2019 ;1947:31-55

Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-9121-1_3DOI Listing
August 2019

Diazepam is not a direct allosteric modulator of α-adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase-4.

Pharmacol Res Perspect 2019 02 26;7(1):e00455. Epub 2018 Dec 26.

The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia.

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http://dx.doi.org/10.1002/prp2.455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306559PMC
February 2019

Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis.

iScience 2019 Jan 10;11:93-113. Epub 2018 Dec 10.

Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309025PMC
January 2019

H, N and C resonance assignments of the C-terminal domain of the P protein of the Nishigahara strain of rabies virus.

Biomol NMR Assign 2019 04 20;13(1):5-8. Epub 2018 Sep 20.

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, VIC, 3010, Australia.

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http://dx.doi.org/10.1007/s12104-018-9841-4DOI Listing
April 2019

Polymorphism in disease-related apolipoprotein C-II amyloid fibrils: a structural model for rod-like fibrils.

FEBS J 2018 08 9;285(15):2799-2812. Epub 2018 Jun 9.

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Vic., Australia.

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http://dx.doi.org/10.1111/febs.14517DOI Listing
August 2018

Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length.

J Mol Biol 2018 05 5;430(10):1442-1458. Epub 2018 Apr 5.

Department of Biochemistry and Molecular Biology, and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.03.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963539PMC
May 2018

Optimization and CH methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies.

Biochim Biophys Acta Biomembr 2018 Jun 26;1860(6):1372-1383. Epub 2018 Mar 26.

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2018.03.020DOI Listing
June 2018

Determinants of Ligand Subtype-Selectivity at α-Adrenoceptor Revealed Using Saturation Transfer Difference (STD) NMR.

ACS Chem Biol 2018 04 22;13(4):1090-1102. Epub 2018 Mar 22.

The Florey Institute of Neuroscience and Mental Health , The University of Melbourne , 30 Royal Parade , Parkville , Victoria 3052 , Australia.

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http://dx.doi.org/10.1021/acschembio.8b00191DOI Listing
April 2018

Applications of NMR and ITC for the Study of the Kinetics of Carbohydrate Binding by AMPK β-Subunit Carbohydrate-Binding Modules.

Methods Mol Biol 2018 ;1732:87-98

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7598-3_6DOI Listing
January 2019

The relaxin receptor as a therapeutic target - perspectives from evolution and drug targeting.

Pharmacol Ther 2018 07 17;187:114-132. Epub 2018 Feb 17.

Department of Biochemistry & Molecular Biology, The University of Melbourne, Victoria, Australia; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01637258183003
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http://dx.doi.org/10.1016/j.pharmthera.2018.02.008DOI Listing
July 2018

The UBA domain of SnRK1 promotes activation and maintains catalytic activity.

Biochem Biophys Res Commun 2018 02 8;497(1):127-132. Epub 2018 Feb 8.

Department of Molecular & Cellular Biochemistry, Centre for Structural Biology, College of Medicine, University of Kentucky, Lexington, KY 40536, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.02.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463285PMC
February 2018

Unravelling the Carbohydrate-Binding Preferences of the Carbohydrate-Binding Modules of AMP-Activated Protein Kinase.

Chembiochem 2018 02 9;19(3):229-238. Epub 2018 Jan 9.

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1002/cbic.201700589DOI Listing
February 2018

Characterisation of a cell-free synthesised G-protein coupled receptor.

Sci Rep 2017 04 24;7(1):1094. Epub 2017 Apr 24.

Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, VIC, 3010, Australia.

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http://dx.doi.org/10.1038/s41598-017-01227-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430785PMC
April 2017

Intra- and Intersubunit Ion-Pair Interactions Determine the Ability of Apolipoprotein C-II Mutants To Form Hybrid Amyloid Fibrils.

Biochemistry 2017 03 15;56(12):1757-1767. Epub 2017 Mar 15.

Department of Biochemistry and Molecular Biology, University of Melbourne , Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1021/acs.biochem.6b01146DOI Listing
March 2017

β-subunit myristoylation functions as an energy sensor by modulating the dynamics of AMP-activated Protein Kinase.

Sci Rep 2016 12 21;6:39417. Epub 2016 Dec 21.

Department of Biochemistry &Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1038/srep39417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175161PMC
December 2016

When phosphorylated at Thr148, the β2-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle.

Am J Physiol Cell Physiol 2016 07 20;311(1):C35-42. Epub 2016 Apr 20.

Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia;

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http://dx.doi.org/10.1152/ajpcell.00047.2016DOI Listing
July 2016

The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1.

Nat Commun 2016 Apr 18;7:11344. Epub 2016 Apr 18.

Department of Biochemistry &Molecular Biology, The University of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1038/ncomms11344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837482PMC
April 2016

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.

Cell Host Microbe 2015 Dec;18(6):670-81

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Victoria, 3052, Australia; Department of Medical Biology, The University of Melbourne, Victoria, 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.11.004DOI Listing
December 2015

Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1.

Trends Plant Sci 2016 Apr 28;21(4):341-353. Epub 2015 Nov 28.

Department of Biochemistry & Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia.

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http://www.cell.com/trends/plant-science/pdf/S1360-1385(15)0
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http://linkinghub.elsevier.com/retrieve/pii/S136013851500281
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http://dx.doi.org/10.1016/j.tplants.2015.11.001DOI Listing
April 2016

Native Chemical Ligation to Minimize Aspartimide Formation during Chemical Synthesis of Small LDLa Protein.

Chemistry 2016 Jan 27;22(3):1146-51. Epub 2015 Nov 27.

Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Victoria, 3010, Australia.

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http://dx.doi.org/10.1002/chem.201503599DOI Listing
January 2016

In a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR Family.

Front Endocrinol (Lausanne) 2015 7;6:137. Epub 2015 Sep 7.

Department of Biochemistry and Molecular Biology, University of Melbourne , Parkville, VIC , Australia ; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville, VIC , Australia.

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http://dx.doi.org/10.3389/fendo.2015.00137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561518PMC
October 2015

Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II.

Biochemistry 2015 Aug 3;54(31):4805-14. Epub 2015 Aug 3.

†Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://pubs.acs.org/doi/10.1021/acs.biochem.5b00535
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http://dx.doi.org/10.1021/acs.biochem.5b00535DOI Listing
August 2015

The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation.

J Biol Chem 2015 May 19;290(18):11715-28. Epub 2015 Mar 19.

From the Department of Molecular Genetics, CARIM School of Cardiovascular Diseases, Maastricht University, 6200 MD Maastricht, The Netherlands, the Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland, and

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http://dx.doi.org/10.1074/jbc.M114.633271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416872PMC
May 2015

Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.

Biochem J 2015 Jun;468(2):245-57

*Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1042/BJ20150270DOI Listing
June 2015

Structure of amylase-binding protein A of Streptococcus gordonii: a potential receptor for human salivary α-amylase enzyme.

Protein Sci 2015 Jun 2;24(6):1013-8. Epub 2015 Apr 2.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Victoria, 3010, Australia.

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http://doi.wiley.com/10.1002/pro.2671
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http://dx.doi.org/10.1002/pro.2671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456114PMC
June 2015

SnRK1 from Arabidopsis thaliana is an atypical AMPK.

Plant J 2015 Apr;82(2):183-92

Australian Research Council Centre of Excellence in Plant Cell Walls, School of Botany, and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, 3010, Australia; Department of Biochemistry & Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1111/tpj.12813DOI Listing
April 2015

Charge and charge-pair mutations alter the rate of assembly and structural properties of apolipoprotein C-II amyloid fibrils.

Biochemistry 2015 Feb 2;54(6):1421-8. Epub 2015 Feb 2.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1021/bi5014535DOI Listing
February 2015

Physical characterisation of high amylose maize starch and acylated high amylose maize starches.

Carbohydr Polym 2015 Mar 7;117:279-85. Epub 2014 Oct 7.

CSIRO Preventative Health National Research Flagship & Animal, Food and Health Sciences, 671 Sneydes Road, Werribee, Melbourne 3030, VIC, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S01448617140097
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http://dx.doi.org/10.1016/j.carbpol.2014.09.068DOI Listing
March 2015

(1)H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium-vitamin-D3 supplementation in older men.

Appl Physiol Nutr Metab 2014 Nov 23;39(11):1294-304. Epub 2014 Jul 23.

a Department of Medicine, NorthWest Academic Centre, Sunshine Hospital, The University of Melbourne, Furlong Road, St Albans, Victoria, Australia, 3021.

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http://dx.doi.org/10.1139/apnm-2014-0060DOI Listing
November 2014

Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation.

Biochemistry 2014 Jul 10;53(28):4537-48. Epub 2014 Jul 10.

Department of Biochemistry and Molecular Biology, The Bio21 Molecular Science and Biotechnology Institute, ‡Florey Institute of Neuroscience and Mental Health, and §School of Chemistry, University of Melbourne , Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1021/bi500797dDOI Listing
July 2014

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules.

Front Endocrinol (Lausanne) 2013 11;4:171. Epub 2013 Nov 11.

Florey Department of Neuroscience and Mental Health, Florey Institute of Neuroscience and Mental Health , Melbourne, VIC , Australia ; Department of Biochemistry and Molecular Biology , Melbourne, VIC , Australia.

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http://dx.doi.org/10.3389/fendo.2013.00171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822782PMC
November 2013

The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.

J Biol Chem 2013 Sep 7;288(39):28138-51. Epub 2013 Aug 7.

From the Florey Institute of Neuroscience and Mental Health and Florey Department of Neuroscience and Mental Health.

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http://dx.doi.org/10.1074/jbc.M113.499640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784725PMC
September 2013

Membrane targeting of the small myristoylated protein 2 (SMP-2) in Leishmania major.

Mol Biochem Parasitol 2013 Jul 30;190(1):1-5. Epub 2013 May 30.

Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.molbiopara.2013.05.005DOI Listing
July 2013

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3.

Front Endocrinol (Lausanne) 2013 22;4:13. Epub 2013 Feb 22.

Florey Institute of Neuroscience and Mental Health, University of Melbourne Parkville, VIC, Australia ; Department of Biochemistry and Molecular Biology, University of Melbourne Parkville, VIC, Australia.

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http://dx.doi.org/10.3389/fendo.2013.00013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579193PMC
February 2013

Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds.

Biochim Biophys Acta 2013 Jun 11;1834(6):1077-88. Epub 2013 Feb 11.

Department of Biochemistry and Molecular Biology, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.bbapap.2013.02.001DOI Listing
June 2013

Cell-free protein synthesis as a tool to study RXFP3-relaxin-3 protein interactions.

Ital J Anat Embryol 2013 ;118(1 Suppl):7-9

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May 2014

Recombinant RXFP1-LDL-A module does not form dimers.

Ital J Anat Embryol 2013 ;118(1 Suppl):4-6

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May 2014

Development of a scaffold displaying exoloops of RXFP1.

Ital J Anat Embryol 2013 ;118(1 Suppl):1-3

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May 2014

Single fiber analyses of glycogen-related proteins reveal their differential association with glycogen in rat skeletal muscle.

Am J Physiol Cell Physiol 2012 Dec 26;303(11):C1146-55. Epub 2012 Sep 26.

Dept. of Zoology, La Trobe Univ., Melbourne 3086, Victoria, Australia.

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http://dx.doi.org/10.1152/ajpcell.00252.2012DOI Listing
December 2012

NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome.

Clin Chim Acta 2012 Oct 21;413(19-20):1525-31. Epub 2012 Jun 21.

Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.cca.2012.06.022DOI Listing
October 2012

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding.

Biophys J 2012 Jan;102(2):305-14

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1016/j.bpj.2011.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265976PMC
January 2012

Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major.

Int J Parasitol 2012 11;42(3):239-47. Epub 2012 Jan 11.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.ijpara.2011.12.004DOI Listing
July 2012

A cyclic peptide inhibitor of apoC-II peptide fibril formation: mechanistic insight from NMR and molecular dynamics analysis.

J Mol Biol 2012 Mar 5;416(5):642-55. Epub 2012 Jan 5.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.jmb.2011.12.059DOI Listing
March 2012

Automated NMR relaxation dispersion data analysis using NESSY.

BMC Bioinformatics 2011 Oct 27;12:421. Epub 2011 Oct 27.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic 3010, Australia.

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http://dx.doi.org/10.1186/1471-2105-12-421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215250PMC
October 2011

relaxGUI: a new software for fast and simple NMR relaxation data analysis and calculation of ps-ns and μs motion of proteins.

J Biomol NMR 2011 Jun 27;50(2):147-55. Epub 2011 May 27.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, 3010, Australia.

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http://link.springer.com/10.1007/s10858-011-9509-1
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http://dx.doi.org/10.1007/s10858-011-9509-1DOI Listing
June 2011

Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination.

FEBS J 2011 Mar 28;278(5):704-15. Epub 2011 Jan 28.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Australia.

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http://doi.wiley.com/10.1111/j.1742-4658.2011.08005.x
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http://dx.doi.org/10.1111/j.1742-4658.2011.08005.xDOI Listing
March 2011

Macromolecular NMR spectroscopy for the non-spectroscopist.

FEBS J 2011 Mar 28;278(5):687-703. Epub 2011 Jan 28.

School of Molecular Bioscience, University of Sydney, New South Wales, Australia.

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http://doi.wiley.com/10.1111/j.1742-4658.2011.08004.x
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http://dx.doi.org/10.1111/j.1742-4658.2011.08004.xDOI Listing
March 2011

Recognition of mitochondrial targeting sequences by the import receptors Tom20 and Tom22.

J Mol Biol 2011 Jan 16;405(3):804-18. Epub 2010 Nov 16.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jmb.2010.11.017DOI Listing
January 2011

AMPK beta subunits display isoform specific affinities for carbohydrates.

FEBS Lett 2010 Aug 14;584(15):3499-503. Epub 2010 Jul 14.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.febslet.2010.07.015DOI Listing
August 2010

Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1.

J Mol Biol 2010 Jun 24;399(3):358-66. Epub 2010 Apr 24.

Department of Genetics, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Melbourne, Victoria 3010, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00222836100038
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http://dx.doi.org/10.1016/j.jmb.2010.04.020DOI Listing
June 2010

Membrane receptors: structure and function of the relaxin family peptide receptors.

Mol Cell Endocrinol 2010 May 6;320(1-2):1-15. Epub 2010 Feb 6.

Florey Neuroscience Institutes, University of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.mce.2010.02.003DOI Listing
May 2010

Membrane protein SMP-1 is required for normal flagellum function in Leishmania.

J Cell Sci 2010 Feb 19;123(Pt 4):544-54. Epub 2010 Jan 19.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1242/jcs.059097DOI Listing
February 2010

A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine.

Anal Biochem 2010 Mar 23;398(2):263-5. Epub 2009 Nov 23.

Department of Medicine, Royal Melbourne and Western Hospitals, University of Melbourne, Footscray, Victoria 3011, Australia.

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http://dx.doi.org/10.1016/j.ab.2009.11.027DOI Listing
March 2010

Discovery of inhibitors of lupin diadenosine 5',5'''-P(1),P(4)-tetraphosphate hydrolase by virtual screening.

Biochemistry 2009 Aug;48(32):7614-20

Structural Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1021/bi900813xDOI Listing
August 2009

Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome.

In Vivo 2009 Jul-Aug;23(4):621-8

Bio21 Institute of Biotechnology and Molecular Science, Department of Biochemistry and Molecular Biology, Victoria, Australia.

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September 2009

Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.

Chem Biol 2008 Nov;15(11):1220-30

St. Vincent's Institute and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy 3065, VIC Australia.

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http://dx.doi.org/10.1016/j.chembiol.2008.10.005DOI Listing
November 2008

Structure, topology and function of the translocase of the outer membrane of mitochondria.

Plant Physiol Biochem 2008 Mar 3;46(3):265-74. Epub 2008 Jan 3.

Department of Biochemistry and Molecular Biology, Bio21 Institute of Biotechnology and Molecular Science, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.plaphy.2007.12.012DOI Listing
March 2008

The transmembrane segment of Tom20 is recognized by Mim1 for docking to the mitochondrial TOM complex.

J Mol Biol 2008 Feb 15;376(3):694-704. Epub 2007 Dec 15.

Department of Biochemistry and Molecular Biology, University of Melbourne, Melbourne 3010, Australia.

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http://dx.doi.org/10.1016/j.jmb.2007.12.021DOI Listing
February 2008

Optimisation of NMR dynamic models II. A new methodology for the dual optimisation of the model-free parameters and the Brownian rotational diffusion tensor.

J Biomol NMR 2008 Feb 18;40(2):121-33. Epub 2007 Dec 18.

Department of NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Goettingen, D-37077, Germany.

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http://dx.doi.org/10.1007/s10858-007-9213-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758375PMC
February 2008

Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spaces.

J Biomol NMR 2008 Feb 18;40(2):107-19. Epub 2007 Dec 18.

Department of NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, D-37077, Goettingen, Germany.

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http://link.springer.com/10.1007/s10858-007-9214-2
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http://dx.doi.org/10.1007/s10858-007-9214-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758376PMC
February 2008

Oligosaccharide recognition and binding to the carbohydrate binding module of AMP-activated protein kinase.

FEBS Lett 2007 Oct 29;581(26):5055-9. Epub 2007 Sep 29.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.febslet.2007.09.044DOI Listing
October 2007

A high-resolution solution structure of a trypanosomatid FYVE domain.

Protein Sci 2007 Nov 28;16(11):2552-9. Epub 2007 Sep 28.

Department of Biochemistry and Molecular Biology, Institute of Biotechnology and Molecular Science, University of Melbourne, Parkville, Victoria, Australia.

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http://doi.wiley.com/10.1110/ps.073009807
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http://dx.doi.org/10.1110/ps.073009807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211690PMC
November 2007

Probing the flexibility of the DsbA oxidoreductase from Vibrio cholerae--a 15N - 1H heteronuclear NMR relaxation analysis of oxidized and reduced forms of DsbA.

J Mol Biol 2007 Aug 31;371(3):703-16. Epub 2007 May 31.

Department of Medicinal Chemistry, Victorian College of Pharmacy, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1016/j.jmb.2007.05.067DOI Listing
August 2007

Set theory formulation of the model-free problem and the diffusion seeded model-free paradigm.

Mol Biosyst 2007 Jul 17;3(7):483-94. Epub 2007 May 17.

Department of Biochemistry and Molecular Biology, Bio21 Institute of Biotechnology and Molecular Science, University of Melbourne, Parkville, Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1039/b702202fDOI Listing
July 2007

High-level expression of a soluble and functional fibronectin type II domain from MMP-2 in the Escherichia coli cytoplasm for solution NMR studies.

Protein Expr Purif 2007 May 13;53(1):124-31. Epub 2006 Dec 13.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic. 3010, Australia.

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http://dx.doi.org/10.1016/j.pep.2006.12.005DOI Listing
May 2007

A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis.

J Mol Biol 2007 Mar 21;366(5):1639-51. Epub 2006 Dec 21.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.jmb.2006.12.040DOI Listing
March 2007

The NMR solution structure of the relaxin (RXFP1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation.

J Biol Chem 2007 Feb 4;282(6):4172-84. Epub 2006 Dec 4.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1074/jbc.M609526200DOI Listing
February 2007

Model-free model elimination: a new step in the model-free dynamic analysis of NMR relaxation data.

J Biomol NMR 2006 Jun 22;35(2):117-35. Epub 2006 Jun 22.

Department of Biochemistry and Molecular Biology, Bio21 Institute of Biotechnology and Molecular Science, University of Melbourne, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1007/s10858-006-9007-zDOI Listing
June 2006

1H, 13C and 15N resonance assignments of SMP-1: a small myristoylated protein from Leishmania major.

J Biomol NMR 2006 6;36 Suppl 1:26. Epub 2006 Apr 6.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1007/s10858-006-0010-1DOI Listing
August 2007

Convergent evolution of receptors for protein import into mitochondria.

Curr Biol 2006 Feb;16(3):221-9

Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science and Biotechnology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.cub.2005.12.034DOI Listing
February 2006

A statistical approach to the interpretation of molecular dynamics simulations of calmodulin equilibrium dynamics.

Protein Sci 2005 Dec;14(12):2955-63

Reprints requests to: Dr Vladimir A. Likić, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1110/ps.051681605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253239PMC
December 2005

Validating the use of database potentials in protein structure determination by NMR.

FEBS Lett 2005 Oct 27;579(25):5542-8. Epub 2005 Sep 27.

Department of Biochemistry and Molecular Biology, Bio21 Institute of Biotechnology and Molecular Science, University of Melbourne, Parkville, Vic., Australia.

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http://dx.doi.org/10.1016/j.febslet.2005.09.017DOI Listing
October 2005

The human LGR7 low-density lipoprotein class A module requires calcium for structure.

Ann N Y Acad Sci 2005 May;1041:27-34

The Howard Florey Institute of Experimental Physiology, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1196/annals.1282.006DOI Listing
May 2005

Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20.

J Mol Biol 2005 Mar 28;347(1):81-93. Epub 2005 Jan 28.

Russell Grimwade School of Biochemistry and Molecular Biology, University of Melbourne, Melbourne 3010, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360500005
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http://dx.doi.org/10.1016/j.jmb.2004.12.057DOI Listing
March 2005

Structure and substrate-binding mechanism of human Ap4A hydrolase.

J Biol Chem 2005 Mar 13;280(9):8471-81. Epub 2004 Dec 13.

Department of Biochemistry and Molecular Biology, the University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1074/jbc.M412318200DOI Listing
March 2005

The structure and interactions of human apolipoprotein C-II in dodecyl phosphocholine.

Biochemistry 2004 Jun;43(25):8084-93

Russell Grimwade School of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1021/bi049817lDOI Listing
June 2004

Dynamics of Ca2+-saturated calmodulin D129N mutant studied by multiple molecular dynamics simulations.

Protein Sci 2003 Oct;12(10):2215-29

Department of Biochemistry and Molecular Biology, Russell Grimwade School of Biochemistry, The University of Melbourne, Parkville, VIC 3052, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366934PMC
http://dx.doi.org/10.1110/ps.0377803DOI Listing
October 2003

The use of model selection in the model-free analysis of protein dynamics.

J Biomol NMR 2003 Jan;25(1):25-39

Department of Biochemistry and Molecular Biology, University of Melbourne, Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1023/a:1021902006114DOI Listing
January 2003

Structural characterization of the N-terminal autoregulatory sequence of phenylalanine hydroxylase.

Protein Sci 2002 Aug;11(8):2041-7

Structural Biology Laboratory, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, 3065, Australia.

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http://dx.doi.org/10.1110/ps.4560102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373677PMC
August 2002

The structure of Ap(4)A hydrolase complexed with ATP-MgF(x) reveals the basis of substrate binding.

Structure 2002 Feb;10(2):205-13

Department of Biochemistry and Molecular Biology, The University of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/s0969-2126(02)00696-2DOI Listing
February 2002