Paul Michels

Paul Michels

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Paul Michels

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Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis.

J Mol Biol 2019 Sep 2;431(19):3690-3705. Epub 2019 Aug 2.

Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, 138602, Singapore; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.07.033DOI Listing
September 2019

Control and regulation of the pyrophosphate-dependent glucose metabolism in Entamoeba histolytica.

Mol Biochem Parasitol 2019 04 14;229:75-87. Epub 2019 Feb 14.

Departamento de Bioquímica, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, 14080, Mexico.

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http://dx.doi.org/10.1016/j.molbiopara.2019.02.002DOI Listing
April 2019

Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes.

Mol Biochem Parasitol 2019 04 1;229:62-74. Epub 2019 Mar 1.

Laboratorio de Enzimología de Parásitos, Facultad de Ciencias, Universidad de Los Andes, Mérida, 5101, Venezuela. Electronic address:

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http://dx.doi.org/10.1016/j.molbiopara.2019.02.008DOI Listing
April 2019

The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction.

Biochem J 2019 01 18;476(2):179-191. Epub 2019 Jan 18.

School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, U.K.

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http://dx.doi.org/10.1042/BCJ20180635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340114PMC
January 2019

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation.

Biochem J 2018 10 31;475(20):3275-3291. Epub 2018 Oct 31.

Centre for Translational and Chemical Biology, School of Biological Sciences, University of Edinburgh, The King's Buildings, Max Born Crescent, Edinburgh EH9 3BF, U.K.

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http://dx.doi.org/10.1042/BCJ20180556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208296PMC
October 2018

Drug Target Selection for Trypanosoma cruzi Metabolism by Metabolic Control Analysis and Kinetic Modeling.

Curr Med Chem 2018 Sep 16. Epub 2018 Sep 16.

Centre for Immunity, Infection and Evolution (CIIE) and Centre for Translational and Chemical Biology (CTCB), School of Biological Sciences, The University of Edinburgh, Edinburgh. Scotland.

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http://dx.doi.org/10.2174/0929867325666180917104242DOI Listing
September 2018

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor.

Biochem J 2018 05 31;475(10):1821-1837. Epub 2018 May 31.

Centre for Translational and Chemical Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, U.K.

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http://dx.doi.org/10.1042/BCJ20180171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980995PMC
May 2018

The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids.

Pathogens 2018 Apr 1;7(2). Epub 2018 Apr 1.

Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, Av. Lineu Prestes, 1374, São Paulo 05508-000, SP, Brazil.

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http://dx.doi.org/10.3390/pathogens7020036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027508PMC
April 2018

Structure and function of Per-ARNT-Sim domains and their possible role in the life-cycle biology of Trypanosoma cruzi.

Mol Biochem Parasitol 2018 01 11;219:52-66. Epub 2017 Nov 11.

Laboratorio de Enzimología de Parásitos, Departamento de Biología, Facultad de Ciencias, Universidad de Los Andes, Mérida 5101, Venezuela. Electronic address:

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http://dx.doi.org/10.1016/j.molbiopara.2017.11.002DOI Listing
January 2018

A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex.

PLoS Pathog 2017 12 21;13(12):e1006679. Epub 2017 Dec 21.

Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, Czech Republic.

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http://dx.plos.org/10.1371/journal.ppat.1006679
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http://dx.doi.org/10.1371/journal.ppat.1006679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739487PMC
December 2017

Peroxisomes in parasitic protists.

Mol Biochem Parasitol 2016 Sep - Oct;209(1-2):35-45. Epub 2016 Feb 16.

Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, UK; Centre for Translational and Chemical Biology, School of Biological Sciences, University of Edinburgh, UK; Laboratorio de Enzimología de Parásitos, Departamento de Biología, Universidad de Los Andes, Mérida, Venezuela. Electronic address:

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http://dx.doi.org/10.1016/j.molbiopara.2016.02.005DOI Listing
November 2017

Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.

Biochim Biophys Acta Gen Subj 2017 Nov 2;1861(11 Pt A):2830-2842. Epub 2017 Aug 2.

Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; School of Tropical Medicine and Global Health, Nagasaki University 1-12-4, Sakamoto, Nagasaki 852-8523, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.07.028DOI Listing
November 2017

Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition.

J Mol Biol 2017 10 4;429(20):3075-3089. Epub 2017 Sep 4.

Centre for Translational and Chemical Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh EH9 3BF, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2017.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639204PMC
October 2017

Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.

Protein Eng Des Sel 2017 03;30(3):225-233

Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, FIN-90014, Finland.

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http://dx.doi.org/10.1093/protein/gzw080DOI Listing
March 2017

The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism.

Proteins 2016 08 9;84(8):1075-96. Epub 2016 May 9.

Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, FIN-90014, Finland.

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http://dx.doi.org/10.1002/prot.25054DOI Listing
August 2016

Trypanosoma evansi contains two auxiliary enzymes of glycolytic metabolism: Phosphoenolpyruvate carboxykinase and pyruvate phosphate dikinase.

Exp Parasitol 2016 Jun 9;165:7-15. Epub 2016 Mar 9.

Laboratorio de Enzimología de Parásitos, Facultad de Ciencias, Universidad de Los Andes, Mérida 5101, Venezuela. Electronic address:

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http://dx.doi.org/10.1016/j.exppara.2016.03.003DOI Listing
June 2016

Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.

Biochim Biophys Acta 2016 May 16;1863(5):1038-48. Epub 2015 Sep 16.

Laboratorio de Enzimología de Parásitos, Facultad de Ciencias, Universidad de Los Andes, Mérida, Venezuela; Centre for Translational and Chemical Biology, Institute of Structural and Molecular Biology, School of Biological Sciences, University of Edinburgh, United Kingdom. Electronic address:

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http://ac.els-cdn.com/S0167488915003080/1-s2.0-S016748891500
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http://linkinghub.elsevier.com/retrieve/pii/S016748891500308
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http://dx.doi.org/10.1016/j.bbamcr.2015.09.015DOI Listing
May 2016

ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei.

PLoS One 2015 19;10(6):e0130365. Epub 2015 Jun 19.

Research Unit for Tropical Diseases, de Duve Institute, and Laboratory of Biochemistry, Université catholique de Louvain, Brussels, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130365PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474607PMC
April 2016

The glycosomal-membrane associated phosphoglycerate kinase isoenzyme A plays a role in sustaining the glucose flux in Trypanosoma cruzi epimastigotes.

Mol Biochem Parasitol 2015 Mar-Apr;200(1-2):5-8. Epub 2015 Apr 25.

Laboratorio de Enzimología de Parásitos, Facultad de Ciencias, Universidad de los Andes, La Hechicera, 5101 Mérida, Venezuela. Electronic address:

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http://dx.doi.org/10.1016/j.molbiopara.2015.04.003DOI Listing
March 2016

Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds.

Bioorg Med Chem Lett 2015 Aug 30;25(16):3342-5. Epub 2015 May 30.

Programa de Pós Graduação em Biotecnologia, Brazil; Faculdade de Ciências Farmacêuticas, Universidade Estadual Paulista, UNESP, Araraquara, SP 14801-902, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.05.072DOI Listing
August 2015

Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.

Mol Microbiol 2014 Dec 4;94(6):1315-29. Epub 2014 Nov 4.

Department of Applied Biology, Graduate School of Science and Technology, Kyoto Institute of Technology, Sakyo-ku, Kyoto, 606-8585, Japan; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan; Department of Biochemistry, Ahmadu Bello University, Zaria, 2222, Nigeria.

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http://dx.doi.org/10.1111/mmi.12831DOI Listing
December 2014

Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids.

Curr Opin Microbiol 2014 Dec;22:79-87

Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, UK

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http://dx.doi.org/10.1016/j.mib.2014.09.006DOI Listing
December 2014

In or out? On the tightness of glycosomal compartmentalization of metabolites and enzymes in Trypanosoma brucei.

Mol Biochem Parasitol 2014 Nov 2;198(1):18-28. Epub 2014 Dec 2.

Institute of Structural and Molecular Biology, School of Biological Sciences, University of Edinburgh, UK; Laboratorio de Enzimología de Parásitos, Departamento de Biología, Universidad de Los Andes, Mérida, Venezuela.

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http://dx.doi.org/10.1016/j.molbiopara.2014.11.004DOI Listing
November 2014

Structures of pyruvate kinases display evolutionarily divergent allosteric strategies.

R Soc Open Sci 2014 Sep 24;1(1):140120. Epub 2014 Sep 24.

Centre for Translational and Chemical Biology, School of Biological Sciences , University of Edinburgh , Michael Swann Building, The King's Buildings, Mayfield Road, Edinburgh EH9 3JR, UK.

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http://dx.doi.org/10.1098/rsos.140120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448766PMC
September 2014

The phosphoglycerate kinase isoenzymes have distinct roles in the regulation of carbohydrate metabolism in Trypanosoma cruzi.

Exp Parasitol 2014 Aug 20;143:39-47. Epub 2014 May 20.

Laboratorio de Enzimología de Parásitos, Facultad de Ciencias, Universidad de Los Andes, Mérida, Venezuela. Electronic address:

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http://dx.doi.org/10.1016/j.exppara.2014.05.010DOI Listing
August 2014

Phylogenetic relationships and classification of thiolases and thiolase-like proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis.

Tuberculosis (Edinb) 2014 Jul 4;94(4):405-12. Epub 2014 Apr 4.

Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, FIN-90014, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2014.03.003DOI Listing
July 2014

Trypanosomatid phosphoglycerate mutases have multiple conformational and oligomeric states.

Biochem Biophys Res Commun 2014 Jul 28;450(2):936-41. Epub 2014 Jun 28.

Centre for Translational and Chemical Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JR, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.06.113DOI Listing
July 2014

Pyruvate kinases have an intrinsic and conserved decarboxylase activity.

Biochem J 2014 Mar;458(2):301-11

*Centre for Translational and Chemical Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, The King's Buildings, Mayfield Road, Edinburgh EH9 3JR, U.K.

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http://dx.doi.org/10.1042/BJ20130790DOI Listing
March 2014

Extracellular functions of glycolytic enzymes of parasites: unpredicted use of ancient proteins.

Mol Biochem Parasitol 2014 Feb 3;193(2):75-81. Epub 2014 Mar 3.

Laboratorio de Fisiología Animal, Departamento de Biología, Facultad de Ciencias, Universidad de Los Andes, Mérida 5101, Venezuela. Electronic address:

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http://dx.doi.org/10.1016/j.molbiopara.2014.02.005DOI Listing
February 2014

Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.

ACS Med Chem Lett 2014 Jan 30;5(1):12-7. Epub 2013 Oct 30.

National Center for Advancing Translational Sciences, National Institutes of Health , 9800 Medical Center Drive, Rockville, Maryland 20850, United States.

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http://dx.doi.org/10.1021/ml400259dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027769PMC
January 2014

Ubiquitination of the glycosomal matrix protein receptor PEX5 in Trypanosoma brucei by PEX4 displays novel features.

Biochim Biophys Acta 2013 Dec 27;1833(12):3076-3092. Epub 2013 Aug 27.

Research Unit for Tropical Diseases, de Duve Institute, and Laboratory of Biochemistry, Université catholique de Louvain, Avenue Hippocrate 74, B-1200 Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2013.08.008DOI Listing
December 2013

`In crystallo' substrate binding triggers major domain movements and reveals magnesium as a co-activator of Trypanosoma brucei pyruvate kinase.

Acta Crystallogr D Biol Crystallogr 2013 Sep 17;69(Pt 9):1768-79. Epub 2013 Aug 17.

Centre for Translational and Chemical Biology, School of Biological Sciences, The University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, Scotland.

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http://dx.doi.org/10.1107/S0907444913013875DOI Listing
September 2013

Biochemical effects of riluzole on Leishmania parasites.

Exp Parasitol 2013 Mar 1;133(3):250-4. Epub 2012 Dec 1.

Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Via Campi 183, 41100 Modena, Italy.

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http://dx.doi.org/10.1016/j.exppara.2012.11.013DOI Listing
March 2013

Processing of the glycosomal matrix-protein import receptor PEX5 of Trypanosoma brucei.

Biochem Biophys Res Commun 2013 Feb 22;431(1):98-103. Epub 2012 Dec 22.

Research Unit for Tropical Diseases, de Duve Institute, Université catholique de Louvain, Brussels, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X120242
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http://dx.doi.org/10.1016/j.bbrc.2012.12.075DOI Listing
February 2013

Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities and limitations for targeting with trypanocidal drugs.

Parasitology 2013 Jan 23;140(1):1-20. Epub 2012 Aug 23.

Research Unit for Tropical Diseases, de Duve Institute, Université Catholique de Louvain, Avenue Hippocrate 74, Postal Box B1.74.01, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1017/S0031182012001278DOI Listing
January 2013

Fumarate hydratase isoforms of Leishmania major: subcellular localization, structural and kinetic properties.

Int J Biol Macromol 2012 Jul-Aug;51(1-2):25-31. Epub 2012 May 5.

Laboratório de Cristalografia de Proteínas, FCFRP, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil.

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http://dx.doi.org/10.1016/j.ijbiomac.2012.04.025DOI Listing
October 2012

Studies on the organization of the docking complex involved in matrix protein import into glycosomes of Trypanosoma brucei.

Biochem Biophys Res Commun 2012 Aug 16;424(4):781-5. Epub 2012 Jul 16.

Research Unit for Tropical Diseases, de Duve Institute, Laboratory of Biochemistry, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.bbrc.2012.07.035DOI Listing
August 2012

Autophagy in trypanosomatids.

Cells 2012 Jul 27;1(3):346-71. Epub 2012 Jul 27.

Research Unit for Tropical Diseases, de Duve Institute, Université catholique de Louvain, Avenue Hippocrate 74, postal box B1.74.01, B-1200 Brussels, Belgium.

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http://www.mdpi.com/2073-4409/1/3/346
Publisher Site
http://dx.doi.org/10.3390/cells1030346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901119PMC
July 2012

Structural role of the active-site metal in the conformation of Trypanosoma brucei phosphoglycerate mutase.

FEBS J 2012 Jun 24;279(11):2012-21. Epub 2012 Apr 24.

Instituto de Física de São Carlos, Grupo de Cristalografia, Universidade de São Paulo, São Carlos, São Paulo, Brazil.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08586.xDOI Listing
June 2012

Trypanosomes contain two highly different isoforms of peroxin PEX13 involved in glycosome biogenesis.

FEBS Lett 2012 Jun 26;586(13):1765-71. Epub 2012 May 26.

Research Unit for Tropical Diseases, de Duve Institute and Laboratory of Biochemistry, Université catholique de Louvain, Avenue Hippocrate 74, Postal Box B1.74.01, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.febslet.2012.05.019DOI Listing
June 2012

Extra-glycosomal localisation of Trypanosoma brucei hexokinase 2.

Int J Parasitol 2012 Apr;42(4):401-9

Department of Genetics and Biochemistry, Clemson University, Clemson, SC 39634, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710734PMC
http://dx.doi.org/10.1016/j.ijpara.2012.02.008DOI Listing
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V 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Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan 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Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

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Crystal structures of Leishmania mexicana phosphoglycerate mutase suggest a one-metal mechanism and a new enzyme subclass.

J Mol Biol 2009 Dec 23;394(3):535-43. Epub 2009 Sep 23.

Structural Biochemistry Group, Institute of Structural and Molecular Biology, University of Edinburgh, King's Buildings, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.jmb.2009.09.041DOI Listing
December 2009

Autophagy in protists: Examples of secondary loss, lineage-specific innovations, and the conundrum of remodeling a single mitochondrion.

Autophagy 2009 Aug 24;5(6):784-94. Epub 2009 Aug 24.

School of Biological Sciences, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.4161/auto.8838DOI Listing
August 2009

Identification, characterization and essentiality of the unusual peroxin 13 from Trypanosoma brucei.

Biochim Biophys Acta 2009 Mar 6;1793(3):516-27. Epub 2009 Jan 6.

Research Unit for Tropical Diseases, de Duve Institute, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.bbamcr.2008.12.020DOI Listing
March 2009

Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites.

Bioorg Med Chem 2009 Mar 4;17(6):2483-9. Epub 2009 Feb 4.

Centro de Biologia Molecular Estrutural, Instituto de Física de São Carlos, Universidade de São Paulo, Av. Trabalhador São Carlense 400, São Carlos, Brazil.

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http://dx.doi.org/10.1016/j.bmc.2009.01.068DOI Listing
March 2009

The crystal structure of ATP-bound phosphofructokinase from Trypanosoma brucei reveals conformational transitions different from those of other phosphofructokinases.

J Mol Biol 2009 Feb 3;385(5):1519-33. Epub 2008 Dec 3.

Structural Biochemistry Group, Institute of Structural and Molecular Biology, University of Edinburgh, King's Buildings, Edinburgh, Scotland.

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http://dx.doi.org/10.1016/j.jmb.2008.11.047DOI Listing
February 2009

Sulphate removal induces a major conformational change in Leishmania mexicana pyruvate kinase in the crystalline state.

J Mol Biol 2008 Nov 23;383(3):615-26. Epub 2008 Aug 23.

Institute of Structural and Molecular Biology, The University of Edinburgh, Michael Swann Building, The King's Buildings, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.jmb.2008.08.037DOI Listing
November 2008

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes.

Proc Natl Acad Sci U S A 2008 Nov 13;105(46):17718-23. Epub 2008 Nov 13.

Department of Molecular Cell Physiology, Faculty of Earth and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, NL-1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0806664105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584722PMC
November 2008

Structural insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.

J Mol Biol 2008 Sep 21;381(4):867-80. Epub 2008 Jun 21.

Department of Biochemistry, Biomolecular Structure Center, University of Washington, Box 357742, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.jmb.2008.05.089DOI Listing
September 2008

Complex I of Trypanosomatidae: does it exist?

Trends Parasitol 2008 Jul 3;24(7):310-7. Epub 2008 Jun 3.

de Duve Institute and Université catholique de Louvain, Avenue Hippocrate 74, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.pt.2008.03.013DOI Listing
July 2008

Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis.

Bioorg Med Chem 2008 May 21;16(9):5050-61. Epub 2008 Mar 21.

School of Chemistry, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, EH9 3JJ, UK.

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http://dx.doi.org/10.1016/j.bmc.2008.03.045DOI Listing
May 2008

Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei.

Mol Biochem Parasitol 2008 Apr 23;158(2):189-201. Epub 2007 Dec 23.

Hormone Research Unit, de Duve Institute, Université catholique de Louvain, Avenue Hippocrate 75, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.molbiopara.2007.12.008DOI Listing
April 2008

Turnover of glycosomes during life-cycle differentiation of Trypanosoma brucei.

Autophagy 2008 Apr;4(3):294-308

Research Unit for Tropical Diseases; de Duve Institute; Brussels, Belgium.

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http://dx.doi.org/10.4161/auto.5443DOI Listing
April 2008

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.

Authors:
Daniel J Klionsky Hagai Abeliovich Patrizia Agostinis Devendra K Agrawal Gjumrakch Aliev David S Askew Misuzu Baba Eric H Baehrecke Ben A Bahr Andrea Ballabio Bruce A Bamber Diane C Bassham Ettore Bergamini Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Dale E Bredesen Jeffrey L Brodsky John H Brumell Ulf T Brunk Wilfried Bursch Nadine Camougrand Eduardo Cebollero Francesco Cecconi Yingyu Chen Lih-Shen Chin Augustine Choi Charleen T Chu Jongkyeong Chung Peter G H Clarke Robert S B Clark Steven G Clarke Corinne Clavé John L Cleveland Patrice Codogno María I Colombo Ana Coto-Montes James M Cregg Ana Maria Cuervo Jayanta Debnath Francesca Demarchi Patrick B Dennis Phillip A Dennis Vojo Deretic Rodney J Devenish Federica Di Sano J Fred Dice Marian Difiglia Savithramma Dinesh-Kumar Clark W Distelhorst Mojgan Djavaheri-Mergny Frank C Dorsey Wulf Dröge Michel Dron William A Dunn Michael Duszenko N Tony Eissa Zvulun Elazar Audrey Esclatine Eeva-Liisa Eskelinen László Fésüs Kim D Finley José M Fuentes Juan Fueyo Kozo Fujisaki Brigitte Galliot Fen-Biao Gao David A Gewirtz Spencer B Gibson Antje Gohla Alfred L Goldberg Ramon Gonzalez Cristina González-Estévez Sharon Gorski Roberta A Gottlieb Dieter Häussinger You-Wen He Kim Heidenreich Joseph A Hill Maria Høyer-Hansen Xun Hu Wei-Pang Huang Akiko Iwasaki Marja Jäättelä William T Jackson Xuejun Jiang Shengkan Jin Terje Johansen Jae U Jung Motoni Kadowaki Chanhee Kang Ameeta Kelekar David H Kessel Jan A K W Kiel Hong Pyo Kim Adi Kimchi Timothy J Kinsella Kirill Kiselyov Katsuhiko Kitamoto Erwin Knecht Masaaki Komatsu Eiki Kominami Seiji Kondo Attila L Kovács Guido Kroemer Chia-Yi Kuan Rakesh Kumar Mondira Kundu Jacques Landry Marianne Laporte Weidong Le Huan-Yao Lei Michael J Lenardo Beth Levine Andrew Lieberman Kah-Leong Lim Fu-Cheng Lin Willisa Liou Leroy F Liu Gabriel Lopez-Berestein Carlos López-Otín Bo Lu Kay F Macleod Walter Malorni Wim Martinet Ken Matsuoka Josef Mautner Alfred J Meijer Alicia Meléndez Paul Michels Giovanni Miotto Wilhelm P Mistiaen Noboru Mizushima Baharia Mograbi Iryna Monastyrska Michael N Moore Paula I Moreira Yuji Moriyasu Tomasz Motyl Christian Münz Leon O Murphy Naweed I Naqvi Thomas P Neufeld Ichizo Nishino Ralph A Nixon Takeshi Noda Bernd Nürnberg Michinaga Ogawa Nancy L Oleinick Laura J Olsen Bulent Ozpolat Shoshana Paglin Glen E Palmer Issidora Papassideri Miles Parkes David H Perlmutter George Perry Mauro Piacentini Ronit Pinkas-Kramarski Mark Prescott Tassula Proikas-Cezanne Nina Raben Abdelhaq Rami Fulvio Reggiori Bärbel Rohrer David C Rubinsztein Kevin M Ryan Junichi Sadoshima Hiroshi Sakagami Yasuyoshi Sakai Marco Sandri Chihiro Sasakawa Miklós Sass Claudio Schneider Per O Seglen Oleksandr Seleverstov Jeffrey Settleman John J Shacka Irving M Shapiro Andrei Sibirny Elaine C M Silva-Zacarin Hans-Uwe Simon Cristiano Simone Anne Simonsen Mark A Smith Katharina Spanel-Borowski Vickram Srinivas Meredith Steeves Harald Stenmark Per E Stromhaug Carlos S Subauste Seiichiro Sugimoto David Sulzer Toshihiko Suzuki Michele S Swanson Ira Tabas Fumihiko Takeshita Nicholas J Talbot Zsolt Tallóczy Keiji Tanaka Kozo Tanaka Isei Tanida Graham S Taylor J Paul Taylor Alexei Terman Gianluca Tettamanti Craig B Thompson Michael Thumm Aviva M Tolkovsky Sharon A Tooze Ray Truant Lesya V Tumanovska Yasuo Uchiyama Takashi Ueno Néstor L Uzcátegui Ida van der Klei Eva C Vaquero Tibor Vellai Michael W Vogel Hong-Gang Wang Paul Webster John W Wiley Zhijun Xi Gutian Xiao Joachim Yahalom Jin-Ming Yang George Yap Xiao-Ming Yin Tamotsu Yoshimori Li Yu Zhenyu Yue Michisuke Yuzaki Olga Zabirnyk Xiaoxiang Zheng Xiongwei Zhu Russell L Deter

Autophagy 2008 Feb 21;4(2):151-75. Epub 2007 Nov 21.

Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109-2216, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654259PMC
http://dx.doi.org/10.4161/auto.5338DOI Listing
February 2008

Molecular and biochemical characterization of novel glucokinases from Trypanosoma cruzi and Leishmania spp.

Mol Biochem Parasitol 2007 Dec 26;156(2):235-45. Epub 2007 Aug 26.

Unidad de Bioquímica de Parásitos, Centro de Ingeniería Genética, Facultad de Ciencias, Universidad de Los Andes, Mérida 5101, Venezuela.

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http://dx.doi.org/10.1016/j.molbiopara.2007.08.007DOI Listing
December 2007

The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes.

J Mol Biol 2007 Oct 26;372(5):1215-26. Epub 2007 Jul 26.

Research Unit for Tropical Diseases, Christian de Duve Institute of Cellular Pathology, Avenue Hippocrate 74, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.jmb.2007.07.021DOI Listing
October 2007

Horizontal gene transfer in trypanosomatids.

Trends Parasitol 2007 Oct 7;23(10):470-6. Epub 2007 Sep 7.

Research Unit for Tropical Diseases, Christian de Duve Institute of Cellular Pathology and Laboratory of Biochemistry, Université catholique de Louvain, Avenue Hippocrate 74-75, B-1200 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.pt.2007.08.002DOI Listing
October 2007

Leishmania mexicana: molecular cloning and characterization of enolase.

Exp Parasitol 2007 Jul 23;116(3):241-51. Epub 2007 Jan 23.

Laboratorio de Enzimología de Parásitos, Facultad de Ciencias, Universidad de Los Andes, Apartado Postal 38, Ipostel-La hechicera, Mérida, Venezuela.

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http://dx.doi.org/10.1016/j.exppara.2007.01.008DOI Listing
July 2007

Characterization of the role of the receptors PEX5 and PEX7 in the import of proteins into glycosomes of Trypanosoma brucei.

Biochim Biophys Acta 2007 Apr 20;1773(4):521-35. Epub 2007 Jan 20.

Research Unit for Tropical Diseases, Christian de Duve Institute of Cellular Pathology and Laboratory of Biochemistry, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.bbamcr.2007.01.006DOI Listing
April 2007

The first crystal structure of phosphofructokinase from a eukaryote: Trypanosoma brucei.

J Mol Biol 2007 Mar 11;366(4):1185-98. Epub 2006 Oct 11.

Structural Biochemistry Group, Institute of Structural and Molecular Biology, University of Edinburgh, King's Buildings, Edinburgh EH9 3JR, Scotland.

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http://dx.doi.org/10.1016/j.jmb.2006.10.019DOI Listing
March 2007