Paul Matejtschuk

Paul Matejtschuk

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Paul Matejtschuk

Paul Matejtschuk

Publications by authors named "Paul Matejtschuk"

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25Publications

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The influence of the closure format on the storage stability and moisture content of freeze-dried influenza antigen.

Vaccine 2019 Jul 2. Epub 2019 Jul 2.

Surfaces and Particle Engineering Laboratory, Department of Chemical Engineering, Imperial College London, SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1016/j.vaccine.2019.06.070DOI Listing
July 2019

Measuring the Specific Surface Area (SSA) of Freeze-Dried Biologics using Inverse Gas Chromatography.

Eur J Pharm Biopharm 2019 Jun 21. Epub 2019 Jun 21.

Surfaces and Particle Engineering Laboratory, Department of Chemical Engineering, Imperial College London, SW7 2AZ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2019.06.026DOI Listing
June 2019

Development of a stable chemically cross-linked erythropoietin dimer for use in the quality control of erythropoietin therapeutic products.

Anal Bioanal Chem 2019 May 10;411(13):2755-2758. Epub 2019 Apr 10.

National Institute for Biological Standards & Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.

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http://dx.doi.org/10.1007/s00216-019-01768-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522647PMC
May 2019

Vacuum-Induced Surface Freezing for the Freeze-Drying of the Human Growth Hormone: How Does Nucleation Control Affect Protein Stability?

J Pharm Sci 2019 Apr 17. Epub 2019 Apr 17.

Standardisation Science Section, Analytical and Biological Sciences Division, National Institute for Biological Standards and Control, Blanche Lane, Medicines & Healthcare Products Agency, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2019.04.014DOI Listing
April 2019

Selective Stabilization and Destabilization of Protein Domains in Tissue-Type Plasminogen Activator Using Formulation Excipients.

Mol Pharm 2019 02 9;16(2):744-755. Epub 2019 Jan 9.

Department of Biochemical Engineering , University College London , Gower Street , London WC1E 6BT , U.K.

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http://pubs.acs.org/doi/10.1021/acs.molpharmaceut.8b01024
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http://dx.doi.org/10.1021/acs.molpharmaceut.8b01024DOI Listing
February 2019

Quantification of Müllerian Inhibiting Substance/Anti-Müllerian Hormone polypeptide by isotope dilution mass spectrometry.

Anal Biochem 2018 Nov 6;560:50-55. Epub 2018 May 6.

National Institute for Biological Standards and Control, South Mimms, Potters Bar, EN6 3QG, UK.

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http://dx.doi.org/10.1016/j.ab.2018.05.006DOI Listing
November 2018

Towards international standardization of immunoassays for Müllerian inhibiting substance/anti-Müllerian hormone.

Reprod Biomed Online 2018 Nov 5;37(5):631-640. Epub 2018 Sep 5.

Biotherapeutics Division, NIBSC, South Mimms, Potters Bar Hertfordshire, UK.

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http://dx.doi.org/10.1016/j.rbmo.2018.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302068PMC
November 2018

Humidity induced collapse in freeze dried cakes: A direct visualization study using DVS.

Eur J Pharm Biopharm 2018 Jun 3;127:29-36. Epub 2018 Feb 3.

Surfaces and Particle Engineering Laboratory, Department of Chemical Engineering, Imperial College London, SW7 2AZ, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09396411173131
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http://dx.doi.org/10.1016/j.ejpb.2018.02.003DOI Listing
June 2018

T-Values and Unfolded Fraction Can Predict Aggregation Rates for Granulocyte Colony Stimulating Factor Variant Formulations but Not under Predominantly Native Conditions.

Mol Pharm 2018 01 28;15(1):256-267. Epub 2017 Nov 28.

Department of Biochemical Engineering, University College London , London WC1E 7JE, U.K.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00876DOI Listing
January 2018

The importance of formulation in the successful lyophilization of influenza reference materials.

Biologicals 2015 Mar 20;43(2):110-6. Epub 2015 Jan 20.

Standardisation Science, NIBSC, Medicines & Healthcare Products Regulatory Agency, Blanche Lane, South Mimms, Potters Bar, EN6 3QG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.biologicals.2014.12.001DOI Listing
March 2015

Differential scanning fluorimetry: rapid screening of formulations that promote the stability of reference preparations.

J Pharm Biomed Anal 2013 Apr 8;77:163-6. Epub 2013 Jan 8.

Standardisation Science, National Institute for Biological Standards and Control, Health Protection Agency, South Mimms, Potters Bar Herts, UK.

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http://dx.doi.org/10.1016/j.jpba.2013.01.006DOI Listing
April 2013

Freeze drying formulation using microscale and design of experiment approaches: a case study using granulocyte colony-stimulating factor.

Biotechnol Lett 2012 Apr 21;34(4):641-8. Epub 2011 Dec 21.

Department of Biochemical Engineering, The Advanced Centre for Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK.

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http://dx.doi.org/10.1007/s10529-011-0822-2DOI Listing
April 2012

The first international standard for antibodies to HPV 16.

Vaccine 2011 Sep 19;29(38):6520-6. Epub 2011 Jul 19.

Division of Virology, National Institute for Biological Standards and Control, Health Protection Agency, Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, UK.

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http://dx.doi.org/10.1016/j.vaccine.2011.07.007DOI Listing
September 2011

The 2nd International Standard for human granulocyte colony stimulating factor.

J Immunol Methods 2011 Mar 17;367(1-2):63-9. Epub 2011 Feb 17.

Biotherapeutics Group, NIBSC, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S002217591100037
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http://dx.doi.org/10.1016/j.jim.2011.02.005DOI Listing
March 2011

Release of proteolytic activity following reduction in therapeutic human serum albumin containing products: detection with a new neoepitope endopeptidase immunoassay.

J Pharm Biomed Anal 2011 Jan 19;54(1):74-80. Epub 2010 Aug 19.

National Institute for Biological Standards and Control, Health Protection Agency, Division of Bacteriology, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S07317085100047
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http://dx.doi.org/10.1016/j.jpba.2010.08.013DOI Listing
January 2011

Collaborative study for the calibration of a replacement international standard for diphtheria toxoid adsorbed.

Biologicals 2010 Sep 19;38(5):529-38. Epub 2010 Jun 19.

Division of Bacteriology, National Institute for Biological Standards and Control, Health Protection Agency, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, United Kingdom.

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http://dx.doi.org/10.1016/j.biologicals.2010.04.001DOI Listing
September 2010

Use of dynamic mechanical analysis (DMA) to determine critical transition temperatures in frozen biomaterials intended for lyophilization.

Cryobiology 2010 Aug 27;61(1):27-32. Epub 2010 Apr 27.

Gearing Scientific Ltd., 4 Springhead, Ashwell, Hertfordshire, SG7 5LL, United Kingdom.

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http://dx.doi.org/10.1016/j.cryobiol.2010.04.002DOI Listing
August 2010

Rapid optimization of protein freeze-drying formulations using ultra scale-down and factorial design of experiment in microplates.

Biotechnol Bioeng 2009 Dec;104(5):957-64

Department of Biochemical Engineering, The Advanced Centre for Biochemical Engineering, University College London, Torrington Place, London WC1E 7JE, UK.

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http://doi.wiley.com/10.1002/bit.22448
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http://dx.doi.org/10.1002/bit.22448DOI Listing
December 2009

Lyophilization of biological standards.

Authors:
Paul Matejtschuk

Cryo Letters 2005 Jul-Aug;26(4):223-30

Centre for Biological Reference Materials, National Institute for Biological Standards & Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK.

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November 2009

Lyophilization of proteins.

Authors:
Paul Matejtschuk

Methods Mol Biol 2007 ;368:59-72

Standardization Science, National Institute of Biological Standards and Control, Potters Bar, Hertfordshire, UK.

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http://dx.doi.org/10.1007/978-1-59745-362-2_4DOI Listing
July 2008

Impact of residual moisture and formulation on Factor VIII and Factor V recovery in lyophilized plasma reference materials.

Anal Bioanal Chem 2007 Apr 27;387(7):2503-7. Epub 2006 Oct 27.

National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.

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http://link.springer.com/10.1007/s00216-006-0855-x
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http://dx.doi.org/10.1007/s00216-006-0855-xDOI Listing
April 2007

A comparison of vials with ampoules for the storage of biological reference materials.

Biologicals 2005 Jun;33(2):63-70

National Institute for Biological Standards & Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK.

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http://dx.doi.org/10.1016/j.biologicals.2004.12.002DOI Listing
June 2005

Thiophilic affinity chromatography and related methods.

Authors:
Paul Matejtschuk

Methods Mol Biol 2004 ;244:195-204

National Institute for Biological Standards and Control, South Mimms, Potters Bar, UK.

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April 2004