Paul M Matthews

Paul M Matthews

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Chronic inflammation in multiple sclerosis - seeing what was always there.

Authors:
Paul M Matthews

Nat Rev Neurol 2019 Oct 16;15(10):582-593. Epub 2019 Aug 16.

Department of Brain Sciences, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/s41582-019-0240-yDOI Listing
October 2019

Evaluation of multiple sclerosis disability outcome measures using pooled clinical trial data.

Neurology 2019 Oct 22. Epub 2019 Oct 22.

From the University of Virginia (M.D.G.), Charlottesville; National Multiple Sclerosis Society (N.G.L.), New York, NY; Biogen (R.A.R., G.P.), Cambridge, MA; Critical Path Institute (L.D.H.), Tucson, AZ; Genentech (P.S.C.), South San Francisco, CA; Independent Neurology Clinical Development Consultant (G.S.F.); Premier Research (A.J.), Wokingham, UK; UCL Institute of Neurology (R.K.), London, UK; Imperial College London and UK Dementia Research Institute (P.M.M.); Johns Hopkins (E.M.M.), Baltimore, MD; New York University School of Medicine (L.J.B.), NY; Wave Life Sciences (M.P.), Cambridge, MA; VU University Medical Center (B.M.J.U.), Amsterdam, the Netherlands; and Cleveland Clinic (J.A.C.), OH.

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http://dx.doi.org/10.1212/WNL.0000000000008519DOI Listing
October 2019

Towards a standard MRI protocol for multiple sclerosis across the UK.

Br J Radiol 2019 Sep 14;92(1101):20180926. Epub 2019 May 14.

7Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany.

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https://www.birpublications.org/doi/10.1259/bjr.20180926
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http://dx.doi.org/10.1259/bjr.20180926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732926PMC
September 2019

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.

Authors:
Evangelos Evangelou He Gao Congying Chu Georgios Ntritsos Paul Blakeley Andrew R Butts Raha Pazoki Hideaki Suzuki Fotios Koskeridis Andrianos M Yiorkas Ibrahim Karaman Joshua Elliott Qiang Luo Stefanie Aeschbacher Traci M Bartz Sebastian E Baumeister Peter S Braund Michael R Brown Jennifer A Brody Toni-Kim Clarke Niki Dimou Jessica D Faul Georg Homuth Anne U Jackson Katherine A Kentistou Peter K Joshi Rozenn N Lemaitre Penelope A Lind Leo-Pekka Lyytikäinen Massimo Mangino Yuri Milaneschi Christopher P Nelson Ilja M Nolte Mia-Maria Perälä Ozren Polasek David Porteous Scott M Ratliff Jennifer A Smith Alena Stančáková Alexander Teumer Samuli Tuominen Sébastien Thériault Jagadish Vangipurapu John B Whitfield Alexis Wood Jie Yao Bing Yu Wei Zhao Dan E Arking Juha Auvinen Chunyu Liu Minna Männikkö Lorenz Risch Jerome I Rotter Harold Snieder Juha Veijola Alexandra I Blakemore Michael Boehnke Harry Campbell David Conen Johan G Eriksson Hans J Grabe Xiuqing Guo Pim van der Harst Catharina A Hartman Caroline Hayward Andrew C Heath Marjo-Riitta Jarvelin Mika Kähönen Sharon L R Kardia Michael Kühne Johanna Kuusisto Markku Laakso Jari Lahti Terho Lehtimäki Andrew M McIntosh Karen L Mohlke Alanna C Morrison Nicholas G Martin Albertine J Oldehinkel Brenda W J H Penninx Bruce M Psaty Olli T Raitakari Igor Rudan Nilesh J Samani Laura J Scott Tim D Spector Niek Verweij David R Weir James F Wilson Daniel Levy Ioanna Tzoulaki Jimmy D Bell Paul M Matthews Adrian Rothenfluh Sylvane Desrivières Gunter Schumann Paul Elliott

Nat Hum Behav 2019 Sep 29;3(9):950-961. Epub 2019 Jul 29.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/s41562-019-0653-zDOI Listing
September 2019

Breaking the cycle: Reversal of flux in the tricarboxylic acid cycle by dimethyl fumarate.

Neurol Neuroimmunol Neuroinflamm 2019 May 22;6(3):e562. Epub 2019 Apr 22.

Division of Brain Sciences (T.T., R.N., P.M.M.), Department of Medicine, Imperial College, London; St Edmund Hall (C.S., P.M.M.), Oxford University, Oxford, UK; MRC-NIHR National Phenome Centre (M.D., M.G.-R., M.R.L.), Department of Surgery and Cancer, Imperial College; University College London Queen Square Institute of Neurology (A.H., H.Z.); UK Dementia Research Institute, University College London (A.H., H.Z.), London, UK; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, the University of Gothenburg; Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden; and UK Dementia Research Institute at Imperial College (P.M.M.), London.

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http://dx.doi.org/10.1212/NXI.0000000000000562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481230PMC
May 2019

Anti-TNF modulation reduces myocardial inflammation and improves cardiovascular function in systemic rheumatic diseases.

Int J Cardiol 2018 Nov 25;270:253-259. Epub 2018 Jun 25.

University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, Oxford, UK; First Department of Cardiology, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.06.099DOI Listing
November 2018

Distinguishable brain networks relate disease susceptibility to symptom expression in schizophrenia.

Hum Brain Mapp 2018 09 24;39(9):3503-3515. Epub 2018 Apr 24.

Mental Health Center and Psychiatric Laboratory, The State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, People's Republic of China.

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http://dx.doi.org/10.1002/hbm.24190DOI Listing
September 2018

Remote Monitoring in the Home Validates Clinical Gait Measures for Multiple Sclerosis.

Front Neurol 2018 13;9:561. Epub 2018 Jul 13.

Data Science Institute, Imperial College London London, United Kingdom.

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http://dx.doi.org/10.3389/fneur.2018.00561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053510PMC
July 2018

Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS.

Neurol Neuroimmunol Neuroinflamm 2018 Jul 12;5(4):e470. Epub 2018 Jun 12.

Division of Brain Sciences (A.R.G., M.T.C., R.N.), Department of Medicine, Imperial College London; the Department of Neurology (K.K.), Weill Institute for Neurosciences, University of California, San Francisco; icometrix (W.v.H.), Begaultlaan, Leuven, Belgium; the Department of Neurology (S.E.B.), Weill Institute for Neurosciences, Institute for Human Genetics and Graduate Program in Bioinformatics, University of California, San Francisco; and Division of Brain Sciences (P.M.M.), Department of Medicine, the Centre for Neurotechnology and the UK Dementia Research Institute, Imperial College London.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168332PMC
July 2018

Mixed Neural Network Approach for Temporal Sleep Stage Classification.

IEEE Trans Neural Syst Rehabil Eng 2018 02 28;26(2):324-333. Epub 2017 Jul 28.

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http://dx.doi.org/10.1109/TNSRE.2017.2733220DOI Listing
February 2018

Cardiovascular magnetic resonance characterization of myocardial and vascular function in rheumatoid arthritis patients.

Hellenic J Cardiol 2019 Jan - Feb;60(1):28-35. Epub 2018 Jan 31.

University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK; First Department of Cardiology, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S11099666173049
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http://dx.doi.org/10.1016/j.hjc.2018.01.008DOI Listing
January 2018

Abnormal brain white matter microstructure is associated with both pre-hypertension and hypertension.

PLoS One 2017 16;12(11):e0187600. Epub 2017 Nov 16.

Division of Brain Sciences, Department of Medicine, Hammersmith Hospital, Imperial College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187600PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690584PMC
December 2017

Achievements and obstacles of remyelinating therapies in multiple sclerosis.

Nat Rev Neurol 2017 Dec 17;13(12):742-754. Epub 2017 Nov 17.

Department of Anatomy and Neuroscience and Melbourne Neuroscience Institute, University of Melbourne, 30 Royal Parade, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1038/nrneurol.2017.139DOI Listing
December 2017

Advanced MRI measures like DTI or fMRI should be outcome measures in future clinical trials - NO.

Authors:
Paul M Matthews

Mult Scler 2017 10 30;23(11):1456-1458. Epub 2017 Jun 30.

Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, London, UK/Centre for Neurotechnology, Imperial College London, London, UK/UK Dementia Research Institute, Imperial College London, London, UK.

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http://dx.doi.org/10.1177/1352458517713345DOI Listing
October 2017

C-PBR28 and F-PBR111 Detect White Matter Inflammatory Heterogeneity in Multiple Sclerosis.

J Nucl Med 2017 09 16;58(9):1477-1482. Epub 2017 Mar 16.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom

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http://dx.doi.org/10.2967/jnumed.116.187161DOI Listing
September 2017

Improving data availability for brain image biobanking in healthy subjects: Practice-based suggestions from an international multidisciplinary working group.

Neuroimage 2017 06 14;153:399-409. Epub 2017 Feb 14.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK; Scottish Imaging Network, a Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh,UK; Department of Neuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, UK; Edinburgh Imaging, University of Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2017.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798604PMC
June 2017

Personalised medicine for multiple sclerosis care.

Mult Scler 2017 Mar 28;23(3):362-369. Epub 2016 Sep 28.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK/Centre for Neurotechnology, Imperial College London, London, UK.

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http://dx.doi.org/10.1177/1352458516672017DOI Listing
March 2017

tranSMART-XNAT Connector tranSMART-XNAT connector-image selection based on clinical phenotypes and genetic profiles.

Bioinformatics 2017 03;33(5):787-788

Data Science Institute, Imperial College London, London, UK.

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http://dx.doi.org/10.1093/bioinformatics/btw714DOI Listing
March 2017

Scanning the horizon: towards transparent and reproducible neuroimaging research.

Nat Rev Neurosci 2017 02 5;18(2):115-126. Epub 2017 Jan 5.

Department of Psychology, University of Texas at Austin, Austin, Texas 78712, USA.

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http://dx.doi.org/10.1038/nrn.2016.167DOI Listing
February 2017

Role of 18F-fluorodeoxyglucose Positron Emission Tomography in the Monitoring of Inflammatory Activity in Crohn's Disease.

Inflamm Bowel Dis 2016 11;22(11):2619-2629

*Division of Experimental Medicine, Department of Medicine, Imperial College London, London, United Kingdom; Departments of †Gastroenterology and ‡Imaging, Imperial College Healthcare NHS Trust, London, United Kingdom; §Imanova Centre for Imaging Sciences, London, United Kingdom; ‖Centre for Neuroimaging Sciences, King's College, London, United Kingdom; ¶Centre for Medical Imaging, University College London, London, United Kingdom; **Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom; and ††Division of Hepatology and Gastroenterology, Department of Surgery and Cancer, Imperial College Healthcare NHS Trust, London, United Kingdom.

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http://dx.doi.org/10.1097/MIB.0000000000000924DOI Listing
November 2016

A practical review of the neuropathology and neuroimaging of multiple sclerosis.

Pract Neurol 2016 Aug 23;16(4):279-87. Epub 2016 Mar 23.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/practneurol-2016-001381DOI Listing
August 2016

Clinical Concepts Emerging from fMRI Functional Connectomics.

Neuron 2016 Aug;91(3):511-28

Division of Brain Sciences, Department of Medicine and Centre for Neurotechnology, Imperial College London, London WC12 0NN, UK.

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http://dx.doi.org/10.1016/j.neuron.2016.07.031DOI Listing
August 2016

A new soft material based in-the-ear EEG recording technique.

Conf Proc IEEE Eng Med Biol Soc 2016 08;2016:5709-5712

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http://dx.doi.org/10.1109/EMBC.2016.7592023DOI Listing
August 2016

Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis.

Biol Psychiatry 2016 07 5;80(1):62-72. Epub 2015 Dec 5.

Psychological Medicine, and Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom; Imanova Centre for Imaging Sciences, London, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2015.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918731PMC
July 2016

A pilot study of the effect of short-term escitalopram treatment on brain metabolites and gamma-oscillations in healthy subjects.

J Psychopharmacol 2016 06;30(6):579-80

Faculty of Medicine, Division of Brain Sciences, Imperial College London, London, UK.

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http://dx.doi.org/10.1177/0269881116636108DOI Listing
June 2016

Kisspeptin signaling in the amygdala modulates reproductive hormone secretion.

Brain Struct Funct 2016 05 11;221(4):2035-47. Epub 2015 Mar 11.

Department of Investigative Medicine, Imperial College London, 6th Floor Commonwealth Building, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.

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http://dx.doi.org/10.1007/s00429-015-1024-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853463PMC
May 2016

Neuroinflammation in treated HIV-positive individuals: A TSPO PET study.

Neurology 2016 04 24;86(15):1425-1432. Epub 2016 Feb 24.

From the Division of Medicine, Section of Infectious Diseases (J.H.V., A.W.), Division of Brain Sciences (J.H.C., R.N.G., P.M.M.), and Centre for Immunology and Vaccinology (A.B., L.G., P.K.), Imperial College London; Division of Medicine (J.H.V.), Brighton and Sussex Medical School; Imanova Centre for Imaging Sciences (Q.G., E.A.R., N.K., C.B., R.N.G.), London; and Chelsea and Westminster Hospital (A.B., L.G., P.K.), London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000002485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831035PMC
April 2016

Design, Synthesis, and Evaluation of Fluorinated Radioligands for Myelin Imaging.

J Med Chem 2016 04 12;59(8):3705-18. Epub 2016 Apr 12.

Department of Anatomy and Regenerative Biology, George Washington University , Washington, DC 20037, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01858DOI Listing
April 2016

Amyloid pathology and axonal injury after brain trauma.

Neurology 2016 Mar 3;86(9):821-8. Epub 2016 Feb 3.

From the Division of Brain Sciences (G.S., A.F.R., P.E., P.H., J.C., R.L., S.M.G., R.A.H., P.M.M., D.J.B., D.J.S.), Department of Medicine, Imperial College London; Institute of Psychiatry, Psychology & Neuroscience (P.H., M.V., F.E.T.), King's College London; Institute of Neurology (R.J.G.), University College London, UK; MedTech West at Sahlgrenska University Hospital (R.A.H.), University of Gothenburg, Sweden; and Institute of Clinical Medicine (D.J.B.), Aarhus University, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000002413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793784PMC
March 2016

UK Biobank's cardiovascular magnetic resonance protocol.

J Cardiovasc Magn Reson 2016 Feb 1;18. Epub 2016 Feb 1.

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1186/s12968-016-0227-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736703PMC
February 2016

Professor Paul Matthews talks 'big data' within multiple sclerosis.

Authors:
Paul M Matthews

Neurodegener Dis Manag 2015 ;5(2):101-4

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http://dx.doi.org/10.2217/nmt.15.3DOI Listing
January 2016

The UK Biobank.

Brain 2015 Dec;138(Pt 12):3463-5

Centre for Clinical Brain Sciences, University of Edinburgh, and UK Biobank.

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http://dx.doi.org/10.1093/brain/awv335DOI Listing
December 2015

Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage.

J Neuroinflammation 2015 Dec 1;12:224. Epub 2015 Dec 1.

Division of Brain Sciences, Department of Medicine, Hammersmith Hospital Campus, Imperial College London, London, UK.

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http://dx.doi.org/10.1186/s12974-015-0445-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666189PMC
December 2015

Decade in review-multiple sclerosis: new drugs and personalized medicine for multiple sclerosis.

Authors:
Paul M Matthews

Nat Rev Neurol 2015 11 27;11(11):614-6. Epub 2015 Oct 27.

Division of Brain Sciences, Department of Medicine, Hammersmith Hospital, DuCane Road, London WC12 0NN.

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http://dx.doi.org/10.1038/nrneurol.2015.200DOI Listing
November 2015

Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele.

Alzheimers Dement 2015 Jun 23;11(6):648-57.e1. Epub 2014 Aug 23.

Department of Psychiatry, University of Oxford, Oxford United Kingdom; Functional Magnetic Resonance Imaging of the Brain Centre, University of Oxford, Oxford United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15525260140246
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http://dx.doi.org/10.1016/j.jalz.2014.05.1755DOI Listing
June 2015

Positron-emission tomography molecular imaging of glia and myelin in drug discovery for multiple sclerosis.

Expert Opin Drug Discov 2015 May 5;10(5):557-70. Epub 2015 Apr 5.

Imperial College London, Division of Brain Sciences, Department of Medicine , E515, Burlington Danes Building, Du Cane Road, W12 0NN London , UK +44 02075942612 ; +44 02075946548 ;

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http://dx.doi.org/10.1517/17460441.2015.1032240DOI Listing
May 2015

Diffuse Myocardial Fibrosis and Inflammation in Rheumatoid Arthritis: Insights From CMR T1 Mapping.

JACC Cardiovasc Imaging 2015 May 15;8(5):526-536. Epub 2015 Apr 15.

University of Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom; 1st Department of Cardiology, AHEPA Hospital, Aristotle University, Thessaloniki, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.jcmg.2014.12.025DOI Listing
May 2015

Bioenergetics and intermuscular fat in chronic obstructive pulmonary disease-associated quadriceps weakness.

Muscle Nerve 2015 Feb 19;51(2):214-21. Epub 2014 Nov 19.

Clinical Imaging Centre, GlaxoSmithKline Research and Development, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1002/mus.24289DOI Listing
February 2015

Relevance of parahippocampal-locus coeruleus connectivity to memory in early dementia.

Neurobiol Aging 2015 Feb 6;36(2):618-26. Epub 2014 Nov 6.

Division of Brain Sciences, Department of Medicine, Imperial College, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.10.041DOI Listing
February 2015

A common brain network links development, aging, and vulnerability to disease.

Proc Natl Acad Sci U S A 2014 Dec 24;111(49):17648-53. Epub 2014 Nov 24.

Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1410378111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267352PMC
December 2014

In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with (18)F-PBR111 PET.

J Nucl Med 2014 Jul 5;55(7):1112-8. Epub 2014 Jun 5.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom Neurosciences, GlaxoSmithKline, Brentford, United Kingdom

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http://dx.doi.org/10.2967/jnumed.113.135129DOI Listing
July 2014

Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study.

J Cereb Blood Flow Metab 2014 Jun 19;34(6):989-94. Epub 2014 Mar 19.

1] Centre for Neuroimaging Sciences, Institute of Psychiatry, King's College London, London, UK [2] Imanova, Centre for Imaging Sciences, London, UK.

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http://dx.doi.org/10.1038/jcbfm.2014.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050243PMC
June 2014

Automated identification of brain new lesions in multiple sclerosis using subtraction images.

J Magn Reson Imaging 2014 Jun;39(6):1543-9

Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.

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http://dx.doi.org/10.1002/jmri.24293DOI Listing
June 2014

The virtues of adaptability.

Authors:
Paul M Matthews

Mult Scler 2014 Apr;20(4):394-6

Division of Brain Sciences, Department of Medicine, Imperial College London, Burlington Danes, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1177/1352458513516690DOI Listing
April 2014

Subclinical myocardial inflammation and diffuse fibrosis are common in systemic sclerosis--a clinical study using myocardial T1-mapping and extracellular volume quantification.

J Cardiovasc Magn Reson 2014 Mar 4;16:21. Epub 2014 Mar 4.

Radcliffe Department of Medicine, Division of Cardiovascular Medicine, Level 0, John Radcliffe Hospital, University of Oxford Centre for Clinical Magnetic Resonance Research, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1186/1532-429X-16-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996013PMC
March 2014

Understanding the pharmacology of stroke and multiple sclerosis through imaging.

Curr Opin Pharmacol 2014 Feb 23;14:34-41. Epub 2013 Nov 23.

Division of Brain Sciences, Department of Medicine, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.coph.2013.10.006DOI Listing
February 2014

The emerging agenda of stratified medicine in neurology.

Nat Rev Neurol 2014 Jan 10;10(1):15-26. Epub 2013 Dec 10.

Department of Neurology, Charing Cross Hospital, St Dunstan's Road, London W6 8RP, UK.

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http://dx.doi.org/10.1038/nrneurol.2013.245DOI Listing
January 2014

Longitudinal positron emission tomography imaging for monitoring myelin repair in the spinal cord.

Ann Neurol 2013 Nov 23;74(5):688-98. Epub 2013 Sep 23.

Division of Radiopharmaceutical Science, Case Center for Imaging Research Department of Radiology, Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1002/ana.23965DOI Listing
November 2013

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO).

Psychoneuroendocrinology 2013 Nov 12;38(11):2826-9. Epub 2013 Aug 12.

Division of Brain Sciences, Imperial College, London, United Kingdom; Imanova Centre for Imaging Sciences, Hammersmith Hospital Campus, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2013.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820042PMC
November 2013

Neuroscience thinks big (and collaboratively).

Nat Rev Neurosci 2013 09;14(9):659-64

Columbia University, Department of Neuroscience, 1051 Riverside Drive, NYSPI-UNIT 25, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nrn3578DOI Listing
September 2013

Brain structural and functional connectivity and the progression of neuropathology in Alzheimer's disease.

J Alzheimers Dis 2013 ;33 Suppl 1:S163-72

Department of Medicine, Division of Brain Sciences, Imperial College, London, UK.

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http://dx.doi.org/10.3233/JAD-2012-129012DOI Listing
June 2013

A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers.

PLoS One 2012 20;7(12):e51395. Epub 2012 Dec 20.

The National Institute for Health Research-Wellcome Trust Imperial College Clinical Research Facility, Imperial Centre for Translational and Experimental Medicine, Imperial College London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051395PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527451PMC
June 2013

Imaging in population science: cardiovascular magnetic resonance in 100,000 participants of UK Biobank - rationale, challenges and approaches.

J Cardiovasc Magn Reson 2013 May 28;15:46. Epub 2013 May 28.

Centre Lead for Advanced Cardiovascular Imaging, William Harvey Research Institute, NIHR Cardiovascular Biomedical Research Unit at Barts, The London Chest Hospital, Bonner Road, London E2 9JX, UK.

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http://dx.doi.org/10.1186/1532-429X-15-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668194PMC
May 2013

A genome-wide association study of brain lesion distribution in multiple sclerosis.

Brain 2013 Apr 13;136(Pt 4):1012-24. Epub 2013 Feb 13.

Department of Neurology, School of Medicine, University of California, San Francisco, 675 Nelson Rising Lane, Suite 215, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1093/brain/aws363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613709PMC
April 2013

Glutamate gene polymorphisms predict brain volumes in multiple sclerosis.

Mult Scler 2013 Mar 31;19(3):281-8. Epub 2012 Jul 31.

Department of Neurology, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458512454345DOI Listing
March 2013

Histone deacetylase gene variants predict brain volume changes in multiple sclerosis.

Neurobiol Aging 2013 Jan 11;34(1):238-47. Epub 2012 Aug 11.

Department of Medicine, Centre for Neuroscience, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.07.007DOI Listing
January 2013

Relating brain damage to brain plasticity in patients with multiple sclerosis.

Neurorehabil Neural Repair 2012 Jul-Aug;26(6):581-93. Epub 2012 Feb 9.

Oxford Centre for Functional MRI of the Brain (FMRIB), University of Oxford, Oxford, UK.

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http://journals.sagepub.com/doi/10.1177/1545968311433208
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http://dx.doi.org/10.1177/1545968311433208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674542PMC
November 2012

The use of functional MRI to study appetite control in the CNS.

Exp Diabetes Res 2012 8;2012:764017. Epub 2012 May 8.

Division of Diabetes, Endocrinology and Metabolism, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1155/2012/764017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376546PMC
October 2012

Endogenous opioid release in the human brain reward system induced by acute amphetamine administration.

Biol Psychiatry 2012 Sep 3;72(5):371-7. Epub 2012 Mar 3.

Neuropsychopharmacology Unit, Centre for Pharmacology and Therapeutics, Division of Experimental Medicine, Department of Medicine, Imperial College, London, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2012.01.027DOI Listing
September 2012

Imaging brain microglial activation using positron emission tomography and translocator protein-specific radioligands.

Int Rev Neurobiol 2011 ;101:19-39

Division of Experimental Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.1016/B978-0-12-387718-5.00002-XDOI Listing
August 2012

T2* measurement of the knee articular cartilage in osteoarthritis at 3T.

J Magn Reson Imaging 2012 Jun 7;35(6):1422-9. Epub 2012 Feb 7.

GSK Clinical Imaging Centre, Hammersmith Hospital, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1002/jmri.23598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351813PMC
June 2012

Direct exposure of guinea pig CNS to human luteinizing hormone increases cerebrospinal fluid and cerebral beta amyloid levels.

Neuroendocrinology 2011 5;94(4):313-22. Epub 2011 Oct 5.

Centre of Excellence for Alzheimer's Disease Research and Care, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.

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http://dx.doi.org/10.1159/000330812DOI Listing
April 2012

Imaging the neuroendocrinology of appetite.

Adipocyte 2012 Jan;1(1):68-72

Section of Investigative Medicine; Division of Diabetes, Endocrinology and Metabolism; Imperial College London; London, UK.

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http://dx.doi.org/10.4161/adip.19021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661119PMC
January 2012