Paul M Brennan

Paul M Brennan

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Paul M Brennan

Paul M Brennan

Publications by authors named "Paul M Brennan"

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Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer.

Nat Commun 2019 Oct 8;10(1):4501. Epub 2019 Oct 8.

WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre, 99 George Street, Glasgow, G1 1RD, UK.

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http://dx.doi.org/10.1038/s41467-019-12527-5DOI Listing
October 2019

Developing infrared spectroscopic detection for stratifying brain tumour patients: glioblastoma multiforme vs. lymphoma.

Analyst 2019 Oct 15. Epub 2019 Oct 15.

WestCHEM, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George St, Glasgow, G1 1RD, UK. and ClinSpec Diagnostics, University of Strathclyde, Technology and Innovation Centre, 99 George Street, Glasgow, G1 1RD, UK.

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http://dx.doi.org/10.1039/c9an01731cDOI Listing
October 2019

The Relationship of the FOUR Score to Patient Outcome: A Systematic Review.

J Neurotrauma 2019 Sep 6;36(17):2469-2483. Epub 2019 Jun 6.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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https://www.liebertpub.com/doi/10.1089/neu.2018.6243
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http://dx.doi.org/10.1089/neu.2018.6243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709730PMC
September 2019

LINE-1 Evasion of Epigenetic Repression in Humans.

Mol Cell 2019 Aug 20;75(3):590-604.e12. Epub 2019 Jun 20.

Mater Research Institute, University of Queensland, TRI Building, Woolloongabba, QLD 4102, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765193039
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http://dx.doi.org/10.1016/j.molcel.2019.05.024DOI Listing
August 2019

Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma.

Neurosurg Rev 2019 Jun 21;42(2):427-431. Epub 2018 Apr 21.

Translational Neurosurgery, Centre for Clinical Brain Sciences, University of Edinburgh and Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1007/s10143-018-0979-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502770PMC
June 2019

Influence of Antiplatelet and Anticoagulant Drug Use on Outcomes after Chronic Subdural Hematoma Drainage.

J Neurotrauma 2019 Jan 30. Epub 2019 Jan 30.

1 Department of Clinical Neuroscience, Western General Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1089/neu.2018.6080DOI Listing
January 2019

Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices.

Chemistry 2018 Nov 8;24(63):16783-16790. Epub 2018 Nov 8.

Cancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.

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http://dx.doi.org/10.1002/chem.201803725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282958PMC
November 2018

Symptoms in primary care with time to diagnosis of brain tumours.

Fam Pract 2018 09;35(5):551-558

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/fampra/cmx139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142711PMC
September 2018

Simplifying the use of prognostic information in traumatic brain injury. Part 1: The GCS-Pupils score: an extended index of clinical severity.

J Neurosurg 2018 06 10;128(6):1612-1620. Epub 2018 Apr 10.

Institute of Health and Wellbeing, University of Glasgow, United Kingdom.

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http://dx.doi.org/10.3171/2017.12.JNS172780DOI Listing
June 2018

Simplifying the use of prognostic information in traumatic brain injury. Part 2: Graphical presentation of probabilities.

J Neurosurg 2018 06 10;128(6):1621-1634. Epub 2018 Apr 10.

3Institute of Health and Wellbeing, University of Glasgow, United Kingdom.

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http://dx.doi.org/10.3171/2017.12.JNS172782DOI Listing
June 2018

Residual enhancing disease after surgery for glioblastoma: evaluation of practice in the United Kingdom.

Neurooncol Pract 2018 May 27;5(2):74-81. Epub 2017 Sep 27.

Department of Neurosurgery, Addenbrookes Hospital, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.

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http://dx.doi.org/10.1093/nop/npx023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655490PMC
May 2018

Medically induced hypertension, hypervolaemia and haemodilution for the treatment and prophylaxis of vasospasm following aneurysmal subarachnoid haemorrhage: systematic review.

Br J Neurosurg 2018 Apr 17;32(2):157-164. Epub 2018 Jan 17.

c Department of Clinical Neurosciences , Western General Hospital , Edinburgh , UK.

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http://dx.doi.org/10.1080/02688697.2018.1426720DOI Listing
April 2018

A simple and robust real-time qPCR method for the detection of PIK3CA mutations.

Sci Rep 2018 03 9;8(1):4290. Epub 2018 Mar 9.

Institute of Biological Chemistry, Biophysics and Bioengineering, Heriot-Watt University, Edinburgh, EH14 4AS, UK.

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http://dx.doi.org/10.1038/s41598-018-22473-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844869PMC
March 2018

The British Neurosurgical Trainee Research Collaborative: Five years on.

Acta Neurochir (Wien) 2018 Jan 4;160(1):23-28. Epub 2017 Nov 4.

Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.1007/s00701-017-3351-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735202PMC
January 2018

Pre-operative obesity does not predict poorer symptom control and quality of life after lumbar disc surgery.

Br J Neurosurg 2017 Dec 19;31(6):682-687. Epub 2017 Jul 19.

b Department of Neurosurgery , Aberdeen Royal Infirmary , Aberdeen , UK.

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http://dx.doi.org/10.1080/02688697.2017.1354122DOI Listing
December 2017

Gold-Triggered Uncaging Chemistry in Living Systems.

Angew Chem Int Ed Engl 2017 10 9;56(41):12548-12552. Epub 2017 Aug 9.

Cancer Research (UK) Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.

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http://dx.doi.org/10.1002/anie.201705609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655737PMC
October 2017

Does a 3D Image Improve Laparoscopic Motor Skills?

J Laparoendosc Adv Surg Tech A 2016 Aug 7;26(8):671-3. Epub 2016 Jul 7.

1 Alder Hey Children's Hospital , Liverpool, United Kingdom .

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http://dx.doi.org/10.1089/lap.2016.0208DOI Listing
August 2016

Lack of Standardization in the Use of the Glasgow Coma Scale: Results of International Surveys.

J Neurotrauma 2016 Jan 12;33(1):89-94. Epub 2015 Aug 12.

3 Emeritus Professor of Neurosurgery, University of Glasgow , Glasgow, United Kingdom .

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http://dx.doi.org/10.1089/neu.2014.3843DOI Listing
January 2016

Ubiquitous L1 mosaicism in hippocampal neurons.

Cell 2015 Apr;161(2):228-39

Mater Research Institute - University of Queensland, TRI Building, Woolloongabba QLD 4102, Australia; Queensland Brain Institute, University of Queensland, Brisbane QLD 4072, Australia. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(15)00313-X.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S009286741500313
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http://dx.doi.org/10.1016/j.cell.2015.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398972PMC
April 2015

Accessible laparoscopic instrument tracking ("InsTrac"): construct validity in a take-home box simulator.

J Laparoendosc Adv Surg Tech A 2014 Aug;24(8):578-83

1 Royal Hospital for Sick Children , Edinburgh, Scotland, United Kingdom .

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http://dx.doi.org/10.1089/lap.2014.0015DOI Listing
August 2014

Patterning human neuronal networks on photolithographically engineered silicon dioxide substrates functionalized with glial analogues.

J Biomed Mater Res A 2014 May 11;102(5):1350-60. Epub 2013 Jun 11.

Centre for Integrative Physiology, School of Biomedical Sciences, The University of Edinburgh, Edinburgh, EH8 9XD, United Kingdom.

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http://dx.doi.org/10.1002/jbm.a.34813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243028PMC
May 2014

Cell patterning on photolithographically defined parylene-C: SiO2 substrates.

J Vis Exp 2014 Mar 7(85). Epub 2014 Mar 7.

School of Engineering, Institute for Integrated Micro and Nano Systems, The University of Edinburgh.

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http://dx.doi.org/10.3791/50929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143168PMC
March 2014

Chronic subdural haematoma: How can we improve patient care and outcomes?

Br J Neurosurg 2014 Jan 11;28(1):136-7. Epub 2013 Dec 11.

Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge , Cambridge , UK.

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http://dx.doi.org/10.3109/02688697.2013.869555DOI Listing
January 2014

Somatic retrotransposition alters the genetic landscape of the human brain.

Nature 2011 Oct 30;479(7374):534-7. Epub 2011 Oct 30.

Division of Genetics and Genomics, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Edinburgh EH25 9RG, UK.

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http://dx.doi.org/10.1038/nature10531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224101PMC
October 2011

Spontaneous subdural haematoma in a healthy young male.

BMJ Case Rep 2011 Jul 27;2011. Epub 2011 Jul 27.

Deparment of Clinical Neurosciences, Western General Hospital, Edinburgh, Midlothian, UK.

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http://dx.doi.org/10.1136/bcr.01.2011.3694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149419PMC
July 2011

Multiple schwannomatosis caused by the recently described INI1 gene--molecular pathology, and implications for prognosis.

Br J Neurosurg 2011 Jun 20;25(3):330-2. Epub 2010 Sep 20.

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.3109/02688697.2010.507278DOI Listing
June 2011

The Internet for neurosurgeons: current resources and future challenges.

Br J Neurosurg 2011 Jun 18;25(3):347-51. Epub 2011 Apr 18.

Department of Clinical Neurosciences, Western General Hospital, Crewe Road South, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3109/02688697.2011.554582DOI Listing
June 2011

Prion protein accumulation and neuroprotection in hypoxic brain damage.

Am J Pathol 2004 Jul;165(1):227-35

National Creutzfeldt-Jakob Disease Surveillance Unit and Pathology (Neuropathology), School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, Scotland, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618524PMC
http://dx.doi.org/10.1016/S0002-9440(10)63291-9DOI Listing
July 2004