Paul Lanken

Paul Lanken

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Paul Lanken

Paul Lanken

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Plasma Mitochondrial DNA Levels Are Associated With ARDS in Trauma and Sepsis Patients.

Chest 2019 Oct 14. Epub 2019 Oct 14.

Pulmonary, Allergy and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Center for Translational Lung Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.chest.2019.09.028DOI Listing
October 2019

Medical Student Perceptions of the Learning Environment: Learning Communities Are Associated With a More Positive Learning Environment in a Multi-Institutional Medical School Study.

Acad Med 2016 09;91(9):1263-9

S.D. Smith is associate clinical professor, Department of Family Medicine and Public Health, University of California, San Diego, School of Medicine, San Diego, California. L. Dunham is data analyst II, Medical Education Outcomes, American Medical Association, Chicago, Illinois. M. Dekhtyar is research associate, Medical Education Outcomes, American Medical Association, Chicago, Illinois. A. Dinh is institutional research analyst, Office of Institutional Research, Evaluation, and Assessment, University of Massachusetts Medical School, Worcester, Massachusetts. P.N. Lanken is professor of medicine and medical ethics and health policy and associate dean for professionalism and humanism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. K.F. Moynahan is professor and deputy dean for education, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona. M.L. Stuber is professor and assistant dean for well-being and career advising, Department of Psychiatry, David Geffen Medical School, University of California, Los Angeles, California. S.E. Skochelak is group vice president, Medical Education, American Medical Association, Chicago, Illinois.

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http://Insights.ovid.com/crossref?an=00001888-201609000-0002
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http://dx.doi.org/10.1097/ACM.0000000000001214DOI Listing
September 2016

Plasma Levels of Receptor Interacting Protein Kinase-3 (RIP3), an Essential Mediator of Necroptosis, are Associated with Acute Kidney Injury in Critically Ill Trauma Patients.

Shock 2016 08;46(2):139-43

*Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania †Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania ‡Center for Translational Lung Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania §Division of Traumatology, Surgical Critical Care, and Emergency Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania ||Center for Resuscitation Science, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania ¶Renal, Electrolyte, and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/SHK.0000000000000596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949076PMC
August 2016

The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis.

Clin J Am Soc Nephrol 2015 Nov 4;10(11):1911-20. Epub 2015 Sep 4.

Divisions of Pulmonary, Allergy, and Critical Care and Center for Clinical Epidemiology and Biostatistics, and.

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http://dx.doi.org/10.2215/CJN.12201214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633800PMC
November 2015

Efficacy of an internet-based learning module and small-group debriefing on trainees' attitudes and communication skills toward patients with substance use disorders: results of a cluster randomized controlled trial.

Acad Med 2015 Mar;90(3):345-54

Dr. Lanken is associate dean for professionalism and humanism and professor of medicine and medical ethics and health policy, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Dr. Novack is associate dean for medical education and professor of medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania. Dr. Daetwyler is associate professor of family medicine and community and preventive medicine and developer of online resources for medical education, Drexel University College of Medicine, Philadelphia, Pennsylvania. Dr. Gallop is instructor in biostatistics, West Chester University, West Chester, Pennsylvania. Dr. Landis is professor and director, Division of Biostatistics, Department of Biostatistics and Epidemiology, and faculty director, Clinical Research Computing Unit, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Dr. Lapin is director of graduate medical education evaluation and research, Office of Evaluation and Assessment, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Dr. Subramaniam is team leader and medical officer, Center for Clinical Trials Network, National Institute on Drug Abuse, Bethesda, Maryland. Dr. Schindler was vice dean for educational and academic affairs, Drexel University College of Medicine, at the time this study was conducted. She remains professor of psychiatry and pediatrics, Drexel University College of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/ACM.0000000000000506DOI Listing
March 2015

Computed tomography-defined abdominal adiposity is associated with acute kidney injury in critically ill trauma patients*.

Crit Care Med 2014 Jul;42(7):1619-28

1Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 2Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 3Division of Traumatology, Surgical Critical Care, and Emergency Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 4Drexel University School of Public Health, Philadelphia, PA. 5Renal, Electrolyte, and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 6Cardiovascular Medicine Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 7Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 8Center for Translational Lung Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000000306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230013PMC
July 2014

ABO blood type A is associated with increased risk of ARDS in whites following both major trauma and severe sepsis.

Chest 2014 Apr;145(4):753-761

Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://journal.publications.chestnet.org/data/Journals/CHEST
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http://journal.publications.chestnet.org/data/Journals/CHEST
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http://linkinghub.elsevier.com/retrieve/pii/S001236921535944
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http://dx.doi.org/10.1378/chest.13-1962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971970PMC
April 2014

IL1RN coding variant is associated with lower risk of acute respiratory distress syndrome and increased plasma IL-1 receptor antagonist.

Am J Respir Crit Care Med 2013 May;187(9):950-9

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1164/rccm.201208-1501OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707367PMC
May 2013

Lower serum endocan levels are associated with the development of acute lung injury after major trauma.

J Crit Care 2012 Oct 29;27(5):522.e11-7. Epub 2011 Sep 29.

Pulmonary, Allergy, and Critical Care Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jcrc.2011.07.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790584PMC
October 2012

The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury.

Am J Respir Crit Care Med 2012 Jun 6;185(12):1307-15. Epub 2012 Apr 6.

Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, 836 W. Gates Pavilion, 3400 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1164/rccm.201111-2025OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381234PMC
June 2012

SNP-set analysis replicates acute lung injury genetic risk factors.

BMC Med Genet 2012 Jun 28;13:52. Epub 2012 Jun 28.

Department of Medicine: Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine University of Pennsylvania, 3600 Spruce Street, 874 Maloney, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/1471-2350-13-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512475PMC
June 2012

Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma.

BMC Med Genet 2011 May 31;12:77. Epub 2011 May 31.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, USA.

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http://dx.doi.org/10.1186/1471-2350-12-77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121666PMC
May 2011

Performance of an automated electronic acute lung injury screening system in intensive care unit patients.

Crit Care Med 2011 Jan;39(1):98-104

Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e3181feb4a0DOI Listing
January 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2010.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014369PMC
January 2011

An alternative method of acute lung injury classification for use in observational studies.

Chest 2010 Nov 24;138(5):1054-61. Epub 2010 Jun 24.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Blockley Hall, 423 Guardian Dr, Philadelphia, PA, USA.

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http://dx.doi.org/10.1378/chest.09-2697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972624PMC
November 2010

Team training of medical students in the 21st century: would Flexner approve?

Acad Med 2010 Feb;85(2):254-9

Academic Programs Office, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1097/ACM.0b013e3181c8845eDOI Listing
February 2010

Association of physical examination with pulmonary artery catheter parameters in acute lung injury.

Crit Care Med 2009 Oct;37(10):2720-6

Pulmonary and Critical Care, Intermountain Medical Center and the University of Utah School of Medicine, Salt Lake City, UT, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900681PMC
http://dx.doi.org/10.1097/ccm.0b013e3181a59532DOI Listing
October 2009

Validation study of an automated electronic acute lung injury screening tool.

J Am Med Inform Assoc 2009 Jul-Aug;16(4):503-8. Epub 2009 Apr 23.

University of Pennsylvania Medical Center; Pulmonary; Allergy and Critical Care Division, Philadelphia, PA, USA.

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http://dx.doi.org/10.1197/jamia.M3120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705253PMC
September 2009

Association of human NAD(P)H:quinone oxidoreductase 1 (NQO1) polymorphism with development of acute lung injury.

J Cell Mol Med 2009 Aug;13(8B):1784-91

Duke University Medical Center, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Durham, NC, USA.

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http://dx.doi.org/10.1111/j.1582-4934.2008.00581.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829347PMC
August 2009

Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma.

Crit Care Med 2008 Oct;36(10):2794-800

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1097/ccm.0b013e318186b843DOI Listing
October 2008

The impact of development of acute lung injury on hospital mortality in critically ill trauma patients.

Crit Care Med 2008 Aug;36(8):2309-15

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1097/CCM.0b013e318180dc74DOI Listing
August 2008

Potential reasons why physicians underuse lung-protective ventilation: a retrospective cohort study using physician documentation.

Respir Care 2008 Apr;53(4):455-61

Division of Pulmonary, Allergy, and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

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April 2008

Association of RBC transfusion with mortality in patients with acute lung injury.

Chest 2007 Oct 15;132(4):1116-23. Epub 2007 May 15.

Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, MSTF Bldg, Room 800, 685 W Baltimore St, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1378/chest.07-0145DOI Listing
October 2007

Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury.

FASEB J 2007 Jul 23;21(9):2237-46. Epub 2007 Mar 23.

Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1096/fj.06-7759comDOI Listing
July 2007

Identification of immunoglobulins that recognize 3-nitrotyrosine in patients with acute lung injury after major trauma.

Am J Respir Cell Mol Biol 2007 Feb 5;36(2):152-7. Epub 2006 Oct 5.

Stokes Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, PA 19104-4318, USA.

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http://dx.doi.org/10.1165/rcmb.2006-0288SMDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899311PMC
February 2007

Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome.

N Engl J Med 2006 Apr;354(16):1671-84

Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Box 359762, 325 Ninth Ave., Seattle, WA 98104, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa051693
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http://dx.doi.org/10.1056/NEJMoa051693DOI Listing
April 2006

Underuse of lung protective ventilation: analysis of potential factors to explain physician behavior.

Crit Care Med 2006 Feb;34(2):300-6

Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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http://pdfs.journals.lww.com/ccmjournal/2006/02000/Underuse_
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http://dx.doi.org/10.1097/01.ccm.0000198328.83571.4aDOI Listing
February 2006

Longitudinal small-group learning during the first clinical year.

Fam Med 2004 Jan;36 Suppl:S83-8

Department of Pediatrics, Case Western Reserve University, USA.

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January 2004

Resource utilization among patients with sepsis syndrome.

Infect Control Hosp Epidemiol 2003 Jan;24(1):62-70

Division of General Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1086/502117DOI Listing
January 2003

Images in clinical medicine. Pulmonary alveolar proteinosis.

N Engl J Med 2002 Dec;347(26):2133

Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1056/NEJMicm990808DOI Listing
December 2002