Publications by authors named "Paul L Fox"

100Publications

3-Dimensional architecture of the human multi-tRNA synthetase complex.

Nucleic Acids Res 2020 09;48(15):8740-8754

Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1093/nar/gkaa569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470956PMC
September 2020

Protein S-Nitrosylation of Human Cytomegalovirus pp71 Inhibits Its Ability To Limit STING Antiviral Responses.

J Virol 2020 Aug 17;94(17). Epub 2020 Aug 17.

Microbiology and Immunology Department, SUNY Upstate Medical University, Syracuse, New York, USA

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http://dx.doi.org/10.1128/JVI.00033-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431796PMC
August 2020

Aminoacyl-tRNA synthetases as therapeutic targets.

Nat Rev Drug Discov 2019 08;18(8):629-650

Medicinal Bioconvergence Research Center, Seoul National University, Yeongtong-gu, Suwon-si, Gyeonggi-do, Korea.

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http://dx.doi.org/10.1038/s41573-019-0026-3DOI Listing
August 2019

Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection.

Mol Cell 2019 02 3;73(3):446-457.e6. Epub 2019 Jan 3.

Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765183098
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http://dx.doi.org/10.1016/j.molcel.2018.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415305PMC
February 2019

Metabolic origin of the fused aminoacyl-tRNA synthetase, glutamyl-prolyl-tRNA synthetase.

J Biol Chem 2018 12 11;293(49):19148-19156. Epub 2018 Oct 11.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195

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http://www.jbc.org/lookup/doi/10.1074/jbc.RA118.004276
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http://dx.doi.org/10.1074/jbc.RA118.004276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295713PMC
December 2018

The GAIT translational control system.

Wiley Interdiscip Rev RNA 2018 03 20;9(2). Epub 2017 Nov 20.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1002/wrna.1441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815886PMC
March 2018

Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells.

PLoS Genet 2017 Oct 13;13(10):e1007051. Epub 2017 Oct 13.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656329PMC
October 2017

Unexpected metabolic function of a tRNA synthetase.

Cell Cycle 2017 7;16(23):2239-2240. Epub 2017 Dec 7.

a Department of Cellular and Molecular Medicine , Lerner Research Institute, Cleveland Clinic , Cleveland , OH , USA.

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https://www.tandfonline.com/doi/full/10.1080/15384101.2017.1
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http://dx.doi.org/10.1080/15384101.2017.1324127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788480PMC
May 2019

Interplay between miR-574-3p and hnRNP L regulates VEGFA mRNA translation and tumorigenesis.

Nucleic Acids Res 2017 Jul;45(13):7950-7964

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://academic.oup.com/nar/article/45/13/7950/3829199
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http://dx.doi.org/10.1093/nar/gkx440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570063PMC
July 2017

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.

Nature 2017 02 8;542(7641):357-361. Epub 2017 Feb 8.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1038/nature21380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480610PMC
February 2017

Experimental approaches for investigation of aminoacyl tRNA synthetase phosphorylation.

Methods 2017 01 8;113:72-82. Epub 2016 Oct 8.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2016.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253304PMC
January 2017

Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity.

Nat Immunol 2016 Nov 5;17(11):1252-1262. Epub 2016 Sep 5.

Infection and Immunity Research Laboratory, Microbiomics and Immunity Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea.

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http://dx.doi.org/10.1038/ni.3542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173487PMC
November 2016

Antiangiogenic VEGF-Ax: A New Participant in Tumor Angiogenesis.

Cancer Res 2015 Jul 29;75(14):2765-9. Epub 2015 Jun 29.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506224PMC
July 2015

Translational control mechanisms in angiogenesis and vascular biology.

Curr Atheroscler Rep 2015 May;17(5):506

Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, 9500 Euclid Avenue/NC10, Cleveland, OH, 44195, USA.

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http://dx.doi.org/10.1007/s11883-015-0506-9DOI Listing
May 2015

Discovery and investigation of the GAIT translational control system.

Authors:
Paul L Fox

RNA 2015 Apr;21(4):615-8

Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio 44195, USA

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http://dx.doi.org/10.1261/rna.050187.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371305PMC
April 2015

Target-selective protein S-nitrosylation by sequence motif recognition.

Cell 2014 Oct 16;159(3):623-34. Epub 2014 Oct 16.

Department of Cellular and Molecular Medicine, The Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(14)01181-7.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S009286741401181
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http://dx.doi.org/10.1016/j.cell.2014.09.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243042PMC
October 2014

Ceruloplasmin has two nearly identical sites that bind myeloperoxidase.

Biochem Biophys Res Commun 2014 Oct 6;453(4):722-7. Epub 2014 Oct 6.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.bbrc.2014.09.134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253670PMC
October 2014

Origin and evolution of glutamyl-prolyl tRNA synthetase WHEP domains reveal evolutionary relationships within Holozoa.

PLoS One 2014 26;9(6):e98493. Epub 2014 Jun 26.

Department of Cellular and Molecular Medicine, The Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, Unites States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098493PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072531PMC
October 2015

Programmed translational readthrough generates antiangiogenic VEGF-Ax.

Cell 2014 Jun;157(7):1605-18

Department of Cellular and Molecular Medicine, The Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.04.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113015PMC
June 2014

Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation.

Nat Cell Biol 2014 May 20;16(5):445-56. Epub 2014 Apr 20.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue Cleveland, Ohio 44195, USA.

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http://www.nature.com/articles/ncb2954
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http://dx.doi.org/10.1038/ncb2954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036069PMC
May 2014

The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA.

PLoS Biol 2013 20;11(8):e1001635. Epub 2013 Aug 20.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1371/journal.pbio.1001635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747992PMC
March 2014

Function and distribution of apolipoprotein A1 in the artery wall are markedly distinct from those in plasma.

Circulation 2013 Oct 22;128(15):1644-55. Epub 2013 Aug 22.

Departments of Cellular and Molecular Medicine, Lerner Research Institute (J.A.D., Y.H., K.A., G.G., V.G., P.L.F., W.H.W.T., J.D.S., S.L.H.), Cardiovascular Medicine, Heart, and Vascular Institute (W.H.W.T., J.D.S., S.L.H.), and Molecular Cardiology, Lerner Research Institute (E.F.P.), Cleveland Clinic, Cleveland, OH; Department of Medicine, New York University, New York, NY (O.E.-O., E.A.F.); and Departments of Chemistry (G.G., V.G., S.L.H.) and Mathematics (Y.W.), Cleveland State University, Cleveland, OH.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882895PMC
October 2013

Non-catalytic regulation of gene expression by aminoacyl-tRNA synthetases.

Top Curr Chem 2014 ;344:167-87

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.

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http://dx.doi.org/10.1007/128_2013_422DOI Listing
August 2014

Aminoacyl-tRNA synthetases in medicine and disease.

Authors:
Peng Yao Paul L Fox

EMBO Mol Med 2013 Mar 21;5(3):332-43. Epub 2013 Feb 21.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1002/emmm.201100626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598075PMC
March 2013

Citric acid cycle and the origin of MARS.

Trends Biochem Sci 2013 May 14;38(5):222-8. Epub 2013 Feb 14.

Department of Cellular & Molecular Medicine, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue/NC10, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.tibs.2013.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634881PMC
May 2013

Regulation and dysregulation of 3'UTR-mediated translational control.

Curr Opin Genet Dev 2013 Feb 9;23(1):29-34. Epub 2013 Jan 9.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue/NC10, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.gde.2012.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644486PMC
February 2013

Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.

Mol Cell Biol 2012 Dec 15;32(24):5046-55. Epub 2012 Oct 15.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1128/MCB.01168-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510535PMC
December 2012

Stimulus-dependent phosphorylation of profilin-1 in angiogenesis.

Nat Cell Biol 2012 Oct 23;14(10):1046-56. Epub 2012 Sep 23.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1038/ncb2580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619429PMC
October 2012

Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells.

J Cell Biol 2012 Jul;198(1):47-55

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.201111088
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http://dx.doi.org/10.1083/jcb.201111088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392929PMC
July 2012

Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation.

Mol Cell 2012 Aug 5;47(4):656-63. Epub 2012 Jul 5.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10972765120049
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http://dx.doi.org/10.1016/j.molcel.2012.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635105PMC
August 2012

A truncated tRNA synthetase directs a "translational trickle" of gene expression.

Authors:
Peng Yao Paul L Fox

Cell Cycle 2012 May 15;11(10):1868-9. Epub 2012 May 15.

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http://dx.doi.org/10.4161/cc.20417DOI Listing
May 2012

Protective role of macrophage-derived ceruloplasmin in inflammatory bowel disease.

Gut 2013 Feb 16;62(2):209-19. Epub 2012 Feb 16.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1136/gutjnl-2011-300694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595056PMC
February 2013

HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules.

Mol Cell Biol 2012 Apr 23;32(7):1202-13. Epub 2012 Jan 23.

Department of Cell Biology, Lerner Research Institute and Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1128/MCB.05977-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302442PMC
April 2012

Clinical and genetic association of serum ceruloplasmin with cardiovascular risk.

Arterioscler Thromb Vasc Biol 2012 Feb 10;32(2):516-22. Epub 2011 Nov 10.

Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Ave, Desk J3-4, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1161/ATVBAHA.111.237040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262121PMC
February 2012

Sex lethal and upstream ORFs: a bait-and-trap system for ribosomes.

Authors:
Peng Yao Paul L Fox

Genome Biol 2011 Jul 25;12(7):121. Epub 2011 Jul 25.

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1186/gb-2011-12-7-121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218820PMC
July 2011

Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L.

EMBO J 2011 Apr 22;30(7):1324-34. Epub 2011 Feb 22.

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://emboj.embopress.org/cgi/doi/10.1038/emboj.2011.38
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http://dx.doi.org/10.1038/emboj.2011.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094116PMC
April 2011

Phosphorylation of glutamyl-prolyl tRNA synthetase by cyclin-dependent kinase 5 dictates transcript-selective translational control.

Proc Natl Acad Sci U S A 2011 Jan 10;108(4):1415-20. Epub 2011 Jan 10.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1073/pnas.1011275108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029695PMC
January 2011

GAPDH regulates cellular heme insertion into inducible nitric oxide synthase.

Proc Natl Acad Sci U S A 2010 Oct 4;107(42):18004-9. Epub 2010 Oct 4.

Department of Pathobiology,Lerner Research institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1073/pnas.1008133107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964200PMC
October 2010

Evolution of function of a fused metazoan tRNA synthetase.

Mol Biol Evol 2011 Jan 9;28(1):437-47. Epub 2010 Sep 9.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, USA.

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http://dx.doi.org/10.1093/molbev/msq246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002251PMC
January 2011

TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI.

Nat Cell Biol 2010 Mar 14;12(3):286-93. Epub 2010 Feb 14.

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1038/ncb2029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830561PMC
March 2010

Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activity.

Mol Cell 2009 Jul;35(2):164-80

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.05.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752289PMC
July 2009

The GAIT system: a gatekeeper of inflammatory gene expression.

Trends Biochem Sci 2009 Jul 15;34(7):324-31. Epub 2009 Jun 15.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, OH 44195, USA.

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http://www.mnf.uni-greifswald.de/fileadmin/Zoologisches_Muse
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http://linkinghub.elsevier.com/retrieve/pii/S096800040900100
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http://dx.doi.org/10.1016/j.tibs.2009.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637685PMC
July 2009

A stress-responsive RNA switch regulates VEGFA expression.

Nature 2009 Feb 21;457(7231):915-9. Epub 2008 Dec 21.

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1038/nature07598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858559PMC
February 2009

Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3'-untranslated region: implications in neurodegenerative diseases.

J Biol Chem 2009 Jan 18;284(3):1873-83. Epub 2008 Nov 18.

Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110 067, India.

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http://dx.doi.org/10.1074/jbc.M804079200DOI Listing
January 2009

DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression.

Mol Cell 2008 Nov;32(3):371-82

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644327PMC
November 2008

WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression.

Mol Cell 2008 Mar;29(6):679-90

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819395PMC
March 2008

A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity.

EMBO J 2007 Jul 5;26(14):3360-72. Epub 2007 Jul 5.

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1038/sj.emboj.7601774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933405PMC
July 2007

Macromolecular complexes as depots for releasable regulatory proteins.

Trends Biochem Sci 2007 Apr 23;32(4):158-64. Epub 2007 Feb 23.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue/NC10, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.tibs.2007.02.003DOI Listing
April 2007

L13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational control.

Mol Cell 2007 Jan;25(1):113-26

Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, OH 44115, USA.

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http://dx.doi.org/10.1016/j.molcel.2006.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810376PMC
January 2007

Caveolin-1 polarization in migrating endothelial cells is directed by substrate topology not chemoattractant gradient.

Cell Motil Cytoskeleton 2006 Nov;63(11):673-80

Department of Anesthesiology Research, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1002/cm.20153DOI Listing
November 2006

Translational control of ceruloplasmin gene expression: beyond the IRE.

Biol Res 2006 ;39(1):59-66

Department of Biology, Cleveland State University, Cleveland, OH, USA.

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http://dx.doi.org/10.4067/s0716-97602006000100007DOI Listing
February 2007

Unexpected role of ceruloplasmin in intestinal iron absorption.

Cell Metab 2005 Nov;2(5):309-19

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/j.cmet.2005.10.003DOI Listing
November 2005

Regulation of macrophage ceruloplasmin gene expression: one paradigm of 3'-UTR-mediated translational control.

Mol Cells 2005 Oct;20(2):167-72

Department of Biology, Geology, and Environmental Sciences, Cleveland State University, Cleveland, OH, USA.

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October 2005

Protein kinase Cdelta-dependent phosphorylation of syndecan-4 regulates cell migration.

Circ Res 2005 Sep 1;97(7):674-81. Epub 2005 Sep 1.

Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1161/01.RES.0000184667.82354.b1DOI Listing
September 2005

Equality of the sexes: found in translation.

Cell 2005 Aug;122(4):492-3

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009286740500808
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http://dx.doi.org/10.1016/j.cell.2005.08.005DOI Listing
August 2005

Role of reactive oxygen species in inhibition of endothelial cell migration by oxidized low-density lipoprotein.

J Vasc Surg 2004 Dec;40(6):1208-15

Department of Surgery, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1016/j.jvs.2004.09.020DOI Listing
December 2004

Anemia and impaired stress-induced erythropoiesis in aceruloplasminemic mice.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):346-55

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.bcmd.2004.07.003DOI Listing
April 2005

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation.

Cell 2004 Oct;119(2):195-208

Department of Cell Biology, The Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.cell.2004.09.030DOI Listing
October 2004

Oxidative stress, caveolae and caveolin-1.

Subcell Biochem 2004 ;37:425-41

Departments of Anesthesiology Research and Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1007/978-1-4757-5806-1_13DOI Listing
November 2004

Polarization of plasma membrane microviscosity during endothelial cell migration.

Dev Cell 2004 Jan;6(1):29-41

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/s1534-5807(03)00397-6DOI Listing
January 2004

Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control.

Cell 2003 Oct;115(2):187-98

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00773-6DOI Listing
October 2003

Role of ceruloplasmin in macrophage iron efflux during hypoxia.

J Biol Chem 2003 Nov 2;278(45):44018-24. Epub 2003 Sep 2.

Department of Cell Biology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1074/jbc.M304926200DOI Listing
November 2003

Differential caveolin-1 polarization in endothelial cells during migration in two and three dimensions.

Mol Biol Cell 2003 Aug 3;14(8):3156-68. Epub 2003 May 3.

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1091/mbc.e02-11-0761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC181557PMC
August 2003

Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region.

Mol Cell Biol 2003 Mar;23(5):1509-19

Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151701PMC
http://dx.doi.org/10.1128/mcb.23.5.1509-1519.2003DOI Listing
March 2003