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Paul Kalitsis | PubFacts

Publications by authors named "Paul Kalitsis"

33Publications

Topoisomerase IIα is essential for maintenance of mitotic chromosome structure.

Proc Natl Acad Sci U S A 2020 06 15;117(22):12131-12142. Epub 2020 May 15.

Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC 3052, Australia;

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June 2020

Loss of TOP3B leads to increased R-loop formation and genome instability.

Open Biol 2019 12 4;9(12):190222. Epub 2019 Dec 4.

Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia.

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December 2019

Effect of MUC1 length polymorphisms on the NLRP3 inflammasome response of human macrophages.

Hum Immunol 2019 Oct 15;80(10):878-882. Epub 2019 Jun 15.

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria 3052, Australia; Faculty of Veterinary and Agricultural Science, The University of Melbourne, Parkville, VIC 3010, Australia; Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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October 2019

Knocking in Multifunctional Gene Tags into SMC Complex Subunits Using Gene Editing.

Methods Mol Biol 2019 ;2004:91-102

Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, VIC, Australia.

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March 2020

A Roberts Syndrome Individual With Differential Genotoxin Sensitivity and a DNA Damage Response Defect.

Int J Radiat Oncol Biol Phys 2019 04 30;103(5):1194-1202. Epub 2018 Nov 30.

Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Clinical Pathology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria, Australia; College of Life Sciences, Shanxi Normal University, Linfen, Shanxi, China. Electronic address:

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April 2019

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

Proc Natl Acad Sci U S A 2018 05 18;115(18):4737-4742. Epub 2018 Apr 18.

Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia;

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May 2018

The Role of Centromere Defects in Cancer.

Prog Mol Subcell Biol 2017;56:541-554

Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Melbourne, 3052, Australia.

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May 2019

Condensin, master organizer of the genome.

Chromosome Res 2017 03 9;25(1):61-76. Epub 2017 Feb 9.

From Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, VIC, 3052, Australia.

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March 2017

Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome.

PLoS Genet 2016 Dec 15;12(12):e1006483. Epub 2016 Dec 15.

Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Parkville, Victoria, Australia.

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December 2016

Active centromere and chromosome identification in fixed cell lines.

Mol Cytogenet 2016 22;9:28. Epub 2016 Mar 22.

Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Melbourne, VIC 3052 Australia ; Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Parkville, Melbourne, VIC 3052 Australia.

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March 2016

Condensin I and II behaviour in interphase nuclei and cells undergoing premature chromosome condensation.

Chromosome Res 2016 05 23;24(2):243-69. Epub 2016 Mar 23.

Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, VIC, 3052, Australia.

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May 2016

Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo.

Metallomics 2015 Oct 25;7(10):1390-8. Epub 2015 Sep 25.

The Department of Surgery, University of Melbourne, Austin Health, Studley Rd, Heidelberg, Victoria 3084, Australia.

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October 2015

Disruption of a conserved CAP-D3 threonine alters condensin loading on mitotic chromosomes leading to chromosome hypercondensation.

J Biol Chem 2015 Mar 20;290(10):6156-67. Epub 2015 Jan 20.

From the Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052 and the Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria 3052, Australia

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March 2015

Chromosome Y centromere array deletion leads to impaired centromere function.

PLoS One 2014 22;9(1):e86875. Epub 2014 Jan 22.

Murdoch Childrens Research Institute, Melbourne, Victoria, Australia ; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.

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September 2014

Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes.

Nat Commun 2013 ;4:2537

1] Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Melbourne, Victoria 3052, Australia [2] Department of Paediatrics, University of Melbourne, Parkville, Melbourne, Victoria 3052, Australia.

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May 2014

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells.

PLoS Genet 2012 Sep 6;8(9):e1002919. Epub 2012 Sep 6.

Theme of Genetic Disorders, Murdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.

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September 2012

The evolutionary life cycle of the resilient centromere.

Chromosoma 2012 Aug 11;121(4):327-40. Epub 2012 Apr 11.

Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia.

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August 2012

Streptavidin-Binding Peptide (SBP)-tagged SMC2 allows single-step affinity fluorescence, blotting or purification of the condensin complex.

BMC Biochem 2010 Dec 31;11:50. Epub 2010 Dec 31.

Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia.

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December 2010

Inherent promoter bidirectionality facilitates maintenance of sequence integrity and transcription of parasitic DNA in mammalian genomes.

BMC Genomics 2009 Oct 27;10:498. Epub 2009 Oct 27.

Chromosome and Chromatin Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Melbourne 3052, Victoria, Australia.

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October 2009

Orchestrating twosome and foursome chromosome parties.

Dev Cell 2009 Sep;17(3):305-7

Murdoch Childrens Research Institute, Royal Children's Hospital and Melbourne University Department of Paediatrics, Parkville, Melbourne, Victoria, 3052, Australia.

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September 2009

Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.

Genome Res 2009 Dec 8;19(12):2202-13. Epub 2009 Sep 8.

Murdoch Childrens Research Institute, Victoria, Australia.

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December 2009

Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation.

Proc Natl Acad Sci U S A 2006 Jun 26;103(23):8786-91. Epub 2006 May 26.

Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia.

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June 2006

Spef1, a conserved novel testis protein found in mouse sperm flagella.

Gene 2005 Jul;353(2):189-99

Chromosome Research Laboratory, Murdoch Children's Research Institute, Royal Children's Hospital, Department of Paediatrics, University of Melbourne, Parkville 3052, Melbourne, Australia.

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July 2005

Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice.

Genes Chromosomes Cancer 2005 Sep;44(1):29-36

Chromosome Research Laboratory, Murdoch Childrens Research Institute, Department of Paediatrics, Royal Children's Hospital, Melbourne, Australia.

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September 2005

Building the centromere: from foundation proteins to 3D organization.

Trends Cell Biol 2004 Jul;14(7):359-68

Murdoch Childrens Research Institute, Royal Children's Hospital, Flemington Road, Parkville, Melbourne, Victoria 3052, Australia.

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July 2004

Partially functional Cenpa-GFP fusion protein causes increased chromosome missegregation and apoptosis during mouse embryogenesis.

Chromosome Res 2003 ;11(4):345-57

Murdoch Childrenś Research Institute, Royal Children's Hospital, Flemington Road, Parkville 3052, Melbourne, Victoria, Australia.

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March 2004

Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc.

Hum Mol Genet 2002 Sep;11(19):2319-29

The Murdoch Childrens Research Institute, Royal Children's Hospital, Flemington Road, Parkville 3052, Australia.

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September 2002

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated.

J Biol Chem 2002 Jul 13;277(30):26921-6. Epub 2002 May 13.

Murdoch Childrens Research Institute, Royal Children's Hospital, Flemington Rd., Parkville 3052, Australia.

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July 2002