Paul K H Tam

Paul K H Tam

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Paul K H Tam

Publications by authors named "Paul K H Tam"

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Recent trends in the prevalence of Helicobacter Pylori in symptomatic children: A 12-year retrospective study in a tertiary centre.

J Pediatr Surg 2019 Feb 6;54(2):255-257. Epub 2018 Nov 6.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2018.10.079DOI Listing
February 2019

The Role of Neonatal Gr-1 Myeloid Cells in a Murine Model of Rhesus-Rotavirus-Induced Biliary Atresia.

Am J Pathol 2018 11 8;188(11):2617-2628. Epub 2018 Sep 8.

Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China; Department of Surgery, the University of Hong Kong, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.07.024DOI Listing
November 2018

Corrigendum to "Cholangiopathies - Towards a molecular understanding" [EBioMedicine 35 (2018) 381-393].

EBioMedicine 2018 10 9;36:564. Epub 2018 Oct 9.

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden; Department of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.09.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197698PMC
October 2018

Cholangiopathies - Towards a molecular understanding.

EBioMedicine 2018 Sep 17;35:381-393. Epub 2018 Sep 17.

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden; Department of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.08.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161480PMC
September 2018

Congenital pulmonary airway malformation: advances and controversies.

Lancet Child Adolesc Health 2018 04 17;2(4):290-297. Epub 2018 Feb 17.

Department of Surgery, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.

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http://dx.doi.org/10.1016/S2352-4642(18)30035-XDOI Listing
April 2018

Peroral Endoscopic Myotomy with EndoFLIP and Double-Endoscope: Novel Techniques for Achalasia in Pediatric Population.

J Laparoendosc Adv Surg Tech A 2018 Mar 7;28(3):343-347. Epub 2017 Dec 7.

Department of Surgery, University of Hong Kong Medical Center , Queen Mary Hospital, Hong Kong SAR, China .

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http://dx.doi.org/10.1089/lap.2017.0268DOI Listing
March 2018

Actionable secondary findings from whole-genome sequencing of 954 East Asians.

Hum Genet 2018 Jan 11;137(1):31-37. Epub 2017 Nov 11.

Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1007/s00439-017-1852-1DOI Listing
January 2018

Long-term implications and global impact of paediatric surgery.

Lancet 2017 Sep;390(10099):1012-1014

Department of Urology, Boston Children's Hospital, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1016/S0140-6736(17)32341-3DOI Listing
September 2017

Advances in paediatric urology.

Lancet 2017 Sep;390(10099):1061-1071

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01406736173228
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http://dx.doi.org/10.1016/S0140-6736(17)32282-1DOI Listing
September 2017

Advances in paediatric gastroenterology.

Lancet 2017 Sep;390(10099):1072-1082

Department of Paediatric Surgery, King's College Hospital, London, UK.

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http://dx.doi.org/10.1016/S0140-6736(17)32284-5DOI Listing
September 2017

Surgical Intervention for Primary Spontaneous Pneumothorax in Pediatric Population: When and Why?

J Laparoendosc Adv Surg Tech A 2017 Aug 18;27(8):841-844. Epub 2017 Jan 18.

Division of Paediatric Surgery, Department of Surgery, University of Hong Kong Medical Center , Queen Mary Hospital, Hong Kong, China .

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http://dx.doi.org/10.1089/lap.2016.0163DOI Listing
August 2017

Silver nanoparticle treatment ameliorates biliary atresia syndrome in rhesus rotavirus inoculated mice.

Nanomedicine 2017 04 25;13(3):1041-1050. Epub 2016 Nov 25.

Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2016.11.013DOI Listing
April 2017

Pneumovesical Ureteric Reimplantation in Pediatric Patients: An Intermediate Term Result.

J Laparoendosc Adv Surg Tech A 2017 Feb 2;27(2):203-205. Epub 2016 Nov 2.

Department of Surgery, The University of Hong Kong , Queen Mary Hospital, Hong Kong, China .

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http://dx.doi.org/10.1089/lap.2016.0236DOI Listing
February 2017

Predictors for bowel resection and the presence of a pathological lead point for operated childhood intussusception: A multi-center study.

J Pediatr Surg 2016 Dec 16;51(12):1998-2000. Epub 2016 Sep 16.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00223468163035
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http://dx.doi.org/10.1016/j.jpedsurg.2016.09.033DOI Listing
December 2016

Beneficial effects of mucous fistula refeeding in necrotizing enterocolitis neonates with enterostomies.

J Pediatr Surg 2016 Dec 15;51(12):1914-1916. Epub 2016 Sep 15.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1016/j.jpedsurg.2016.09.010DOI Listing
December 2016

Application of anchoring stitch prevents rectal prolapse in laparoscopic assisted anorectal pullthrough.

J Pediatr Surg 2016 Dec 17;51(12):2113-2116. Epub 2016 Sep 17.

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2016.09.051DOI Listing
December 2016

Role of CD56-expressing immature biliary epithelial cells in biliary atresia.

World J Gastroenterol 2016 Feb;22(8):2545-57

Rui-Zhong Zhang, Jia-Kang Yu, Jiao Peng, Yan Chen, Hui-Min Xia, Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong Province, China.

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http://dx.doi.org/10.3748/wjg.v22.i8.2545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768200PMC
February 2016

Hirschsprung's disease: A bridge for science and surgery.

Authors:
Paul K H Tam

J Pediatr Surg 2016 Jan 21;51(1):18-22. Epub 2015 Oct 21.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2015.10.021DOI Listing
January 2016

Childhood intussusception: 17-year experience at a tertiary referral centre in Hong Kong.

Hong Kong Med J 2015 Dec 11;21(6):518-23. Epub 2015 Sep 11.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://dx.doi.org/10.12809/hkmj144456DOI Listing
December 2015

Laparoscopic versus open operation for perforated peptic ulcer in pediatric patients: A 10-year experience.

J Pediatr Surg 2015 Dec 28;50(12):2038-40. Epub 2015 Aug 28.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00223468150053
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http://dx.doi.org/10.1016/j.jpedsurg.2015.08.025DOI Listing
December 2015

Bilateral Pheochromocytomas in MEN2A Syndrome: A Two-Institution Experience.

World J Surg 2015 Oct;39(10):2484-91

Department of Surgery, The University of Hong Kong, Hong Kong, SAR, China,

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http://dx.doi.org/10.1007/s00268-015-3117-2DOI Listing
October 2015

Use of robotic-assisted laparoscopic Mitrofanoff appendicovesicostomy in a paediatric patient: problem encountered.

Hong Kong Med J 2015 Oct;21(5):468-70

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://dx.doi.org/10.12809/hkmj144340DOI Listing
October 2015

SRY interference of normal regulation of the RET gene suggests a potential role of the Y-chromosome gene in sexual dimorphism in Hirschsprung disease.

Hum Mol Genet 2015 Feb 28;24(3):685-97. Epub 2014 Sep 28.

Department of Medicine Institute for Human Genetics, University of California, San Francisco, USA and

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http://dx.doi.org/10.1093/hmg/ddu488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291247PMC
February 2015

Biliary-enteric reconstruction with hepaticoduodenostomy following laparoscopic excision of choledochal cyst is associated with better postoperative outcomes: a single-centre experience.

Pediatr Surg Int 2015 Feb 30;31(2):149-53. Epub 2014 Nov 30.

Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1007/s00383-014-3648-xDOI Listing
February 2015

Laparoscopically assisted simple suturing obliteration (LASSO) of the internal ring using an epidural needle: a handy single-port laparoscopic herniorrhaphy in children.

J Pediatr Surg 2014 Dec 15;49(12):1818-20. Epub 2014 Nov 15.

Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.jpedsurg.2014.09.027DOI Listing
December 2014

Internationalization: the Hong Kong-China experience as a model for collaborative education in Asia.

Pediatr Surg Int 2013 Oct;29(10):1053-9

Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong,

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http://dx.doi.org/10.1007/s00383-013-3407-4DOI Listing
October 2013

Peanut aspiration: an avoidable life-threatening condition.

Hong Kong Med J 2012 Aug;18(4):340-2

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong.

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August 2012

Bile duct anastomotic stricture after pediatric living donor liver transplantation.

J Pediatr Surg 2012 Jul;47(7):1399-403

Department of Surgery, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1016/j.jpedsurg.2011.12.014DOI Listing
July 2012

Effects of water uptake on melamine renal stone formation in mice.

Nephrol Dial Transplant 2012 Jun 10;27(6):2225-31. Epub 2011 Oct 10.

Department of Surgery, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1093/ndt/gfr577DOI Listing
June 2012

Early post-operative interleukin-6 and tumor necrosis factor-α levels after single-port laparoscopic varicocelectomy in children.

Pediatr Surg Int 2012 Mar 13;28(3):281-6. Epub 2011 Oct 13.

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China.

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http://link.springer.com/10.1007/s00383-011-3011-4
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http://dx.doi.org/10.1007/s00383-011-3011-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284665PMC
March 2012

Functional analyses of RET mutations in Chinese Hirschsprung disease patients.

Birth Defects Res A Clin Mol Teratol 2012 Jan 1;94(1):47-51. Epub 2011 Dec 1.

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Hong Kong, Special Administrative Region, China.

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http://dx.doi.org/10.1002/bdra.22863DOI Listing
January 2012

Evaluation of defecative function 5 years or longer after laparoscopic-assisted pull-through for imperforate anus.

J Pediatr Surg 2011 Dec;46(12):2313-5

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.

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https://linkinghub.elsevier.com/retrieve/pii/S00223468110076
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http://dx.doi.org/10.1016/j.jpedsurg.2011.09.021DOI Listing
December 2011

Rosiglitazone promotes fatty acyl CoA accumulation and excessive glycogen storage in livers of mice without adiponectin.

J Hepatol 2010 Dec 4;53(6):1108-16. Epub 2010 Aug 4.

Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1016/j.jhep.2010.05.034DOI Listing
December 2010

Hirschsprung's disease.

Semin Pediatr Surg 2010 Aug;19(3):194-200

Department of Paediatric Surgery, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

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http://dx.doi.org/10.1053/j.sempedsurg.2010.03.004DOI Listing
August 2010

Haplotype analysis reveals a possible founder effect of RET mutation R114H for Hirschsprung's disease in the Chinese population.

PLoS One 2010 Jun 2;5(6):e10918. Epub 2010 Jun 2.

Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010918PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880000PMC
June 2010

Thoracoscopic repair of esophageal atresia through the right chest in neonates with right-sided aortic arch.

J Laparoendosc Adv Surg Tech A 2010 May;20(4):403-4

Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1089/lap.2009.0265DOI Listing
May 2010

Silver nanoparticles mediate differential responses in keratinocytes and fibroblasts during skin wound healing.

ChemMedChem 2010 Mar;5(3):468-75

Department of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/cmdc.200900502DOI Listing
March 2010

Transcriptional regulation of RET by Nkx2-1, Phox2b, Sox10, and Pax3.

J Pediatr Surg 2009 Oct;44(10):1904-12

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.jpedsurg.2008.11.055DOI Listing
October 2009

Thoracoscopic bullectomy for primary spontaneous pneumothorax in pediatric patients.

Pediatr Surg Int 2009 Sep;25(9):763-6

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China.

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http://link.springer.com/10.1007/s00383-009-2432-9
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http://dx.doi.org/10.1007/s00383-009-2432-9DOI Listing
September 2009

Impact of prenatal diagnosis on choledochal cysts and the benefits of early excision.

J Paediatr Child Health 2009 Jan-Feb;45(1-2):28-30

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China.

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http://doi.wiley.com/10.1111/j.1440-1754.2008.01424.x
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http://dx.doi.org/10.1111/j.1440-1754.2008.01424.xDOI Listing
July 2009

Further evidence of the anti-inflammatory effects of silver nanoparticles.

ChemMedChem 2009 Jul;4(7):1129-35

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/cmdc.200900049DOI Listing
July 2009

Genetic basis of Hirschsprung's disease.

Pediatr Surg Int 2009 Jul 12;25(7):543-58. Epub 2009 Jun 12.

Division of Paediatric Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Pok Fu Lam Road, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1007/s00383-009-2402-2DOI Listing
July 2009

Abdominal compartment syndrome after open biopsy in a child with bilateral Wilms' tumour.

Hong Kong Med J 2009 Apr;15(2):136-8

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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April 2009

A novel function for dendritic cell: clearance of VEGF via VEGF receptor-1.

Biochem Biophys Res Commun 2009 Mar 22;380(2):243-8. Epub 2009 Jan 22.

Department of Surgery, The University of Hong Kong, Hong Kong SAR, China.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0900081
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http://dx.doi.org/10.1016/j.bbrc.2009.01.043DOI Listing
March 2009

A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma.

J Natl Cancer Inst 2009 Feb 27;101(3):162-75. Epub 2009 Jan 27.

Department of Surgery, University of Hong Kong, Pokfulam, Faculty of Medicine Building, 21 Sassoon Rd, Hong Kong, SAR, China.

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http://dx.doi.org/10.1093/jnci/djn471DOI Listing
February 2009

Diagnosing acute appendicitis: are we overusing radiologic investigations?

J Pediatr Surg 2008 Dec;43(12):2239-41

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.

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http://linkinghub.elsevier.com/retrieve/pii/S002234680800753
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http://dx.doi.org/10.1016/j.jpedsurg.2008.08.054DOI Listing
December 2008

Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury.

Hepatology 2008 Oct;48(4):1087-96

Department of Pharmacology, Institute of Molecular Technology for Drug Discovery and Synthesis, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1002/hep.22444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597507PMC
October 2008

Prokineticin-signaling pathway.

Int J Biochem Cell Biol 2008 21;40(9):1679-84. Epub 2008 Mar 21.

Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1016/j.biocel.2008.03.010DOI Listing
September 2008

Should open Kasai portoenterostomy be performed for biliary atresia in the era of laparoscopy?

Pediatr Surg Int 2008 Aug 28;24(8):931-3. Epub 2008 Jun 28.

Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1007/s00383-008-2190-0DOI Listing
August 2008

LPS-induced up-regulation of TGF-beta receptor 1 is associated with TNF-alpha expression in human monocyte-derived macrophages.

J Leukoc Biol 2008 May 5;83(5):1165-73. Epub 2008 Feb 5.

Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, China.

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http://doi.wiley.com/10.1189/jlb.0807521
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http://dx.doi.org/10.1189/jlb.0807521DOI Listing
May 2008

Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation.

Transpl Int 2008 May 4;21(5):483-94. Epub 2008 Feb 4.

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China.

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http://dx.doi.org/10.1111/j.1432-2277.2007.00630.xDOI Listing
May 2008

Hypoxia modulates lipopolysaccharide induced TNF-alpha expression in murine macrophages.

Exp Cell Res 2008 Apr 16;314(6):1327-36. Epub 2008 Jan 16.

Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, PR China.

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http://dx.doi.org/10.1016/j.yexcr.2008.01.007DOI Listing
April 2008

Apoptotic cells protect mice against lipopolysaccharide-induced shock.

J Immunol 2008 Apr;180(7):4978-85

Department of Surgery, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.4049/jimmunol.180.7.4978DOI Listing
April 2008

Suppression of lung tumor growth and metastasis in mice by adeno-associated virus-mediated expression of vasostatin.

Clin Cancer Res 2008 Feb;14(3):939-49

Department of Biochemistry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1930DOI Listing
February 2008

Towards predictive, preventive, and personalized paediatric surgery.

Authors:
Paul K H Tam

J Pediatr Surg 2008 Feb;43(2):267-73

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1016/j.jpedsurg.2007.10.012DOI Listing
February 2008

Triptolide, a component of Chinese herbal medicine, modulates the functional phenotype of dendritic cells.

Transplantation 2007 Dec;84(11):1517-26

Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, PR China.

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http://dx.doi.org/10.1097/01.tp.0000289990.55668.0dDOI Listing
December 2007

Involvement of visinin-like protein-1 (VSNL-1) in regulating proliferative and invasive properties of neuroblastoma.

Carcinogenesis 2007 Oct 5;28(10):2122-30. Epub 2007 Jul 5.

Department of Surgery, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1093/carcin/bgm147DOI Listing
October 2007

A second generation human haplotype map of over 3.1 million SNPs.

Authors:
Kelly A Frazer Dennis G Ballinger David R Cox David A Hinds Laura L Stuve Richard A Gibbs John W Belmont Andrew Boudreau Paul Hardenbol Suzanne M Leal Shiran Pasternak David A Wheeler Thomas D Willis Fuli Yu Huanming Yang Changqing Zeng Yang Gao Haoran Hu Weitao Hu Chaohua Li Wei Lin Siqi Liu Hao Pan Xiaoli Tang Jian Wang Wei Wang Jun Yu Bo Zhang Qingrun Zhang Hongbin Zhao Hui Zhao Jun Zhou Stacey B Gabriel Rachel Barry Brendan Blumenstiel Amy Camargo Matthew Defelice Maura Faggart Mary Goyette Supriya Gupta Jamie Moore Huy Nguyen Robert C Onofrio Melissa Parkin Jessica Roy Erich Stahl Ellen Winchester Liuda Ziaugra David Altshuler Yan Shen Zhijian Yao Wei Huang Xun Chu Yungang He Li Jin Yangfan Liu Yayun Shen Weiwei Sun Haifeng Wang Yi Wang Ying Wang Xiaoyan Xiong Liang Xu Mary M Y Waye Stephen K W Tsui Hong Xue J Tze-Fei Wong Luana M Galver Jian-Bing Fan Kevin Gunderson Sarah S Murray Arnold R Oliphant Mark S Chee Alexandre Montpetit Fanny Chagnon Vincent Ferretti Martin Leboeuf Jean-François Olivier Michael S Phillips Stéphanie Roumy Clémentine Sallée Andrei Verner Thomas J Hudson Pui-Yan Kwok Dongmei Cai Daniel C Koboldt Raymond D Miller Ludmila Pawlikowska Patricia Taillon-Miller Ming Xiao Lap-Chee Tsui William Mak You Qiang Song Paul K H Tam Yusuke Nakamura Takahisa Kawaguchi Takuya Kitamoto Takashi Morizono Atsushi Nagashima Yozo Ohnishi Akihiro Sekine Toshihiro Tanaka Tatsuhiko Tsunoda Panos Deloukas Christine P Bird Marcos Delgado Emmanouil T Dermitzakis Rhian Gwilliam Sarah Hunt Jonathan Morrison Don Powell Barbara E Stranger Pamela Whittaker David R Bentley Mark J Daly Paul I W de Bakker Jeff Barrett Yves R Chretien Julian Maller Steve McCarroll Nick Patterson Itsik Pe'er Alkes Price Shaun Purcell Daniel J Richter Pardis Sabeti Richa Saxena Stephen F Schaffner Pak C Sham Patrick Varilly David Altshuler Lincoln D Stein Lalitha Krishnan Albert Vernon Smith Marcela K Tello-Ruiz Gudmundur A Thorisson Aravinda Chakravarti Peter E Chen David J Cutler Carl S Kashuk Shin Lin Gonçalo R Abecasis Weihua Guan Yun Li Heather M Munro Zhaohui Steve Qin Daryl J Thomas Gilean McVean Adam Auton Leonardo Bottolo Niall Cardin Susana Eyheramendy Colin Freeman Jonathan Marchini Simon Myers Chris Spencer Matthew Stephens Peter Donnelly Lon R Cardon Geraldine Clarke David M Evans Andrew P Morris Bruce S Weir Tatsuhiko Tsunoda James C Mullikin Stephen T Sherry Michael Feolo Andrew Skol Houcan Zhang Changqing Zeng Hui Zhao Ichiro Matsuda Yoshimitsu Fukushima Darryl R Macer Eiko Suda Charles N Rotimi Clement A Adebamowo Ike Ajayi Toyin Aniagwu Patricia A Marshall Chibuzor Nkwodimmah Charmaine D M Royal Mark F Leppert Missy Dixon Andy Peiffer Renzong Qiu Alastair Kent Kazuto Kato Norio Niikawa Isaac F Adewole Bartha M Knoppers Morris W Foster Ellen Wright Clayton Jessica Watkin Richard A Gibbs John W Belmont Donna Muzny Lynne Nazareth Erica Sodergren George M Weinstock David A Wheeler Imtaz Yakub Stacey B Gabriel Robert C Onofrio Daniel J Richter Liuda Ziaugra Bruce W Birren Mark J Daly David Altshuler Richard K Wilson Lucinda L Fulton Jane Rogers John Burton Nigel P Carter Christopher M Clee Mark Griffiths Matthew C Jones Kirsten McLay Robert W Plumb Mark T Ross Sarah K Sims David L Willey Zhu Chen Hua Han Le Kang Martin Godbout John C Wallenburg Paul L'Archevêque Guy Bellemare Koji Saeki Hongguang Wang Daochang An Hongbo Fu Qing Li Zhen Wang Renwu Wang Arthur L Holden Lisa D Brooks Jean E McEwen Mark S Guyer Vivian Ota Wang Jane L Peterson Michael Shi Jack Spiegel Lawrence M Sung Lynn F Zacharia Francis S Collins Karen Kennedy Ruth Jamieson John Stewart

Nature 2007 Oct;449(7164):851-61

The Scripps Research Institute, 10550 North Torrey Pines Road MEM275, La Jolla, California 92037, USA.

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October 2007

Genome-wide detection and characterization of positive selection in human populations.

Authors:
Pardis C Sabeti Patrick Varilly Ben Fry Jason Lohmueller Elizabeth Hostetter Chris Cotsapas Xiaohui Xie Elizabeth H Byrne Steven A McCarroll Rachelle Gaudet Stephen F Schaffner Eric S Lander Kelly A Frazer Dennis G Ballinger David R Cox David A Hinds Laura L Stuve Richard A Gibbs John W Belmont Andrew Boudreau Paul Hardenbol Suzanne M Leal Shiran Pasternak David A Wheeler Thomas D Willis Fuli Yu Huanming Yang Changqing Zeng Yang Gao Haoran Hu Weitao Hu Chaohua Li Wei Lin Siqi Liu Hao Pan Xiaoli Tang Jian Wang Wei Wang Jun Yu Bo Zhang Qingrun Zhang Hongbin Zhao Hui Zhao Jun Zhou Stacey B Gabriel Rachel Barry Brendan Blumenstiel Amy Camargo Matthew Defelice Maura Faggart Mary Goyette Supriya Gupta Jamie Moore Huy Nguyen Robert C Onofrio Melissa Parkin Jessica Roy Erich Stahl Ellen Winchester Liuda Ziaugra David Altshuler Yan Shen Zhijian Yao Wei Huang Xun Chu Yungang He Li Jin Yangfan Liu Yayun Shen Weiwei Sun Haifeng Wang Yi Wang Ying Wang Xiaoyan Xiong Liang Xu Mary M Y Waye Stephen K W Tsui Hong Xue J Tze-Fei Wong Luana M Galver Jian-Bing Fan Kevin Gunderson Sarah S Murray Arnold R Oliphant Mark S Chee Alexandre Montpetit Fanny Chagnon Vincent Ferretti Martin Leboeuf Jean-François Olivier Michael S Phillips Stéphanie Roumy Clémentine Sallée Andrei Verner Thomas J Hudson Pui-Yan Kwok Dongmei Cai Daniel C Koboldt Raymond D Miller Ludmila Pawlikowska Patricia Taillon-Miller Ming Xiao Lap-Chee Tsui William Mak You Qiang Song Paul K H Tam Yusuke Nakamura Takahisa Kawaguchi Takuya Kitamoto Takashi Morizono Atsushi Nagashima Yozo Ohnishi Akihiro Sekine Toshihiro Tanaka Tatsuhiko Tsunoda Panos Deloukas Christine P Bird Marcos Delgado Emmanouil T Dermitzakis Rhian Gwilliam Sarah Hunt Jonathan Morrison Don Powell Barbara E Stranger Pamela Whittaker David R Bentley Mark J Daly Paul I W de Bakker Jeff Barrett Yves R Chretien Julian Maller Steve McCarroll Nick Patterson Itsik Pe'er Alkes Price Shaun Purcell Daniel J Richter Pardis Sabeti Richa Saxena Stephen F Schaffner Pak C Sham Patrick Varilly David Altshuler Lincoln D Stein Lalitha Krishnan Albert Vernon Smith Marcela K Tello-Ruiz Gudmundur A Thorisson Aravinda Chakravarti Peter E Chen David J Cutler Carl S Kashuk Shin Lin Gonçalo R Abecasis Weihua Guan Yun Li Heather M Munro Zhaohui Steve Qin Daryl J Thomas Gilean McVean Adam Auton Leonardo Bottolo Niall Cardin Susana Eyheramendy Colin Freeman Jonathan Marchini Simon Myers Chris Spencer Matthew Stephens Peter Donnelly Lon R Cardon Geraldine Clarke David M Evans Andrew P Morris Bruce S Weir Tatsuhiko Tsunoda Todd A Johnson James C Mullikin Stephen T Sherry Michael Feolo Andrew Skol Houcan Zhang Changqing Zeng Hui Zhao Ichiro Matsuda Yoshimitsu Fukushima Darryl R Macer Eiko Suda Charles N Rotimi Clement A Adebamowo Ike Ajayi Toyin Aniagwu Patricia A Marshall Chibuzor Nkwodimmah Charmaine D M Royal Mark F Leppert Missy Dixon Andy Peiffer Renzong Qiu Alastair Kent Kazuto Kato Norio Niikawa Isaac F Adewole Bartha M Knoppers Morris W Foster Ellen Wright Clayton Jessica Watkin Richard A Gibbs John W Belmont Donna Muzny Lynne Nazareth Erica Sodergren George M Weinstock David A Wheeler Imtaz Yakub Stacey B Gabriel Robert C Onofrio Daniel J Richter Liuda Ziaugra Bruce W Birren Mark J Daly David Altshuler Richard K Wilson Lucinda L Fulton Jane Rogers John Burton Nigel P Carter Christopher M Clee Mark Griffiths Matthew C Jones Kirsten McLay Robert W Plumb Mark T Ross Sarah K Sims David L Willey Zhu Chen Hua Han Le Kang Martin Godbout John C Wallenburg Paul L'Archevêque Guy Bellemare Koji Saeki Hongguang Wang Daochang An Hongbo Fu Qing Li Zhen Wang Renwu Wang Arthur L Holden Lisa D Brooks Jean E McEwen Mark S Guyer Vivian Ota Wang Jane L Peterson Michael Shi Jack Spiegel Lawrence M Sung Lynn F Zacharia Francis S Collins Karen Kennedy Ruth Jamieson John Stewart

Nature 2007 Oct;449(7164):913-8

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA.

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October 2007

Increased iNOS-expressing macrophage in long-term surviving rat small-bowel grafts.

Am J Surg 2007 Aug;194(2):248-54

Division of Pediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, PRC.

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August 2007

Rosiglitazone suppresses cyclosporin-induced chronic transplant dysfunction and prolongs survival of rat cardiac allografts.

Transplantation 2007 Jun;83(12):1602-10

Department of Surgery, Faculty of Medicine Building, University of Hong Kong, Pokfulam, Hong Kong, SAR China.

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June 2007

Inhibition of sonic hedgehog signaling reduces chronic rejection and prolongs allograft survival in a rat orthotopic small bowel transplantation model.

Transplantation 2007 May;83(10):1351-7

Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, PR China.

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May 2007

Prokineticin-1 modulates proliferation and differentiation of enteric neural crest cells.

Biochim Biophys Acta 2007 Apr 2;1773(4):536-45. Epub 2007 Feb 2.

Department of Surgery, University of Hong Kong, Pokfulam, Faculty of Medicine Building, 21 Sassoon Road, Hong Kong, SAR, China.

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April 2007

Application of HapMap data to the evaluation of 8 candidate genes for pediatric slow transit constipation.

J Pediatr Surg 2007 Apr;42(4):666-71

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Hong Kong SAR, China.

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April 2007

Spontaneous pneumoperitoneum after pneumonia in a child.

J Paediatr Child Health 2007 Jan-Feb;43(1-2):85-6

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, China.

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March 2007

Implications of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 signaling in human neuroblastoma progression.

Clin Cancer Res 2007 Feb;13(3):868-75

Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, SAR, China, and Department of Pediatric Surgery, The Second Affiliated Hospital of China Medical University, Shenyang, China.

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February 2007

Topical delivery of silver nanoparticles promotes wound healing.

ChemMedChem 2007 Jan;2(1):129-36

Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/cmdc.200600171DOI Listing
January 2007

Sonic hedgehog promotes CD4+ T lymphocyte proliferation and modulates the expression of a subset of CD28-targeted genes.

Int Immunol 2006 Dec 27;18(12):1627-36. Epub 2006 Sep 27.

Department of Surgery, University of Hong Kong Medical Centre, K-15 Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1093/intimm/dxl096DOI Listing
December 2006

Selective upper endoscopy for foreign body ingestion in children: an evaluation of management protocol after 282 cases.

J Pediatr Surg 2006 Dec;41(12):2016-8

Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong, SAR, China.

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December 2006

Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection.

Nat Genet 2006 Jan 20;38(1):38-46. Epub 2005 Dec 20.

Department of Surgery, Hong Kong Jockey Club Clinical Research Center, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, SAR, China.

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January 2006

Removing intensity effects and identifying significant genes for Affymetrix arrays in macrophage migration inhibitory factor-suppressed neuroblastoma cells.

Proc Natl Acad Sci U S A 2005 Dec 28;102(49):17751-6. Epub 2005 Nov 28.

Department of Operation Research and Financial Engineering, Princeton University, Princeton, NJ 08544, USA.

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December 2005

Trends in the prevalence of Helicobacter pylori in symptomatic children in the era of eradication.

J Pediatr Surg 2005 Dec;40(12):1844-7

Department of Surgery, Queen Mary Hospital, University of Hong Kong Medical Centre, Hong Kong SAR, China.

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December 2005

Serological protein profiling of neuroblastoma by ProteinChip SELDI-TOF technology.

J Cell Biochem 2005 May;95(1):165-72

Department of Chemistry, University of Hong Kong, Pokfulam, Hong Kong, China.

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May 2005

Altered expression of aquaporin-2 in human explants with chronic renal allograft dysfunction.

BJU Int 2005 May;95(7):1104-8

Department of Surgery, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR, China.

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May 2005

TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease.

Hum Mol Genet 2005 Jan 17;14(2):191-204. Epub 2004 Nov 17.

Department of Surgery, The University of Hong Kong, Hong Kong SAR, China.

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January 2005

The use of positron emission tomography in detecting hepatoblastoma recurrence--a cautionary tale.

J Pediatr Surg 2004 Dec;39(12):1779-81

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, People's Republic of China.

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December 2004

Effective antibiotic regime for postoperative acute cholangitis in biliary atresia--an evolving scene.

J Pediatr Surg 2004 Dec;39(12):1800-2

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, People's Republic of China.

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December 2004

Molecular genetics of Hirschsprung's disease.

Semin Pediatr Surg 2004 Nov;13(4):236-48

Department of Surgery and Genome Research Centre, The University of Hong Kong, Queen Mary Hospital K15, Pokfulam, Hong Kong, P.R. China.

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November 2004

Mucous fistula refeeding in premature neonates with enterostomies.

J Pediatr Gastroenterol Nutr 2004 Jul;39(1):43-5

Division of Paediatric Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China.

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July 2004

Ubiquitous aberrant RASSF1A promoter methylation in childhood neoplasia.

Clin Cancer Res 2004 Feb;10(3):994-1002

Department of Biochemistry, 3/F Laboratory Block, Faculty of Medicine Building, 21 Sassoon Road, The University of Hong Kong, Hong Kong Special Administrative Region.

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February 2004

Portoenterostomy for biliary atresia: Long-term survival and prognosis after esophageal variceal bleeding.

J Pediatr Surg 2004 Jan;39(1):6-9

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, SAR, People's Republic of China.

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January 2004

Double intestinal atresia in imperforate anus: a diagnostic conundrum for paediatric surgeons.

Asian J Surg 2004 Jan;27(1):52-3

Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong.

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January 2004

Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery.

Transplantation 2004 Jan;77(2):183-9

Division of Paediatric Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, People's Republic of China.

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January 2004

A safe laparoscopic technique for the repair of inguinal hernias in boys.

J Am Coll Surg 2003 Jun;196(6):987-9

Division of Pediatric Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, China.

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June 2003

Mammary gland-specific secretion of biologically active immunosuppressive agent cytotoxic-T-lymphocyte antigen 4 human immunoglobulin fusion protein (CTLA4Ig) in milk by transgenesis.

J Immunol Methods 2003 Jun;277(1-2):171-83

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, SAR, Hong Kong, China.

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http://dx.doi.org/10.1016/s0022-1759(03)00071-1DOI Listing
June 2003

Comparative study of allograft survival of heterotopic and orthotopic small bowel transplantation in rat.

Transplantation 2003 Jun;75(11):1895-7

Division of Paediatric Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, P.R. China.

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http://dx.doi.org/10.1097/01.TP.0000065294.04793.11DOI Listing
June 2003

Cholangitis after hepatic portoenterostomy for biliary atresia: a multivariate analysis of risk factors.

J Pediatr 2003 May;142(5):566-71

Division of Paediatric Surgery, Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, China.

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May 2003