Paul Greengard

Paul Greengard

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Paul Greengard

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Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons.

Cell Stem Cell 2019 Oct 19;25(4):514-530.e8. Epub 2019 Sep 19.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.stem.2019.08.013DOI Listing
October 2019

Correction: Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice.

Mol Psychiatry 2019 Sep 13. Epub 2019 Sep 13.

Department of Physiology and Biophysics, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY, 14203, USA.

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http://dx.doi.org/10.1038/s41380-019-0524-zDOI Listing
September 2019

Cholinergic Neurons of the Medial Septum Are Crucial for Sensorimotor Gating.

J Neurosci 2019 Jun 26;39(26):5234-5242. Epub 2019 Apr 26.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10065

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http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.0950-1
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http://dx.doi.org/10.1523/JNEUROSCI.0950-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595952PMC
June 2019

A Role of Drd2 Hippocampal Neurons in Context-Dependent Food Intake.

Neuron 2019 May 28;102(4):873-886.e5. Epub 2019 Mar 28.

Laboratory of Molecular Genetics, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.03.011DOI Listing
May 2019

Hippocampal mossy cell involvement in behavioral and neurogenic responses to chronic antidepressant treatment.

Mol Psychiatry 2019 Mar 5. Epub 2019 Mar 5.

Department of Brain-Cognitive Science, Daegu-Gyeongbuk Institute of Science and Technology (DGIST), Hyenpung-myeon, Dalseong-gun, Daegu, Republic of Korea.

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http://dx.doi.org/10.1038/s41380-019-0384-6DOI Listing
March 2019

GSAP modulates γ-secretase specificity by inducing conformational change in PS1.

Proc Natl Acad Sci U S A 2019 03 8;116(13):6385-6390. Epub 2019 Mar 8.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1820160116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442608PMC
March 2019

HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors.

Neuron 2019 02 10;101(4):662-672.e5. Epub 2019 Jan 10.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273183111
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http://dx.doi.org/10.1016/j.neuron.2018.12.018DOI Listing
February 2019

Emergence of 5-HT5A signaling in parvalbumin neurons mediates delayed antidepressant action.

Mol Psychiatry 2019 Feb 25. Epub 2019 Feb 25.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY, USA.

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http://dx.doi.org/10.1038/s41380-019-0379-3DOI Listing
February 2019

Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice.

Mol Psychiatry 2019 Jan 18. Epub 2019 Jan 18.

Department of Physiology and Biophysics, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY, 14203, USA.

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http://dx.doi.org/10.1038/s41380-019-0351-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639159PMC
January 2019

CK1δ over-expressing mice display ADHD-like behaviors, frontostriatal neuronal abnormalities and altered expressions of ADHD-candidate genes.

Mol Psychiatry 2018 Oct 19. Epub 2018 Oct 19.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.

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http://dx.doi.org/10.1038/s41380-018-0233-zDOI Listing
October 2018

Reactive Dopamine Leads to Triple Trouble in Nigral Neurons.

Biochemistry 2017 12 30;56(49):6409-6410. Epub 2017 Nov 30.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University , 1230 York Avenue, New York, New York 10065, United States.

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http://dx.doi.org/10.1021/acs.biochem.7b01057DOI Listing
December 2017

Building Bridges through Science.

Authors:
Thomas Lissek Michelle Adams John Adelman Ehud Ahissar Mohammed Akaaboune Huda Akil Mustafa al'Absi Fazal Arain Juan Carlos Arango-Lasprilla Deniz Atasoy Jesus Avila Ashraf Badawi Hilmar Bading Abdul Mannan Baig Jimena Baleriola Carlos Belmonte Ilaria Bertocchi Heinrich Betz Colin Blakemore Olaf Blanke Philipp Boehm-Sturm Tobias Bonhoeffer Paolo Bonifazi Nils Brose Patrizia Campolongo Tansu Celikel Cathy C Chang Ta-Yuan Chang Ami Citri Hollis T Cline Jesus M Cortes Kathleen Cullen Kellie Dean José M Delgado-Garcia Mathieu Desroches John F Disterhoft John E Dowling Andreas Draguhn Sherif F El-Khamisy Abdeljabbar El Manira S Ather Enam Juan M Encinas Asier Erramuzpe José A Esteban Isabel Fariñas Edmond Fischer Izumi Fukunaga Iñigo Gabilondo Detlev Ganten Albert Gidon Juan Carlos Gomez-Esteban Paul Greengard Valery Grinevich Agnés Gruart Roger Guillemin Ahmad R Hariri Bassem Hassan Michael Häusser Yasunori Hayashi Natasha K Hussain Adnan Abdul Jabbar Mohamed Jaber Reinhardt Jahn Essam Mohammed Janahi Mohamed Kabbaj Helmut Kettenmann Merel Kindt Shira Knafo Georg Köhr Shoji Komai Harm Krugers Bernd Kuhn Nouria Lakhdar Ghazal Matthew E Larkum Mickey London Beat Lutz Carlos Matute Luis Martinez-Millan Mouna Maroun James McGaugh Ahmed A Moustafa Anwar Nasim Klaus-Armin Nave Erwin Neher Karoly Nikolich Tiago Outeiro Lucy M Palmer Olga Penagarikano Isabel Perez-Otano Donald W Pfaff Bruno Poucet Atta-Ur Rahman Pedro Ramos-Cabrer Ali Rashidy-Pour Richard J Roberts Serafim Rodrigues Joshua R Sanes Andreas T Schaefer Menahem Segal Idan Segev Saad Shafqat Nikhat Ahmed Siddiqui Hermona Soreq Eduardo Soriano-García Rainer Spanagel Rolf Sprengel Greg Stuart Thomas C Südhof Jan Tønnesen Mario Treviño Basim M Uthman J Craig Venter Alexei Verkhratsky Craig Weiss Torsten N Wiesel Emre Yaksi Ofer Yizhar Larry J Young Paul Young Nasser H Zawia José L Zugaza Mazahir T Hasan

Neuron 2017 Nov;96(4):730-735

Achucarro Basque Center for Neuroscience, 48940 Leioa, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.09.028DOI Listing
November 2017

Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements.

Nat Commun 2017 09 20;8(1):623. Epub 2017 Sep 20.

Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.

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http://dx.doi.org/10.1038/s41467-017-00353-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606996PMC
September 2017

Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus.

Neuron 2017 Aug 20;95(3):564-576.e4. Epub 2017 Jul 20.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.06.044DOI Listing
August 2017

Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion.

Proc Natl Acad Sci U S A 2017 07 22;114(27):7148-7153. Epub 2017 May 22.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1705240114
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http://dx.doi.org/10.1073/pnas.1705240114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502640PMC
July 2017

Bidirectional regulation of Aβ levels by Presenilin 1.

Proc Natl Acad Sci U S A 2017 07 22;114(27):7142-7147. Epub 2017 May 22.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1705235114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502639PMC
July 2017

Cell- and region-specific expression of depression-related protein p11 (S100a10) in the brain.

J Comp Neurol 2017 Mar 21;525(4):955-975. Epub 2016 Oct 21.

Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1002/cne.24113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222728PMC
March 2017

Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson's disease.

Proc Natl Acad Sci U S A 2017 03 30;114(10):2735-2740. Epub 2017 Jan 30.

Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institute, SE-171 76 Stockholm, Sweden;

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http://dx.doi.org/10.1073/pnas.1621218114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347629PMC
March 2017

WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine.

Proc Natl Acad Sci U S A 2017 02 23;114(6):1395-1400. Epub 2017 Jan 23.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1621185114
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http://dx.doi.org/10.1073/pnas.1621185114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307471PMC
February 2017

Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage.

Proc Natl Acad Sci U S A 2017 02 23;114(6):1389-1394. Epub 2017 Jan 23.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065.

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http://dx.doi.org/10.1073/pnas.1620963114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307477PMC
February 2017

Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice.

Synapse 2016 07 4;70(7):293-301. Epub 2016 May 4.

Laboratory of Neuroimaging, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/syn.21904DOI Listing
July 2016

Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method.

Cell Rep 2016 07 14;16(4):1138-1152. Epub 2016 Jul 14.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.06.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040352PMC
July 2016

δ-COP modulates Aβ peptide formation via retrograde trafficking of APP.

Proc Natl Acad Sci U S A 2016 May 25;113(19):5412-7. Epub 2016 Apr 25.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065

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http://dx.doi.org/10.1073/pnas.1604156113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868462PMC
May 2016

Relevance of the COPI complex for Alzheimer's disease progression in vivo.

Proc Natl Acad Sci U S A 2016 May 25;113(19):5418-23. Epub 2016 Apr 25.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1604176113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868486PMC
May 2016

p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism.

Proc Natl Acad Sci U S A 2016 Feb 19;113(5):1429-34. Epub 2016 Jan 19.

Translational Neuropharmacology, Department of Clinical Neuroscience, Center for Molecular Medicine L8:01, Karolinska Institute, 171 76 Stockholm, Sweden;

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http://dx.doi.org/10.1073/pnas.1524303113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747690PMC
February 2016

Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice.

Proc Natl Acad Sci U S A 2016 Feb 19;113(5):1423-8. Epub 2016 Jan 19.

Laboratory of Molecular Neurosurgery, Department of Neurological Surgery, Weill Cornell Medical College, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1524387113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747714PMC
February 2016

Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum.

Proc Natl Acad Sci U S A 2016 Jan 5;113(3):734-9. Epub 2016 Jan 5.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1524183113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725497PMC
January 2016

Hypothalamic Amylin Acts in Concert with Leptin to Regulate Food Intake.

Cell Metab 2015 Dec 19;22(6):1059-67. Epub 2015 Nov 19.

Laboratory of Molecular Genetics, The Rockefeller University, New York, NY 10065, USA; Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, MD 20815-6789, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.10.012DOI Listing
December 2015

Role of Dopamine Type 1 Receptors and Dopamine- and cAMP-Regulated Phosphoprotein Mr 32 kDa in Δ9-Tetrahydrocannabinol-Mediated Induction of ΔFosB in the Mouse Forebrain.

J Pharmacol Exp Ther 2015 Sep 22;354(3):316-27. Epub 2015 Jun 22.

Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia (M.F.L., A.J.T., A.H.L., D.E.S., L.J.S.-S.); and Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, New York (P.G., M.F.)

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http://dx.doi.org/10.1124/jpet.115.224428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538878PMC
September 2015

Identification of neurodegenerative factors using translatome-regulatory network analysis.

Nat Neurosci 2015 Sep 27;18(9):1325-33. Epub 2015 Jul 27.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1038/nn.4070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763340PMC
September 2015

APP intracellular domain-WAVE1 pathway reduces amyloid-β production.

Nat Med 2015 Sep 17;21(9):1054-9. Epub 2015 Aug 17.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA.

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http://www.nature.com/articles/nm.3924
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http://dx.doi.org/10.1038/nm.3924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560977PMC
September 2015

The role of ventral striatal cAMP signaling in stress-induced behaviors.

Nat Neurosci 2015 Aug 20;18(8):1094-100. Epub 2015 Jul 20.

1] Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas, USA. [2] Department of Neurology and Neurotherapeutics, The University of Texas Southwestern Medical Center, Dallas, Texas, USA. [3] Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/nn.4066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519694PMC
August 2015

Norbin ablation results in defective adult hippocampal neurogenesis and depressive-like behavior in mice.

Proc Natl Acad Sci U S A 2015 Aug 20;112(31):9745-50. Epub 2015 Jul 20.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1510291112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534263PMC
August 2015

Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function.

J Neurochem 2015 Mar 4;132(6):677-86. Epub 2015 Mar 4.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA; Department of Pharmacology, Kurume University School of Medicine, Kurume, Fukuoka, Japan; Department of Psychiatry, Kurume University School of Medicine, Kurume, Fukuoka, Japan; Cognitive and Molecular Research Institute of Brain Diseases, Kurume University, Kurume, Fukuoka, Japan.

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http://dx.doi.org/10.1111/jnc.13038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359654PMC
March 2015

Molecular determinants of selective dopaminergic vulnerability in Parkinson's disease: an update.

Front Neuroanat 2014 15;8:152. Epub 2014 Dec 15.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University New York, NY, USA.

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http://dx.doi.org/10.3389/fnana.2014.00152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266033PMC
January 2015

Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP).

Nat Protoc 2014 8;9(6):1282-91. Epub 2014 May 8.

Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1038/nprot.2014.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102313PMC
December 2014

Nitric oxide regulates synaptic transmission between spiny projection neurons.

Proc Natl Acad Sci U S A 2014 Dec 20;111(49):17636-41. Epub 2014 Nov 20.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1420162111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267338PMC
December 2014

Cell-type specific expression of p11 controls cocaine reward.

Biol Psychiatry 2014 Nov 26;76(10):794-801. Epub 2014 Feb 26.

Fishberg Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145045PMC
November 2014

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia.

Nat Commun 2014 Oct 31;5:5316. Epub 2014 Oct 31.

Department of Physiology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/ncomms6316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431763PMC
October 2014

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.

PLoS Biol 2014 Aug 5;12(8):e1001923. Epub 2014 Aug 5.

Child Study Center, Yale University, New Haven, Connecticut, United States of America; Department of Psychiatry, Yale University, New Haven, Connecticut, United States of America; Department of Neurobiology, Yale University, New Haven, Connecticut, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1001923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122355PMC
August 2014

The convergence of endosomal and autophagosomal pathways: implications for APP-CTF degradation.

Autophagy 2014 Apr 16;10(4):694-6. Epub 2014 Jan 16.

Laboratory of Molecular and Cellular Neuroscience; Rockefeller University; New York, NY USA.

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http://dx.doi.org/10.4161/auto.27802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091156PMC
April 2014

Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia.

Proc Natl Acad Sci U S A 2014 Mar 5;111(12):4578-83. Epub 2014 Mar 5.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065.

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http://dx.doi.org/10.1073/pnas.1401819111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970487PMC
March 2014

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.

Proc Natl Acad Sci U S A 2013 Oct 25;110(42):17071-6. Epub 2013 Sep 25.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065.

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http://dx.doi.org/10.1073/pnas.1315110110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801056PMC
October 2013

Advances in the pharmacological treatment of Parkinson's disease: targeting neurotransmitter systems.

Trends Neurosci 2013 Sep 19;36(9):543-54. Epub 2013 Jul 19.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2013.06.003DOI Listing
September 2013

Selective knockout of the casein kinase 2 in d1 medium spiny neurons controls dopaminergic function.

Biol Psychiatry 2013 Jul 3;74(2):113-21. Epub 2013 Jan 3.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.biopsych.2012.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878430PMC
July 2013

A conversation with Paul Greengard. Interview by Eric J Nestler.

Authors:
Paul Greengard

Annu Rev Pharmacol Toxicol 2013 ;53:1-16

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http://dx.doi.org/10.1146/annurev-pharmtox-062712-160347DOI Listing
July 2013

Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons.

Proc Natl Acad Sci U S A 2013 Jun 20;110(23):9511-6. Epub 2013 May 20.

Unité Mixte de Recherche en Santé 839, Institut National de la Santé et de la Recherche Médicale, 75005 Paris, France.

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http://dx.doi.org/10.1073/pnas.1307116110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677456PMC
June 2013

A conversation with Paul Greengard. Interview by Ushma S. Neill.

Authors:
Paul Greengard

J Clin Invest 2013 Mar 1;123(3):937-8. Epub 2013 Mar 1.

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http://dx.doi.org/10.1172/JCI68877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582157PMC
March 2013

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.

FASEB J 2012 Dec 12;26(12):5115-23. Epub 2012 Sep 12.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Ave., New York, NY 10021, USA.

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http://dx.doi.org/10.1096/fj.12-212985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509055PMC
December 2012

Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior.

Proc Natl Acad Sci U S A 2012 Jul 25;109(28):11360-5. Epub 2012 Jun 25.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.1209293109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396525PMC
July 2012

Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex.

Psychopharmacology (Berl) 2012 Feb 11;219(4):1065-79. Epub 2011 Aug 11.

Department of Pharmacology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan.

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http://dx.doi.org/10.1007/s00213-011-2436-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539205PMC
February 2012

Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine.

J Neurosci 2012 Feb;32(8):2683-95

Department of Physiology and Biophysics, Genetics, University of Alabama, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4125-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310383PMC
February 2012

Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits.

Eur J Neurosci 2012 Jan;35(2):300-8

Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06508, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2011.07956.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622044PMC
January 2012

Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization.

J Neurochem 2011 Nov 21;119(3):664-72. Epub 2011 Sep 21.

Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07450.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192910PMC
November 2011

Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases.

Front Neuroanat 2011 26;5:50. Epub 2011 Aug 26.

Department of Biochemistry, Institute of Basic Medical Sciences, University of Oslo Oslo, Norway.

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http://dx.doi.org/10.3389/fnana.2011.00050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162284PMC
November 2011

Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum.

Neuropharmacology 2011 Sep 12;61(3):442-50. Epub 2011 Feb 12.

Center for Molecular Medicine, Karolinska Institute, 17176, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.neuropharm.2011.01.046DOI Listing
September 2011

A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.

FASEB J 2011 Jun 2;25(6):1934-42. Epub 2011 Mar 2.

Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, 1230 York Ave., New York, NY 10065, USA.

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http://www.fasebj.org/doi/10.1096/fj.10-175158
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http://dx.doi.org/10.1096/fj.10-175158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101026PMC
June 2011

Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans.

Proc Natl Acad Sci U S A 2011 May 25;108(22):9262-7. Epub 2011 Apr 25.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.1104836108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107316PMC
May 2011

Epigenetic mechanisms of mental retardation.

Prog Drug Res 2011 ;67:125-46

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

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January 2011

Norbin: A promising central nervous system regulator.

Commun Integr Biol 2010 Nov 1;3(6):487-90. Epub 2010 Nov 1.

Laboratory of Molecular and Cellular Neuroscience; The Rockefeller University; New York, NY USA.

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http://dx.doi.org/10.4161/cib.3.6.12844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038045PMC
November 2010

Kinetics of G-protein-coupled receptor endosomal trafficking pathways revealed by single quantum dots.

Proc Natl Acad Sci U S A 2010 Oct 12;107(43):18658-63. Epub 2010 Oct 12.

Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1073/pnas.1013763107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972942PMC
October 2010

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.

Nature 2010 Sep;467(7311):95-8

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nature09325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936959PMC
September 2010

Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.

J Exp Med 2010 Aug 19;207(9):1843-51. Epub 2010 Jul 19.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1084/jem.20100451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931161PMC
August 2010

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

EMBO J 2010 Aug 27;29(16):2813-26. Epub 2010 Jul 27.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1038/emboj.2010.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924642PMC
August 2010

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors.

Proc Natl Acad Sci U S A 2010 Aug 3;107(33):14845-50. Epub 2010 Aug 3.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.1009874107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930415PMC
August 2010

Positively active: how local anesthetics work.

Anesthesiology 2010 Jul;113(1):250-2

Department of Anesthesiology, Weill Cornell Medical College, New York, New York, USA.

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July 2010

Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model.

PLoS One 2010 Jun 3;5(6):e10943. Epub 2010 Jun 3.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010943PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880593PMC
June 2010