Paul Goodfellow

Paul Goodfellow

UNVERIFIED PROFILE

Are you Paul Goodfellow?   Register this Author

Register author
Paul Goodfellow

Paul Goodfellow

Publications by authors named "Paul Goodfellow"

Are you Paul Goodfellow?   Register this Author

100Publications

2341Reads

25Profile Views

Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination.

Cancer Res 2019 May 26;79(10):2662-2668. Epub 2019 Mar 26.

Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-18-2460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522273PMC
May 2019

Mismatch repair deficiency identifies patients with high-intermediate-risk (HIR) endometrioid endometrial cancer at the highest risk of recurrence: A prognostic biomarker.

Cancer 2019 Feb 18;125(3):398-405. Epub 2018 Dec 18.

Division of Gynecologic Oncology, Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.31901DOI Listing
February 2019

Diverse mutational signatures in endometrial cancer: implications for tumor etiology and evolution.

Gynecol Oncol 2019 01;152(1):1-2

Division of Gynecologic Oncology, James Comprehensive Cancer Center, The Ohio State University, Columbus, OH. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2018.12.004DOI Listing
January 2019

Functional characterization of recurrent FOXA2 mutations seen in endometrial cancers.

Int J Cancer 2018 12 29;143(11):2955-2961. Epub 2018 Sep 29.

Division of Gynecologic Oncology, James Comprehensive Cancer Center at The Ohio State University, Columbus, OH.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.31784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235715PMC
December 2018

Endometrial cancer: Molecular markers and management of advanced stage disease.

Gynecol Oncol 2018 09 27;150(3):569-580. Epub 2018 May 27.

Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2018.05.015DOI Listing
September 2018

Levels Serve as "Early Signature" Genes in the Development of High-Grade Serous Carcinoma from the Fallopian Tube.

Cancer Res 2018 04 16;78(7):1739-1750. Epub 2018 Jan 16.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-17-1671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907493PMC
April 2018

The FOXA2 transcription factor is frequently somatically mutated in uterine carcinosarcomas and carcinomas.

Cancer 2018 01 21;124(1):65-73. Epub 2017 Sep 21.

Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.30971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735010PMC
January 2018

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Authors:
Roger L Milne Karoline B Kuchenbaecker Kyriaki Michailidou Jonathan Beesley Siddhartha Kar Sara Lindström Shirley Hui Audrey Lemaçon Penny Soucy Joe Dennis Xia Jiang Asha Rostamianfar Hilary Finucane Manjeet K Bolla Lesley McGuffog Qin Wang Cora M Aalfs Marcia Adams Julian Adlard Simona Agata Shahana Ahmed Habibul Ahsan Kristiina Aittomäki Fares Al-Ejeh Jamie Allen Christine B Ambrosone Christopher I Amos Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Norbert Arnold Kristan J Aronson Bernd Auber Paul L Auer Margreet G E M Ausems Jacopo Azzollini François Bacot Judith Balmaña Monica Barile Laure Barjhoux Rosa B Barkardottir Myrto Barrdahl Daniel Barnes Daniel Barrowdale Caroline Baynes Matthias W Beckmann Javier Benitez Marina Bermisheva Leslie Bernstein Yves-Jean Bignon Kathleen R Blazer Marinus J Blok Carl Blomqvist William Blot Kristie Bobolis Bram Boeckx Natalia V Bogdanova Anders Bojesen Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Aniko Bozsik Angela R Bradbury Judith S Brand Hiltrud Brauch Hermann Brenner Brigitte Bressac-de Paillerets Carole Brewer Louise Brinton Per Broberg Angela Brooks-Wilson Joan Brunet Thomas Brüning Barbara Burwinkel Saundra S Buys Jinyoung Byun Qiuyin Cai Trinidad Caldés Maria A Caligo Ian Campbell Federico Canzian Olivier Caron Angel Carracedo Brian D Carter J Esteban Castelao Laurent Castera Virginie Caux-Moncoutier Salina B Chan Jenny Chang-Claude Stephen J Chanock Xiaoqing Chen Ting-Yuan David Cheng Jocelyne Chiquette Hans Christiansen Kathleen B M Claes Christine L Clarke Thomas Conner Don M Conroy Jackie Cook Emilie Cordina-Duverger Sten Cornelissen Isabelle Coupier Angela Cox David G Cox Simon S Cross Katarina Cuk Julie M Cunningham Kamila Czene Mary B Daly Francesca Damiola Hatef Darabi Rosemarie Davidson Kim De Leeneer Peter Devilee Ed Dicks Orland Diez Yuan Chun Ding Nina Ditsch Kimberly F Doheny Susan M Domchek Cecilia M Dorfling Thilo Dörk Isabel Dos-Santos-Silva Stéphane Dubois Pierre-Antoine Dugué Martine Dumont Alison M Dunning Lorraine Durcan Miriam Dwek Bernd Dworniczak Diana Eccles Ros Eeles Hans Ehrencrona Ursula Eilber Bent Ejlertsen Arif B Ekici A Heather Eliassen Christoph Engel Mikael Eriksson Laura Fachal Laurence Faivre Peter A Fasching Ulrike Faust Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger William D Foulkes Eitan Friedman Lin Fritschi Debra Frost Marike Gabrielson Pragna Gaddam Marilie D Gammon Patricia A Ganz Susan M Gapstur Judy Garber Vanesa Garcia-Barberan José A García-Sáenz Mia M Gaudet Marion Gauthier-Villars Andrea Gehrig Vassilios Georgoulias Anne-Marie Gerdes Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Paul Goodfellow Mark H Greene Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Daphne Gschwantler-Kaulich Pascal Guénel Qi Guo Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Emily Hallberg Ute Hamann Nathalie Hamel Susan Hankinson Thomas V O Hansen Patricia Harrington Steven N Hart Jaana M Hartikainen Catherine S Healey Alexander Hein Sonja Helbig Alex Henderson Jane Heyworth Belynda Hicks Peter Hillemanns Shirley Hodgson Frans B Hogervorst Antoinette Hollestelle Maartje J Hooning Bob Hoover John L Hopper Chunling Hu Guanmengqian Huang Peter J Hulick Keith Humphreys David J Hunter Evgeny N Imyanitov Claudine Isaacs Motoki Iwasaki Louise Izatt Anna Jakubowska Paul James Ramunas Janavicius Wolfgang Janni Uffe Birk Jensen Esther M John Nichola Johnson Kristine Jones Michael Jones Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Daehee Kang Karin Kast Renske Keeman Michael J Kerin Carolien M Kets Machteld Keupers Sofia Khan Elza Khusnutdinova Johanna I Kiiski Sung-Won Kim Julia A Knight Irene Konstantopoulou Veli-Matti Kosma Vessela N Kristensen Torben A Kruse Ava Kwong Anne-Vibeke Lænkholm Yael Laitman Fiona Lalloo Diether Lambrechts Keren Landsman Christine Lasset Conxi Lazaro Loic Le Marchand Julie Lecarpentier Andrew Lee Eunjung Lee Jong Won Lee Min Hyuk Lee Flavio Lejbkowicz Fabienne Lesueur Jingmei Li Jenna Lilyquist Anne Lincoln Annika Lindblom Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jennifer T Loud Jan Lubinski Craig Luccarini Michael Lush Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Kathleen E Malone Siranoush Manoukian JoAnn E Manson Sara Margolin John W M Martens Maria Elena Martinez Keitaro Matsuo Dimitrios Mavroudis Sylvie Mazoyer Catriona McLean Hanne Meijers-Heijboer Primitiva Menéndez Jeffery Meyer Hui Miao Austin Miller Nicola Miller Gillian Mitchell Marco Montagna Kenneth Muir Anna Marie Mulligan Claire Mulot Sue Nadesan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Ines Nevelsteen Dieter Niederacher Sune F Nielsen Børge G Nordestgaard Aaron Norman Robert L Nussbaum Edith Olah Olufunmilayo I Olopade Janet E Olson Curtis Olswold Kai-Ren Ong Jan C Oosterwijk Nick Orr Ana Osorio V Shane Pankratz Laura Papi Tjoung-Won Park-Simon Ylva Paulsson-Karlsson Rachel Lloyd Inge Søkilde Pedersen Bernard Peissel Ana Peixoto Jose I A Perez Paolo Peterlongo Julian Peto Georg Pfeiler Catherine M Phelan Mila Pinchev Dijana Plaseska-Karanfilska Bruce Poppe Mary E Porteous Ross Prentice Nadege Presneau Darya Prokofieva Elizabeth Pugh Miquel Angel Pujana Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Hedy S Rennert Valerie Rhenius Kerstin Rhiem Andrea Richardson Gustavo C Rodriguez Atocha Romero Jane Romm Matti A Rookus Anja Rudolph Thomas Ruediger Emmanouil Saloustros Joyce Sanders Dale P Sandler Suleeporn Sangrajrang Elinor J Sawyer Daniel F Schmidt Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Sheila Seal Leigha Senter Caroline Seynaeve Mitul Shah Priyanka Sharma Chen-Yang Shen Xin Sheng Hermela Shimelis Martha J Shrubsole Xiao-Ou Shu Lucy E Side Christian F Singer Christof Sohn Melissa C Southey John J Spinelli Amanda B Spurdle Christa Stegmaier Dominique Stoppa-Lyonnet Grzegorz Sukiennicki Harald Surowy Christian Sutter Anthony Swerdlow Csilla I Szabo Rulla M Tamimi Yen Y Tan Jack A Taylor Maria-Isabel Tejada Maria Tengström Soo H Teo Mary B Terry Daniel C Tessier Alex Teulé Kathrin Thöne Darcy L Thull Maria Grazia Tibiletti Laima Tihomirova Marc Tischkowitz Amanda E Toland Rob A E M Tollenaar Ian Tomlinson Ling Tong Diana Torres Martine Tranchant Thérèse Truong Kathy Tucker Nadine Tung Jonathan Tyrer Hans-Ulrich Ulmer Celine Vachon Christi J van Asperen David Van Den Berg Ans M W van den Ouweland Elizabeth J van Rensburg Liliana Varesco Raymonda Varon-Mateeva Ana Vega Alessandra Viel Joseph Vijai Daniel Vincent Jason Vollenweider Lisa Walker Zhaoming Wang Shan Wang-Gohrke Barbara Wappenschmidt Clarice R Weinberg Jeffrey N Weitzel Camilla Wendt Jelle Wesseling Alice S Whittemore Juul T Wijnen Walter Willett Robert Winqvist Alicja Wolk Anna H Wu Lucy Xia Xiaohong R Yang Drakoulis Yannoukakos Daniela Zaffaroni Wei Zheng Bin Zhu Argyrios Ziogas Elad Ziv Kristin K Zorn Manuela Gago-Dominguez Arto Mannermaa Håkan Olsson Manuel R Teixeira Jennifer Stone Kenneth Offit Laura Ottini Sue K Park Mads Thomassen Per Hall Alfons Meindl Rita K Schmutzler Arnaud Droit Gary D Bader Paul D P Pharoah Fergus J Couch Douglas F Easton Peter Kraft Georgia Chenevix-Trench Montserrat García-Closas Marjanka K Schmidt Antonis C Antoniou Jacques Simard

Nat Genet 2017 Dec 23;49(12):1767-1778. Epub 2017 Oct 23.

Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808456PMC
December 2017

Primum non nocere: Are we ready for POLE testing in endometrial cancer?

Gynecol Oncol 2017 11 22;147(2):240-242. Epub 2017 Sep 22.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, The Ohio State University Wexner Medical Center, Columbus, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2017.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705034PMC
November 2017

Traditional Approaches to Molecular Genetic Analysis.

Adv Exp Med Biol 2017 ;943:99-118

Department of Obstetrics and Gynecology, Ohio State University Comprehensive Cancer Center, Columbus, OH, 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-43139-0_4DOI Listing
September 2017

Identification of endometrial cancer methylation features using combined methylation analysis methods.

PLoS One 2017 9;12(3):e0173242. Epub 2017 Mar 9.

Department of Obstetrics and Gynecology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173242PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344376PMC
September 2017

Novel frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations.

Oncotarget 2017 Sep 12;8(40):68758-68768. Epub 2017 Aug 12.

James Comprehensive Cancer Center and the Department of Obstetrics and Gynecology, The Ohio State University, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.20213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620294PMC
September 2017

FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study.

Gynecol Oncol 2017 05 15;145(2):366-373. Epub 2017 Mar 15.

Queensland University of Technology (QUT) at the Translational Research Institute, Brisbane, Australia; Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2017.02.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433848PMC
May 2017

Clinicopathologic Significance of Mismatch Repair Defects in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study.

J Clin Oncol 2016 09 20;34(25):3062-8. Epub 2016 Jun 20.

D. Scott McMeekin and Lisa M. Landrum, University of Oklahoma Health Sciences Center, Oklahoma City, OK; David L. Tritchler, Heather A. Lankes, and Shamshad Ali, NRG Oncology Statistics and Data Management Center; Shashikant B. Lele, Roswell Park Cancer Institute, Buffalo; Michael L. Pearl, Stony Brook University Hospital, Stony Brook, NY; David E. Cohn, Floor J. Backes, and Paul J. Goodfellow, The Ohio State University; Nilsa Ramirez, Research Institute at Nationwide Children's Hospital, Columbus, OH; David G. Mutch, Matthew A. Powell, and Feng Gao, Washington University School of Medicine, St. Louis, MO; Melissa A. Geller, University of Minnesota, Minneapolis, MN; Richard Zaino, Penn State Milton S. Hersey Medical Center, Hershey, PA; Russell D. Broaddus, The University of Texas MD Anderson Cancer Center, Houston, TX; Kathleen M. Darcy, Women's Health Integrated Research Collective, Annandale, VA; and Paul A. DiSilvestro, Women and Infants Hospital of Rhode Island, Providence, RI.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.67.8722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012715PMC
September 2016

Prognostic Significance of POLE Exonuclease Domain Mutations in High-Grade Endometrioid Endometrial Cancer on Survival and Recurrence: A Subanalysis.

Int J Gynecol Cancer 2016 06;26(5):933-8

*Division of Gynecology Oncology, Department of Obstetrics and Gynecology, The Ohio State University, College of Medicine, Columbus, OH; †Division of Gynecology Oncology, Department of Obstetrics and Gynecology, Washington University, St Louis, MO; and ‡Center for Biostatistics, Department of Biomedical Informatics, The Ohio State University, Columbus, OH.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IGC.0000000000000681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874836PMC
June 2016

Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence.

Nucleic Acids Res 2016 05 6;44(9):4105-22. Epub 2016 Jan 6.

Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210, USA Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH 43210, USA The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkv1528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872073PMC
May 2016

Estrogen receptor-alpha as a predictive biomarker in endometrioid endometrial cancer.

Gynecol Oncol 2016 05 10;141(2):312-317. Epub 2016 Mar 10.

Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2016.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878441PMC
May 2016

Integrated analysis of germline and somatic variants in ovarian cancer.

Nat Commun 2014 ;5:3156

1] The Genome Institute, Washington University, St. Louis, Missouri 63108, USA [2] Department of Genetics, Washington University, St. Louis, Missouri 63108, USA [3] Siteman Cancer Center, Washington University, St. Louis, Missouri 63108, USA [4] Department of Medicine, Washington University, St. Louis, Missouri 63108, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025965PMC
March 2016

Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study.

J Clin Oncol 2015 Dec 9;33(36):4301-8. Epub 2015 Nov 9.

Paul J. Goodfellow, Caroline C. Billingsley, David E. Cohn, Heather Hampel, Alexis S. Chassen, Luke V. Simmons, and Floor Backes, Ohio State University; Nilsa Ramirez, Research Institute at Nationwide Children's Hospital, Columbus, OH; Heather A. Lankes and Shamshad Ali, NRG Oncology Statistics and Data Management Center; Shashikant B. Lele, Roswell Park Cancer Institute, Buffalo; Michael L. Pearl, Stony Brook University Hospital, Stony Brook, NY; Russell J. Broaddus, University of Texas MD Anderson Cancer Center, Houston, TX; Colin C. Pritchard, University of Washington, Seattle, WA; Amy P. Schmidt, Feng Gao, Matthew A. Powell, and David Mutch, Washington University School of Medicine, St Louis, MO; Louise A. Brinton, National Cancer Institute, Washington, DC; Lisa M. Landrum, University of Oklahoma Health Sciences Center, Oklahoma City, OK; Melissa A. Geller, University of Minnesota, Minneapolis, MN; Paul A. DiSilvestro, Women and Infants Hospital of Rhode Island, Providence, RI; and Richard J. Zaino, Penn State Milton S. Hershey Medical Center, Hershey, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2015.63.9518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678181PMC
December 2015

Patterns of CTCF and ZFHX3 Mutation and Associated Outcomes in Endometrial Cancer.

J Natl Cancer Inst 2015 Nov 1;107(11). Epub 2015 Sep 1.

Department of Obstetrics and Gynecology, Division of Gynecology Oncology (CJW, MAM, MJO, DEC, PJG), Department of Biomedical Informatics, Center for Biostatistics, College of Medicine (JPM, KRC), The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute (CJW, MAM, MJO, JPM, KRC, DEC, PJG), Department of Physics, Department of Chemistry & Biochemistry, Department of Internal Medicine, Division of Hematology, Center for RNA Biology (RB), The Ohio State University, Columbus, OH; Department of Obstetrics and Gynecology, Division of Gynecology Oncology, Washington University, St. Louis, MO (DGM).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643635PMC
November 2015

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.

Genes Dev 2015 Aug;29(16):1707-20

Solid Tumor Biology Program, James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA; Department of Molecular Genetics, College of Arts and Sciences, The Ohio State University, Columbus, Ohio 43210, USA; Department of Molecular Virology, Immunology, and Medical Genetics, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.262568.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561480PMC
August 2015

Novel APC promoter and exon 1B deletion and allelic silencing in three mutation-negative classic familial adenomatous polyposis families.

Genome Med 2015 4;7(1):42. Epub 2015 May 4.

Division of Gastroenterology, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8124, St. Louis, Missouri MO 63110 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13073-015-0148-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418073PMC
May 2015

Polymerase ɛ (POLE) mutations in endometrial cancer: clinical outcomes and implications for Lynch syndrome testing.

Cancer 2015 Feb 15;121(3):386-94. Epub 2014 Sep 15.

Department of Obstetrics and Gynecology, Division of Gynecology Oncology, The Ohio State University, College of Medicine, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.29046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304930PMC
February 2015

Aberrantly activated pSTAT3-Ser727 in human endometrial cancer is suppressed by HO-3867, a novel STAT3 inhibitor.

Gynecol Oncol 2014 Oct 16;135(1):133-41. Epub 2014 Jul 16.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Comprehensive Cancer Center and Solid Tumor Biology Program, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2014.07.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283766PMC
October 2014

Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers.

BMC Genomics 2014 Oct 6;15:868. Epub 2014 Oct 6.

Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St, Louis MO 63108, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-15-868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198682PMC
October 2014

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.

Authors:
Kristen S Purrington Susan Slager Diana Eccles Drakoulis Yannoukakos Peter A Fasching Penelope Miron Jane Carpenter Jenny Chang-Claude Nicholas G Martin Grant W Montgomery Vessela Kristensen Hoda Anton-Culver Paul Goodfellow William J Tapper Sajjad Rafiq Susan M Gerty Lorraine Durcan Irene Konstantopoulou Florentia Fostira Athanassios Vratimos Paraskevi Apostolou Irene Konstanta Vassiliki Kotoula Sotiris Lakis Meletios A Dimopoulos Dimosthenis Skarlos Dimitrios Pectasides George Fountzilas Matthias W Beckmann Alexander Hein Matthias Ruebner Arif B Ekici Arndt Hartmann Ruediger Schulz-Wendtland Stefan P Renner Wolfgang Janni Brigitte Rack Christoph Scholz Julia Neugebauer Ulrich Andergassen Michael P Lux Lothar Haeberle Christine Clarke Nirmala Pathmanathan Anja Rudolph Dieter Flesch-Janys Stefan Nickels Janet E Olson James N Ingle Curtis Olswold Seth Slettedahl Jeanette E Eckel-Passow S Keith Anderson Daniel W Visscher Victoria L Cafourek Hugues Sicotte Naresh Prodduturi Elisabete Weiderpass Leslie Bernstein Argyrios Ziogas Jennifer Ivanovich Graham G Giles Laura Baglietto Melissa Southey Veli-Matti Kosma Hans-Peter Fischer Malcom W R Reed Simon S Cross Sandra Deming-Halverson Martha Shrubsole Qiuyin Cai Xiao-Ou Shu Mary Daly Joellen Weaver Eric Ross Jennifer Klemp Priyanka Sharma Diana Torres Thomas Rüdiger Heidrun Wölfing Hans-Ulrich Ulmer Asta Försti Thaer Khoury Shicha Kumar Robert Pilarski Charles L Shapiro Dario Greco Päivi Heikkilä Kristiina Aittomäki Carl Blomqvist Astrid Irwanto Jianjun Liu Vernon Shane Pankratz Xianshu Wang Gianluca Severi Arto Mannermaa Douglas Easton Per Hall Hiltrud Brauch Angela Cox Wei Zheng Andrew K Godwin Ute Hamann Christine Ambrosone Amanda Ewart Toland Heli Nevanlinna Celine M Vachon Fergus J Couch

Carcinogenesis 2014 May 9;35(5):1012-9. Epub 2013 Dec 9.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgt404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004200PMC
May 2014

Hypermethylation of miR-203 in endometrial carcinomas.

Gynecol Oncol 2014 May 14;133(2):340-5. Epub 2014 Feb 14.

Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2014.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015135PMC
May 2014

Mismatch repair protein expression in 1049 endometrial carcinomas, associations with body mass index, and other clinicopathologic variables.

Gynecol Oncol 2014 Apr 17;133(1):43-7. Epub 2014 Jan 17.

Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2014.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127575PMC
April 2014

Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.

Mod Pathol 2014 Jan 14;27(1):128-34. Epub 2013 Jun 14.

1] Department of Pathology and Laboratory Medicine, University of British Columbia, BC Cancer Agency, Centre for Translational and Applied Genomics, Vancouver, BC, Canada [2] Department of Molecular Oncology, BC Cancer Agency, Vancouver, BC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2013.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915240PMC
January 2014

CMS: a web-based system for visualization and analysis of genome-wide methylation data of human cancers.

PLoS One 2013 22;8(4):e60980. Epub 2013 Apr 22.

Department of Molecular Medicine/Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060980PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632540PMC
November 2013

Promoter hypomethylation of EpCAM-regulated bone morphogenetic protein gene family in recurrent endometrial cancer.

Clin Cancer Res 2013 Nov 27;19(22):6272-85. Epub 2013 Sep 27.

Authors' Affiliations: Department of Molecular Medicine, Institute of Biotechnology; Department of Urology; Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio; Department of Computer Science, University of Texas at San Antonio, San Antonio, Texas; Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin; Department of Obstetrics and Gynecology, Tri-Service General Hospital; Laboratory of Epigenetics, Cancer Stem Cells; Department and Graduate Institute of Biochemistry, National Defense Medical Center, Taiwan, Republic of China; Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri; Department of Obstetrics and Gynecology, Ohio State University, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-1734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080631PMC
November 2013

Gynecologic Cancer InterGroup (GCIG) Endometrial Cancer Clinical Trials Planning Meeting: taking endometrial cancer trials into the translational era.

Int J Gynecol Cancer 2013 Oct;23(8):1528-34

*Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands; †Institute of Cancer Sciences, University of Manchester, United Kingdom; ‡Division of Hematology and Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA; §Division of Gynaecology, European Institute of Oncology, Milan, Italy; ∥Department of Gynecologic Oncology and Reproductive Medicine, MD Anderson Cancer Center, Houston, TX; ¶Department of Clinical Oncology, Barts Health NHS Trust, London, United Kingdom; #Department of Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY; **Department of Gynaecology, Newcastle University and Northern Institute for Cancer Research, Newcastle upon Tyne, United Kingdom; ††Department of Obstetrics and Gynecology, College of Medicine, Ohio State University, Columbus, OH; ‡‡Department of Gynaecologic Oncology, Royal Women's Hospital, and Melbourne University Dept of Obstetrics and Gynaecology, Australia; §§Department of Obstetrics and Gynecology, Haukeland University Hospital; and Department of Clinical Medicine, University of Bergen, Norway; and ∥∥Department of Radiation Oncology, Sunnybrook Cancer Center, Toronto, Canada.

View Article

Download full-text PDF

Source
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/IGC.0b013e3182a26edbDOI Listing
October 2013

Glycogen synthase kinase 3β inhibition as a therapeutic approach in the treatment of endometrial cancer.

Int J Mol Sci 2013 Aug 12;14(8):16617-37. Epub 2013 Aug 12.

Division of Dermatology, Department of Medicine, Washington University School of Medicine, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms140816617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759928PMC
August 2013

Frequent mutations in the RPL22 gene and its clinical and functional implications.

Gynecol Oncol 2013 Mar 2;128(3):470-4. Epub 2012 Nov 2.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St. Louis, MO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2012.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845021PMC
March 2013

Lithium chloride and inhibition of glycogen synthase kinase 3β as a potential therapy for serous ovarian cancer.

Int J Gynecol Cancer 2013 Feb;23(2):361-6

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IGC.0b013e31827cfecbDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972899PMC
February 2013

BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma.

Cancer 2013 Jan 18;119(2):332-8. Epub 2012 Jul 18.

Division of Gynecologic Oncology, University of Washington Medical Center, Seattle, Washington 98195-6460, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.27720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966566PMC
January 2013

Reduced DICER1 elicits an interferon response in endometrial cancer cells.

Mol Cancer Res 2012 Mar 17;10(3):316-25. Epub 2012 Jan 17.

Department of Surgery, Division of Gynecologic Oncology, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-11-0520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307918PMC
March 2012

Phosphatase and tensin homolog (PTEN) pseudogene expression in endometrial cancer: a conserved regulatory mechanism important in tumorigenesis?

Gynecol Oncol 2012 Feb 15;124(2):340-6. Epub 2011 Oct 15.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St. Louis, MO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2011.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954782PMC
February 2012

Lymphovascular space invasion is an independent risk factor for nodal disease and poor outcomes in endometrioid endometrial cancer.

Gynecol Oncol 2012 Jan 26;124(1):31-5. Epub 2011 Oct 26.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, Saint Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2011.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936402PMC
January 2012

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.

Authors:
Christopher A Haiman Gary K Chen Celine M Vachon Federico Canzian Alison Dunning Robert C Millikan Xianshu Wang Foluso Ademuyiwa Shahana Ahmed Christine B Ambrosone Laura Baglietto Rosemary Balleine Elisa V Bandera Matthias W Beckmann Christine D Berg Leslie Bernstein Carl Blomqvist William J Blot Hiltrud Brauch Julie E Buring Lisa A Carey Jane E Carpenter Jenny Chang-Claude Stephen J Chanock Daniel I Chasman Christine L Clarke Angela Cox Simon S Cross Sandra L Deming Robert B Diasio Athanasios M Dimopoulos W Ryan Driver Thomas Dünnebier Lorraine Durcan Diana Eccles Christopher K Edlund Arif B Ekici Peter A Fasching Heather S Feigelson Dieter Flesch-Janys Florentia Fostira Asta Försti George Fountzilas Susan M Gerty Graham G Giles Andrew K Godwin Paul Goodfellow Nikki Graham Dario Greco Ute Hamann Susan E Hankinson Arndt Hartmann Rebecca Hein Judith Heinz Andrea Holbrook Robert N Hoover Jennifer J Hu David J Hunter Sue A Ingles Astrid Irwanto Jennifer Ivanovich Esther M John Nicola Johnson Arja Jukkola-Vuorinen Rudolf Kaaks Yon-Dschun Ko Laurence N Kolonel Irene Konstantopoulou Veli-Matti Kosma Swati Kulkarni Diether Lambrechts Adam M Lee Loïc Le Marchand Timothy Lesnick Jianjun Liu Sara Lindstrom Arto Mannermaa Sara Margolin Nicholas G Martin Penelope Miron Grant W Montgomery Heli Nevanlinna Stephan Nickels Sarah Nyante Curtis Olswold Julie Palmer Harsh Pathak Dimitrios Pectasides Charles M Perou Julian Peto Paul D P Pharoah Loreall C Pooler Michael F Press Katri Pylkäs Timothy R Rebbeck Jorge L Rodriguez-Gil Lynn Rosenberg Eric Ross Thomas Rüdiger Isabel dos Santos Silva Elinor Sawyer Marjanka K Schmidt Rüdiger Schulz-Wendtland Fredrick Schumacher Gianluca Severi Xin Sheng Lisa B Signorello Hans-Peter Sinn Kristen N Stevens Melissa C Southey William J Tapper Ian Tomlinson Frans B L Hogervorst Els Wauters JoEllen Weaver Hans Wildiers Robert Winqvist David Van Den Berg Peggy Wan Lucy Y Xia Drakoulis Yannoukakos Wei Zheng Regina G Ziegler Afshan Siddiq Susan L Slager Daniel O Stram Douglas Easton Peter Kraft Brian E Henderson Fergus J Couch

Nat Genet 2011 Oct 30;43(12):1210-4. Epub 2011 Oct 30.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279120PMC
October 2011

Aberrant methylation of the X-linked ribosomal S6 kinase RPS6KA6 (RSK4) in endometrial cancers.

Clin Cancer Res 2011 Apr 3;17(8):2120-9. Epub 2011 Mar 3.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St Louis, Missouri 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-10-2668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242504PMC
April 2011

DICER1 expression and outcomes in endometrioid endometrial adenocarcinoma.

Cancer 2011 Apr 8;117(7):1446-53. Epub 2010 Nov 8.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.25665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065965PMC
April 2011

Infrequent methylation of the DUSP6 phosphatase in endometrial cancer.

Gynecol Oncol 2010 Oct 16;119(1):146-50. Epub 2010 Jul 16.

Division of Endocrine and Oncologic Surgery, Department of Surgery, Washington University School of Medicine and Siteman Cancer Center, 660 South Euclid Avenue, Box 8067, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2010.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939303PMC
October 2010

Promoter hypermethylation of CIDEA, HAAO and RXFP3 associated with microsatellite instability in endometrial carcinomas.

Gynecol Oncol 2010 May 7;117(2):239-47. Epub 2010 Mar 7.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2010.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849881PMC
May 2010

FGFR2 mutations are rare across histologic subtypes of ovarian cancer.

Gynecol Oncol 2010 Apr 27;117(1):125-9. Epub 2010 Jan 27.

Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2009.12.002DOI Listing
April 2010

The MLH1 -93 promoter variant influences gene expression.

Cancer Epidemiol 2010 Feb 8;34(1):93-5. Epub 2010 Jan 8.

Department of Feed Science, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnical University, Wuhan, Hubei, China.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18777821090018
Publisher Site
http://dx.doi.org/10.1016/j.canep.2009.12.009DOI Listing
February 2010

Epitope-positive truncating MLH1 mutation and loss of PMS2: implications for IHC-directed genetic testing for Lynch syndrome.

Fam Cancer 2009 12;8(4):501-4. Epub 2009 Aug 12.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10689-009-9276-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771133PMC
January 2010

Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 oncogene in endometrial cancer.

Cancer Res 2009 Dec 3;69(23):9038-46. Epub 2009 Nov 3.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-1499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789184PMC
December 2009

Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing.

Nucleic Acids Res 2009 Aug 3;37(14):4603-12. Epub 2009 Jun 3.

Department of Genetics, Center for Genome Sciences, Washington University School of Medicine, St Louis, Missouri, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
Publisher Site
http://dx.doi.org/10.1093/nar/gkp457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724279PMC
August 2009

ATR mutation in endometrioid endometrial cancer is associated with poor clinical outcomes.

J Clin Oncol 2009 Jul 26;27(19):3091-6. Epub 2009 May 26.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes Jewish Plaza, Box 8064, St Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2008.19.9802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716934PMC
July 2009

Absence of MGMT promoter methylation in endometrial cancer.

Gynecol Oncol 2009 Jan 29;112(1):224-8. Epub 2008 Oct 29.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S009082580800713
Publisher Site
http://dx.doi.org/10.1016/j.ygyno.2008.08.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949277PMC
January 2009

Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair.

Gynecol Oncol 2008 Feb 26;108(2):438-44. Epub 2007 Nov 26.

Divison of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes-Jewish Hospital Plaza, 3rd Floor Maternity, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2007.09.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023170PMC
February 2008

Excess of early onset multiple myeloma in endometrial cancer probands and their relatives suggests common susceptibility.

Gynecol Oncol 2007 May 1;105(2):390-4. Epub 2007 Mar 1.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, 4911 Barnes Jewish Plaza, Box 8064, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2006.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577217PMC
May 2007

Differential methylation hybridization array of endometrial cancers reveals two novel cancer-specific methylation markers.

Clin Cancer Res 2007 May;13(10):2882-9

Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St. Louis, Missouri 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-06-2367DOI Listing
May 2007

Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type.

J Clin Oncol 2007 May;25(15):2042-8

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2006.08.2107
Publisher Site
http://dx.doi.org/10.1200/JCO.2006.08.2107DOI Listing
May 2007

Evidence for heritable predisposition to epigenetic silencing of MLH1.

Int J Cancer 2007 Apr;120(8):1684-8

Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.22406
Publisher Site
http://dx.doi.org/10.1002/ijc.22406DOI Listing
April 2007

Body mass index: relationship to clinical, pathologic and features of microsatellite instability in endometrial cancer.

Gynecol Oncol 2007 Mar 14;104(3):535-9. Epub 2006 Nov 14.

Department of Obstetrics and Gynecology, Washington University School of Medicine, Saint Louis, MO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2006.09.019DOI Listing
March 2007

Transcriptional profiling endometrial carcinomas microdissected from DES-treated mice identifies changes in gene expression associated with estrogenic tumor promotion.

Int J Cancer 2006 Oct;119(8):1843-9

Division of Biology and Biomedical Sciences, Washington University School of Medicine, S. Euclid, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.22063DOI Listing
October 2006

DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesis.

Mod Pathol 2006 Oct 30;19(10):1333-8. Epub 2006 Jun 30.

Division of Gynecologic Oncology, Washington University School of Medicine and Siteman Cancer Center, St Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.3800654DOI Listing
October 2006

DNA repair pathway profiling and microsatellite instability in colorectal cancer.

Clin Cancer Res 2006 Sep;12(17):5104-11

Department of Medicine, Washington University School of Medicine and Siteman Cancer Center, Saint Louis, Missouri 63110-1093, USA.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/content/12/17/5104.ful
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-06-0547DOI Listing
September 2006

MLH3 mutation in endometrial cancer.

Cancer Res 2006 Aug;66(15):7502-8

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Washington University School of Medicine, 4911 Barnes-Jewish Hospital Plaza, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-06-0248DOI Listing
August 2006

Defective DNA mismatch repair and XRCC2 mutation in uterine carcinosarcomas.

Gynecol Oncol 2006 Jan 16;100(1):107-10. Epub 2005 Sep 16.

Department of OB/GYN, Division of Gynecologic Oncology, Washington University School of Medicine, 4911 Barnes-Jewish Hospital Plaza, Maternity Building, 3rd Floor, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2005.07.130DOI Listing
January 2006

Concordance of pharmacogenetic markers in germline and colorectal tumor DNA.

Pharmacogenomics 2005 Dec;6(8):873-7

Washington University School of Medicine, Campus Box 8069-660 South Euclid AvenueSt Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/14622416.6.8.873DOI Listing
December 2005

A Drosophila model of multiple endocrine neoplasia type 2.

Genetics 2005 Nov 18;171(3):1057-81. Epub 2005 Jun 18.

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.104.038018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456812PMC
November 2005

Diethylstilbestrol effects and lymphomagenesis in Mlh1-deficient mice.

Int J Cancer 2005 Jul;115(4):666-9

Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.20918
Publisher Site
http://dx.doi.org/10.1002/ijc.20918DOI Listing
July 2005

IGSF4 promoter methylation and expression silencing in human cervical cancer.

Gynecol Oncol 2005 Jan;96(1):150-8

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2004.08.050DOI Listing
January 2005

RAS/RAF mutation and defective DNA mismatch repair in endometrial cancers.

Am J Obstet Gynecol 2004 Apr;190(4):935-42

Division of Gynecologic Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2004.01.017DOI Listing
April 2004