Paul Foster

Paul Foster

UNVERIFIED PROFILE

Are you Paul Foster?   Register this Author

Register author
Paul Foster

Paul Foster

Publications by authors named "Paul Foster"

Are you Paul Foster?   Register this Author

100Publications

2249Reads

47Profile Views

Targeting MicroRNAs: Promising Future Therapeutics in the Treatment of Allergic Airway Disease.

Crit Rev Eukaryot Gene Expr 2018 ;28(2):125-127

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW 2305, Australia; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1615/CritRevEukaryotGeneExpr.2018022218DOI Listing
August 2019

Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors.

Eur J Med Chem 2019 Aug 12;182:111614. Epub 2019 Aug 12.

Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmech.2019.111614DOI Listing
August 2019

H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues.

Sci Rep 2019 Jul 31;9(1):11113. Epub 2019 Jul 31.

Department of Pharmacognosy, Faculty of Life Sciences, University of Vienna, Althanstraße 14, 1090, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-47434-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668471PMC
July 2019

Associations with Corneal Hysteresis in a Population Cohort: Results from 96 010 UK Biobank Participants.

Ophthalmology 2019 Jul 5. Epub 2019 Jul 5.

National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom; UCL Institute of Ophthalmology, London, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2019.06.029DOI Listing
July 2019

MicroRNAs in Lung Diseases.

Chest 2019 Jun 27. Epub 2019 Jun 27.

Priority Research Centre for Healthy Lungs, Department of Microbiology and Immunology, School of Biomedical Sciences and Medicine, Faculty of Health and Medicine, Hunter Medical Research Institute and The University of Newcastle, Newcastle, NSW, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chest.2019.06.008DOI Listing
June 2019

A Conflicted Tale of Two Novel AR Antagonists In Vitro and In Vivo: Pyrifluquinazon Versus Bisphenol C.

Toxicol Sci 2019 Apr;168(2):632-643

Reproductive Toxicology Branch, Toxicology Assessment Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency (U.S. EPA), Research Triangle Park, North Carolina 27711.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfz010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551625PMC
April 2019

Laser peripheral iridotomy for the prevention of angle closure: a single-centre, randomised controlled trial.

Lancet 2019 Apr 14;393(10181):1609-1618. Epub 2019 Mar 14.

Dana Center for Preventive Ophthalmology, Wilmer Eye Institute and Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(18)32607-2DOI Listing
April 2019

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury.

Front Immunol 2019 16;10:826. Epub 2019 Apr 16.

Priority Research Centre's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.00826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477147PMC
April 2019

Ten-year incidence of primary angle closure in elderly Chinese: the Liwan Eye Study.

Br J Ophthalmol 2019 Mar 18;103(3):355-360. Epub 2018 May 18.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bjophthalmol-2017-311808DOI Listing
March 2019

Evidence for Local and Systemic Immune Activation in Functional Dyspepsia and the Irritable Bowel Syndrome: A Systematic Review.

Am J Gastroenterol 2019 Mar;114(3):429-436

School of Biomedical Sciences & Pharmacy, Faculty of Health & Medicine, University of Newcastle, Newcastle, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41395-018-0377-0DOI Listing
March 2019

Finding the bad actor: Challenges in identifying toxic constituents in botanical dietary supplements.

Food Chem Toxicol 2019 Feb 21;124:431-438. Epub 2018 Dec 21.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fct.2018.12.026DOI Listing
February 2019

In utero exposure to simvastatin reduces postnatal survival and permanently alters reproductive tract development in the Crl:CD(SD) male rat.

Toxicol Appl Pharmacol 2019 02 11;365:112-123. Epub 2019 Jan 11.

Reproductive Toxicology Branch, Toxicity Assessment Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, B105-04, 109 TW Alexander Dr., Research Triangle Park, NC 27709, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2019.01.001DOI Listing
February 2019

Cohort profile: design and methods in the eye and vision consortium of UK Biobank.

BMJ Open 2019 Feb 21;9(2):e025077. Epub 2019 Feb 21.

NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2018-025077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398663PMC
February 2019

Darkroom prone provocative testing in primary angle closure suspects and those with open angles.

Br J Ophthalmol 2019 Feb 28. Epub 2019 Feb 28.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

View Article

Download full-text PDF

Source
http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3133
Publisher Site
http://dx.doi.org/10.1136/bjophthalmol-2018-313362DOI Listing
February 2019

Retinal Vasculometry Associations with Cardiometabolic Risk Factors in the European Prospective Investigation of Cancer-Norfolk Study.

Ophthalmology 2019 Jan 1;126(1):96-106. Epub 2018 Aug 1.

Integrative Epidemiology Research Group, UCL Institute of Ophthalmology, London, United Kingdom; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2018.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302796PMC
January 2019

Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease.

J Leukoc Biol 2019 Jan 27;105(1):143-150. Epub 2018 Sep 27.

Priority Research Centres for Healthy Lungs and GrowUpWell, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/JLB.3AB0518-178RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487813PMC
January 2019

Ascorbic acid metabolites are involved in intraocular pressure control in the general population.

Redox Biol 2019 01 13;20:349-353. Epub 2018 Oct 13.

Section of Academic Ophthalmology, Faculty of Life Sciences and Medicine, Kings' College London, UK; King's College London Department of Twin Research and Genetic Epidemiology, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.redox.2018.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223183PMC
January 2019

Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.

Nat Commun 2019 01 8;10(1):155. Epub 2019 Jan 8.

Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4029, Australia.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41467-018-07819-1
Publisher Site
http://dx.doi.org/10.1038/s41467-018-07819-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325104PMC
January 2019

Response to the letter to the editor for embryo-fetal development studies with the dietary supplement vinpocetine in the rat and rabbit.

Birth Defects Res 2018 11 25;110(18):1374-1375. Epub 2018 Oct 25.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdr2.1401DOI Listing
November 2018

Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography.

JAMA Neurol 2018 Oct;75(10):1198-1205

National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust NHS Foundation Trust and UCL Institute of Ophthalmology, London, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaneurol.2018.1578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233846PMC
October 2018

Treating the Eyes to Help the Brain: The Association Between Visual and Cognitive Function.

JAMA Ophthalmol 2018 Sep;136(9):996-997

Department of Neuro-ophthalmology, Moorfields Eye Hospital, London, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2018.2491DOI Listing
September 2018

SULFATION PATHWAYS: Insights into steroid sulfation and desulfation pathways.

J Mol Endocrinol 2018 08 15;61(2):T271-T283. Epub 2018 May 15.

Institute of Metabolism and Systems Research (IMSR)University of Birmingham, Birmingham, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/JME-18-0086DOI Listing
August 2018

Steroid sulfation research has come a long way.

J Mol Endocrinol 2018 08;61(2):E5-E6

Institute of Metabolism and Systems ResearchUniversity of Birmingham, Birmingham, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/JME-18-0109DOI Listing
August 2018

IL-6 Drives Neutrophil-Mediated Pulmonary Inflammation Associated with Bacteremia in Murine Models of Colitis.

Am J Pathol 2018 07 22;188(7):1625-1639. Epub 2018 Apr 22.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales; Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia; Priority Research Centre for Digestive Health and Neurogastroenterology, University of Newcastle, Callaghan, New South Wales. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2018.03.016DOI Listing
July 2018

Potential Role of MicroRNAs in the Regulation of Antiviral Responses to Influenza Infection.

Front Immunol 2018 4;9:1541. Epub 2018 Jul 4.

Priority Research Centre for Healthy Lungs, The University of Newcastle, Callaghan, NSW, Australia.

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fimmu.2018.01541
Publisher Site
http://dx.doi.org/10.3389/fimmu.2018.01541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039551PMC
July 2018

Embryo-fetal development studies with the dietary supplement vinpocetine in the rat and rabbit.

Birth Defects Res 2018 06 19;110(10):883-896. Epub 2018 Feb 19.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdr2.1207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980693PMC
June 2018

Uterine Paramesonephric Cysts in Sprague-Dawley Rats from National Toxicology Program Studies.

Toxicol Pathol 2018 06 29;46(4):421-430. Epub 2018 Apr 29.

1 Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623318772487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999558PMC
June 2018

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.

Authors:
Milly S Tedja Robert Wojciechowski Pirro G Hysi Nicholas Eriksson Nicholas A Furlotte Virginie J M Verhoeven Adriana I Iglesias Magda A Meester-Smoor Stuart W Tompson Qiao Fan Anthony P Khawaja Ching-Yu Cheng René Höhn Kenji Yamashiro Adam Wenocur Clare Grazal Toomas Haller Andres Metspalu Juho Wedenoja Jost B Jonas Ya Xing Wang Jing Xie Paul Mitchell Paul J Foster Barbara E K Klein Ronald Klein Andrew D Paterson S Mohsen Hosseini Rupal L Shah Cathy Williams Yik Ying Teo Yih Chung Tham Preeti Gupta Wanting Zhao Yuan Shi Woei-Yuh Saw E-Shyong Tai Xue Ling Sim Jennifer E Huffman Ozren Polašek Caroline Hayward Goran Bencic Igor Rudan James F Wilson Peter K Joshi Akitaka Tsujikawa Fumihiko Matsuda Kristina N Whisenhunt Tanja Zeller Peter J van der Spek Roxanna Haak Hanne Meijers-Heijboer Elisabeth M van Leeuwen Sudha K Iyengar Jonathan H Lass Albert Hofman Fernando Rivadeneira André G Uitterlinden Johannes R Vingerling Terho Lehtimäki Olli T Raitakari Ginevra Biino Maria Pina Concas Tae-Hwi Schwantes-An Robert P Igo Gabriel Cuellar-Partida Nicholas G Martin Jamie E Craig Puya Gharahkhani Katie M Williams Abhishek Nag Jugnoo S Rahi Phillippa M Cumberland Cécile Delcourt Céline Bellenguez Janina S Ried Arthur A Bergen Thomas Meitinger Christian Gieger Tien Yin Wong Alex W Hewitt David A Mackey Claire L Simpson Norbert Pfeiffer Olavi Pärssinen Paul N Baird Veronique Vitart Najaf Amin Cornelia M van Duijn Joan E Bailey-Wilson Terri L Young Seang-Mei Saw Dwight Stambolian Stuart MacGregor Jeremy A Guggenheim Joyce Y Tung Christopher J Hammond Caroline C W Klaver

Nat Genet 2018 06 28;50(6):834-848. Epub 2018 May 28.

Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41588-018-0127-7
Publisher Site
http://dx.doi.org/10.1038/s41588-018-0127-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980758PMC
June 2018

Kratom: a dangerous player in the opioid crisis.

J Community Hosp Intern Med Perspect 2018 12;8(3):107-110. Epub 2018 Jun 12.

Internal Medicine, Greater Baltimore Medical Center, Towson, MD, USA.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/20009666.2018.1
Publisher Site
http://dx.doi.org/10.1080/20009666.2018.1468693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998276PMC
June 2018

Analysing barriers to service improvement using a multi-level theory of innovation: the case of glaucoma outpatient clinics.

Sociol Health Illn 2018 05 13;40(4):654-669. Epub 2018 Feb 13.

Department of Applied Health Research, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1467-9566.12670DOI Listing
May 2018

Enhanced Pro-Inflammatory Response of Macrophages to Interleukin-33 in an Allergic Environment.

Int Arch Allergy Immunol 2018 5;176(1):74-82. Epub 2018 Apr 5.

Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000487573DOI Listing
May 2018

Developing standards for the development of glaucoma virtual clinics using a modified Delphi approach.

Br J Ophthalmol 2018 04 18;102(4):531-534. Epub 2017 Aug 18.

NIHR Biomedical Research Centre (BRC) at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bjophthalmol-2017-310504DOI Listing
April 2018

Toll-like receptor 2 and 4 have opposing roles in the pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease.

Am J Physiol Lung Cell Mol Physiol 2018 02 12;314(2):L298-L317. Epub 2017 Oct 12.

Priority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute and University of Newcastle, Callaghan, New South Wales , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00154.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866502PMC
February 2018

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure.

J Med Chem 2018 02 8;61(3):1031-1044. Epub 2018 Jan 8.

Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford , Mansfield Road, Oxford OX1 3QT, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jmedchem.7b01474DOI Listing
February 2018

Identification of IFN-γ and IL-27 as Critical Regulators of Respiratory Syncytial Virus-Induced Exacerbation of Allergic Airways Disease in a Mouse Model.

J Immunol 2018 01 22;200(1):237-247. Epub 2017 Nov 22.

Priority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, New South Wales 2308, Australia; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1601950DOI Listing
January 2018

Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice.

J Immunol 2018 01 6;200(2):632-642. Epub 2017 Dec 6.

Priority Research Centre for Healthy Lungs, Department of Microbiology and Immunology, School of Biomedical Sciences and Pharmacy, Faculty of Health and Hunter Medical Research Institute, The University of Newcastle, Callaghan, New South Wales 2305, Australia;

View Article

Download full-text PDF

Source
http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1700927
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1700927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760340PMC
January 2018

Residual Angle Closure One Year After Laser Peripheral Iridotomy in Primary Angle Closure Suspects.

Am J Ophthalmol 2017 Nov 6;183:111-117. Epub 2017 Sep 6.

Singapore Eye Research Institute and Singapore National Eye Center, Singapore; Duke-NUS Medical School, Singapore; National University Hospital, Singapore, and the Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2017.08.016DOI Listing
November 2017

Spreading activation in nonverbal memory networks.

Brain Inform 2017 Sep 28;4(3):187-199. Epub 2016 Nov 28.

San Francisco Clinical Neurosciences and University of California, San Francisco, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40708-016-0058-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563298PMC
September 2017

Vitamin E isoform γ-tocotrienol protects against emphysema in cigarette smoke-induced COPD.

Free Radic Biol Med 2017 09 3;110:332-344. Epub 2017 Jul 3.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore; Immunology Program, Life Science Institute, National University of Singapore, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2017.06.023DOI Listing
September 2017

A phase 2 randomised discontinuation trial of cabozantinib in patients with ovarian carcinoma.

Eur J Cancer 2017 09 26;83:229-236. Epub 2017 Jul 26.

Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2017.06.018DOI Listing
September 2017

The incidence of acute angle closure in Scotland: a prospective surveillance study.

Br J Ophthalmol 2017 Aug 9. Epub 2017 Aug 9.

Centre for Vision and Vascular Science, Queen's University, Belfast, Northern Ireland, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bjophthalmol-2017-310725DOI Listing
August 2017

TLR2, TLR4 AND MyD88 Mediate Allergic Airway Disease (AAD) and Streptococcus pneumoniae-Induced Suppression of AAD.

PLoS One 2016 16;11(6):e0156402. Epub 2016 Jun 16.

The Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156402PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911048PMC
July 2017

Virtual clinics in glaucoma care: face-to-face versus remote decision-making.

Br J Ophthalmol 2017 07 11;101(7):892-895. Epub 2016 Oct 11.

Glaucoma Service, Moorfields Eye Hospital London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bjophthalmol-2016-308993DOI Listing
July 2017

Mouse models of severe asthma: Understanding the mechanisms of steroid resistance, tissue remodelling and disease exacerbation.

Respirology 2017 07 11;22(5):874-885. Epub 2017 Apr 11.

Hunter Medical Research Institute, Priority Research Centre for Healthy Lungs, Newcastle, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.13052DOI Listing
July 2017

Modeling T 2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma.

Immunol Rev 2017 07;278(1):20-40

Paediatric Respiratory and Sleep Medicine Unit, Priority Research Centre for Healthy Lungs and GrowUpWell, University of Newcastle and Hunter Medical Research Institute, John Hunter Children's Hospital, Newcastle, NSW, Australia.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/imr.12549
Publisher Site
http://dx.doi.org/10.1111/imr.12549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492958PMC
July 2017

Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma.

Immunol Rev 2017 07;278(1):41-62

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, Newcastle, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imr.12543DOI Listing
July 2017

MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD.

JCI Insight 2017 04 6;2(7):e90443. Epub 2017 Apr 6.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/jci.insight.90443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374076PMC
April 2017

The Association of Systemic Medication and Disease With Intraocular Pressure.

JAMA Ophthalmol 2017 03;135(3):203-204

National Institute of Health Research Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, and University College London Institute of Ophthalmology, London, England4Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2016.5335DOI Listing
March 2017

Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity.

J Immunol 2017 03 18;198(5):2182-2190. Epub 2017 Jan 18.

Priority Research Centre for Healthy Lungs, Department of Microbiology and Immunology, School of Pharmacy and Biomedical Sciences, Faculty of Health and Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales 2308, Australia;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1601480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367520PMC
March 2017

Estrone Sulfate Transport and Steroid Sulfatase Activity in Colorectal Cancer: Implications for Hormone Replacement Therapy.

Front Pharmacol 2017 7;8:103. Epub 2017 Mar 7.

Institute of Metabolism and Systems Research, Centre for Endocrinology, Diabetes, and Metabolism, University of BirminghamBirmingham, UK; Centre for Endocrinology, Diabetes, and Metabolism, Birmingham Health PartnersBirmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2017.00103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339229PMC
March 2017

MicroRNAs as therapeutics for future drug delivery systems in treatment of lung diseases.

Drug Deliv Transl Res 2017 02;7(1):168-178

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW, 2305, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13346-016-0343-6DOI Listing
February 2017

Associations with Retinal Pigment Epithelium Thickness Measures in a Large Cohort: Results from the UK Biobank.

Ophthalmology 2017 01 6;124(1):105-117. Epub 2016 Oct 6.

NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, University College London, London, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ophtha.2016.07.033DOI Listing
January 2017

Influence of Study Design on Developmental and Reproductive Toxicology Study Outcomes.

Authors:
Paul M D Foster

Toxicol Pathol 2017 01 5;45(1):107-113. Epub 2016 Oct 5.

1 Toxicology Branch, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623316671608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225034PMC
January 2017

TRAIL signaling is proinflammatory and proviral in a murine model of rhinovirus 1B infection.

Am J Physiol Lung Cell Mol Physiol 2017 01 11;312(1):L89-L99. Epub 2016 Nov 11.

Experimental and Translational Respiratory Medicine Group, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00200.2016DOI Listing
January 2017

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

Hum Mol Genet 2017 01;26(2):438-453

Statistical Genetics, QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Brisbane, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddw399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968632PMC
January 2017

TRAIL deficiency and PP2A activation with salmeterol ameliorates egg allergen-driven eosinophilic esophagitis.

Am J Physiol Gastrointest Liver Physiol 2016 12 13;311(6):G998-G1008. Epub 2016 Oct 13.

The Priority Research Centre GrowUpWell, Newcastle, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpgi.00151.2016DOI Listing
December 2016

Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial.

Lancet 2016 Oct;388(10052):1389-1397

Health Services Research Unit, University of Aberdeen, Aberdeen, UK; Centre for Health Care Randomised Trials, University of Aberdeen, Aberdeen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(16)30956-4DOI Listing
October 2016

Defining excellence: next steps for practicing clinicians seeking to prevent diagnostic error.

J Community Hosp Intern Med Perspect 2016 7;6(4):31994. Epub 2016 Sep 7.

Department of Philosophy, Villanova University, Villanova, PA, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016746PMC
http://dx.doi.org/10.3402/jchimp.v6.31994DOI Listing
September 2016

Endocarditis due to Gemella haemolysans in a newly diagnosed multiple myeloma patient.

J Community Hosp Intern Med Perspect 2016 7;6(4):32357. Epub 2016 Sep 7.

Department of Medicine, Greater Baltimore Medical Center, Towson, MD, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016745PMC
http://dx.doi.org/10.3402/jchimp.v6.32357DOI Listing
September 2016

Bromodomain and Extra Terminal (BET) Inhibitor Suppresses Macrophage-Driven Steroid-Resistant Exacerbations of Airway Hyper-Responsiveness and Inflammation.

PLoS One 2016;11(9):e0163392. Epub 2016 Sep 22.

Priority Research Centre for Healthy Lungs, School of Biomedical Sciences & Pharmacy, Faculty of Health and Medicine and Hunter Medical Research Institute, The University of Newcastle, Callaghan, NSW 2300, Australia.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033241PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163392PLOS
September 2016

The Accuracy and Reliability of Crowdsource Annotations of Digital Retinal Images.

Transl Vis Sci Technol 2016 Sep 21;5(5). Epub 2016 Sep 21.

NIHR Biomedical Research Centre at Moorfields Eye Hospital & UCL Institute of Ophthalmology, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/tvst.5.5.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032847PMC
September 2016

Trends in the use and cost of antipsychotics among older adults from 2007 to 2013: a repeated cross-sectional study.

CMAJ Open 2016 Apr-Jun;4(2):E292-7. Epub 2016 Jun 10.

Schulich School of Medicine and Dentistry (Foster), Western University, London; Institute for Clinical Evaluative Sciences (Camacho, Vigod, Yao, Juurlink, Paterson, Mamdani, Martins, Gomes), Toronto; Applied Health Research Centre (Foster, Mamdani, Gomes), St. Michael's Hospital, Toronto; Women's College Hospital and Research Institute (Vigod), Toronto; Departments of Medicine (Juurlink)and Psychiatry (Vigod) and Institute of Health Policy, Management and Evaluation (Vigod, Juurlink, Paterson, Mamdani, Gomes), University of Toronto, Toronto; Department of Family Medicine (Paterson), McMaster University, Hamilton, Ont. Paul Foster, David Juurlink, Michael Paterson, Muhammad Mamdani and Tara Gomes conceived the study. Ximena Camacho, Zhan Yao and Diana Martins acquired the data. Paul Foster and Tara Gomes drafted the manuscript, and Simone Vigod, David Juurlink, Michael Paterson, Muhammad Mamdani and Tara Gomes revised the manuscript for important intellectual content. All of the authors designed the study, contributed to data analysis and interpretation, gave approval of the final version to be published and agreed to act as guarantors of the work.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.9778/cmajo.20150095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933600PMC
July 2016

Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors.

Bioorg Med Chem 2016 06 22;24(12):2762-7. Epub 2016 Apr 22.

Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2016.04.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896991PMC
June 2016

In touch with your feminine side: how oestrogen metabolism impacts prostate cancer.

Endocr Relat Cancer 2016 06 18;23(6):R249-66. Epub 2016 May 18.

Institute of Metabolism and Systems ResearchUniversity of Birmingham, Birmingham, UK Centre for EndocrinologyDiabetes and Metabolism, Birmingham Healthcare Partners, Birmingham, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/ERC-16-0118DOI Listing
June 2016

Identification of the microRNA networks contributing to macrophage differentiation and function.

Oncotarget 2016 May;7(20):28806-20

Priority Research Centre for Asthma and Respiratory Diseases, School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle and Hunter Medical Research Institute, Callaghan, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.8933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045358PMC
May 2016

Asthma diagnosis: MicroRNAs to the rescue.

J Allergy Clin Immunol 2016 05;137(5):1447-8

Faculty of Health, School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia; Hunter Medical Research Institute, New Lambton Heights, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.02.013DOI Listing
May 2016

Quantitative electroencephalographic and neuropsychological investigation of an alternative measure of frontal lobe executive functions: the Figure Trail Making Test.

Brain Inform 2015 Dec 26;2(4):239-251. Epub 2015 Nov 26.

Behavioral Neuroscience Laboratory, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40708-015-0025-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883177PMC
December 2015