Paul E Norman

Paul E Norman

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Morphology and Hemodynamics in Isolated Common Iliac Artery Aneurysms Impacts Proximal Aortic Remodeling.

Arterioscler Thromb Vasc Biol 2019 Jun;39(6):1125-1136

From the Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research (L.P.P., L.J.K., B.L., P.E.N., B.J.D.), The University of Western Australia, Perth.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.119.312687
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http://dx.doi.org/10.1161/ATVBAHA.119.312687DOI Listing
June 2019

Cardiovascular Risk Factors Associated With Venous Thromboembolism.

JAMA Cardiol 2019 02;4(2):163-173

London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://cardiology.jamanetwork.com/article.aspx?doi=10.1001/j
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http://dx.doi.org/10.1001/jamacardio.2018.4537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386140PMC
February 2019

Editor's Choice - Metformin Prescription is Associated with a Reduction in the Combined Incidence of Surgical Repair and Rupture Related Mortality in Patients with Abdominal Aortic Aneurysm.

Eur J Vasc Endovasc Surg 2019 Jan 30;57(1):94-101. Epub 2018 Aug 30.

Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia; The Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, Queensland, Australia.

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http://dx.doi.org/10.1016/j.ejvs.2018.07.035DOI Listing
January 2019

Wall Stress and Geometry of the Thoracic Aorta in Patients With Aortic Valve Disease.

Ann Thorac Surg 2018 04 27;105(4):1077-1085. Epub 2017 Dec 27.

British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00034975173166
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http://dx.doi.org/10.1016/j.athoracsur.2017.11.061DOI Listing
April 2018

Plasma free thyroxine in the upper quartile is associated with an increased incidence of major cardiovascular events in older men that do not have thyroid dysfunction according to conventional criteria.

Int J Cardiol 2018 03 29;254:316-321. Epub 2017 Oct 29.

School of Medicine, University of Western Australia, Perth, Australia; Department of Endocrinology, Fiona Stanley Hospital, Perth, Australia.

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http://dx.doi.org/10.1016/j.ijcard.2017.10.100DOI Listing
March 2018

Resveratrol Inhibits Growth of Experimental Abdominal Aortic Aneurysm Associated With Upregulation of Angiotensin-Converting Enzyme 2.

Arterioscler Thromb Vasc Biol 2017 11 21;37(11):2195-2203. Epub 2017 Sep 21.

From the Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, Australia (C.S.M., E.B., S.M.K., S.K.M., J.V.M., J.G.); School of Applied and Biomedical Sciences, Faculty of Science and Technology, Federation University Australia, Mount Helen, Victoria (Y.W.); Department of Diabetes, Central Clinical School, Monash University, Melbourne, Victoria, Australia (C.T., M.E.C., M.C.T.); School of Surgery, Fremantle Hospital, University of Western Australia (P.E.N.); Department of Medicine, University of Melbourne, Austin Hospital, Victoria, Australia (L.M.B.); and Department of Vascular and Endovascular Surgery, Townsville Hospital, Queensland, Australia (J.G.).

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http://dx.doi.org/10.1161/ATVBAHA.117.310129DOI Listing
November 2017

Body Mass Index and Vascular Disease in Men Aged 65 Years and Over: HIMS (Health In Men Study).

J Am Heart Assoc 2017 Nov 27;6(12). Epub 2017 Nov 27.

School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1161/JAHA.117.007343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779044PMC
November 2017

Haemodynamics and stresses in abdominal aortic aneurysms: A fluid-structure interaction study into the effect of proximal neck and iliac bifurcation angle.

J Biomech 2017 07 27;60:150-156. Epub 2017 Jun 27.

Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, and Centre for Medical Research, The University of Western Australia, Perth, Australia; School of Mechanical and Chemical Engineering, The University of Western Australia, Perth, Australia; BHF Centre for Cardiovascular Science, University of Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jbiomech.2017.06.029DOI Listing
July 2017

Systolic Blood Pressure and Vascular Disease in Men Aged 65 Years and Over: The HIMS (Health in Men Study).

Hypertension 2017 06 24;69(6):1053-1059. Epub 2017 Apr 24.

From the Western Australian Centre for Health & Ageing, Centre for Medical Research (B.L., K.A.M., L.F., O.P.A.), School of Medicine and Pharmacology (B.L., B.B.Y., K.A.M., L.F., O.P.A., G.J.H.), School of Surgery (P.E.N.), and School of Psychiatry and Clinical Neurosciences (O.P.A.), University of Western Australia, Crawley; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, United Kingdom (B.L., S.L.); Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, Australia (J.G.); The Department of Vascular and Endovascular Surgery, The Townsville Hospital, Australia (J.G.); Department of Endocrinology and Diabetes, Fiona Stanley and Fremantle Hospitals, Perth, Australia (B.B.Y.); Department of Geriatric Medicine, Royal Perth Hospital, Australia (L.F.); and Department of Neurology, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09150DOI Listing
June 2017

A comparison of hemodynamic metrics and intraluminal thrombus burden in a common iliac artery aneurysm.

Int J Numer Method Biomed Eng 2017 05 8;33(5). Epub 2016 Sep 8.

Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, Perth, WA, Australia.

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http://dx.doi.org/10.1002/cnm.2821DOI Listing
May 2017

Challenges and opportunities in limiting abdominal aortic aneurysm growth.

J Vasc Surg 2017 Jan 15;65(1):225-233. Epub 2016 Sep 15.

Division of Vascular Surgery, Stanford University School of Medicine, Stanford, Calif.

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http://dx.doi.org/10.1016/j.jvs.2016.08.003DOI Listing
January 2017

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

Authors:
Gregory T Jones Gerard Tromp Helena Kuivaniemi Solveig Gretarsdottir Annette F Baas Betti Giusti Ewa Strauss Femke N G Van't Hof Thomas R Webb Robert Erdman Marylyn D Ritchie James R Elmore Anurag Verma Sarah Pendergrass Iftikhar J Kullo Zi Ye Peggy L Peissig Omri Gottesman Shefali S Verma Jennifer Malinowski Laura J Rasmussen-Torvik Kenneth M Borthwick Diane T Smelser David R Crosslin Mariza de Andrade Evan J Ryer Catherine A McCarty Erwin P Böttinger Jennifer A Pacheco Dana C Crawford David S Carrell Glenn S Gerhard David P Franklin David J Carey Victoria L Phillips Michael J A Williams Wenhua Wei Ross Blair Andrew A Hill Thodor M Vasudevan David R Lewis Ian A Thomson Jo Krysa Geraldine B Hill Justin Roake Tony R Merriman Grzegorz Oszkinis Silvia Galora Claudia Saracini Rosanna Abbate Raffaele Pulli Carlo Pratesi Athanasios Saratzis Ana R Verissimo Suzannah Bumpstead Stephen A Badger Rachel E Clough Gillian Cockerill Hany Hafez D Julian A Scott T Simon Futers Simon P R Romaine Katherine Bridge Kathryn J Griffin Marc A Bailey Alberto Smith Matthew M Thompson Frank M van Bockxmeer Stefan E Matthiasson Gudmar Thorleifsson Unnur Thorsteinsdottir Jan D Blankensteijn Joep A W Teijink Cisca Wijmenga Jacqueline de Graaf Lambertus A Kiemeney Jes S Lindholt Anne Hughes Declan T Bradley Kathleen Stirrups Jonathan Golledge Paul E Norman Janet T Powell Steve E Humphries Stephen E Hamby Alison H Goodall Christopher P Nelson Natzi Sakalihasan Audrey Courtois Robert E Ferrell Per Eriksson Lasse Folkersen Anders Franco-Cereceda John D Eicher Andrew D Johnson Christer Betsholtz Arno Ruusalepp Oscar Franzén Eric E Schadt Johan L M Björkegren Leonard Lipovich Anne M Drolet Eric L Verhoeven Clark J Zeebregts Robert H Geelkerken Marc R van Sambeek Steven M van Sterkenburg Jean-Paul de Vries Kari Stefansson John R Thompson Paul I W de Bakker Panos Deloukas Robert D Sayers Seamus C Harrison Andre M van Rij Nilesh J Samani Matthew J Bown

Circ Res 2017 Jan 29;120(2):341-353. Epub 2016 Nov 29.

For the author affiliations, please see the Appendix.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253231PMC
January 2017

Long-term Outcomes of the Western Australian Trial of Screening for Abdominal Aortic Aneurysms: Secondary Analysis of a Randomized Clinical Trial.

JAMA Intern Med 2016 Dec;176(12):1761-1767

School of Surgery, University of Western Australia and Harry Perkins Institute of Medical Research, Fiona Stanley Hospital, Perth.

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http://dx.doi.org/10.1001/jamainternmed.2016.6633DOI Listing
December 2016

The influence of downstream branching arteries on upstream haemodynamics.

J Biomech 2016 09 26;49(13):3090-3096. Epub 2016 Jul 26.

Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, Perth, Australia; School of Mechanical and Chemical Engineering, The University of Western Australia, Australia; Centre for Cardiovascular Science, The University of Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jbiomech.2016.07.023DOI Listing
September 2016

Plasma ferritin concentrations are not associated with abdominal aortic aneurysm diagnosis, size or growth.

Atherosclerosis 2016 08 12;251:19-24. Epub 2016 May 12.

The Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, QLD, 4811, Australia; Department of Vascular and Endovascular Surgery, The Townsville Hospital, Townsville, QLD, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.05.022DOI Listing
August 2016

Association between the Advanced Glycosylation End Product-Specific Receptor Gene and Cardiovascular Death in Older Men.

PLoS One 2015 30;10(7):e0134475. Epub 2015 Jul 30.

Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, Australia; Department of Vascular and Endovascular Surgery, The Townsville Hospital, Townsville, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134475PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520603PMC
May 2016

Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II-Infused Apolipoprotein E-Deficient Mouse.

Arterioscler Thromb Vasc Biol 2016 05 10;36(5):898-907. Epub 2016 Mar 10.

From the Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine & Dentistry (C.S.M., T.D., R.J.J., E.B., J.G.), and Discipline of Biomedicine, College of Public Health, Medical and Veterinary Sciences (C.M.R.), James Cook University, Townsville, Queensland, Australia; Department of Biochemistry, University of Colorado Denver, Aurora (L.G.); School of Surgery, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia (P.E.N.); and Department of Vascular and Endovascular Surgery, The Townsville Hospital, Townsville, Queensland, Australia (J.G.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306945DOI Listing
May 2016

Duration of diabetes and its association with depression in later life: The Health In Men Study (HIMS).

Maturitas 2016 Apr 11;86:3-9. Epub 2016 Jan 11.

WA Centre for Health & Ageing of Centre for Medical Research, Harry Perkins Institute of Medical Research, Perth, Australia; School of Medicine and Pharmacology, University of Western Australia, Perth, Australia; Department of Geriatric Medicine, Royal Perth Hospital, Perth, Australia.

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http://dx.doi.org/10.1016/j.maturitas.2016.01.003DOI Listing
April 2016

Computational Biomechanics in Thoracic Aortic Dissection: Today's Approaches and Tomorrow's Opportunities.

Ann Biomed Eng 2016 Jan 23;44(1):71-83. Epub 2015 Jun 23.

Vascular Engineering, Intelligent Systems for Medicine Laboratory, School of Mechanical and Chemical Engineering, The University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1007/s10439-015-1366-8DOI Listing
January 2016

Mortality among people with severe mental disorders who reach old age: a longitudinal study of a community-representative sample of 37,892 men.

PLoS One 2014 31;9(10):e111882. Epub 2014 Oct 31.

WA Centre for Health & Ageing, Centre for Medical Research, Perth, Australia; School of Medicine and Pharmacology, University of Western Australia, Perth, Australia; Department of Geriatric Medicine, Royal Perth Hospital, Perth, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111882PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216120PMC
December 2015

Temporal changes in the prevalence and associates of diabetes-related lower extremity amputations in patients with type 2 diabetes: the Fremantle Diabetes Study.

Cardiovasc Diabetol 2015 Dec 18;14:152. Epub 2015 Dec 18.

School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, WA, 6959, Australia.

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http://dx.doi.org/10.1186/s12933-015-0315-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683723PMC
December 2015

Proportion of Undercarboxylated Osteocalcin and Serum P1NP Predict Incidence of Myocardial Infarction in Older Men.

J Clin Endocrinol Metab 2015 Oct 26;100(10):3934-42. Epub 2015 Aug 26.

School of Medicine and Pharmacology (B.B.Y., S.A.P.C., C.S., G.J.H., L.F.), University of Western Australia, Perth, Western Australia, Australia; Department of Endocrinology and Diabetes (B.B.Y.), Fiona Stanley Hospital, Perth, Western Australia, Australia; School of Public Health (H.A.), Curtin University, Perth, Western Australia, Australia; PathWest Laboratory Medicine (S.A.P.C., E.B., J.P.B.), Fiona Stanley, Royal Perth and Sir Charles Gairdner Hospitals, Perth, Western Australia, Australia; Department of Medicine (P.R.E.), School for Clinical Sciences, Monash University, Melbourne, Victoria, Australia; Monash Institute of Medical Research (C.A.A.), Prince Henry's Research Institute, Melbourne, Victoria, Australia; Department of Cardiology (C.S.), Royal Perth Hospital, Perth, Western Australia, Australia; Vascular Biology Unit (J.G.), Queensland Research Centre for Peripheral Vascular Disease, School of Medicine, James Cook University, Queensland, Australia; Department of Vascular and Endovascular Surgery (J.G.), The Townsville Hospital, Townsville, Queensland, Australia; Western Australian Centre for Health and Ageing (L.F.), Centre for Medical Research, University of Western Australia, Perth, Western Australia, Australia; School of Surgery (P.E.N.), University of Western Australia, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1210/jc.2015-1899DOI Listing
October 2015

Temporal trends in initial and recurrent lower extremity amputations in people with and without diabetes in Western Australia from 2000 to 2010.

Diabetes Res Clin Pract 2015 May 21;108(2):280-7. Epub 2015 Feb 21.

School of Population Health, Faculty of Medicine, Dentistry and Health Sciences, The University of Western Australia, Australia.

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http://dx.doi.org/10.1016/j.diabres.2015.02.008DOI Listing
May 2015

How many older people are frail? Using multiple imputation to investigate frailty in the population.

J Am Med Dir Assoc 2015 May 14;16(5):439.e1-7. Epub 2015 Mar 14.

Western Australian Centre for Health and Ageing, Centre for Medical Research, University of Western Australia, Crawley, Perth, Western Australia, Australia; School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.jamda.2015.02.003DOI Listing
May 2015

Depression, frailty, and all-cause mortality: a cohort study of men older than 75 years.

J Am Med Dir Assoc 2015 Apr 10;16(4):296-300. Epub 2014 Dec 10.

WA Center for Health and Aging, Center for Medical Research, Perth, Australia; School of Medicine and Pharmacology, University of Western Australia, Perth, Australia; Department of Geriatric Medicine, Royal Perth Hospital, Perth, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S15258610140070
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http://dx.doi.org/10.1016/j.jamda.2014.10.023DOI Listing
April 2015

Temporal changes in the prevalence and associates of foot ulceration in type 2 diabetes: the Fremantle Diabetes Study.

J Diabetes Complications 2015 Apr 19;29(3):356-61. Epub 2015 Jan 19.

School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jdiacomp.2015.01.008DOI Listing
April 2015

Diabetes, myocardial infarction and stroke are distinct and duration-dependent predictors of subsequent cardiovascular events and all-cause mortality in older men.

J Clin Endocrinol Metab 2015 Mar 30;100(3):1038-47. Epub 2014 Dec 30.

School of Medicine and Pharmacology (B.B.Y., L.F., G.J.H.), University of Western Australia, Perth, Western Australia 6009, Department of Endocrinology and Diabetes (B.B.Y.), Fremantle and Fiona Stanley Hospitals, Perth, Western Australia 6160, Western Australian Centre for Health and Ageing (O.P.A., K.A.M., L.F.), Centre for Medical Research, University of Western Australia, Perth, Western Australia 6000, Department of Neurology (G.J.H.), Sir Charles Gairdner Hospital, Perth, Western Australia 6009, School of Psychiatry and Clinical Neurosciences (O.P.A.), University of Western Australia, Perth, Western Australia 6009, Queensland Research Centre for Peripheral Vascular Disease (J.G.), School of Medicine and Dentistry, James Cook University, Townsville, Queensland 4811; School of Surgery (P.E.N.), University of Western Australia, Perth, Western Australia 6009, Australia.

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http://dx.doi.org/10.1210/jc.2014-3339DOI Listing
March 2015

Serum endostatin concentrations are higher in men with symptoms of intermittent claudication.

Dis Markers 2014 30;2014:298239. Epub 2014 Jan 30.

School of Surgery, University of Western Australia, Perth, WA 6907, Australia.

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http://dx.doi.org/10.1155/2014/298239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926361PMC
January 2015

Higher serum undercarboxylated osteocalcin and other bone turnover markers are associated with reduced diabetes risk and lower estradiol concentrations in older men.

J Clin Endocrinol Metab 2015 Jan;100(1):63-71

Schools of Medicine and Pharmacology (B.B.Y., S.A.P.C., L.F.) and Surgery (P.E.N.) and Western Australian Centre for Health and Ageing (L.F.), Centre for Medical Research, University of Western Australia, Perth, Western Australia 6009, Australia; Department of Endocrinology and Diabetes (B.B.Y., R.G.), Fremantle and Fiona Stanley Hospitals, Perth, Western Australia 6160, Australia; School of Public Health (H.A.), Curtin University, Perth, Western Australia 6102, Australia; PathWest Laboratory Medicine (S.A.P.C., J.P.B.), Fremantle, Royal Perth and Sir Charles Gairdner Hospitals, Perth, Western Australia 6160, Australia; Department of Medicine (P.R.E.), School for Clinical Sciences, Monash University, Melbourne, Victoria 3800, Australia; ANZAC Research Institute (D.J.H.), University of Sydney, Sydney, New South Wales 2139, Australia; Monash Institute of Medical Research (C.A.A.), Prince Henry's Research Institute, Melbourne, Victoria 3168, Australia; and Department of Medicine (M.G.), Austin Health, University of Melbourne, Melbourne, Victoria, 3084 Australia.

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http://dx.doi.org/10.1210/jc.2014-3019DOI Listing
January 2015

In older men, higher plasma testosterone or dihydrotestosterone is an independent predictor for reduced incidence of stroke but not myocardial infarction.

J Clin Endocrinol Metab 2014 Dec;99(12):4565-73

School of Medicine and Pharmacology (B.B.Y., S.A.P.C., G.J.H., L.F.), Western Australian Centre for Health and Ageing (H.A., O.P.A., L.F.), Centre for Medical Research, School of Psychiatry and Clinical Neurosciences (O.P.A.), and School of Surgery (P.E.N.), University of Western Australia, Perth, Western Australia 6009, Australia; Department of Endocrinology and Diabetes (B.B.Y.), Fremantle and Fiona Stanley Hospitals, Perth, Western Australia 6160, Australia; School of Public Health (H.A.), Curtin University, Perth, Western Australia 6102, Australia; PathWest Laboratory Medicine (S.A.P.C.), Fremantle and Royal Perth Hospitals, Perth, Western Australia 6160, Australia; ANZAC Research Institute (D.J.H.), University of Sydney, Sydney, New South Wales 2139, Australia; Vascular Biology Unit (J.G.), Queensland Research Centre for Peripheral Vascular Disease, School of Medicine, James Cook University, Brisbane, Queensland 4811, Australia; and Department of Vascular and Endovascular Surgery (J.G.), Townsville Hospital, Townsville, Queensland 4814, Australia.

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http://dx.doi.org/10.1210/jc.2014-2664DOI Listing
December 2014

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Authors:
Michael V Holmes Caroline E Dale Luisa Zuccolo Richard J Silverwood Yiran Guo Zheng Ye David Prieto-Merino Abbas Dehghan Stella Trompet Andrew Wong Alana Cavadino Dagmar Drogan Sandosh Padmanabhan Shanshan Li Ajay Yesupriya Maarten Leusink Johan Sundstrom Jaroslav A Hubacek Hynek Pikhart Daniel I Swerdlow Andrie G Panayiotou Svetlana A Borinskaya Chris Finan Sonia Shah Karoline B Kuchenbaecker Tina Shah Jorgen Engmann Lasse Folkersen Per Eriksson Fulvio Ricceri Olle Melander Carlotta Sacerdote Dale M Gamble Sruti Rayaprolu Owen A Ross Stela McLachlan Olga Vikhireva Ivonne Sluijs Robert A Scott Vera Adamkova Leon Flicker Frank M van Bockxmeer Christine Power Pedro Marques-Vidal Tom Meade Michael G Marmot Jose M Ferro Sofia Paulos-Pinheiro Steve E Humphries Philippa J Talmud Irene Mateo Leach Niek Verweij Allan Linneberg Tea Skaaby Pieter A Doevendans Maarten J Cramer Pim van der Harst Olaf H Klungel Nicole F Dowling Anna F Dominiczak Meena Kumari Andrew N Nicolaides Cornelia Weikert Heiner Boeing Shah Ebrahim Tom R Gaunt Jackie F Price Lars Lannfelt Anne Peasey Ruzena Kubinova Andrzej Pajak Sofia Malyutina Mikhail I Voevoda Abdonas Tamosiunas Anke H Maitland-van der Zee Paul E Norman Graeme J Hankey Manuela M Bergmann Albert Hofman Oscar H Franco Jackie Cooper Jutta Palmen Wilko Spiering Pim A de Jong Diana Kuh Rebecca Hardy Andre G Uitterlinden M Arfan Ikram Ian Ford Elina Hyppönen Osvaldo P Almeida Nicholas J Wareham Kay-Tee Khaw Anders Hamsten Lise Lotte N Husemoen Anne Tjønneland Janne S Tolstrup Eric Rimm Joline W J Beulens W M Monique Verschuren N Charlotte Onland-Moret Marten H Hofker S Goya Wannamethee Peter H Whincup Richard Morris Astrid M Vicente Hugh Watkins Martin Farrall J Wouter Jukema James Meschia L Adrienne Cupples Stephen J Sharp Myriam Fornage Charles Kooperberg Andrea Z LaCroix James Y Dai Matthew B Lanktree David S Siscovick Eric Jorgenson Bonnie Spring Josef Coresh Yun R Li Sarah G Buxbaum Pamela J Schreiner R Curtis Ellison Michael Y Tsai Sanjay R Patel Susan Redline Andrew D Johnson Ron C Hoogeveen Hakon Hakonarson Jerome I Rotter Eric Boerwinkle Paul I W de Bakker Mika Kivimaki Folkert W Asselbergs Naveed Sattar Debbie A Lawlor John Whittaker George Davey Smith Kenneth Mukamal Bruce M Psaty James G Wilson Leslie A Lange Ajna Hamidovic Aroon D Hingorani Børge G Nordestgaard Martin Bobak David A Leon Claudia Langenberg Tom M Palmer Alex P Reiner Brendan J Keating Frank Dudbridge Juan P Casas

BMJ 2014 Jul 10;349:g4164. Epub 2014 Jul 10.

Genetic Epidemiology Group, Institute of Cardiovascular Science, Department of Epidemiology and Public Health, University College London, UK Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091648PMC
http://dx.doi.org/10.1136/bmj.g4164DOI Listing
July 2014

Regions of high wall stress can predict the future location of rupture of abdominal aortic aneurysm.

Cardiovasc Intervent Radiol 2014 Jun 20;37(3):815-8. Epub 2014 Feb 20.

Intelligent Systems for Medicine Laboratory, School of Mechanical and Chemical Engineering, The University of Western Australia, 35 Stirling Highway, Perth, WA, Australia,

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http://dx.doi.org/10.1007/s00270-014-0864-7DOI Listing
June 2014

Partial foot amputations may not always be worth the risk of complications.

Med J Aust 2014 Jun;200(11):634, 636

University of Western Australia, Perth, WA, Australia.

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June 2014

Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence.

Stroke 2014 Apr 25;45(4):1064-8. Epub 2014 Feb 25.

From the Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Australia (J.G., P.C.); Department of Vascular and Endovascular Surgery, The Townsville Hospital, Townsville, Australia (J.G.); Faculty of Health and Medicine, School of Nursing and Midwifery (J.M.) and Faculty of Health, School of Health Sciences (C.L., J.S.), The University of Newcastle, Newcastle, Australia; The Hunter Medical Research Institute, Newcastle, New South Wales, Australia (J.M., L.L., M.M., J.A.); Hunter Haematology Research Group, Calvary Mater Newcastle, Waratah, New South Wales, Australia (L.L.); Stroke Research Programme, University of Adelaide, The Queen Elizabeth Hospital campus, Adelaide, Australia (S.K.); The Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, New South Wales, Australia (M.M., J.A.); Department of Neurosciences, Central Coast Health District, Gosford, New South Wales, Australia (J.S.); School of Psychiatry and Clinical Neurosciences (O.P.A.), School of Medicine and Pharmacology (B.B.Y.), Western Australian Centre for Health and Ageing, Centre for Medical Research (L.F.), School of Surgery (P.E.N.), and School of Medicine and Pharmacology (G.J.H.), University of Western Australia, Perth, Western Australia, Australia; and Department of Endocrinology and Diabetes, Fremantle Hospital, Fremantle, Australia (B.B.Y.).

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http://dx.doi.org/10.1161/STROKEAHA.113.004339DOI Listing
April 2014

In older men an optimal plasma testosterone is associated with reduced all-cause mortality and higher dihydrotestosterone with reduced ischemic heart disease mortality, while estradiol levels do not predict mortality.

J Clin Endocrinol Metab 2014 Jan 20;99(1):E9-18. Epub 2013 Dec 20.

School of Medicine and Pharmacology (B.B.Y., S.A.P.C., G.J.H., L.F.), University of Western Australia, Perth, Western Australia 6009, Australia; Department of Endocrinology and Diabetes (B.B.Y.), Fremantle Hospital, Fremantle, Western Australia 6160, Australia; Western Australian Centre for Health and Ageing (H.A., O.P.A., L.F.), Centre for Medical Research, University of Western Australia, Perth, Western Australia 6009, Australia; PathWest Laboratory Medicine (S.A.P.C.), Fremantle and Royal Perth Hospitals, Perth, Western Australia 6009, Australia; ANZAC Research Institute (D.J.H.), University of Sydney, Sydney, New South Wales 2139, Australia; School of Psychiatry and Clinical Neurosciences (O.P.A.), University of Western Australia, Perth, Western Australia 6009, Australia; Vascular Biology Unit (J.G.), Queensland Research Centre for Peripheral Vascular Disease, School of Medicine, James Cook University, Townsville, Queensland 4811, Australia; and School of Surgery (P.E.N.), University of Western Australia, Perth, Western Australia 6009, Australia.

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http://dx.doi.org/10.1210/jc.2013-3272DOI Listing
January 2014

Lower plasma testosterone or dihydrotestosterone, but not estradiol, is associated with symptoms of intermittent claudication in older men.

Clin Endocrinol (Oxf) 2013 Nov 13;79(5):725-32. Epub 2013 Apr 13.

School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia; Department of Endocrinology and Diabetes, Fremantle Hospital, Fremantle, WA, Australia.

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http://dx.doi.org/10.1111/cen.12208DOI Listing
November 2013

Higher free thyroxine levels are associated with all-cause mortality in euthyroid older men: the Health In Men Study.

Eur J Endocrinol 2013 Oct 12;169(4):401-8. Epub 2013 Sep 12.

School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia.

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October 2013

Increased serum angiopoietin-2 is associated with abdominal aortic aneurysm prevalence and cardiovascular mortality in older men.

Int J Cardiol 2013 Aug 6;167(4):1159-63. Epub 2012 Apr 6.

Vascular Biology Unit, School of Medicine and Dentistry, James Cook University, Townsville, Australia.

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http://dx.doi.org/10.1016/j.ijcard.2012.03.120DOI Listing
August 2013

Plasma total homocysteine is associated with abdominal aortic aneurysm and aortic diameter in older men.

J Vasc Surg 2013 Aug 3;58(2):364-70. Epub 2013 May 3.

Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.jvs.2013.01.046DOI Listing
August 2013

Understanding the effects of tobacco smoke on the pathogenesis of aortic aneurysm.

Arterioscler Thromb Vasc Biol 2013 Jul 16;33(7):1473-7. Epub 2013 May 16.

School of Surgery, University of Western Australia, Fremantle, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683352PMC
July 2013

The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation.

Atherosclerosis 2013 Jun 26;228(2):295-305. Epub 2013 Feb 26.

The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, James Cook Drive, Douglas, Townsville, QLD 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.02.019DOI Listing
June 2013

Relation between serum thrombospondin-2 and cardiovascular mortality in older men screened for abdominal aortic aneurysm.

Am J Cardiol 2013 Jun 22;111(12):1800-4. Epub 2013 Mar 22.

Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, Townsville, Australia.

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http://dx.doi.org/10.1016/j.amjcard.2013.02.038DOI Listing
June 2013

Total joint replacement in men: old age, obesity and in-hospital complications.

ANZ J Surg 2013 May 11;83(5):376-81. Epub 2012 Sep 11.

School of Population Health and Clinical Practice, Discipline of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1111/j.1445-2197.2012.06227.xDOI Listing
May 2013

Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes.

Arterioscler Thromb Vasc Biol 2013 Apr 7;33(4):814-21. Epub 2013 Feb 7.

Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University Townsville, QLD, Australia.

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http://dx.doi.org/10.1161/ATVBAHA.112.301006DOI Listing
April 2013

Older men who use computers have lower risk of dementia.

PLoS One 2012 28;7(8):e44239. Epub 2012 Aug 28.

School of Psychiatry & Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429429PMC
February 2013

Reference ranges and determinants of testosterone, dihydrotestosterone, and estradiol levels measured using liquid chromatography-tandem mass spectrometry in a population-based cohort of older men.

J Clin Endocrinol Metab 2012 Nov 13;97(11):4030-9. Epub 2012 Sep 13.

School of Medicine and Pharmacology, Level 2, T Block, Fremantle Hospital, Alma Street, Fremantle, Western Australia 6160, Australia.

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http://dx.doi.org/10.1210/jc.2012-2265DOI Listing
November 2012

Temporal trends in the incidence and recurrence of hospitalised atherothrombotic disease in an Australian population, 2000-07: data linkage study.

Heart 2012 Oct 21;98(19):1449-56. Epub 2012 Jul 21.

School of Population Health, M431, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia.

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http://dx.doi.org/10.1136/heartjnl-2012-302181DOI Listing
October 2012

A large-scale replication study for the association of rs17039192 in HIF-2α with knee osteoarthritis.

J Orthop Res 2012 Aug 13;30(8):1244-8. Epub 2012 Jan 13.

Laboratory for Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Tokyo, Japan.

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http://dx.doi.org/10.1002/jor.22063DOI Listing
August 2012

Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model.

Am J Pathol 2012 Aug 12;181(2):706-18. Epub 2012 Jun 12.

Vascular Biology Unit, School of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia.

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http://dx.doi.org/10.1016/j.ajpath.2012.04.015DOI Listing
August 2012

Cardiovascular disease, depression and mortality: the Health In Men Study.

Am J Geriatr Psychiatry 2012 May;20(5):433-40

Western Australia Centre for Health & Ageing, University of Western Australia, Australia.

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http://dx.doi.org/10.1097/JGP.0b013e318211c1edDOI Listing
May 2012

CRP 1846G>A polymorphism increases risk of frailty.

Maturitas 2012 Mar 20;71(3):261-6. Epub 2011 Dec 20.

Western Australian Centre for Health & Ageing, Western Australian Institute for Medical Research, Australia.

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http://dx.doi.org/10.1016/j.maturitas.2011.11.022DOI Listing
March 2012

Associations of IGF1 and its binding proteins with abdominal aortic aneurysm and aortic diameter in older men.

Eur J Endocrinol 2012 Feb 23;166(2):191-7. Epub 2011 Nov 23.

School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1530/EJE-11-0725DOI Listing
February 2012

The association between the gene encoding 5-lipoxygenase activating protein and abdominal aortic aneurysms.

Atherosclerosis 2012 Feb 9;220(2):425-8. Epub 2011 Nov 9.

Department of Clinical Immunology and Rheumatology, Academic Medical Center, PO Box 22660, 1100 DD Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.10.040DOI Listing
February 2012

Plasma homocysteine and MTHFRC677T polymorphism as risk factors for incident dementia.

J Neurol Neurosurg Psychiatry 2012 Jan 11;83(1):70-5. Epub 2011 Jul 11.

School of Psychiatry & Clinical Neurosciences (M573), University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.

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http://dx.doi.org/10.1136/jnnp.2011.242446DOI Listing
January 2012

Accuracy of hospital morbidity data and the performance of comorbidity scores as predictors of mortality.

J Clin Epidemiol 2012 Jan 31;65(1):107-15. Epub 2011 Jul 31.

School of Population Health and Clinical Practice, Discipline of Public Health, The University of Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1016/j.jclinepi.2011.03.014DOI Listing
January 2012

Low free testosterone predicts mortality from cardiovascular disease but not other causes: the Health in Men Study.

J Clin Endocrinol Metab 2012 Jan 19;97(1):179-89. Epub 2011 Oct 19.

Western Australian Centre for Health and Ageing, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia.

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http://dx.doi.org/10.1210/jc.2011-1617DOI Listing
January 2012

Proteomic analysis of intra-arterial thrombus secretions reveals a negative association of clusterin and thrombospondin-1 with abdominal aortic aneurysm.

Atherosclerosis 2011 Dec 22;219(2):432-9. Epub 2011 Aug 22.

Vascular Biology Unit, School of Medicine and Dentistry, James Cook University, Angus Smith Drive, Douglas, Townsville, QLD 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.08.013DOI Listing
December 2011

The cardiovascular and prognostic significance of the infrarenal aortic diameter.

J Vasc Surg 2011 Dec 23;54(6):1817-20. Epub 2011 Sep 23.

School of Surgery, University of Western Australia, Fremantle, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.jvs.2011.07.048DOI Listing
December 2011

Meta-analysis of the association between single nucleotide polymorphisms in TGF-β receptor genes and abdominal aortic aneurysm.

Atherosclerosis 2011 Nov 30;219(1):218-23. Epub 2011 Jul 30.

Vascular Biology Unit, School of Medicine, James Cook University, Townsville, Queensland 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.07.105DOI Listing
November 2011

A single nucleotide polymorphism in exon 3 of the kallikrein 1 gene is associated with large but not small abdominal aortic aneurysm.

Atherosclerosis 2011 Aug 22;217(2):452-7. Epub 2011 Apr 22.

Vascular Biology Unit, School of Medicine, James Cook University, Townsville, Queensland 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.04.017DOI Listing
August 2011

Falls, injuries from falls, health related quality of life and mortality in older adults with vision and hearing impairment--is there a gender difference?

Maturitas 2011 Aug 12;69(4):359-64. Epub 2011 Jun 12.

Western Australian Centre for Health and Ageing (WACHA), Centre for Medical Research, The University of Western Australia, Nedlands, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.maturitas.2011.05.006DOI Listing
August 2011

Smoking, body weight, physical exercise, and risk of lower limb total joint replacement in a population-based cohort of men.

Arthritis Rheum 2011 Aug;63(8):2523-30

School of Population Health and Clinical Practice, Discipline of Public Health, University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1002/art.30400DOI Listing
August 2011

Current status of medical management for abdominal aortic aneurysm.

Atherosclerosis 2011 Jul 10;217(1):57-63. Epub 2011 Mar 10.

Vascular Biology Unit, Department of Surgery, School of Medicine and Dentistry, James Cook University, Townsville, QLD 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.03.006DOI Listing
July 2011

Serum secreted phospholipase A2 is associated with abdominal aortic aneurysm presence but not progression.

Atherosclerosis 2011 Jun 18;216(2):458-60. Epub 2011 Feb 18.

Vascular Biology Unit, School of Medicine and Dentistry, James Cook University, Townsville 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.02.022DOI Listing
June 2011

Associations of IGF1 and IGFBPs 1 and 3 with all-cause and cardiovascular mortality in older men: the Health In Men Study.

Eur J Endocrinol 2011 May 4;164(5):715-23. Epub 2011 Mar 4.

School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1530/EJE-11-0059DOI Listing
May 2011

Elevated LH predicts ischaemic heart disease events in older men: the Health in Men Study.

Eur J Endocrinol 2011 Apr 1;164(4):569-77. Epub 2011 Feb 1.

Western Australian Centre for Health and Ageing (M570), Centre for Medical Research, Western Australian Institute for Medical Research School of Medicine and Pharmacology School of Surgery, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia.

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http://dx.doi.org/10.1530/EJE-10-1063DOI Listing
April 2011

Traditional risk factors for incident cardiovascular events have limited importance in later life compared with the health in men study cardiovascular risk score.

Stroke 2011 Apr 10;42(4):952-9. Epub 2011 Feb 10.

Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, Perth, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.110.603480DOI Listing
April 2011

A population-based study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm.

Eur J Hum Genet 2011 Mar 1;19(3):363-6. Epub 2010 Dec 1.

Vascular Biology Unit, Department of Surgery, School of Medicine, James Cook University, Townsville, Queensland, Australia.

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http://dx.doi.org/10.1038/ejhg.2010.182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062004PMC
March 2011

Evaluation of the diagnostic and prognostic value of plasma D-dimer for abdominal aortic aneurysm.

Eur Heart J 2011 Feb 8;32(3):354-64. Epub 2010 Jun 8.

Vascular Biology Unit, School of Medicine and Dentistry, James Cook University, Townsville QLD 4811, Australia.

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http://dx.doi.org/10.1093/eurheartj/ehq171DOI Listing
February 2011

Falling rates of hospitalization and mortality from abdominal aortic aneurysms in Australia.

J Vasc Surg 2011 Feb 4;53(2):274-7. Epub 2010 Nov 4.

School of Surgery, University of Western Australia, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.jvs.2010.08.087DOI Listing
February 2011

Data openness. Absolute v relative risk reduction.

Authors:
Paul E Norman

BMJ 2010 Nov 16;341:c6333. Epub 2010 Nov 16.

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http://dx.doi.org/10.1136/bmj.c6333DOI Listing
November 2010

Association of an allele on chromosome 9 and abdominal aortic aneurysm.

Atherosclerosis 2010 Oct 15;212(2):539-42. Epub 2010 Jun 15.

Vascular Biology Unit, School of Medicine, James Cook University, Townsville, Queensland 4811, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952706PMC
October 2010

Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels.

Eur J Endocrinol 2010 Aug 25;163(2):265-72. Epub 2010 May 25.

School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia 6009, Australia.

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http://dx.doi.org/10.1530/EJE-10-0414DOI Listing
August 2010

Population-based observational study of claudication in older men: the Health in Men Study.

Med J Aust 2010 Jun;192(11):641-5

University of Western Australia, Fremantle Hospital, Fremantle, WA, Australia.

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June 2010

Association between serum lipoproteins and abdominal aortic aneurysm.

Am J Cardiol 2010 May 30;105(10):1480-4. Epub 2010 Mar 30.

Vascular Biology Unit, James Cook University School of Medicine, Townsville, Queensland, Australia.

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http://dx.doi.org/10.1016/j.amjcard.2009.12.076DOI Listing
May 2010