Publications by authors named "Paul E Keck"

95Publications

Double jeopardy in the United States: Early onset bipolar disorder and treatment delay.

Psychiatry Res 2020 10 3;292:113274. Epub 2020 Jul 3.

University Medical Center, University of Groningen, Groningen, the Netherlands.

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October 2020

Adding Increased Energy or Activity to Criterion (A) of the DSM-5 Definition of Hypomania and Mania: Effect on the Diagnoses of 907 Patients From the Bipolar Collaborative Network.

J Clin Psychiatry 2019 10 29;80(6). Epub 2019 Oct 29.

Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, VA Palo Alto Health Care System, 3801 Miranda Ave (151 T), Palo Alto, CA 94304.

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October 2019

Testing a clinical staging model for bipolar disorder using longitudinal life chart data.

Bipolar Disord 2019 05 12;21(3):228-234. Epub 2018 Dec 12.

Department of Psychiatry, Amsterdam Public Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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May 2019

Testing a clinical staging model for bipolar disorder using longitudinal life chart data.

Bipolar Disord 2019 05 12;21(3):228-234. Epub 2018 Dec 12.

Department of Psychiatry, Amsterdam Public Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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May 2019

Testing a clinical staging model for bipolar disorder using longitudinal life chart data.

Bipolar Disord 2019 05 12;21(3):228-234. Epub 2018 Dec 12.

Department of Psychiatry, Amsterdam Public Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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May 2019

Would glucagon-like peptide-1 receptor agonists have efficacy in binge eating disorder and bulimia nervosa? A review of the current literature.

Med Hypotheses 2018 Feb 2;111:90-93. Epub 2018 Jan 2.

Lindner Center of HOPE, Mason, OH, USA; University of Cincinnati College of Medicine Department of Psychiatry and Behavioral Neuroscience, Cincinnati, OH, USA.

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February 2018

Medical comorbidity of binge eating disorder: response.

Eat Weight Disord 2017 12 13;22(4):725-726. Epub 2017 May 13.

Lindner Center of HOPE, Mason, USA.

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December 2017

Switch Rates During Acute Treatment for Bipolar II Depression With Lithium, Sertraline, or the Two Combined: A Randomized Double-Blind Comparison.

Am J Psychiatry 2017 Mar 31;174(3):266-276. Epub 2017 Jan 31.

From the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles; the Jane and Terry Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles; the Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, Los Angeles; the Department of Biostatistics, School of Public Health, University of California, Los Angeles; the Lindner Center of HOPE, Mason, Ohio; the Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati; the Department of Psychiatry and Biobehavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the VA Palo Alto Health Care System, Palo Alto, Calif.; and the Department of Psychiatry, Olive View-UCLA Medical Center, Sylmar, Calif.

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March 2017

Dysphoric mania, mixed states, and mania with mixed features specifier: are we mixing things up?

CNS Spectr 2017 Apr 21;22(2):170-176. Epub 2016 Nov 21.

1Lindner Center of HOPE,Mason,Ohio,USA.

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April 2017

Dysphoric mania, mixed states, and mania with mixed features specifier: are we mixing things up?

CNS Spectr 2017 Apr 21;22(2):170-176. Epub 2016 Nov 21.

1Lindner Center of HOPE,Mason,Ohio,USA.

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April 2017

Medical comorbidity of binge eating disorder.

Eat Weight Disord 2017 Mar 23;22(1):13-26. Epub 2016 Aug 23.

Lindner Center of HOPE, 4075 Old Western Row Road, Mason, OH, 45040, USA.

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March 2017

Managing comorbid obesity and depression through clinical pharmacotherapies.

Expert Opin Pharmacother 2016 Aug 24;17(12):1599-610. Epub 2016 Jun 24.

a Research Institute , Lindner Center of HOPE , Mason , OH , USA.

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August 2016

Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network.

Am J Psychiatry 2016 Oct 15;173(10):1015-1023. Epub 2016 Apr 15.

From the VA Palo Alto Health Care System, Palo Alto, and the Department of Psychiatry and Behavioral Sciences, Stanford University Medical Center, Stanford, Calif.; the Department of Psychiatry, University of Texas Health Science Center, San Antonio; the Department of Psychiatry, UCLA, Los Angeles; the Department of Psychiatry, Mayo Clinic, Rochester, Minn.; the Lindner Center of HOPE, University of Cincinnati, Mason, Ohio; University Medical Center Groningen, University of Groningen, the Netherlands; the Altrecht Institute for Mental Health Care, Utrecht, and VU University Medical Centre Amsterdam, VU University Amsterdam, the Netherlands; the Biological Psychiatry Branch, NIMH, Bethesda, Md.; the Department of Psychiatry and Psychotherapy, Paracelsus Medical University, and Christian Doppler Klinik, Salzburg, Austria; and the School of Medicine and Health Sciences, George Washington University, Washington, D.C.

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October 2016

Overview of the treatment of binge eating disorder.

CNS Spectr 2015 Dec;20(6):546-56

Linder Center of HOPE,Mason,Ohio,USA;Department of Psychiatry and Behavioral Neuroscience,University of Cincinnati College of Medicine,Cincinnati,Ohio,USA.

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December 2015

Communication between physicians and patients with suspected or diagnosed binge eating disorder.

Postgrad Med 2015 ;127(7):661-70

a 1 Department of Psychiatry and Institute for Women's Health, Virginia Commonwealth University , Richmond, VA 23219, USA.

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November 2015

Multigenerational Positive Family History of Psychiatric Disorders Is Associated With a Poor Prognosis in Bipolar Disorder.

J Neuropsychiatry Clin Neurosci 2015 10;27(4):304-10. Epub 2015 Aug 10.

From the Bipolar Collaborative Network, Bethesda, MD (RMP, MR, GSL); Dept. of Psychiatry and Behavioral Sciences, George Washington University, Washington, DC (RMP); Dept. of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, CA (LA); Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, Los Angeles, CA (LA); Dept. of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands (RK); Lindner Center of HOPE, Mason, OH (SLM, PEK); Biological Psychiatry Program, University of Cincinnati Medical College, Cincinnati, OH (SLM); Dept. of Psychiatry, Mayo Clinic, Rochester, MN (MAF); Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom (HG); Dept. of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA (TS); VA Palo Alto Health Care System, Palo Alto, CA (TS); Dept. of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH (PEK); and University Medical Center, University of Groningen, Groningen, the Netherlands (WAN).

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September 2016

Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany.

Psychiatr Genet 2015 Oct;25(5):194-200

aBipolar Collaborative Network, Bethesda, Maryland bDepartment of Psychiatry and Behavioral Sciences, George Washington University, Washington, District of Columbia cDepartment of Psychiatry and Behavioral Neuroscience dDepartment of Psychiatry and Behavioral Neuroscience, Biological Psychiatry Program, University of Cincinnati Medical College, Cincinnati eLindner Center of HOPE, Mason, Ohio fDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California gDepartment of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, Los Angeles hDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine iV.A. Palo Alto HealthCare System, Palo Alto, California jDepartment of Psychiatry, Mayo Clinic, Rochester, Michigan, USA kDepartment of Psychiatry, VU University Medical Center, Amsterdam lDepartment of Psychiatry, University Medical Center, University of Groningen, Groningen, The Netherlands mDepartment of Psychiatry and Psychotherapy, Christian Doppler Klink, Paracelsus Medical University Salzburg, Austria.

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October 2015

Armodafinil in binge eating disorder: a randomized, placebo-controlled trial.

Int Clin Psychopharmacol 2015 Jul;30(4):209-15

aLindner Center of HOPE, Mason bDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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July 2015

Adjunctive lisdexamfetamine in bipolar depression: a preliminary randomized, placebo-controlled trial.

Int Clin Psychopharmacol 2015 Jan;30(1):6-13

aLindner Center of HOPE, Mason bDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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January 2015

Verbal abuse, like physical and sexual abuse, in childhood is associated with an earlier onset and more difficult course of bipolar disorder.

Bipolar Disord 2015 May 13;17(3):323-30. Epub 2014 Oct 13.

Department of Psychiatry and Behavioral Sciences, George Washington University, Washington, DC; Bipolar Collaborative Network, Bethesda, MD.

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May 2015

Monitoring pharmacotherapy response, safety, and tolerability to enhance adherence in bipolar disorder.

Authors:
Paul E Keck

J Clin Psychiatry 2014 May;75(5):e12

From the Lindner Center of HOPE, Mason, and the Department of Psychiatry and Neuroscience, University of Cincinnati, Cincinnati, Ohio.

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May 2014

More medical comorbidities in patients with bipolar disorder from the United States than from the Netherlands and Germany.

J Nerv Ment Dis 2014 Apr;202(4):265-70

*Bipolar Collaborative Network, Bethesda, MD; †UCLA Mood Disorders Research Program and VA Medical Center, Los Angeles, CA; ‡Mayo Clinic Department of Psychiatry and Psychology, Mayo Clinic Depression Center, Rochester, MI; §Department of Psychiatry, SW Medical Center, University of Texas, Dallas, TX; ∥Linder Center of Hope, Mason, OH; ¶Biological Psychiatry Program, University of Cincinnati Medical College, Cincinnati, OH; #University Medical Center Groningen (UMCG), University of Groningen, Groningen, the Netherlands; **Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands; and ††Newcastle University, Institute of Neuroscience, Newcastle upon Tyne, UK.

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April 2014

Metabolic syndrome in bipolar disorder: a review with a focus on bipolar depression.

J Clin Psychiatry 2014 Jan;75(1):46-61

Lindner Center of HOPE, 4075 Old Western Row Rd, Mason, OH 45050

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January 2014

Placebo response in binge eating disorder: a pooled analysis of 10 clinical trials from one research group.

Eur Eat Disord Rev 2014 Mar 8;22(2):140-6. Epub 2014 Jan 8.

Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Lindner Center of HOPE, Mason, OH, USA.

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March 2014

Illness progression as a function of independent and accumulating poor prognosis factors in outpatients with bipolar disorder in the United States.

Prim Care Companion CNS Disord 2014 18;16(6). Epub 2014 Dec 18.

Bipolar Collaborative Network, Bethesda, Maryland (Drs Post and Rowe and Mr Leverich); UCLA Mood Disorders Research Program and VA Medical Center, Los Angeles (Dr Altshuler); Universitair Medisch Centrum Groningen (UMCG), Groningen, The Netherlands (Dr Nolen); Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands (Dr Kupka); Newcastle University, Institute of Neuroscience, Newcastle upon Tyne, United Kingdom (Mr Grunze); Department of Psychiatry, Mayo Clinic, Rochester, Minnesota (Dr Frye); Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto and VA Palo Alto Health Care System, Palo Alto, California (Dr Suppes); Lindner Center of HOPE, Mason, Ohio and Biological Psychiatry Program, University of Cincinnati Medical College, Cincinnati, Ohio (Dr McElroy); and Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio and Lindner Center of HOPE, Mason, Ohio (Dr Keck).

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April 2015

Heritability and linkage analysis of personality in bipolar disorder.

J Affect Disord 2013 Nov 22;151(2):748-755. Epub 2013 Aug 22.

Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, Mail Code 0737, La Jolla, CA 92093, USA; San Diego Veterans Affairs Healthcare System, San Diego, CA, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA, USA.

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November 2013

Zonisamide in the treatment of bulimia nervosa: an open-label, pilot, prospective study.

Int J Eat Disord 2013 Nov 25;46(7):747-50. Epub 2013 Jul 25.

Lindner Center of HOPE, Mason, Ohio; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio.

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November 2013

Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder.

J Affect Disord 2013 Sep 10;150(3):1031-40. Epub 2013 Jun 10.

Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA.

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September 2013

Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder.

J Affect Disord 2013 Sep 10;150(3):1031-40. Epub 2013 Jun 10.

Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA.

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September 2013

Association of dopamine transporter gene variants with childhood ADHD features in bipolar disorder.

Am J Med Genet B Neuropsychiatr Genet 2013 Mar 19;162B(2):137-45. Epub 2012 Dec 19.

Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA.

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March 2013

Exposure to potentially dangerous drug-drug interactions involving antipsychotics.

Psychiatr Serv 2012 Nov;63(11):1080-8

Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of Cincinnati Medical Center, 3225 Eden Ave., Cincinnati, OH 45267, USA.

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November 2012

Obesity in bipolar disorder: an overview.

Curr Psychiatry Rep 2012 Dec;14(6):650-8

Lindner Center of HOPE, 4075 Old Western Road, Mason, OH 45040, USA.

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December 2012

Therapeutic potential of new second generation antipsychotics for major depressive disorder.

Expert Opin Investig Drugs 2010 Dec;19(12):1527-44

Lindner Center of HOPE, 4075 Old Western Row Road, Mason, Ohio 45040, USA.

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December 2010

Acamprosate in the treatment of binge eating disorder: a placebo-controlled trial.

Int J Eat Disord 2011 Jan;44(1):81-90

Lindner Center of HOPE, Research Institute, 4075 Old Western Row Road, Mason, OH45040, USA.

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January 2011

A randomized, placebo-controlled study of adjunctive ramelteon in ambulatory bipolar I disorder with manic symptoms and sleep disturbance.

Int Clin Psychopharmacol 2011 Jan;26(1):48-53

aLindner Center of HOPE, Mason, Ohio and University of Cincinnati College of Medicine, Cincinnati, Ohio bDepartment of Psychiatry & Health Behavior, Medical College of Georgia, Augusta, Georgia, USA.

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January 2011

Memantine efficacy and safety in patients with acute mania associated with bipolar I disorder: a pilot evaluation.

Clin Neuropharmacol 2009 Jul-Aug;32(4):199-204

Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.

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October 2009

Suggestive evidence for linkage of ADHD features in bipolar disorder to chromosome 10p14.

Am J Med Genet B Neuropsychiatr Genet 2010 Jan;153B(1):260-8

Department of Psychiatry, University of California, San Diego, La Jolla, California, USA.

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January 2010

Long-term safety and efficacy of ziprasidone in subpopulations of patients with bipolar mania.

J Clin Psychiatry 2009 Jun;70(6):844-51

Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0559, USA.

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June 2009

Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study.

J Clin Psychiatry 2009 Apr 7;70(4):450-7. Epub 2009 Apr 7.

Department of Psychiatry, Veterans Affairs Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, Los Angeles, CA, USA.

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April 2009

Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial.

Int Clin Psychopharmacol 2009 May;24(3):150-8

Department of Psychiatry, University of Cincinnati College of Medicine, Lindner Center of HOPE, Mason, Ohio 45040, USA.

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May 2009

Clinical and economic effects of unrecognized or inadequately treated bipolar disorder.

J Psychiatr Pract 2008 May;14 Suppl 2:31-8

University of Cincinnati College of Medicine, USA.

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May 2008

Characterizing impulsivity in mania.

Bipolar Disord 2009 Feb;11(1):41-51

Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA.

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February 2009

Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression.

Am J Psychiatry 2009 Feb 17;166(2):164-72. Epub 2008 Nov 17.

Department of Psychiatry, Mayo Mood Clinic and Research Program, Mayo Clinic, 200 First St., S.W., Rochester, MN 55901, USA.

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February 2009

Role of serotonin and dopamine receptor binding in antipsychotic efficacy.

Prog Brain Res 2008 ;172:155-75

Cincinnati Veterans Affairs Medical Center, 3200 Vine Street, ML0559, Cincinnati, OH 45220, USA.

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January 2009

Bipolar depression: best practices for the outpatient.

CNS Spectr 2007 Dec;12(12 Suppl 20):1-14

Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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December 2007

Atypical neuroleptic malignant syndrome: diagnostic controversies and considerations.

Pharmacotherapy 2008 Apr;28(4):530-5

Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA.

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April 2008

Preliminary evidence for gender-specific effects of topiramate as a potential aid to smoking cessation.

Addiction 2008 Apr;103(4):687-94

Tri-State Tobacco and Alcohol Research Center, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA.

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April 2008

Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial.

J Clin Psychiatry 2008 Mar;69(3):433-40

Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0559, USA.

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March 2008

Treatment costs and health care utilization for patients with bipolar disorder in a large managed care population.

Value Health 2008 May-Jun;11(3):416-23. Epub 2007 Dec 17.

College of Pharmacy, University of Cincinnati Medical Center, Cincinnati, OH, USA.

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June 2008

High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial.

Hum Psychopharmacol 2008 Jan;23(1):1-11

Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0559, USA.

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January 2008

Bipolar depression: best practices for the hospitalized patient.

CNS Spectr 2007 Nov;12(11 Suppl 19):1-13

Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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November 2007

Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo.

J Clin Psychiatry 2007 Oct;68(10):1480-91

Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0559, USA.

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October 2007

Emotional eating and emotional eating alternatives in subjects undergoing bariatric surgery.

Obes Surg 2007 Aug;17(8):1091-6

Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0559, USA.

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August 2007

Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorder.

J Affect Disord 2008 Apr 20;107(1-3):127-33. Epub 2007 Sep 20.

Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0559, USA.

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April 2008

A retrospective chart review of intramuscular ziprasidone for agitation in children and adolescents on psychiatric units: prospective studies are needed.

J Child Adolesc Psychopharmacol 2007 Aug;17(4):503-9

Children's Hospital Medical Center, Division of Child and Adolescent Psychiatry, Cincinnati, Ohio 45229-3039, USA.

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August 2007

Treatment costs related to bipolar disorder and comorbid conditions among Medicaid patients with bipolar disorder.

Psychiatr Serv 2007 Aug;58(8):1073-8

Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy and the Institute for the Study of Health, University of Cincinnati Academic Health Center, 3225 Eden Avenue, Cincinnati, OH 45267-0004, USA.

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August 2007

Neuroleptic malignant syndrome.

Am J Psychiatry 2007 Jun;164(6):870-6

University of Cincinnati, Department of Psychiatry, College of Medicine, Box 670559, Cincinnati, OH 45267-0559, USA.

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June 2007

The poor prognosis of childhood-onset bipolar disorder.

J Pediatr 2007 May;150(5):485-90

Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, MD 20892-1272, USA.

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May 2007

Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trial.

J Clin Psychiatry 2007 Mar;68(3):390-8

Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559, USA.

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March 2007

Psychiatric and metabolic characteristics of childhood versus adult-onset obesity in patients seeking weight management.

Eat Behav 2007 Apr 5;8(2):266-76. Epub 2006 Dec 5.

Psychopharmacology Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267-0559, USA.

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April 2007

Alcoholism and anxiety in bipolar illness: differential lifetime anxiety comorbidity in bipolar I women with and without alcoholism.

J Affect Disord 2007 Aug 23;101(1-3):211-7. Epub 2007 Jan 23.

Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.

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August 2007

Dopamine and serotonin receptor binding and antipsychotic efficacy.

Neuropsychopharmacology 2007 Aug 24;32(8):1715-26. Epub 2007 Jan 24.

Psychiatry Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH, USA.

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August 2007