Paul D Chastain

Paul D Chastain

UNVERIFIED PROFILE

Are you Paul D Chastain?   Register this Author

Register author
Paul D Chastain

Paul D Chastain

Publications by authors named "Paul D Chastain"

Are you Paul D Chastain?   Register this Author

28Publications

338Reads

25Profile Views

JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells.

Oncogene 2019 07 9;38(28):5643-5657. Epub 2019 Apr 9.

Department of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, 60612, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-019-0814-6DOI Listing
July 2019

Single molecule mtDNA fiber FISH for analyzing numtogenesis.

Anal Biochem 2018 07 18;552:45-49. Epub 2017 Mar 18.

Departments of Genetics, Pathology, Environmental Health, Center for Free Radical Biology, Center for Aging, UAB Comprehensive Cancer Center, University of Alabama at Birmingham, AL 35294, United States; Birmingham Veterans Affairs Medical Center, Birmingham, AL 35294, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ab.2017.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814351PMC
July 2018

DNA damage checkpoint responses in the S phase of synchronized diploid human fibroblasts.

Photochem Photobiol 2015 Jan-Feb;91(1):109-16. Epub 2014 Nov 24.

College of Osteopathic Medicine, William Carey University, Hattiesburg, MS.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/php.12361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303954PMC
January 2016

SWI/SNF complexes are required for full activation of the DNA-damage response.

Oncotarget 2015 Jan;6(2):732-45

Department of Genetics and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359251PMC
http://dx.doi.org/10.18632/oncotarget.2715DOI Listing
January 2015

DNA damage checkpoint responses in the S phase of synchronized diploid human fibroblasts.

Photochem Photobiol 2015 Jan-Feb;91(1):109-16. Epub 2014 Nov 24.

College of Osteopathic Medicine, William Carey University, Hattiesburg, MS.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/php.12361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303954PMC
January 2016

Titanium dioxide nanoparticles activate the ATM-Chk2 DNA damage response in human dermal fibroblasts.

Nanotoxicology 2013 Sep 23;7(6):1111-9. Epub 2012 Aug 23.

Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.

View Article

Download full-text PDF

Source
http://www.tandfonline.com/doi/full/10.3109/17435390.2012.71
Publisher Site
http://dx.doi.org/10.3109/17435390.2012.710659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867138PMC
September 2013

Human CST promotes telomere duplex replication and general replication restart after fork stalling.

EMBO J 2012 Aug 3;31(17):3537-49. Epub 2012 Aug 3.

Department of Cancer and Cell Biology, University of Cincinnati, Cincinnati, OH 45267, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emboj.2012.215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433780PMC
August 2012

Temporal and functional analysis of DNA replicated in early S phase.

Adv Enzyme Regul 2011 18;51(1):257-71. Epub 2010 Nov 18.

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.advenzreg.2010.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079056PMC
August 2011

BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.

Nucleic Acids Res 2010 Nov 22;38(20):6906-19. Epub 2010 Jun 22.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkq559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978342PMC
November 2010

Abasic sites preferentially form at regions undergoing DNA replication.

FASEB J 2010 Oct 28;24(10):3674-80. Epub 2010 May 28.

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7525, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.09-145276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996904PMC
October 2010

DNA replication and the GINS complex: localization on extended chromatin fibers.

Epigenetics Chromatin 2009 May 14;2(1). Epub 2009 May 14.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-8935-2-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686697PMC
May 2009

Analysis of re-replication from deregulated origin licensing by DNA fiber spreading.

Nucleic Acids Res 2009 Jan 14;37(1):60-9. Epub 2008 Nov 14.

Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7260, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkn912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615611PMC
January 2009

DNA replication in early S phase pauses near newly activated origins.

Cell Cycle 2008 May 29;7(10):1440-8. Epub 2008 Feb 29.

Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7525, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698818PMC
http://dx.doi.org/10.4161/cc.7.10.5879DOI Listing
May 2008

Early S phase DNA replication: a search for targets of carcinogenesis.

Adv Enzyme Regul 2007 28;47:127-38. Epub 2006 Dec 28.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599-7525, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.advenzreg.2006.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063577PMC
November 2007

Mapping of an origin of DNA replication in the promoter of fragile X gene FMR1.

Exp Mol Pathol 2007 Apr 28;82(2):190-6. Epub 2006 Dec 28.

Department of Pathology and Laboratory Medicine, C.B. #7525, University of North Carolina, Chapel Hill, NC 27599-7525, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexmp.2006.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934615PMC
April 2007

The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement.

Mol Cell Biol 2007 Apr 12;27(8):3131-42. Epub 2007 Feb 12.

Lineberger Comprehensive Cancer Center, CB 7295, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.02190-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899931PMC
April 2007

Architecture of the bacteriophage T4 replication complex revealed with nanoscale biopointers.

J Biol Chem 2007 Jan 13;282(2):1098-108. Epub 2006 Nov 13.

Laboratory of Molecular and Cellular Biology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892-0830, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M606772200
Publisher Site
http://dx.doi.org/10.1074/jbc.M606772200DOI Listing
January 2007

Nonrandom AP site distribution in highly proliferative cells.

FASEB J 2006 Dec 26;20(14):2612-4. Epub 2006 Oct 26.

Department of Pathology and Laboratory, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7525, USA.

View Article

Download full-text PDF

Source
http://www.fasebj.org/doi/10.1096/fj.06-6145fje
Publisher Site
http://dx.doi.org/10.1096/fj.06-6145fjeDOI Listing
December 2006

Checkpoint regulation of replication dynamics in UV-irradiated human cells.

Cell Cycle 2006 Sep 15;5(18):2160-7. Epub 2006 Sep 15.

Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7525 USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.5.18.3236DOI Listing
September 2006

A late origin of DNA replication in the trinucleotide repeat region of the human FMR2 gene.

Cell Cycle 2006 Apr 17;5(8):869-72. Epub 2006 Apr 17.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7525, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.5.8.2648DOI Listing
April 2006

Mapping subunit location on the Saccharomyces cerevisiae origin recognition complex free and bound to DNA using a novel nanoscale biopointer.

J Biol Chem 2004 Aug 16;279(35):36354-62. Epub 2004 Jun 16.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599-7295, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M403501200DOI Listing
August 2004

Architecture of the replication complex and DNA loops at the fork generated by the bacteriophage t4 proteins.

J Biol Chem 2003 Jun 20;278(23):21276-85. Epub 2003 Mar 20.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M301573200
Publisher Site
http://dx.doi.org/10.1074/jbc.M301573200DOI Listing
June 2003

Sticky DNA, a long GAA.GAA.TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene.

J Biol Chem 2002 Oct 2;277(42):39217-27. Epub 2002 Aug 2.

Center for Genome Research, Institute of Biosciences and Technology, Texas A&M University, Texas Medical Center, Houston, Texas 77030-3303, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M205209200DOI Listing
October 2002

Lagging strand synthesis in coordinated DNA synthesis by bacteriophage t7 replication proteins.

J Mol Biol 2002 Feb;316(1):19-34

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1006/jmbi.2001.5325DOI Listing
February 2002