Paul C Boutros

Paul C Boutros

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Paul C Boutros

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A controlled trial of HNSCC patient-derived xenografts reveals broad efficacy of PI3Kα inhibition in controlling tumor growth.

Int J Cancer 2019 Oct 18;145(8):2100-2106. Epub 2018 Dec 18.

Department of Otolaryngology - Head and Neck Surgery, Western University, London, Canada.

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http://dx.doi.org/10.1002/ijc.32009DOI Listing
October 2019

MicroRNA‑198 suppresses prostate tumorigenesis by targeting MIB1.

Oncol Rep 2019 Sep 15;42(3):1047-1056. Epub 2019 Jul 15.

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.3892/or.2019.7234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667842PMC
September 2019

Rethinking Lupus Nephritis Classification on a Molecular Level.

J Clin Med 2019 Sep 23;8(10). Epub 2019 Sep 23.

Division of Nephrology, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, ON M5G 2C4, Canada.

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http://dx.doi.org/10.3390/jcm8101524DOI Listing
September 2019

2,3,7,8-Tetrachlorodibenzo-p-dioxin modifies alternative splicing in mouse liver.

PLoS One 2019 6;14(8):e0219747. Epub 2019 Aug 6.

Cell Biology Department, Center for Research and Advanced Studies of the National Polytechnic Institute, CINVESTAN-IPN, Mexico City, Mexico.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219747PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684058PMC
August 2019

Molecular Hallmarks of Multiparametric Magnetic Resonance Imaging Visibility in Prostate Cancer.

Eur Urol 2019 Jul 24;76(1):18-23. Epub 2019 Jan 24.

Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Institute of Urologic Oncology, University of California, Los Angeles, CA, USA; Department of Urology, David Geffen School of Medicine, 300 Stein Plaza, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.12.036DOI Listing
July 2019

Landscape of transcriptomic interactions between breast cancer and its microenvironment.

Nat Commun 2019 07 15;10(1):3116. Epub 2019 Jul 15.

Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada.

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http://dx.doi.org/10.1038/s41467-019-10929-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629667PMC
July 2019

Modelling the MYC-driven normal-to-tumour switch in breast cancer.

Dis Model Mech 2019 Jul 26;12(7). Epub 2019 Jul 26.

Princess Margaret Cancer Centre, University Health Network, 101 College St, Toronto, ON M5G 0A3, Canada

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http://dx.doi.org/10.1242/dmm.038083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679384PMC
July 2019

The influence of BRCA2 mutation on localized prostate cancer.

Nat Rev Urol 2019 May;16(5):281-290

Monash Partners Comprehensive Cancer Consortium and Cancer Program, Biomedicine Discovery Institute, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology and Department of Physiology, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/s41585-019-0164-8DOI Listing
May 2019

What Is Oligometastatic Prostate Cancer?

Eur Urol Focus 2019 03 12;5(2):159-161. Epub 2019 Jan 12.

Department of Human Genetics, University of California, Los Angeles, CA, USA; Department of Urology, University of California, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA; Institute for Precision Health, University of California, Los Angeles, CA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24054569183041
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http://dx.doi.org/10.1016/j.euf.2018.12.009DOI Listing
March 2019

The Proteogenomic Landscape of Curable Prostate Cancer.

Cancer Cell 2019 Mar;35(3):414-427.e6

Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Human Genetics, University of California, 12-109 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, CA 90024, USA; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA 90024, USA; Institute for Precision Health, University of California, Los Angeles, CA 90024, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511374PMC
March 2019

Transcriptomic Impact of IMA-08401, a Novel AHR Agonist Resembling Laquinimod, on Rat Liver.

Int J Mol Sci 2019 Mar 19;20(6). Epub 2019 Mar 19.

Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.

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http://dx.doi.org/10.3390/ijms20061370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471016PMC
March 2019

Genomic Classifier for Guiding Treatment of Intermediate-Risk Prostate Cancers to Dose-Escalated Image Guided Radiation Therapy Without Hormone Therapy.

Int J Radiat Oncol Biol Phys 2019 01 29;103(1):84-91. Epub 2018 Aug 29.

Princess Margaret Cancer Centre, University Health Network, Ontario, Canada; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore; Division of Medical Sciences, National Cancer Centre Singapore, Singapore; Oncology Academic Program, Duke-NUS Medical School, Singapore.

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http://dx.doi.org/10.1016/j.ijrobp.2018.08.030DOI Listing
January 2019

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

Mol Cell 2018 12 8;72(5):836-848.e7. Epub 2018 Nov 8.

Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.09.031DOI Listing
December 2018

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Cancer Cell 2018 12;34(6):996-1011.e8

Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.10.016DOI Listing
December 2018

The Promise and Perils of Sequencing Individual Prostate Cancer Nuclei.

Authors:
Paul C Boutros

Eur Urol 2018 11 31;74(5):560-561. Epub 2018 Jul 31.

Ontario Institute for Cancer Research, Toronto, Canada; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183055
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http://dx.doi.org/10.1016/j.eururo.2018.07.028DOI Listing
November 2018

Sex Differences in Cancer Driver Genes and Biomarkers.

Cancer Res 2018 10;78(19):5527-5537

Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-0362DOI Listing
October 2018

MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis.

Cancer Cell 2018 10;34(4):579-595.e8

Princess Margaret Cancer Centre, Toronto, ON M5G1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G1L7, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108183041
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http://dx.doi.org/10.1016/j.ccell.2018.09.001DOI Listing
October 2018

miRNA-106a and prostate cancer radioresistance: a novel role for LITAF in ATM regulation.

Mol Oncol 2018 08 14;12(8):1324-1341. Epub 2018 Jun 14.

Biological Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.1002/1878-0261.12328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068351PMC
August 2018

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.

Cell 2018 07 19;174(3):564-575.e18. Epub 2018 Jul 19.

Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.014DOI Listing
July 2018

Mutations in Mitochondrial DNA From Pancreatic Ductal Adenocarcinomas Associate With Survival Times of Patients and Accumulate as Tumors Progress.

Gastroenterology 2018 05 29;154(6):1620-1624.e5. Epub 2018 Mar 29.

Informatics Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.01.029DOI Listing
May 2018

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Nat Genet 2018 05 16;50(5):682-692. Epub 2018 Apr 16.

The Institute of Cancer Research, London, UK.

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http://www.nature.com/articles/s41588-018-0086-z
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http://dx.doi.org/10.1038/s41588-018-0086-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372064PMC
May 2018

The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression.

Cell 2018 05 19;173(4):1003-1013.e15. Epub 2018 Apr 19.

Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.029DOI Listing
May 2018

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.

EBioMedicine 2018 May 23;31:182-189. Epub 2018 Apr 23.

Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester M20 4BX, UK; NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014579PMC
May 2018

A Partner in Crime: Tumor-associated Stroma and Metastatic Prostate Cancer.

Eur Urol 2018 04 22;73(4):533-534. Epub 2017 Dec 22.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.11.029DOI Listing
April 2018

Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer.

J Ovarian Res 2018 Apr 4;11(1):27. Epub 2018 Apr 4.

Diagnostic Development, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.

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http://dx.doi.org/10.1186/s13048-018-0399-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885411PMC
April 2018

NanoStringNormCNV: pre-processing of NanoString CNV data.

Bioinformatics 2018 03;34(6):1034-1036

Informatics and Biocomputing Program, Ontario Institute for Cancer Research.

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http://dx.doi.org/10.1093/bioinformatics/btx707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860631PMC
March 2018

Germline contamination and leakage in whole genome somatic single nucleotide variant detection.

BMC Bioinformatics 2018 01 31;19(1):28. Epub 2018 Jan 31.

Informatics & Biocomputing Program, Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-018-2046-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793408PMC
January 2018

Pro- and anti-inflammatory cytokine associations with major depression in cancer patients.

Psychooncology 2017 Dec 6;26(12):2149-2156. Epub 2016 Dec 6.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pon.4316DOI Listing
December 2017

Response.

J Natl Cancer Inst 2017 12;109(12)

Lunenfeld-Tanenbaum Research Institute and Department of Surgery, Division of Urology, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/jnci/djx122DOI Listing
December 2017

Cytokines and depression in cancer patients and caregivers.

Neuropsychiatr Dis Treat 2017 28;13:2903-2911. Epub 2017 Nov 28.

Princess Margaret Cancer Centre, Department of Supportive Care, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2147/NDT.S144774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713706PMC
November 2017

Comparison of pre-processing methods for Infinium HumanMethylation450 BeadChip array.

Bioinformatics 2017 Oct;33(20):3151-3157

Informatics, Ontario Institute for Cancer Research.

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http://dx.doi.org/10.1093/bioinformatics/btx372DOI Listing
October 2017

TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer.

Nat Genet 2017 Sep 7;49(9):1336-1345. Epub 2017 Aug 7.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ng.3930DOI Listing
September 2017

Translating a Prognostic DNA Genomic Classifier into the Clinic: Retrospective Validation in 563 Localized Prostate Tumors.

Eur Urol 2017 07 1;72(1):22-31. Epub 2016 Nov 1.

Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.10.013DOI Listing
July 2017

Kronos: a workflow assembler for genome analytics and informatics.

Gigascience 2017 07;6(7):1-10

Department of Molecular Oncology, British Columbia Cancer Agency, 675 West 10th Ave, V5Z 1L3 Vancouver, BC, Canada.

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http://dx.doi.org/10.1093/gigascience/gix042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569921PMC
July 2017

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Med 2017 07 18;9(1):62. Epub 2017 Jul 18.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1186/s13073-017-0454-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514513PMC
July 2017

The Immune Microenvironment, Genome-wide Copy Number Aberrations, and Survival in Mesothelioma.

J Thorac Oncol 2017 05 28;12(5):850-859. Epub 2017 Feb 28.

Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; Department of Medical Oncology, Austin Health, Olivia-Newton John Cancer and Wellness Centre, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2017.02.013DOI Listing
May 2017

2,3,7,8 Tetrachlorodibenzo-p-dioxin-induced RNA abundance changes identify Ackr3, Col18a1, Cyb5a and Glud1 as candidate mediators of toxicity.

Arch Toxicol 2017 Jan 30;91(1):325-338. Epub 2016 Apr 30.

Informatics and Bio-computing Program, MaRS Centre, Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.

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http://dx.doi.org/10.1007/s00204-016-1720-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225275PMC
January 2017

Nanocall: an open source basecaller for Oxford Nanopore sequencing data.

Bioinformatics 2017 01 10;33(1):49-55. Epub 2016 Sep 10.

Ontario Institute for Cancer Research, Toronto M5G 0A3, Canada.

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http://dx.doi.org/10.1093/bioinformatics/btw569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408768PMC
January 2017

Erratum to: A bedr way of genomic interval processing.

Source Code Biol Med 2017 9;12. Epub 2017 Jan 9.

Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, M5G 0A3 Canada.

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http://dx.doi.org/10.1186/s13029-016-0061-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223540PMC
January 2017

A bedr way of genomic interval processing.

Source Code Biol Med 2016 15;11:14. Epub 2016 Dec 15.

Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, M5G 0A3 Canada.

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http://dx.doi.org/10.1186/s13029-016-0059-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157088PMC
December 2016

VennDiagramWeb: a web application for the generation of highly customizable Venn and Euler diagrams.

BMC Bioinformatics 2016 Oct 3;17(1):401. Epub 2016 Oct 3.

Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048655PMC
http://dx.doi.org/10.1186/s12859-016-1281-5DOI Listing
October 2016

The parameter sensitivity of random forests.

BMC Bioinformatics 2016 Sep 1;17(1):331. Epub 2016 Sep 1.

Informatics and Bio-computing Program, Ontario Institute for Cancer Research, Toronto, Canada.

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http://dx.doi.org/10.1186/s12859-016-1228-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009551PMC
September 2016

Current and Evolving Methods to Visualize Biological Data in Cancer Research.

J Natl Cancer Inst 2016 08 31;108(8). Epub 2016 May 31.

Department of Medical Oncology and Olivia-Newton John Cancer Research Institute, Austin Health, Melbourne, Australia (PLC, TJ); School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia (CG); Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Canada (PCB); Department of Medical Biophysics and Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada (PCB); Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada (PWP).

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http://dx.doi.org/10.1093/jnci/djw031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017943PMC
August 2016

Comparing continuous and discrete analyses of breast cancer survival information.

Genomics 2016 08 14;108(2):78-83. Epub 2016 Jun 14.

Informatics and Bio-computing Program, Ontario Institute for Cancer Research, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Canada; Department of Pharmacology, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2016.06.002DOI Listing
August 2016

BAMQL: a query language for extracting reads from BAM files.

BMC Bioinformatics 2016 Aug 11;17:305. Epub 2016 Aug 11.

Ontario Institute for Cancer Research, Suite 510, 661 University Avenue, M5G 0A3, Toronto, Canada.

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http://dx.doi.org/10.1186/s12859-016-1162-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982315PMC
August 2016

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.

Authors:
Genevera I Allen Nicola Amoroso Catalina Anghel Venkat Balagurusamy Christopher J Bare Derek Beaton Roberto Bellotti David A Bennett Kevin L Boehme Paul C Boutros Laura Caberlotto Cristian Caloian Frederick Campbell Elias Chaibub Neto Yu-Chuan Chang Beibei Chen Chien-Yu Chen Ting-Ying Chien Tim Clark Sudeshna Das Christos Davatzikos Jieyao Deng Donna Dillenberger Richard J B Dobson Qilin Dong Jimit Doshi Denise Duma Rosangela Errico Guray Erus Evan Everett David W Fardo Stephen H Friend Holger Fröhlich Jessica Gan Peter St George-Hyslop Satrajit S Ghosh Enrico Glaab Robert C Green Yuanfang Guan Ming-Yi Hong Chao Huang Jinseub Hwang Joseph Ibrahim Paolo Inglese Anandhi Iyappan Qijia Jiang Yuriko Katsumata John S K Kauwe Arno Klein Dehan Kong Roland Krause Emilie Lalonde Mario Lauria Eunjee Lee Xihui Lin Zhandong Liu Julie Livingstone Benjamin A Logsdon Simon Lovestone Tsung-Wei Ma Ashutosh Malhotra Lara M Mangravite Taylor J Maxwell Emily Merrill John Nagorski Aishwarya Namasivayam Manjari Narayan Mufassra Naz Stephen J Newhouse Thea C Norman Ramil N Nurtdinov Yen-Jen Oyang Yudi Pawitan Shengwen Peng Mette A Peters Stephen R Piccolo Paurush Praveen Corrado Priami Veronica Y Sabelnykova Philipp Senger Xia Shen Andrew Simmons Aristeidis Sotiras Gustavo Stolovitzky Sabina Tangaro Andrea Tateo Yi-An Tung Nicholas J Tustison Erdem Varol George Vradenburg Michael W Weiner Guanghua Xiao Lei Xie Yang Xie Jia Xu Hojin Yang Xiaowei Zhan Yunyun Zhou Fan Zhu Hongtu Zhu Shanfeng Zhu

Alzheimers Dement 2016 06 11;12(6):645-53. Epub 2016 Apr 11.

School of Computer Science, Fudan University, Shanghai, Shanghai, China; Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, Shanghai, China; Centre for Computational Systems Biology, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.jalz.2016.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474755PMC
June 2016

A genome-wide association study of non-HPV-related head and neck squamous cell carcinoma identifies prognostic genetic sequence variants in the MAP-kinase and hormone pathways.

Cancer Epidemiol 2016 06 9;42:173-80. Epub 2016 May 9.

Ontario Cancer Institute and Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada,; Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2016.05.001DOI Listing
June 2016

Log::ProgramInfo: A Perl module to collect and log data for bioinformatics pipelines.

Source Code Biol Med 2016 24;11. Epub 2016 Jun 24.

Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Suite 510, MaRS Centre, 661 University Ave, Toronto, Ontario Canada.

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http://dx.doi.org/10.1186/s13029-016-0055-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919834PMC
June 2016

Clonality of localized and metastatic prostate cancer.

Curr Opin Urol 2016 May;26(3):219-24

aDepartment of Medical Biophysics, University of Toronto bInformatics and Biocomputing Program, Ontario Institute for Cancer Research cDepartment of Pharmacology and Toxicology, University of Toronto dPrincess Margaret Cancer Centre, University Health Network eDepartment of Pathology, Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MOU.0000000000000279DOI Listing
May 2016

Allele-Skewed DNA Modification in the Brain: Relevance to a Schizophrenia GWAS.

Am J Hum Genet 2016 May 14;98(5):956-962. Epub 2016 Apr 14.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada; Institute of Medical Science, University of Toronto, ON M5S 1A8, Canada; Department of Psychiatry, University of Toronto, Toronto, ON M5T 1R8, Canada; Department of Pharmacology & Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863558PMC
May 2016