Publications by authors named "Paul C Boutros"

100Publications

Computational approaches to support comparative analysis of multiparametric tests: Modelling versus Training.

PLoS One 2020 3;15(9):e0238593. Epub 2020 Sep 3.

UCL (University College London) and National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0238593PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470374PMC
September 2020

Sex differences in oncogenic mutational processes.

Nat Commun 2020 08 28;11(1):4330. Epub 2020 Aug 28.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-020-17359-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455744PMC
August 2020

Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics.

Cell Syst 2020 Aug 24;11(2):186-195.e9. Epub 2020 Jul 24.

Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Faculty of Medicine, 52074 Aachen, Germany; European Molecular Biology Laboratory-The European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK; Institute for Computational Biomedicine, Heidelberg University Hospital and Heidelberg University, Faculty of Medicine, Bioquant Heidelberg, Hedelberg 69120, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cels.2020.06.013DOI Listing
August 2020

Determining the Impact of Spatial Heterogeneity on Genomic Prognostic Biomarkers for Localized Prostate Cancer.

Eur Urol Oncol 2020 Jun 27. Epub 2020 Jun 27.

Radiation Medicine Program, Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Techna Institute, University Health Network, Toronto, ON, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.euo.2020.06.005DOI Listing
June 2020

Urinary biomarkers in prostate cancer: to the miRnome and beyond.

Transl Androl Urol 2020 Apr;9(2):843-845

Department of Medical Biophysics, University of Toronto, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/tau.2019.11.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214960PMC
April 2020

Transgenerational epigenetic and transcriptomic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in rat.

Arch Toxicol 2020 05 10;94(5):1613-1624. Epub 2020 Apr 10.

Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 66, 00014, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00204-020-02730-5DOI Listing
May 2020

Transcriptomics in RCC.

Urol Oncol 2020 Oct 25;38(10):742-754. Epub 2020 Mar 25.

Institute of Urologic Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urolonc.2019.12.003DOI Listing
October 2020

Sex disparities in head & neck cancer driver genes: An analysis of the TCGA dataset.

Oral Oncol 2020 05 5;104:104614. Epub 2020 Mar 5.

Department of Otolaryngology - Head and Neck Surgery, University of Western Ontario, London, Ontario, Canada; Department of Oncology, University of Western Ontario, London, Ontario, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2020.104614DOI Listing
May 2020

Integrative pathway enrichment analysis of multivariate omics data.

Nat Commun 2020 02 5;11(1):735. Epub 2020 Feb 5.

Computational Biology Program, Ontario Institute for Cancer Research, 661 University Ave Suite 510, Toronto, ON, M5G 0A3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-13983-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002665PMC
February 2020

Divergent mutational processes distinguish hypoxic and normoxic tumours.

Nat Commun 2020 02 5;11(1):737. Epub 2020 Feb 5.

Department of Medical Biophysics, University of Toronto, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-14052-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002770PMC
February 2020

Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks.

Mol Cell 2020 03 17;77(6):1307-1321.e10. Epub 2020 Jan 17.

Computational Biology Program, Ontario Institute for Cancer Research, 661 University Avenue Suite 510, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON M5G 1L7, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2019.12.027DOI Listing
March 2020

Optimization and expansion of non-negative matrix factorization.

BMC Bioinformatics 2020 Jan 6;21(1). Epub 2020 Jan 6.

Informatics & Biocomputing, Ontario Institute for Cancer Research, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-019-3312-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945623PMC
January 2020

miR-191 promotes radiation resistance of prostate cancer through interaction with RXRA.

Cancer Lett 2020 03 23;473:107-117. Epub 2019 Dec 23.

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Canada; Department of Radiation Oncology, University of Toronto, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2019.12.025DOI Listing
March 2020

Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer.

Oral Oncol 2020 02 19;101:104529. Epub 2019 Dec 19.

Department of Otolaryngology, London Health Sciences Centre, London, Ontario, Canada; Department of Oncology, London Health Sciences Centre, London, Ontario, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2019.104529DOI Listing
February 2020

Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors.

Cancer Cell 2019 12 14;36(6):674-689.e6. Epub 2019 Nov 14.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2019.10.005DOI Listing
December 2019

Rethinking Lupus Nephritis Classification on a Molecular Level.

J Clin Med 2019 Sep 23;8(10). Epub 2019 Sep 23.

Division of Nephrology, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, ON M5G 2C4, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm8101524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832959PMC
September 2019

2,3,7,8-Tetrachlorodibenzo-p-dioxin modifies alternative splicing in mouse liver.

PLoS One 2019 6;14(8):e0219747. Epub 2019 Aug 6.

Cell Biology Department, Center for Research and Advanced Studies of the National Polytechnic Institute, CINVESTAN-IPN, Mexico City, Mexico.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219747PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684058PMC
March 2020

Modelling the MYC-driven normal-to-tumour switch in breast cancer.

Dis Model Mech 2019 07 26;12(7). Epub 2019 Jul 26.

Princess Margaret Cancer Centre, University Health Network, 101 College St, Toronto, ON M5G 0A3, Canada

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dmm.038083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679384PMC
July 2019

MicroRNA‑198 suppresses prostate tumorigenesis by targeting MIB1.

Oncol Rep 2019 Sep 15;42(3):1047-1056. Epub 2019 Jul 15.

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/or.2019.7234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667842PMC
September 2019

Landscape of transcriptomic interactions between breast cancer and its microenvironment.

Nat Commun 2019 07 15;10(1):3116. Epub 2019 Jul 15.

Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-10929-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629667PMC
July 2019

Transcriptomic Impact of IMA-08401, a Novel AHR Agonist Resembling Laquinimod, on Rat Liver.

Int J Mol Sci 2019 Mar 19;20(6). Epub 2019 Mar 19.

Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20061370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471016PMC
March 2019

The Proteogenomic Landscape of Curable Prostate Cancer.

Cancer Cell 2019 03;35(3):414-427.e6

Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Human Genetics, University of California, 12-109 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, CA 90024, USA; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA 90024, USA; Institute for Precision Health, University of California, Los Angeles, CA 90024, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511374PMC
March 2019

The influence of BRCA2 mutation on localized prostate cancer.

Nat Rev Urol 2019 05;16(5):281-290

Monash Partners Comprehensive Cancer Consortium and Cancer Program, Biomedicine Discovery Institute, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology and Department of Physiology, Monash University, Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41585-019-0164-8DOI Listing
May 2019

Molecular Hallmarks of Multiparametric Magnetic Resonance Imaging Visibility in Prostate Cancer.

Eur Urol 2019 07 24;76(1):18-23. Epub 2019 Jan 24.

Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Institute of Urologic Oncology, University of California, Los Angeles, CA, USA; Department of Urology, David Geffen School of Medicine, 300 Stein Plaza, Los Angeles, CA 90095, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2018.12.036DOI Listing
July 2019

What Is Oligometastatic Prostate Cancer?

Eur Urol Focus 2019 03 12;5(2):159-161. Epub 2019 Jan 12.

Department of Human Genetics, University of California, Los Angeles, CA, USA; Department of Urology, University of California, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA; Institute for Precision Health, University of California, Los Angeles, CA, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S24054569183041
Publisher Site
http://dx.doi.org/10.1016/j.euf.2018.12.009DOI Listing
March 2019

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Cancer Cell 2018 12;34(6):996-1011.e8

Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444093PMC
December 2018

A controlled trial of HNSCC patient-derived xenografts reveals broad efficacy of PI3Kα inhibition in controlling tumor growth.

Int J Cancer 2019 10 18;145(8):2100-2106. Epub 2018 Dec 18.

Department of Otolaryngology - Head and Neck Surgery, Western University, London, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.32009DOI Listing
October 2019

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

Mol Cell 2018 12 8;72(5):836-848.e7. Epub 2018 Nov 8.

Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2018.09.031DOI Listing
December 2018

MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis.

Cancer Cell 2018 10;34(4):579-595.e8

Princess Margaret Cancer Centre, Toronto, ON M5G1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G1L7, Canada. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15356108183041
Publisher Site
http://dx.doi.org/10.1016/j.ccell.2018.09.001DOI Listing
October 2018

Sex Differences in Cancer Driver Genes and Biomarkers.

Cancer Res 2018 10;78(19):5527-5537

Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-18-0362DOI Listing
October 2018

Genomic Classifier for Guiding Treatment of Intermediate-Risk Prostate Cancers to Dose-Escalated Image Guided Radiation Therapy Without Hormone Therapy.

Int J Radiat Oncol Biol Phys 2019 01 29;103(1):84-91. Epub 2018 Aug 29.

Princess Margaret Cancer Centre, University Health Network, Ontario, Canada; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore; Division of Medical Sciences, National Cancer Centre Singapore, Singapore; Oncology Academic Program, Duke-NUS Medical School, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2018.08.030DOI Listing
January 2019

The Promise and Perils of Sequencing Individual Prostate Cancer Nuclei.

Authors:
Paul C Boutros

Eur Urol 2018 11 31;74(5):560-561. Epub 2018 Jul 31.

Ontario Institute for Cancer Research, Toronto, Canada; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Canada. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03022838183055
Publisher Site
http://dx.doi.org/10.1016/j.eururo.2018.07.028DOI Listing
November 2018

Response.

J Natl Cancer Inst 2017 12;109(12)

Lunenfeld-Tanenbaum Research Institute and Department of Surgery, Division of Urology, Mount Sinai Hospital, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djx122DOI Listing
December 2017

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.

Cell 2018 07 19;174(3):564-575.e18. Epub 2018 Jul 19.

Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.06.014DOI Listing
July 2018

miRNA-106a and prostate cancer radioresistance: a novel role for LITAF in ATM regulation.

Mol Oncol 2018 08 14;12(8):1324-1341. Epub 2018 Jun 14.

Biological Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/1878-0261.12328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068351PMC
August 2018

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.

EBioMedicine 2018 May 23;31:182-189. Epub 2018 Apr 23.

Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester M20 4BX, UK; NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2018.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014579PMC
May 2018

The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression.

Cell 2018 05 19;173(4):1003-1013.e15. Epub 2018 Apr 19.

Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.03.029DOI Listing
May 2018

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Nat Genet 2018 05 16;50(5):682-692. Epub 2018 Apr 16.

The Institute of Cancer Research, London, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41588-018-0086-z
Publisher Site
http://dx.doi.org/10.1038/s41588-018-0086-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372064PMC
May 2018

Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer.

J Ovarian Res 2018 Apr 4;11(1):27. Epub 2018 Apr 4.

Diagnostic Development, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13048-018-0399-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885411PMC
April 2018

Germline contamination and leakage in whole genome somatic single nucleotide variant detection.

BMC Bioinformatics 2018 01 31;19(1):28. Epub 2018 Jan 31.

Informatics & Biocomputing Program, Ontario Institute for Cancer Research, 661 University Avenue, Suite 510, Toronto, Ontario, M5G 0A3, Canada.

View Article

Download full-text PDF

Source
https://bmcbioinformatics.biomedcentral.com/articles/10.1186
Publisher Site
http://dx.doi.org/10.1186/s12859-018-2046-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793408PMC
January 2018

Mutations in Mitochondrial DNA From Pancreatic Ductal Adenocarcinomas Associate With Survival Times of Patients and Accumulate as Tumors Progress.

Gastroenterology 2018 05 29;154(6):1620-1624.e5. Epub 2018 Mar 29.

Informatics Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2018.01.029DOI Listing
May 2018

A Partner in Crime: Tumor-associated Stroma and Metastatic Prostate Cancer.

Eur Urol 2018 04 22;73(4):533-534. Epub 2017 Dec 22.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2017.11.029DOI Listing
April 2018

Cytokines and depression in cancer patients and caregivers.

Neuropsychiatr Dis Treat 2017 28;13:2903-2911. Epub 2017 Nov 28.

Princess Margaret Cancer Centre, Department of Supportive Care, University Health Network, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/NDT.S144774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713706PMC
November 2017

NanoStringNormCNV: pre-processing of NanoString CNV data.

Bioinformatics 2018 03;34(6):1034-1036

Informatics and Biocomputing Program, Ontario Institute for Cancer Research.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btx707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860631PMC
March 2018

TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer.

Nat Genet 2017 Sep 7;49(9):1336-1345. Epub 2017 Aug 7.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3930DOI Listing
September 2017

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Med 2017 07 18;9(1):62. Epub 2017 Jul 18.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13073-017-0454-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514513PMC
July 2017

Kronos: a workflow assembler for genome analytics and informatics.

Gigascience 2017 07;6(7):1-10

Department of Molecular Oncology, British Columbia Cancer Agency, 675 West 10th Ave, V5Z 1L3 Vancouver, BC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gigascience/gix042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569921PMC
July 2017

Comparison of pre-processing methods for Infinium HumanMethylation450 BeadChip array.

Bioinformatics 2017 Oct;33(20):3151-3157

Informatics, Ontario Institute for Cancer Research.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btx372DOI Listing
October 2017

The Immune Microenvironment, Genome-wide Copy Number Aberrations, and Survival in Mesothelioma.

J Thorac Oncol 2017 05 28;12(5):850-859. Epub 2017 Feb 28.

Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; Department of Medical Oncology, Austin Health, Olivia-Newton John Cancer and Wellness Centre, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2017.02.013DOI Listing
May 2017