Paul Brennan

Paul Brennan

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Paul Brennan

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Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.

Nat Commun 2020 Jul 3;11(1):3353. Epub 2020 Jul 3.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.

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http://dx.doi.org/10.1038/s41467-020-16483-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335068PMC
July 2020

Genome-wide association study data reveal genetic susceptibility to chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma risk.

Cancer Res 2020 Jul 8. Epub 2020 Jul 8.

Division of Cancer Epidemiology and Genetics, National Cancer Institute

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http://dx.doi.org/10.1158/0008-5472.CAN-20-0447DOI Listing
July 2020

Drains result in greater reduction of subdural width and midline shift in burr hole evacuation of chronic subdural haematoma.

Acta Neurochir (Wien) 2020 Jun 27;162(6):1455-1466. Epub 2020 Apr 27.

Translational Neurosurgery, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1007/s00701-020-04356-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235065PMC
June 2020

Stratifying Brain Tumour Histological Sub-Types: The Application of ATR-FTIR Serum Spectroscopy in Secondary Care.

Cancers (Basel) 2020 Jun 27;12(7). Epub 2020 Jun 27.

WestCHEM, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George St, Glasgow G1 1RD, UK.

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http://dx.doi.org/10.3390/cancers12071710DOI Listing
June 2020

Hpv impact on oropharyngeal cancer patients treated at the largest cancer center from Brazil.

Cancer Lett 2020 May 19;477:70-75. Epub 2020 Feb 19.

Molecular Carcinogenesis Program, Brazilian National Cancer Institute. Rua André Cavalcanti, 37, Centro, 20231-050, Rio de Janeiro, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2020.02.023DOI Listing
May 2020

Biofluid diagnostics by FTIR spectroscopy: A platform technology for cancer detection.

Cancer Lett 2020 May 26;477:122-130. Epub 2020 Feb 26.

WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre, 99 George Street, Glasgow, G1 1RD, UK; ClinSpec Diagnostics Ltd., Technology and Innovation Centre, 99 George Street, Glasgow, G1 1RD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2020.02.020DOI Listing
May 2020

Opium use and subsequent incidence of cancer: results from the Golestan Cohort Study.

Lancet Glob Health 2020 May;8(5):e649-e660

Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(20)30059-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196888PMC
May 2020

Protein-altering germline mutations implicate novel genes related to lung cancer development.

Authors:
Xuemei Ji Semanti Mukherjee Maria Teresa Landi Yohan Bosse Philippe Joubert Dakai Zhu Ivan Gorlov Xiangjun Xiao Younghun Han Olga Gorlova Rayjean J Hung Yonathan Brhane Robert Carreras-Torres David C Christiani Neil Caporaso Mattias Johansson Geoffrey Liu Stig E Bojesen Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert Chu Chen Jinyoung Byun Konstantin H Dragnev John K Field Lambertus Fa Kiemeney Philip Lazarus Shan Zienolddiny Stephen Lam Matthew B Schabath Angeline S Andrew Pier A Bertazzi Angela C Pesatori Nancy Diao Li Su Lei Song Ruyang Zhang Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher Haiman Lynne Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Erik H F M van der Heijden Jin Hee Kim Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Gary E Goodman Angela Cox Fiona Taylor Penella Woll Erich Wichmann Thomas Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Lesley M Butler Kenneth Offit Preethi Srinivasan Chaitanya Bandlamudi Matthew D Hellmann David B Solit Mark E Robson Charles M Rudin Zsofia K Stadler Barry S Taylor Michael F Berger Richard Houlston John McLaughlin Victoria Stevens David C Nickle Ma'en Obeidat Wim Timens María Soler Artigas Sanjay Shete Hermann Brenner Stephen Chanock Paul Brennan James D McKay Christopher I Amos

Nat Commun 2020 May 11;11(1):2220. Epub 2020 May 11.

The Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41467-020-15905-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214407PMC
May 2020

Evaluation of pathologic staging using number of nodes in p16-negative head and neck cancer.

Oral Oncol 2020 May 31;108:104800. Epub 2020 May 31.

Department of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2020.104800DOI Listing
May 2020

Targeting the Small GTPase Superfamily through Their Regulatory Proteins.

Angew Chem Int Ed Engl 2020 Apr 30;59(16):6342-6366. Epub 2020 Jan 30.

Structural Genomics Consortium, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ, UK.

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http://dx.doi.org/10.1002/anie.201900585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204875PMC
April 2020

Determining the role for uric acid in non-alcoholic steatohepatitis development and the utility of urate metabolites in diagnosis: An opinion review.

World J Gastroenterol 2020 Apr;26(15):1683-1690

Department of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom.

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http://dx.doi.org/10.3748/wjg.v26.i15.1683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183862PMC
April 2020

Effective Gene Modification in Mouse Tissue-Resident Peritoneal Macrophages by Intraperitoneal Delivery of Lentiviral Vectors.

Mol Ther Methods Clin Dev 2020 Mar 18;16:21-31. Epub 2019 Oct 18.

Systems Immunity Research Institute, Cardiff University School of Medicine, Tenovus Building, Heath Park, Cardiff CF14 4XN, UK.

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http://dx.doi.org/10.1016/j.omtm.2019.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838965PMC
March 2020

Anaesthesia workload implications of a 24/7 national stroke thrombectomy service.

Br J Anaesth 2020 03 18;124(3):e33-e34. Epub 2019 Dec 18.

Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.bja.2019.11.024DOI Listing
March 2020

Assessment of Biomarker Testing for Lung Cancer Screening Eligibility.

JAMA Netw Open 2020 Mar 2;3(3):e200409. Epub 2020 Mar 2.

Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.0409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059020PMC
March 2020

The association between diet quality and cancer incidence of the head and neck.

Cancer Causes Control 2020 Feb 1;31(2):193-202. Epub 2020 Jan 1.

Department of Epidemiology, University of North Carolina-Chapel Hill Gillings School of Global Public Health, Chapel Hill, USA.

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http://dx.doi.org/10.1007/s10552-019-01261-4DOI Listing
February 2020

Urinary Cotinine Is as Good a Biomarker as Serum Cotinine for Cigarette Smoking Exposure and Lung Cancer Risk Prediction.

Cancer Epidemiol Biomarkers Prev 2020 01 4;29(1):127-132. Epub 2019 Nov 4.

Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1055-9965.EPI-19-0653DOI Listing
January 2020

Three dimensional in vitro models of cancer: Bioprinting multilineage glioblastoma models.

Adv Biol Regul 2020 01 17;75:100658. Epub 2019 Oct 17.

Institute of Biological Chemistry, Biophysics & Bioengineering, Heriot Watt University, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jbior.2019.100658DOI Listing
January 2020

Flow, Reflected by Stroke Volume Index, Is a Risk Marker in High-Gradient Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement.

Can J Cardiol 2020 01 29;36(1):112-118. Epub 2019 Aug 29.

Department of Cardiology, Royal Victoria Hospital, Belfast, United Kingdom.

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http://dx.doi.org/10.1016/j.cjca.2019.08.030DOI Listing
January 2020

A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer.

J Natl Cancer Inst 2020 Jan 9. Epub 2020 Jan 9.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/jnci/djz246DOI Listing
January 2020

Genetically Determined Height and Risk of Non-hodgkin Lymphoma.

Front Oncol 2019 28;9:1539. Epub 2020 Jan 28.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fonc.2019.01539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999122PMC
January 2020

Diverse presentations of cutaneous mosaicism occur in CYLD cutaneous syndrome and may result in parent-to-child transmission.

J Am Acad Dermatol 2019 Dec 11;81(6):1300-1307. Epub 2019 May 11.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2019.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878220PMC
December 2019

Vertebroplasty for acute painful osteoporotic vertebral compression fractures: An update.

J Med Imaging Radiat Oncol 2019 Dec 20;63(6):779-785. Epub 2019 May 20.

Interventional Radiology Service - Department of Radiology, Austin Hospital, Melbourne, Victoria, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1754-9485.12
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http://dx.doi.org/10.1111/1754-9485.12900DOI Listing
December 2019

Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1.

ACS Med Chem Lett 2019 Dec 25;10(12):1661-1666. Epub 2019 Nov 25.

Institute of Pharmaceutical Chemistry, Goethe-University Frankfurt, 60438 Frankfurt, Germany.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912866PMC
December 2019

Long-term Survival in Head and Neck Cancer: Impact of Site, Stage, Smoking, and Human Papillomavirus Status.

Laryngoscope 2019 11 13;129(11):2506-2513. Epub 2019 Jan 13.

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St. Louis, St. Louis, Missouri, U.S.A.

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http://doi.wiley.com/10.1002/lary.27807
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http://dx.doi.org/10.1002/lary.27807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907689PMC
November 2019

Quantitative assessment of the conjunctival microcirculation using a smartphone and slit-lamp biomicroscope.

Microvasc Res 2019 11 19;126:103907. Epub 2019 Jul 19.

Biomedical Sciences Research Institute, Ulster University, Coleraine BT521SA, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.mvr.2019.103907DOI Listing
November 2019

Developing infrared spectroscopic detection for stratifying brain tumour patients: glioblastoma multiforme vs. lymphoma.

Analyst 2019 Nov;144(22):6736-6750

WestCHEM, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George St, Glasgow, G1 1RD, UK.

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http://dx.doi.org/10.1039/c9an01731cDOI Listing
November 2019

Acceptability, Feasibility and Preliminary Evaluation of a Novel, Personalised, Home-Based Physical Activity Intervention for Chronic Heart Failure (Active-at-Home-HF): a Pilot Study.

Sports Med Open 2019 Nov 27;5(1):45. Epub 2019 Nov 27.

Cardiovascular Research Theme, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, William Leech Building M4.074, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1186/s40798-019-0216-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881484PMC
November 2019

Sex specific associations in genome wide association analysis of renal cell carcinoma.

Authors:
Ruhina S Laskar David C Muller Peng Li Mitchell J Machiela Yuanqing Ye Valerie Gaborieau Matthieu Foll Jonathan N Hofmann Leandro Colli Joshua N Sampson Zhaoming Wang Delphine Bacq-Daian Anne Boland Behnoush Abedi-Ardekani Geoffroy Durand Florence Le Calvez-Kelm Nivonirina Robinot Helene Blanche Egor Prokhortchouk Konstantin G Skryabin Laurie Burdett Meredith Yeager Sanja Radojevic-Skodric Slavisa Savic Lenka Foretova Ivana Holcatova Vladimir Janout Dana Mates Stefan Rascu Anush Mukeria David Zaridze Vladimir Bencko Cezary Cybulski Eleonora Fabianova Viorel Jinga Jolanta Lissowska Jan Lubinski Marie Navratilova Peter Rudnai Beata Świątkowska Simone Benhamou Geraldine Cancel-Tassin Olivier Cussenot Antonia Trichopoulou Elio Riboli Kim Overvad Salvatore Panico Borje Ljungberg Raviprakash T Sitaram Graham G Giles Roger L Milne Gianluca Severi Fiona Bruinsma Tony Fletcher Kvetoslava Koppova Susanna C Larsson Alicja Wolk Rosamonde E Banks Peter J Selby Douglas F Easton Paul Pharoah Gabriella Andreotti Laura E Beane Freeman Stella Koutros Demetrius Albanes Satu Männistö Stephanie Weinstein Peter E Clark Todd L Edwards Loren Lipworth Hallie Carol Matthew L Freedman Mark M Pomerantz Eunyoung Cho Peter Kraft Mark A Preston Kathryn M Wilson J Michael Gaziano Howard D Sesso Amanda Black Neal D Freedman Wen-Yi Huang John G Anema Richard J Kahnoski Brian R Lane Sabrina L Noyes David Petillo Bin Tean Teh Ulrike Peters Emily White Garnet L Anderson Lisa Johnson Juhua Luo Wong-Ho Chow Lee E Moore Toni K Choueiri Christopher Wood Mattias Johansson James D McKay Kevin M Brown Nathaniel Rothman Mark G Lathrop Jean-Francois Deleuze Xifeng Wu Paul Brennan Stephen J Chanock Mark P Purdue Ghislaine Scelo

Eur J Hum Genet 2019 10 23;27(10):1589-1598. Epub 2019 Jun 23.

International Agency for Research on Cancer (IARC), Lyon, France.

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http://dx.doi.org/10.1038/s41431-019-0455-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777615PMC
October 2019

Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

J Med Chem 2019 10 24;62(20):8996-9007. Epub 2019 Jul 24.

Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute , Icahn School of Medicine at Mount Sinai , New York , New York 10029 , United States.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00522DOI Listing
October 2019

Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.

Genet Epidemiol 2019 10 13;43(7):844-863. Epub 2019 Aug 13.

Center for Neuroengineering and Therapeutics, Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/gepi.22242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763347PMC
October 2019

Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer.

Nat Commun 2019 10 8;10(1):4501. Epub 2019 Oct 8.

WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre, 99 George Street, Glasgow, G1 1RD, UK.

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http://dx.doi.org/10.1038/s41467-019-12527-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783469PMC
October 2019

Treatment of Visceral Artery Aneurysms Using Novel Neurointerventional Devices and Techniques.

J Vasc Interv Radiol 2019 Sep 26;30(9):1407-1417. Epub 2019 Apr 26.

Department of Interventional Radiology, Beaumont Hospital, Beaumont Road, Dublin, Ireland; Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jvir.2018.12.733DOI Listing
September 2019

The Relationship of the FOUR Score to Patient Outcome: A Systematic Review.

J Neurotrauma 2019 09 6;36(17):2469-2483. Epub 2019 Jun 6.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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https://www.liebertpub.com/doi/10.1089/neu.2018.6243
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http://dx.doi.org/10.1089/neu.2018.6243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709730PMC
September 2019

Reply.

Gastroenterology 2019 09 13;157(3):897-898. Epub 2019 Jul 13.

Digestive Oncology Research Center, Digestive Diseases Research Institute and Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1053/j.gastro.2019.07.016DOI Listing
September 2019

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 Sep 23;10(1):4386. Epub 2019 Sep 23.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-019-12095-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757065PMC
September 2019

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 515.33 TERT-CLPTM1Ll Region.

J Thorac Oncol 2019 08 19;14(8):1360-1369. Epub 2019 Apr 19.

Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193028
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http://dx.doi.org/10.1016/j.jtho.2019.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833942PMC
August 2019

LINE-1 Evasion of Epigenetic Repression in Humans.

Mol Cell 2019 08 20;75(3):590-604.e12. Epub 2019 Jun 20.

Mater Research Institute, University of Queensland, TRI Building, Woolloongabba, QLD 4102, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765193039
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http://dx.doi.org/10.1016/j.molcel.2019.05.024DOI Listing
August 2019

Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.

Lancet 2019 08;394(10199):672-683

Digestive Disease Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran; Liver and Pancreaticobiliary Disease Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(19)31791-XDOI Listing
August 2019

Direct carotid puncture for endovascular thrombectomy in acute ischemic stroke.

J Neurointerv Surg 2019 Jul 6;11(7):647-652. Epub 2019 Apr 6.

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1136/neurintsurg-2018-014586DOI Listing
July 2019

Advances in Clinical Cardiology 2018: A Summary of Key Clinical Trials.

Adv Ther 2019 07 7;36(7):1549-1573. Epub 2019 May 7.

Craigavon Cardiac Centre, SHSCT, Craigavon, Northern Ireland, UK.

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http://dx.doi.org/10.1007/s12325-019-00962-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824396PMC
July 2019

Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach.

Oral Oncol 2019 07 17;94:47-57. Epub 2019 May 17.

Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy.

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http://dx.doi.org/10.1016/j.oraloncology.2019.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117823PMC
July 2019

Forty-year-old man with dyspnoea, haemoptysis and night sweats.

Heart 2019 06 16;105(12):919-925. Epub 2019 Feb 16.

Department of Cardiology, Royal Victoria Hospital, Belfast, UK.

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http://dx.doi.org/10.1136/heartjnl-2018-314511DOI Listing
June 2019

Commentary: What can Mendelian randomization tell us about causes of cancer?

Int J Epidemiol 2019 06;48(3):816-821

Section of Genetics, International Agency for Research on Cancer (IARC), Lyon, France.

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http://dx.doi.org/10.1093/ije/dyz151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659369PMC
June 2019

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.

Cancer Epidemiol Biomarkers Prev 2019 05 30;28(5):935-942. Epub 2019 Jan 30.

Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075698PMC
May 2019

Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.

J Med Chem 2019 05 30;62(9):4526-4542. Epub 2019 Apr 30.

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital , Sichuan University , Chengdu 610041 , P. R. China.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00096DOI Listing
May 2019

Considering the optimal procedural Heart Team in TAVI: back to the future?

EuroIntervention 2019 Apr 5;14(18):e1802-e1805. Epub 2019 Apr 5.

Department of Cardiology, Royal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, Northern Ireland, United Kingdom.

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http://dx.doi.org/10.4244/EIJV14I18A315DOI Listing
April 2019

Nivolumab and immune-mediated colitis.

Clin Case Rep 2019 Apr 19;7(4):644-647. Epub 2019 Feb 19.

Department of Pathology Ninewells Hospital and Medical School Dundee UK.

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http://dx.doi.org/10.1002/ccr3.2027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452469PMC
April 2019

Self-expanding CENTERA valve for the treatment of severe, symptomatic aortic stenosis.

Future Cardiol 2019 03 9;15(2):79-84. Epub 2019 Jan 9.

Department of Cardiology, Royal Victoria Hospital, Belfast Health & Social Care Trust, Belfast, Country Antrim, Northern Ireland, BT12 6BA.

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https://www.futuremedicine.com/doi/10.2217/fca-2018-0074
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http://dx.doi.org/10.2217/fca-2018-0074DOI Listing
March 2019

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.

Oncotarget 2019 Mar 5;10(19):1760-1774. Epub 2019 Mar 5.

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.18632/oncotarget.26678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442994PMC
March 2019

Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019

Extracranial and Intracranial Vasculopathy With "Moyamoya Phenomenon" in Association With Alagille Syndrome.

Front Neurol 2018 29;9:1194. Epub 2019 Jan 29.

Department of Neurology, The Adelaide and Meath Hospital, Dublin, Incorporating The National Children's Hospital (AMNCH)/Tallaght University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.3389/fneur.2018.01194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362309PMC
January 2019