Paul A Wade

Paul A Wade

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Paul A Wade

Publications by authors named "Paul A Wade"

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Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet.

Nat Commun 2020 Feb 19;11(1):962. Epub 2020 Feb 19.

Eukaryotic Transcriptional Regulation Group, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41467-020-14796-xDOI Listing
February 2020

Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

Nat Commun 2019 May 2;10(1):2079. Epub 2019 May 2.

CHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.

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http://dx.doi.org/10.1038/s41467-019-10161-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497626PMC
May 2019

Maternal Influence and Murine Housing Confound Impact of NLRP1 Inflammasome on Microbiome Composition.

J Innate Immun 2019 13;11(5):416-431. Epub 2019 Feb 13.

Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, Virginia, USA,

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http://dx.doi.org/10.1159/000495850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738257PMC
February 2019

Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

Nat Commun 2019 02 15;10(1):883. Epub 2019 Feb 15.

CHU Sainte-Justine Research Center, Montreal, QC, H3T 1C5, Canada.

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http://dx.doi.org/10.1038/s41467-019-08800-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377600PMC
February 2019

CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

Nat Commun 2018 11 5;9(1):4619. Epub 2018 Nov 5.

CHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.

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http://www.nature.com/articles/s41467-018-06014-6
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http://dx.doi.org/10.1038/s41467-018-06014-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218476PMC
November 2018

Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver.

Sci Rep 2018 07 4;8(1):10138. Epub 2018 Jul 4.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://www.nature.com/articles/s41598-018-28356-3
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http://dx.doi.org/10.1038/s41598-018-28356-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031675PMC
July 2018

CHD4 and the NuRD complex directly control cardiac sarcomere formation.

Proc Natl Acad Sci U S A 2018 06 11;115(26):6727-6732. Epub 2018 Jun 11.

University of North Carolina McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;

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http://dx.doi.org/10.1073/pnas.1722219115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042121PMC
June 2018

DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure.

Proc Natl Acad Sci U S A 2018 05 16;115(18):E4189-E4198. Epub 2018 Apr 16.

Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;

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http://dx.doi.org/10.1073/pnas.1719010115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939078PMC
May 2018

DNA Methylation Changes in Tbx3 in a Mouse Model Exposed to Polybrominated Diphenyl Ethers.

Int J Toxicol 2017 May/Jun;36(3):229-238. Epub 2017 May 3.

1 Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1177/1091581817706676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477986PMC
March 2018

Base-Resolution Analysis of DNA Methylation Patterns Downstream of in Mouse Naïve B Cells.

G3 (Bethesda) 2018 03 2;8(3):805-813. Epub 2018 Mar 2.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709

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http://dx.doi.org/10.1534/g3.117.300446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844302PMC
March 2018

GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network.

Nat Commun 2018 03 13;9(1):1059. Epub 2018 Mar 13.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, 27709, USA.

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http://www.nature.com/articles/s41467-018-03478-4
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http://dx.doi.org/10.1038/s41467-018-03478-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849768PMC
March 2018

Cryo-EM structure of the nucleosome containing the enhancer DNA sequence.

Open Biol 2018 03;8(3)

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan

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http://dx.doi.org/10.1098/rsob.170255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881032PMC
March 2018

Crosstalk between the microbiome and epigenome: messages from bugs.

J Biochem 2018 Feb;163(2):105-112

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/jb/mvx080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892391PMC
February 2018

Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer.

Cell Rep 2018 01;22(3):624-637

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.12.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793878PMC
January 2018

An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression.

Genome Biol 2018 01 23;19(1). Epub 2018 Jan 23.

Eukaryotic Transcriptional Regulation Group, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1186/s13059-018-1389-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782396PMC
January 2018

Rif1 promotes a repressive chromatin state to safeguard against endogenous retrovirus activation.

Nucleic Acids Res 2017 Dec;45(22):12723-12738

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, RTP, NC 27709, USA.

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http://dx.doi.org/10.1093/nar/gkx884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727408PMC
December 2017

Reversing SKI-SMAD4-mediated suppression is essential for T17 cell differentiation.

Nature 2017 11 25;551(7678):105-109. Epub 2017 Oct 25.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1038/nature24283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743442PMC
November 2017

Proteins That Read DNA Methylation.

Adv Exp Med Biol 2016 ;945:303-320

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Durham, NC, USA.

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http://dx.doi.org/10.1007/978-3-319-43624-1_13DOI Listing
June 2017

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.

Cancer Cell 2016 07 23;30(1):92-107. Epub 2016 Jun 23.

Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945461PMC
July 2016

High-quality ChIP-seq analysis of MBD3 in human breast cancer cells.

Genom Data 2016 Mar 6;7:173-4. Epub 2016 Jan 6.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, USA.

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http://dx.doi.org/10.1016/j.gdata.2015.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778645PMC
March 2016

GATA3 in Breast Cancer: Tumor Suppressor or Oncogene?

Gene Expr 2015 ;16(4):163-8

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Science, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.3727/105221615X14399878166113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758516PMC
February 2016

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler.

Genome Biol 2016 Feb 27;17:36. Epub 2016 Feb 27.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1186/s13059-016-0897-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769547PMC
February 2016

Genome-wide binding of MBD2 reveals strong preference for highly methylated loci.

PLoS One 2014 13;9(6):e99603. Epub 2014 Jun 13.

Department of Molecular Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099603PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057170PMC
October 2015

Epigenetic control of Ccr7 expression in distinct lineages of lung dendritic cells.

J Immunol 2014 Nov 8;193(10):4904-13. Epub 2014 Oct 8.

Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709; and

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http://dx.doi.org/10.4049/jimmunol.1401104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225164PMC
November 2014

MBD3 localizes at promoters, gene bodies and enhancers of active genes.

PLoS Genet 2013 26;9(12):e1004028. Epub 2013 Dec 26.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873231PMC
August 2014

Are genomic translocations predictable? (Retrospective on DOI 10.1002/bies.201100122).

Authors:
Paul A Wade

Bioessays 2014 Jul 19;36(7):633. Epub 2014 Apr 19.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Science Research, Triangle Park, NC, USA.

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http://dx.doi.org/10.1002/bies.201400050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145595PMC
July 2014

Fine-tuning of epigenetic regulation with respect to promoter CpG content in a cell type-specific manner.

Epigenetics 2014 May 12;9(5):747-59. Epub 2014 Feb 12.

Laboratory of Molecular Carcinogenesis; National Institute of Environmental Health Sciences; Research Triangle Park, NC USA.

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http://dx.doi.org/10.4161/epi.28075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063834PMC
May 2014

Inhibition of histone binding by supramolecular hosts.

Biochem J 2014 May;459(3):505-12

*Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, U.S.A.

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http://dx.doi.org/10.1042/BJ20140145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454452PMC
May 2014

INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development.

Cell Stem Cell 2014 May;14(5):575-91

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154226PMC
May 2014

Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover.

BMC Cancer 2014 Apr 22;14:278. Epub 2014 Apr 22.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, 111 T,W, Alexander Dr, 27709 Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1186/1471-2407-14-278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021073PMC
April 2014

Epigenetics and the adaptive immune response.

Mol Aspects Med 2013 Jul-Aug;34(4):813-25. Epub 2012 Jul 10.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.mam.2012.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508324PMC
December 2013

DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation.

Genome Res 2013 Dec 6;23(12):2030-41. Epub 2013 Sep 6.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA;

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http://dx.doi.org/10.1101/gr.155473.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847773PMC
December 2013

The NuRD architecture.

Cell Mol Life Sci 2013 Oct 23;70(19):3513-24. Epub 2013 Jan 23.

Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s00018-012-1256-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652912PMC
October 2013

NuRD and pluripotency: a complex balancing act.

Cell Stem Cell 2012 May;10(5):497-503

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.stem.2012.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348611PMC
May 2012

Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity.

Nucleic Acids Res 2012 Apr 30;40(8):3364-77. Epub 2011 Dec 30.

Systems Biology Section, Biostatistics Branch, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), 111 TW Alexander Drive, Research Triangle Park, NC 27709, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkr1253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333871PMC
April 2012

Metastasis-associated protein 3 (MTA3) regulates G2/M progression in proliferating mouse granulosa cells.

Biol Reprod 2012 Mar 8;86(3):1-8. Epub 2012 Mar 8.

Reproductive Medicine Group, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1095/biolreprod.111.096032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316264PMC
March 2012

R loops: lassoing DNA methylation at CpGi.

Mol Cell 2012 Mar;45(6):708-9

Department of Radiation Oncology and the Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30307, USA.

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http://dx.doi.org/10.1016/j.molcel.2012.03.014DOI Listing
March 2012

The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.

PLoS One 2011 20;6(10):e26514. Epub 2011 Oct 20.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026514PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197668PMC
February 2012

DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines.

Int J Cancer 2012 Jan 25;130(2):267-77. Epub 2011 May 25.

Laboratory of Molecular Carcinogenesis, NIEHS, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1002/ijc.26082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133861PMC
January 2012

Human tRNA genes function as chromatin insulators.

EMBO J 2012 Jan 15;31(2):330-50. Epub 2011 Nov 15.

Department of MCD Biology, University of California, Santa Cruz, CA, USA.

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http://dx.doi.org/10.1038/emboj.2011.406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261562PMC
January 2012

Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin.

Mol Biol Cell 2011 Sep 7;22(17):3094-102. Epub 2011 Jul 7.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1091/mbc.E11-03-0258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164457PMC
September 2011

Cancer biology and NuRD: a multifaceted chromatin remodelling complex.

Nat Rev Cancer 2011 Jul 7;11(8):588-96. Epub 2011 Jul 7.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina NC 27709, USA.

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http://dx.doi.org/10.1038/nrc3091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157524PMC
July 2011

SnapShot: Chromatin remodeling: CHD.

Cell 2011 Feb;144(4):626-626.e1

Laboratory of Molecular Carcinogenesis, NIEHS, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.cell.2011.02.019DOI Listing
February 2011

DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.

J Exp Med 2010 Aug 23;207(9):1939-50. Epub 2010 Aug 23.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1084/jem.20100204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931164PMC
August 2010

Epstein-Barr virus infection leads to partial phenotypic reversion of terminally differentiated malignant B cells.

Cancer Lett 2009 Nov 28;284(2):165-74. Epub 2009 May 28.

Istituto Pasteur-Fondazione Cenci-Bolognetti, Department of Experimental Medicine and Pathology, University of Rome La Sapienza Viale Regina Elena 324, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.canlet.2009.04.025DOI Listing
November 2009

The Mi-2/NuRD complex associates with pericentromeric heterochromatin during S phase in rapidly proliferating lymphoid cells.

Chromosoma 2009 Aug 19;118(4):445-57. Epub 2009 Mar 19.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1007/s00412-009-0207-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808998PMC
August 2009

Yin yang 1 regulates the expression of snail through a distal enhancer.

Mol Cancer Res 2009 Feb 10;7(2):221-9. Epub 2009 Feb 10.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819842PMC
February 2009

The MBD protein family-reading an epigenetic mark?

Mutat Res 2008 Dec 22;647(1-2):39-43. Epub 2008 Jul 22.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Science, Research Triangle Park, NC 27517, USA.

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http://dx.doi.org/10.1016/j.mrfmmm.2008.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670759PMC
December 2008

The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha.

Mol Endocrinol 2007 Dec 30;21(12):2907-18. Epub 2007 Aug 30.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, P.O. Box 12233, 111 TW Alexander Drive, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1210/me.2007-0293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668600PMC
December 2007

A 3' enhancer controls snail expression in melanoma cells.

Cancer Res 2007 Jul;67(13):6113-20

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4256DOI Listing
July 2007

Structure of the SANT domain from the Xenopus chromatin remodeling factor ISWI.

Proteins 2007 Jun;67(4):1198-202

Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1002/prot.21352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688785PMC
June 2007

Intrinsic disorder and autonomous domain function in the multifunctional nuclear protein, MeCP2.

J Biol Chem 2007 May 19;282(20):15057-64. Epub 2007 Mar 19.

Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA.

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http://dx.doi.org/10.1074/jbc.M700855200DOI Listing
May 2007

MeCP2 in Rett syndrome: transcriptional repressor or chromatin architectural protein?

Curr Opin Genet Dev 2007 Apr 20;17(2):121-5. Epub 2007 Feb 20.

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.gde.2007.02.003DOI Listing
April 2007

MBD family proteins: reading the epigenetic code.

J Cell Sci 2006 Aug;119(Pt 15):3033-7

Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Science, 111 TW Alexander Drive, Mail Drop D4-04, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1242/jcs.03099DOI Listing
August 2006

Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase.

EMBO J 2006 May 27;25(10):2083-95. Epub 2006 Apr 27.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1038/sj.emboj.7601111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462972PMC
May 2006

Nucleophosmin/B23, a nuclear PI(3,4,5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD.

Mol Cell 2005 May;18(4):435-45

Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1016/j.molcel.2005.04.010DOI Listing
May 2005

SWItching off methylated DNA.

Authors:
Paul A Wade

Nat Genet 2005 Mar;37(3):212-3

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http://dx.doi.org/10.1038/ng0305-212DOI Listing
March 2005

Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells.

Mol Endocrinol 2004 Dec 9;18(12):2937-49. Epub 2004 Sep 9.

Department of Pathology, Emory University, Whitehead Building Room 142, 615 Michael Street, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1210/me.2004-0258DOI Listing
December 2004

MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation.

Cell 2004 Oct;119(1):75-86

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.cell.2004.09.014DOI Listing
October 2004

Nuclear transfer: epigenetics pays a visit.

Nat Cell Biol 2004 Oct;6(10):920-2

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http://dx.doi.org/10.1038/ncb1004-920DOI Listing
October 2004

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress.

Mol Cell Biol 2004 Sep;24(17):7559-66

Department of Pathology and Laboratory Medicine, Winship Cancer Institute, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1128/MCB.24.17.7559-7566.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC506998PMC
September 2004

Use of bifunctional cross-linking reagents in mapping genomic distribution of chromatin remodeling complexes.

Methods 2004 May;33(1):81-5

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Whitehead Building, Room 142, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.ymeth.2003.10.022DOI Listing
May 2004

Methods for preparation and assays for Xenopus ISWI complexes.

Methods Enzymol 2004 ;377:364-75

Emory University School of Medicine, Department of Pathology and Laboratory Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1016/S0076-6879(03)77023-2DOI Listing
April 2004

Dynamic regulation of DNA methylation coupled transcriptional repression: BDNF regulation by MeCP2.

Authors:
Paul A Wade

Bioessays 2004 Mar;26(3):217-20

Emory University, Department of Pathology and Laboratory Medicine, Whitehead Research Building Room 142, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1002/bies.20018DOI Listing
March 2004

Mi-2/NuRD: multiple complexes for many purposes.

Biochim Biophys Acta 2004 Mar;1677(1-3):52-7

Department of Genetics, University of Georgia, Athens, GA, USA.

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http://dx.doi.org/10.1016/j.bbaexp.2003.10.010DOI Listing
March 2004

Mi-2 beta associates with BRG1 and RET finger protein at the distinct regions with transcriptional activating and repressing abilities.

J Biol Chem 2003 Dec 6;278(51):51638-45. Epub 2003 Oct 6.

Department of Pathology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1074/jbc.M309198200DOI Listing
December 2003

Nucleosome sliding induced by the xMi-2 complex does not occur exclusively via a simple twist-diffusion mechanism.

J Biol Chem 2003 Aug 26;278(33):30562-8. Epub 2003 May 26.

Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M304148200DOI Listing
August 2003

Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation.

J Biol Chem 2003 Aug 4;278(34):32181-8. Epub 2003 Jun 4.

Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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http://dx.doi.org/10.1074/jbc.M305308200DOI Listing
August 2003

MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer.

Cell 2003 Apr;113(2):207-19

Emory University School of Medicine, Department of Pathology, Whitehead Biomedical Research Building, Room 142, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00234-4DOI Listing
April 2003

The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties.

Nucleic Acids Res 2003 Mar;31(6):1765-74

Cancer Epigenetics Laboratory, Molecular Pathology Program, Spanish National Cancer Center (CNIO), C/ Melchor Fernandez Almagro, no. 3, E-28029, Madrid, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152853PMC
http://dx.doi.org/10.1093/nar/gkg249DOI Listing
March 2003

Rhythmic histone acetylation underlies transcription in the mammalian circadian clock.

Nature 2003 Jan 11;421(6919):177-82. Epub 2002 Dec 11.

Department of Neurobiology, University of Massachusetts Medical School, LRB-728, 364 Plantation Street, Worcester, Massachusetts 01605, USA.

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http://dx.doi.org/10.1038/nature01314DOI Listing
January 2003

Purification of MeCP2-containing deacetylase from Xenopus laevis.

Methods Mol Biol 2002 ;200:131-41

Department of Molecular Embryology, National Institute of Child Health and Human Development, Bethesda, MD, USA.

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http://dx.doi.org/10.1385/1-59259-182-5:131DOI Listing
October 2002

The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation.

Genes Dev 2002 Jun;16(12):1540-54

Laboratory of Molecular Biology, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1101/gad.988502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC186352PMC
June 2002

WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.

EMBO J 2002 May;21(9):2231-41

Marie Curie Research Institute, Oxted, Surrey RH8 0TL, UK.

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http://dx.doi.org/10.1093/emboj/21.9.2231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125993PMC
May 2002

Chromatin remodeling in nuclear cloning.

Eur J Biochem 2002 May;269(9):2284-7

Department of Pathology, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1046/j.1432-1033.2002.02887.xDOI Listing
May 2002

Phosphorylation of linker histones regulates ATP-dependent chromatin remodeling enzymes.

Nat Struct Biol 2002 Apr;9(4):263-7

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

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http://dx.doi.org/10.1038/nsb776DOI Listing
April 2002